• Proceedings of the PSK Conference
• /
• 2003.10b
• /
• pp.141.2-142
• /
• 2003

beta-Amyloid (A$\beta$) peptide is the major component of senile plaques and considered to have a causal role in the development and progression of Alzheimer's disease. There has been compelling evidence supporting that $A\beta$-induced cytotoxicity is mediated through oxidative and/or nitrosative stress. Recently, considerable attention has been focused on dietary manipulation of oxidative and/or nitrosative damage. L-Egrothioneine (EGT) is a low-molecular weight naturally occurring thiol compound of dietary origin which exists in milimolar concentrations in the brain, liver, kindney, erythrocytes, ocular tissues and in seminal fluids of mammals. (omitted)

• The Journal of Korean Physical Therapy
• /
• v.35 no.2
• /
• pp.48-52
• /
• 2023

Purpose: This study was undertaken to determine whether the position of cane use affects the distribution of weight-bearing on both feet of children with hemiplegic cerebral palsy in a standing posture. Methods: Twenty participants with cerebral palsy were recruited as volunteers for this study. Using the Zebris FDM-System, weight-bearing distribution according to the method of using a cane was measured under three conditions in randomized order: (1) standing unaided (no cane); (2) standing with the affected side using the cane; and (3) standing with the non-affected side using the cane. The cane was matched by measuring length-from-floor to the greater trochanter of the subject, and was placed 15 cm outward from the little toe on the supporting side. Results: Evaluating the method of using a cane under the three conditions, we determined that pressure of the foot on the affected side was higher in the order: standing with affected side using cane > standing unaided (no cane) > standing with non-affected side using cane (p<0.05). In the post-hoc analysis, a significant difference was observed between (i) standing unaided (no cane) and standing with the affected side using cane, and (ii) standing with affected side using cane and standing with non-affected side using cane (p<0.05). Conclusion: This study suggests that induced weight-bearing methods using a cane on the affected side could increase the weight-bearing capacity on the affected side in children with spastic hemiplegic cerebral palsy, which will have a positive effect on reducing asymmetry weight support.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 1999.05a
• /
• pp.224-229
• /
• 1999

In distributed object oriented environment based upon wide heterogeneous network, effective cooperation policies between/among distributed objects are needed to resolve a complexity of management of distributed objects because of growing of a large stale of systems. Thus, in this paper, we propose three trading cooperation models between/among traders for supporting a high speed and a wide selection of trader service for clients, by considering three different cooperation models(light weight trader, simple negotiation and federation) depending upon their facilities, goals, and weights of goals.

• Proceedings of the Computational Structural Engineering Institute Conference
• /
• 2003.04a
• /
• pp.451-460
• /
• 2003

In this paper, high speed fiber optic sensor weigh-in motion (WIM) system is proposed. Bragg gratings which have several advantages such as good reproducibility and good multiplicity compare to other optical fiber sensors are used for the system. Fabry-Perot filter for the signal process, which cannot be used in the high speed measurement because of the limitation in fast operation of PZT, is excluded. A new signal processing system which employs bandwidth filter is proposed and bridge type new sensor package design is also proposed. Design of the mold supporter is modified to round shape and then supporting points do not change. The data from the fiber sensors show identical and linear behavior to the axle weight. The proposed fiber optic WIM system is tested in the laboratory and experimented with actual trucks. The new concept of calibration is introduced and calculated by the experiments. The calibrated weight data show good approximations to real axial weights regardless the velocities of the truck.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
• /
• 2000.10a
• /
• pp.47-52
• /
• 2000

F.R.P specimens were made by mixture CM(chopped mat) 450-104 matrix & RC(roving clothes)570-100 Roving, the mixture ratio Resin: hardener (92:8) for tensile test. It was also made of plates by hand lay-up method and was been cured for 24 hours and then was cut tensile specimens in accordance with ASTM D638 Type 3. Knowing exact behavior of bonded area's stress and strain when the tensile test was going on, the test specimens were made of 2 plies laminae of F.R.P in each for supporting cut part in middle of specimen length. And in middle part also were covered of F.R.P plies of 1/2, 2/3 length of specimen in each as well. Also we consider shear stress in adhered area. This study reveals that as plys length is more longer, rupture stress grows remarkably larger.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2006.05a
• /
• pp.63-64
• /
• 2006

In this paper, design modification was performed to improve the structure of ex-developed 12 D.O.F Biped walking robot, KUBIR-1 similar with human beings. The motion of KUBIR-1 was slow and had a limited walking space. Hence I designed an improved BWR named KUBIR-2 with 12 degree of freedom. KUBIR-2 was designed to solve the following problems of KUBIR-1. First, KUBIR-2 was more simply designed in the four-bar-link mechanism, and its weight was reduced. Second, it had the built-in controller and motor driver. Third, walking velocity of KUBIR-2 was increased by improvement of speed and motion joint angle range. In addition to these, we modified the structure of the foot for more stable walking.

• Journal of the Ergonomics Society of Korea
• /
• v.15 no.1
• /
• pp.119-132
• /
• 1996

The objectives of this study are to investigate the measurements of clothing for the handicapped compared to that of the normal, and to present the basic data to make clothing for the handicapped who has specific needs. Questionnaires were administered to 927 Cerebral Palsies on height, weight, chest circumference, sitting height, and to 70 handicapped people using a supporting parasite on 18 measurement items. The results show that height, weight , and sitting height of the handicapped are smaller than those of the normal of equal age except for chest circumference. And, the values of the items for the lower half are smaller than the normal of equal age and those for the upper half, especially the items for the shoulder and arm, are greater. Compared to the values of the normal in the three standad size charts, the size charts using height and chest circumference are unsuitable to the handicapped, and the size chart using hip circumference is approximately suitable.

• Journal of Nutrition and Health
• /
• v.56 no.4
• /
• pp.349-360
• /
• 2023

Purpose: Ketogenic diets (KDs) have anti-obesity effects that may be related to glucose control and the gut microbiota. This paper hypothesizes that KD reduces body weight and changes the insulin sensitivity and gut microbiota composition in a mouse model of diet-induced obesity. Methods: In this study, C57BL/6 male mice were assigned randomly to 3 groups. The assigned diets were provided to the control and high-fat (HF) diet groups for 14 weeks. The KD group was given a HF diet for 8 weeks to induce obesity, followed by feeding the KD for the next 6 weeks. Results: After the treatment period, the KD group exhibited a 35.82% decrease in body weight gain compared to the HF group. In addition, the KD group demonstrated enhanced glucose control, as shown by the lower levels of serum fasting glucose, serum fasting insulin, and the homeostatic model assessment of insulin resistance, compared to the HF group. An analysis of the gut microbiota using 16S ribosomal RNA sequencing revealed a significant decrease in the proportion of Firmicutes when the KD was administered. In addition, feeding the KD reduced the overall alpha-diversity measures and caused a notable separation of microbial composition compared to the HF diet group. The KD also led to a decrease in the relative abundance of specific species, such as Acetatifactor_muris, Ligilactobacillus_apodemi, and Muribaculum_intestinale, compared with the HF group. These species were positively correlated with the body weight, whereas the abundant species in the KD group (Kineothrix_alysoides and Saccharofermentans_acetigenes) showed a negative correlation with body weight. Conclusion: The current study presents supporting evidence that KD reduced the body weight and altered the insulin sensitivity and gut microbiota composition in a mouse model of diet-induced obesity.

• Korean Journal of Agricultural Science
• /
• v.47 no.2
• /
• pp.263-273
• /
• 2020

With the change of the agricultural environment (increased rice production, decreased rice consumption, and rice production policies), converting paddy fields into upland fields is an increasing trend. In terms of conversion into upland fields, subsurface drainage is one of the most important factors for good field crop growth. This study evaluates the performance of a subsurface drainage culvert system in paddy fields and reclaimed lands. The obtained results are briefly summarized as follows: 1) After a comparative evaluation of several subsurface drainage culvert systems, including excavated subsurface drainage and non-excavated subsurface drainage types, type 3 (non-excavated, perforated drain pipe 50 mm, filter mat B50 cm, subsoiling 70 cm and culvert spacing 5 m) shows relatively high values among four types in terms of effectiveness (subsurface discharge capability) and economic efficiency (construction cost). 2) Type 3 has proven that it is suitable for design standards of discharge capacity through field tests performed in paddy fields (three sites: Gong-geom, Gae-san, Juk-san) and reclaimed lands (two sites: Gum-ho, Mi-am). 3) In the experiment of Sesamum indicum growth according to the existence of a drainage system, Sesamum indicum growth with a subsurface drainage culvert system had good value in terms of plant shoot and root length, shoot fresh and dry weight, and root fresh and dry weight).

• Geomechanics and Engineering
• /
• v.8 no.5
• /
• pp.741-756
• /
• 2015

The prediction of impending collapse of deep tunnel is one of the most difficult problems. Collapse mechanism of deep tunnel in layered soils is derived using a new curved failure mechanism within the framework of upper bound theorem, and effects of seepage forces are considered. Nonlinear failure criterion is adopted in the present analysis, and the possible collapse shape of deep tunnel in the layered soils is discussed in this paper. In the layered soils, the internal energy dissipations along velocity discontinuity are calculated, and the external work rates are produced by weight, seepage forces and supporting pressure. With upper bound theorem of limit analysis, two different curve functions are proposed for the two different soil stratums. The specific shape of collapse surface is discussed, using the proposed curve functions. Effects of nonlinear coefficient, initial cohesion, pore water pressure and unit weight on potential collapse are analyzed. According to the numerical results, with the nonlinear coefficient increase, the shape of collapse block will increase. With initial cohesion of the upper soil increase, the shape of failure block will be flat, and with the lower soil improving, the size of collapsing will be large. Furthermore, the shape of collapsing will decrease with the unit weight decrease.