• Title/Summary/Keyword: weaving

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The Effects of d-Amphetamine on the Brain 5-HT, 5-HIAA, MAO and the Behavior of Rat (d-Amphetamine이 백서뇌의 5-HT, 5-HIAA, MAO 및 행동에 미치는 영향에 관한 연구)

  • Suh, Yoo-Hun;Woo, Jong-In;Park, Chan-Woong
    • The Korean Journal of Pharmacology
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    • v.17 no.2
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    • pp.47-62
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    • 1981
  • d-amphetamine이 사람에서 paranoid schizophrenia와 아주 유사한 model psychosis를 일으키며 또한 사람과 실험동물에서 실제 정신분열증에서 뚜렷이 관찰되는 behavioral perservation을 일으킬 수 있음이 관찰되었다. 이에 많은 학자들은 이러한 양상의 행동변화가 정신분열증의 원인 추구에 중요한 의미를 주는 뇌변화를 반영할지도 모른다는 생각에 많은 연구를 거듭하여 왔다. 지금까지는 주로 catecholamine기전에 대하여 집중적 연구가 수행되어져 왔으나 최근에는 d-amphetamine의 약리기전의 일부는 5-HT기전이 차지하고 있으며, 여러 행동변화에는 catecholaimin 보다 5-HT 가 더 중요하게 관계하고 있다는 주장이 나오고 있다. 또한 d-amphetamine은 시험관내에서 MAO 특히 신경전달물질 분해요소인 A type를 가역적으로 억제할 수 있음이 보고되어 많은 흥미를 끌어왔으나 생체내에서의 억제여부는 직접적으로 확인이 되고 있지 않다. 그러나 최근에 Braestrup(1977)과 El Hait(1978)등은 간접적인 방법으로 생체내에서도 억제시킬 수 있음을 보고하고 있다. 이에 저자는 d-amphetamine에 의해 야기되는 행동변화와 그 밑바탕을 이루는 생화학적 기전에 5-HT가 차지하는 역할을 알아보기 위해서 다음의 실험을 시행하였다. 첫째, d-amphetamine의 급성, 만성 투여가 5-HT의 5-HIAA 로의 turnover와 MAO활성도에 어떤 영향을 미치며, 더 나아가서 이 양자사이에 어느 정도 상관관계가 있는지를 알아보기 위해서 d-amphetamine을 투여한 후 시간 경과에 따라서 뇌내 5-HT, 5-HIAA, 5-HT turnover rate와 MAO 활성도를 측정하였다. 둘째, d-amphetamine, 5-HT 합성을 증가시키는 약물과 합성을 억제시키는 약물을 투여하고, 위의 생화학적 실험과 행동관찰을 병합 실시하여 비교분석하였다. 그 결과는 다음과 같다. 1) d-amphetamine (6 mg/kg)을 급성투여시, 뇌내 5-HT함량이 투여 1시간 후에 최고로(대조치의 123%, p<0.001) 증가되다가 이후 감소하며, 5-HIAA 함량은 처음 15분부터 감소하기 시작하다가 30분에 최저로 떨어지며(대조치의 78%, p<0.005) 이후 증가하여 24시간째는 약간 대조치 이상으로 회복되었다. 미토콘드리아 MAO활성도는 1시간째에 최저로 떨어지다가(대조치의 89%, p<0.05)이후 회복하기 시작하여 24시간째에 약간 대조치 이상으로 회복되었다. 5-HT의 turnover rate는 MAO활성도 변화와 거의 같은 변화를 보였다. 2) 만성투여시 (하루 2번, 14일간 투여)는 5-HT 함량, 5-HIAA 함량, MAO 활성도 및 5-HT turnover rate 모두가 중등도로 감소되었다. (각각 대조치의 87%, 69%, 80%, 79%). 3) MAO 활성도와 5-HT turnover rate 사이에는 높은 상관관계가 있었다. (r=0.866, p<0.001, N=94). 4) MAO 활성도의 역동학 실험에서는 대조치에 비해 투여군에서 Km 값은 의미가 있는 증가가 있었으나 $V_{max}$값은 큰 변동이 없었다. 5) d-amphetamine을 급성 투여할때는 sleeping과 lying components는 상당한 감소를 보인 반면, locomotor activity 는 1시간까지는 상당한 증가를 보였으며 용량이 적을수록 더 큰 증가가 있었다. 반면 stereotypy는 1시간까지 용량이 증가할수록 더 큰 증가가 나타나서 locomotor activity에서 stereotypy 의 증가로 이행을 나타내었다. 만성 투여시는 locomotor activity는 점차적인 감소를 보였으나 stereotypy는 점차적인 증가가 나타나서 14일쯤에는 평형에 도달하였다. 6) PCPA 단독 투여군(400 mg/kg, 3번)에 있어서는 5-HT와 5-HIAA 함량의 상당한 감소가 나타났으나 MAO 활성도와 행동에는 큰 변화를 나타내지 않았다. PCPA전 처치군에 있어서도 5-HT와 5-HIAA 함량은 마찬가지로 상당한 감소를 나타내었으나 gnawing, sniffing과 locomotor activity는 더 증가를, stereotyped head weaving, forepaw treading과 hindlimb abduction은 상당한 감소를 나타내었다. 7) L-tryptophan(100 mg/kg)단독 투여시는 5-HT 함량은 약간 증가를 나타내었으나 5-HIAA 함량은 상당한 증가를 보였다. MAO활성도나 행동은 큰 변화없었다. L-tryptophan 전처치군에 있어서는 5-HT 함량은 더 큰 증가를 보였으나, 5-HIaa 함량은 MAO 활성도는 별 변화없었으며 stereotypedlateral head waving, forepaw treading 과 hindlimb abduction은 증가를, locomotor activity, gnawing과 sniffing components는 감소를 나타내었다. 8) d-amphetamine 단독투여, 혹은 L-tryptophan 전처치, PCPA 전처치후 측정한 5-HT 함량과 stereotyped head weaving, forepaw treading, hinilimb abduction components 사이에는 높은 상관관계가 있었다(r=0.789, p<0.001). 반면 5-HT 함량과 locomotor activity, stereotyped gnawing과 sniffing components 사이에는 약한 음성의 상관관계가 있었다. (r=0.554, p <0.005). 이상의 결과로 미루어 볼때 5-HT의 5-HIAA 로의 turnover rate 는 주로 MAO 활성도에 의해서 조절되며 5-HT 기전이 d-amphetamine에 의해서 야기된 여러 행동변화 중 상당한 부분에서 중요한 역할을 하리라고 생각된다.

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Effects of Fiber Surface Modification on the Flow Characteristics and Wettability in the Resin Transfer Molding Process (섬유의 표면개질이 수지이동 성형공정에서의 유동특성 및 젖음성에 미치는 영향)

  • 김세현;이건웅;이종훈;김성우;이기준
    • The Korean Journal of Rheology
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    • v.11 no.1
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    • pp.34-43
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    • 1999
  • Flow-induced voids during resin impregnation and poor fiber wetting have known to be highly detrimental to the performance of composite parts manufactured by resin transfer molding(RTM) process. In this study, in order to overcome these serious problems encountered in RTM, the effects of surface modification by using silane coupling agent as a surface modifier on the flow characteristics, the wetting between resin and fiber, and void content were investigated. For the experiments of microscopic flow visualization and curing in a beam mold, glass fiber mats having plain weaving structure and epoxy resin were used. Modifying the fiber surface was found to result in a significant decrease of dynamic contact angle between resin and fiber and increase of wicking rate. Therefore, it was confirmed that the surface modification employed in this study could improve the wettability of reinforcing fibers as well as micro flow behavior. In addition, It was revealed that high temperature and low penetration rate of the resin are more favorable processing conditions to reduce the dynamic contact angle. However, surface modified fiber mat was found to have lower permeability than the unmodified one, which may be explained in terms of the decrease of contact time between resin and fiber owing to improvement of wetting. It was also exhibited that surface modification had a significant influence on void formation in RTM process, resulting in a decrease of overall void content due to the improvement of wetting in cured composite parts.

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Status of Industrial Environments of Some Industries in Taegu Kyungpook Area (대구지방 산업장에 있어서 건강장애요인과 작업환경검사에 대한 기업인의 수용태도 (ll))

  • Kim, Du-Hui;Seong, Su-Won
    • 월간산업보건
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    • s.8
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    • pp.4-30
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    • 1988
  • Examination of working environments was conducted to get more detailed data about harmful working environments and to make a contribution to more effective management. Study was carried out on 722 factories located in Taegu city and eight counties in Kyungpook Province, Korea, for a period of one year, from February 1 to December 30, 1986. The total number and proportion of workers exposed to harmful material was 37,697, 45.2% among 83,368 workers. The results according to exposed material were as follows: 1. In the case of noise, proportion of exceeding the 8-hour TLV was 59%, Included were nail-cutting in assembly metal manufacturing industry and weaving process in textile. 2. Dust in mill process of coal manufacturing industries exceeded the TLV of second class of dust at all parts and exceeded the TLV at 6% as a whole.: 3. The fields of industry lower than 70 lux of illumination were storage equipment of food, auto-winder of textile, painting of wood wares and coal mixing, and 44% of all cases was lower than standard. 4. As a result of temperature index investigation(WBGT), about 12% of all sujects exceeded limit value. Included parts were rolling machine and reducing room. 5. In the case of organic solvents, TLV was exceeded at about 8%, The parts exceeded TLV according to materials belonged to this category were as follows. 1) Toluene: adhesive work in assembly metal manufacturing 2) Xylene: printing and paint mixing in chemical manufacturing 3) Methyl ethytl ketone: paint mixing in all parts examined and coating machine partially in chemical manufacturing 4) Methyl isobutyl ketone: printing in chemical manufacturing 5) Acetone: vapor polishing in assembly metal manufacturing 6. Among specified chemical materials, the concentration of HC1 in the air in metal assembly manufacturing factory exceeded TLV. in one of three assembly metal manufacturing examined. Others, such as benzene, acetic acid, formic acid, sodium hydroxide, formalin, ammonia, copper, chromate etc. were lower than TLV in its indoor atmospheric concentration. As a whole, the proportion of exceeding TLV was about 0.8% 7. The concentrations of inorganic lead were lower than TLV in all parts examined. The results of this investigation show the fact that current management of working environments is not satisfactory, and so more active management is needed.

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A Method for Locating Bus Stops Considering Traffic Safety at Signalized Intersections (교통안전을 고려한 신호교차로 버스정류장 설치방법에 관한 연구)

  • Lee, Jung-Hwan;Kwon, Sung-Dae;Park, Je-Jin;Ha, Tae-Jun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.31 no.4D
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    • pp.527-538
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    • 2011
  • Currently, the only established criteria is on the location of bus stops on principal roads where uninterrupted flow mainly occurs. There are no clear guidelines on any method to locating bus stops considering the characteristics of bus operation and pedestrians. If the location or exterior of a bus stop is inappropriate, road users including bus drivers and pedestrians will be caused serious dangerous and inconvenience. In this study, the research below was performed in order to propose rational criteria for the location of bus stops integrated with or separated from speed-change lanes at signalized intersections considering smooth traffic flow and the characteristics of bus operation and pedestrians as well as traffic safety : First, the appropriate length of each of the near-side and far-side bus stops was calculated by categorizing bus stops to be constructed into those integrated with speed-change lanes and those separated from speed-change lanes. Secondly, the appropriate length of each of the bus stops divided into near-side bus stops and far-side bus stops and integrated with or separated from speed-change lanes was selected by considering the characteristics of pedestrians. Thirdly, whether the construction locations of bus stops were appropriate or not was determined based on the appropriate length of bus stops integrated with or separated from speed-change lanes, which was calculated and selected by considering traffic flow and the characteristics of pedestrians and considering traffic safety. The method for locating bus stops considering traffic flow, the characteristics of pedestrians, and traffic safety will be able to help suggestion criteria of bus stop and the location of safe and pleasant bus stops.

A Study on the Textile Design Education of College in Korea (국내 대학의 텍스타일 디자인 교육에 관한 연구)

  • Lee, Ji-Won;Lee, Song-Ja
    • Journal of Korean Home Economics Education Association
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    • v.19 no.1 s.43
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    • pp.149-162
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    • 2007
  • Fashion industry that is apparel of the latest textile industry become the center and it is universal inclination that addend value of design is high more and our country apparel industry is accelerating change by life culture industry of the high added value center. Differentiation of goods, high added value anger can be required by activation of professional manpower for strengthening competitiveness of domestic apparel field, and it is design to be texture another thing can raise this. Specific education to train able member of society based on these actual conditions grasping society actual conditions in present age that is specialized and diversifies and atomizes should be achieved. Hereupon, we have researched over current education status about domestic textile related courses and come to a conclusion described below. Domestic textile related courses are offering mostly in weaving and staining as major subjects, therefore distinguished character of each university can not be found. However, in comparison of importance between theoretical courses and practical courses, theoretical courses are gradually considered more importantly And the number of courses about commodity and operation is steadily increasing compared to those of design element. Nevertheless, for the concept of creativity as design education ever been pursuing by experiment and practice, we are also required to keep close relationship with industry as well as making efforts to reduce differences between college education and practical business. In addition, textile related colleges also need to be armed with more professional knowledge in odor to provide their students not only with more job opportunities but also with chances for self-development.

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A Study on the Characteristics of Knitwear Fashion Design: With a focus on Missoni, Sonia Rykiel, Azzedine Alaia

  • Chun, Hei Jung;Park, Jae Min
    • International Journal of Costume and Fashion
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    • v.13 no.1
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    • pp.23-34
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    • 2013
  • The purpose of this study is to better understand the development and characteristics of knitwear fashion design by examining the transformation process of the modern knits. The subjects of the study are Missoni, Sonia Rykiel, and Azzedine Alaia, designers who are world-renowned knit designers, and the expressive techniques in their designs will be evaluated. The study also intends to analyze the aesthetic value of each designer's style through their product's silhouette, colors, and knitting techniques. On the basis of the analysis, we hope to research the factors in the designing process that will allow knits, which were made for practical purposes, to be valued as a luxury fashion item, and with the results, show the potential for knits in expanding its domain in fashion to become a more luxurious, creative fashion item. The characteristic comparison of the designers is as follows: First, in the case of colors, Missoni shows its distinct identity through a balance of splashy colors as well as nature-inspired color composition and balance. And, only with color use, is also able to express perspective, form composition, and rhythm. Sonia Rykiel designs are composed of black backgrounds with strong primary colors that are contrasted with one-point or stripes to express a light, urban image. Alaia emphasizes femininity by the use of black and white colors, which show modernity, in combination with neutral skin-toned colors, such as beige and gray. So, in other words, Missoni and Sonia Rykiel mixed colors for visual interconnectivity, while Alaia expressed femininity through the use of an achromatic color. Second, in the case of knitting techniques, Missoni uses the jacquard technique to make complex patterns that show balance of colors and patterns such as zigzag, stripe, geometries, and titan check, which are geometric, abstract, and symmetric. Sonia Rykiel who uses stripes as her trademark, most often utilizes the intarsia technique, which is expressed through one-point. Alaia combines diverse techniques, such as the Skashi weaving, by using computerized knitting. Third, as for silhouettes, Missoni eliminated exaggerated details in order to emphasize the flashy colors and delicate patterns and weavings of its designs, and this resulted in simplistic and relaxed silhouettes. Sonia Rykiel took advantage of the elasticity that the knit offers to get a tight silhouette, and in turn, emphasized the female sensuality. Alaia used curvilinear cuts that emphasized the womanly curves and gained an image considered soft and feminine.

Patterns of Mercury Concentrations in Blood and Urine After High Mercury Exposure (고농도 수은 노출자의 혈 중 및 뇨 중 수은 농도 변화에 관한 연구)

  • 윤충식;임상혁;하권철
    • Journal of Environmental Health Sciences
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    • v.27 no.3
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    • pp.71-80
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    • 2001
  • Blood and urine mercury level of three workers were monitored during 60~80 days after high exposure to mercury at the silver refining plant. Mercury was used to form silver-mercury amalgam from plating sludge. Workers were exposed to mercury about 70 days at the several processes, such as hand held weaving, vibration table, and heating from the furnace. mercury was analysed by atomic absorption spectroscopy-vapor generation technique. Recovery from the biological sample was 95.51% and pooled standard deviation was 0.033. At the time of study, there was no work at the workplace. So, airborne mercury concentration was measured with area sampling 5 days after the work, ranged from 0.1459 to 1.2351 mg/㎥(Arithmatic mean 0.4711 mg/㎥, Geometric mean 0.3566 mg/㎥) at the inside of the plant, that is far above the ACGIH's TLV(0.025 mg/㎥) and ranged from 0.0073 to 0.0330 mg/㎥ at the outdoor. Blood mercury levels at the beginning of the monitoring were 4~14 times greater than the American Conference of Governmental Industrial Hygienists Biological Exposure Index(ACGIH BEI, 15 ug/L). Blood mercury levels were decreased logarithmically, that is, rapidly at the high level and slowly at the low level but sustained above the level of the ACGIH BEI 60~80 days after the work. Urine mercury levels at the beginning of the monitoring were 8~16 times greater than the ACGIH BEI(35 ug/g creatinine). Urine mercury levels were decreased logarithmically, but correlation between urine level and off-days were lower than those of blood. Decreasing pattern of blood mercury levels were little affected than that of urine levels when the chelating agent, D-penicillamine, was administered. There was correlation between blood mercury level and urine mercury level(0.81~0.83) but it didn\`t mean that the highest blood mercury level corresponded the highest urine mercury level. In our study, Case 1 always shows the highest level in urine but case 3 always shows the highest level in blood. Creatinine correction represented better correlations between urine mercury levels and blood levels, and between urine levels and off-days rather than by urine volume. Spot urine sampling had a wide variation than that of whole day urine sampling. So, We recommend spot urine sampling for screening and whole day urine sampling for exact diagnosis.

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An Experimental Study on the Effect of Capillary Pressure on the Void Formation in Resin Transfer Molding Process (수지이동 성형공정에서 기공형성에 미치는 모세관압의 영향에 관한 실험적 연구)

  • 이종훈;김세훈;김성우;이기준
    • The Korean Journal of Rheology
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    • v.10 no.4
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    • pp.185-194
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    • 1998
  • Flow-induced voids during resin impregnation and poor fiber wetting give serious effects on the mechanical properties of composites in resin transfer molding process. In order to better understand the characteristics of resin flow and to investigate the mechanism of void formation, flow visualization experiment for the resin impregnation was carried out on plain weaving glass fiber mats using silicon oils with various viscosity values. The permeability and the capillary pressure for the fiber mats of different porosities were obtained by measuring the penetration length of the resin with time and with various injection pressure. At low porosity and low operating pressure, the capillary pressure played a significant role in impregnation process. Video-assisted microscopy was used in taking the magnified photograph of the flow front of the resin to investigate the effect of the capillary pressure on the void formation. The results showed that the voids were formed easily when the capillary pressure was relatively high. No voids were detected above the critical capillary number of 2.75$\times$$10^{-3}, and below the critical number the void content increased exponentially with decrease of the capillary number. The content of void formed was independent of the viscosity of the resin. For a given capillary number, the void content reduced with the lower porosity of the fiber mat.

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A Study on Implementation of Robot Overlay Welding System Based on OLP for Ball of Ball Valves (볼밸브용 볼의 OLP 기반 로봇육성용접 시스템 구현에 관한 연구)

  • Jang, Jae-Sung;Hwang, Seong-Hyun;Lho, Tae-Jung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.12
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    • pp.446-452
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    • 2016
  • Recently, heat resistant super alloys (which are wear-resistant, corrosion-resistant, and heat-resistant), have been used as the basic structural material in offshore and petrochemical plants. On the other hand, making valves from very expensive, high heat-resistant alloys increases the production cost and decreases its market competitiveness. To solve these problems, the technique of overlaying only those that flow on the fluid has been used as an effective method. Nevertheless, because the former technique of overlaying the ball is performed manually, it takes too much time and perfect welding is difficult to perform. To solve this problem, this study developed a robot automation system that can make uniformly overlay welding of the ball for ball-valves. The system consists of a 6-axis welding robot with a welding torch and additional 2 axes for the rotation of positioner, the controller, and a robot path OLP (Off-Line Programming). The CAD drawing data was entered in the Off-line program to obtain the robot teaching point and drive source. Overlay welding paths were implemented using Matlab. Through an automated overlaying system that implemented the OLP, the productivity rose 2.58 times, as the amount of time required for work decreased from 88 hours to 41 hours.

Shear Strength of Reinforced Glulam-bolt Connection by Glass Fiber Combination (유리섬유 조합에 따른 보강 집성재 볼트접합부의 전단강도 특성)

  • Kim, Keon-Ho;Song, Yo-Jin;Hong, Soon-Il
    • Journal of the Korean Wood Science and Technology
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    • v.41 no.1
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    • pp.51-57
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    • 2013
  • In order to know the shear performances of a bolted connection in reinforced glulam depending upon the combination of textile glass fiber, a tensile-type shear test was conducted. Textile glass fiber was used as a reinforcement, whose glass fiber arrangement was a plain weaving type or a diagonal cloth type. Reinforced glulam was made up of 5 plies and it was produced by inserting and laminating the plies between laminas depending upon a changed insert position and combination form of textile glass fiber. Tensile-type shear test specimens were a steel plate insert-type and joined at end-distance 7D with bolts whose diameter 12 or 16 mm. In textile glass fiber reinforced glulam, whose volume ratio was 1%, the yield shear strength of a 12 mm bolted connection increased by 10% when a test specimen had reinforced internal layers than when external layers were reinforced. As for textile glass fiber reinforced glulam, whose volume ratio was 2%, the yield shear strength of a 12 mm bolted connection increased significantly by about 22% compared to the bolted connection of non-reinforced glulam, and the yield shear strength of a 16 mm bolted connection was improved by about 20% compared to the bolted connection of non-reinforced glulam.