• Title/Summary/Keyword: virus spread

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A Study on the Sustainability of Library Service in the Situation of Infectious Diseases (감염병 상황에서의 도서관 서비스 지속가능성에 대한 연구)

  • Kim, Sungwon
    • Journal of the Korean Society for Library and Information Science
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    • v.54 no.2
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    • pp.247-267
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    • 2020
  • Libraries are public institutions in charge of information distribution. Libraries need to secure sustainability in providing services so that they can contribute to social integration even in disaster situations. The recent spread of the Corona 19 virus has negatively affected the operation of libraries and libraries have suspended services and users' visits to prevent possible infections. This study intends to examine responses of domestic and foreign libraries to the unexpected disasters, and also presents measures to ensure sustainability and considerations in establishing these measures.

Role of 5'-UTR hairpins of the Turnip yellow mosaic virus RNA in replication and systemic movement

  • Shin, Hyun-Il;Cho, Nam-Jeong;Cho, Tae-Ju
    • BMB Reports
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    • v.41 no.11
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    • pp.778-783
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    • 2008
  • Turnip yellow mosaic virus (TYMV) RNA has two hairpins in its 5' untranslated region (5'-UTR). To investigate the role of the hairpins in replication of TYMV, mutants lacking one or both of the two hairpins were constructed. The TYMV constructs were introduced into Chinese cabbage by an Agrobacterium-mediated T-DNA transfer method, called agroinfiltration. Analysis of total RNA from agroinfiltrated leaves showed that replication of the mutant TYMV RNA lacking both hairpins was about 1/100 of wild type. This mutant was also impaired in systemic spread. Deletion analysis of each hairpin revealed that both hairpins were needed for maximal replication. The deletion analysis along with sequence modification of the hairpin structure indicates that the second hairpin plays a role in efficient long-distance systemic movement of TYMV.

A Preliminary Study of the Transmission Dynamics of HIV Infection and AIDS (HIV 감염과 AIDS의 전파 특성에 관한 기초적 연구)

  • 정형환;이광우
    • Journal of Biomedical Engineering Research
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    • v.15 no.3
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    • pp.295-304
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    • 1994
  • This paper describes some preliminary attempts to formulate simple mathematical models of the transmission dynamics of HIV infection in homosexual communities. In conjunction with a survey of the available epidemiological data on HIV infection and the incidence of AIDS, the model is used to assess how various processes influence the course of the initial epidemic following the introduction of the virus. Models of the early stages of viral spread provide crude methods for estimating the basic reproductive rate of the virus, given a knowledge of the incubation period of AIDS and the initial doubling time of the epidemic. More complex models are formulated to assess the influence of heterogeneity in sexual activity. This latter factor is shown to have a major effect on the predicted pattern of the epidemic.

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White Spot Syndrome Virus(WSSV) and Hepatopancreatic Parvovirus (HPV)Infection of Penaeus chinensis in Korea

  • K. V. Rajendran;S. J. Jung;Kim, Y. J.;Kim, S. R.;M. J. Oh
    • Proceedings of the Korean Society of Fisheries Technology Conference
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    • 2001.05a
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    • pp.521-523
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    • 2001
  • White spot syndrome virus (WSSV) causes the most serious epizootic in cultured penaeid shrimp. The epizootic started in 1992, and spread through east and south east Asia and into other shrimp growing countries of the region. WSSV has also been reported from Penaeus chinensis cultured in Korean peninsula (Park et al., 1998; Kim et al., 1999). However, this paper deals with the WSSV infection in cultured and wild P. chinensis, purification and characterization of the pathogen, and the occurrence of other concomitant infection. (omitted)

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A study on object distance measurement using OpenCV-based YOLOv5

  • Kim, Hyun-Tae;Lee, Sang-Hyun
    • International Journal of Advanced Culture Technology
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    • v.9 no.3
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    • pp.298-304
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    • 2021
  • Currently, to prevent the spread of COVID-19 virus infection, gathering of more than 5 people in the same space is prohibited. The purpose of this paper is to measure the distance between objects using the Yolov5 model for processing real-time images with OpenCV in order to restrict the distance between several people in the same space. Also, Utilize Euclidean distance calculation method in DeepSORT and OpenCV to minimize occlusion. In this paper, to detect the distance between people, using the open-source COCO dataset is used for learning. The technique used here is using the YoloV5 model to measure the distance, utilizing DeepSORT and Euclidean techniques to minimize occlusion, and the method of expressing through visualization with OpenCV to measure the distance between objects is used. Because of this paper, the proposed distance measurement method showed good results for an image with perspective taken from a higher position than the object in order to calculate the distance between objects by calculating the y-axis of the image.

Modeling Exponential Growth in Population using Logistic, Gompertz and ARIMA Model: An Application on New Cases of COVID-19 in Pakistan

  • Omar, Zara;Tareen, Ahsan
    • International Journal of Computer Science & Network Security
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    • v.21 no.1
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    • pp.192-200
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    • 2021
  • In the mid of the December 2019, the virus has been started to spread from China namely Corona virus. It causes fatalities globally and WHO has been declared as pandemic in the whole world. There are different methods which can fit such types of values which obtain peak and get flattened by the time. The main aim of the paper is to find the best or nearly appropriate modeling of such data. The three different models has been deployed for the fitting of the data of Coronavirus confirmed patients in Pakistan till the date of 20th November 2020. In this paper, we have conducted analysis based on data obtained from National Institute of Health (NIH) Islamabad and produced a forecast of COVID-19 confirmed cases as well as the number of deaths and recoveries in Pakistan using the Logistic model, Gompertz model and Auto-Regressive Integrated Moving Average Model (ARIMA) model. The fitted models revealed high exponential growth in the number of confirmed cases, deaths and recoveries in Pakistan.

COVID-19 and veterinarians for one health, zoonotic- and reverse-zoonotic transmissions

  • Yoo, Han Sang;Yoo, Dongwan
    • Journal of Veterinary Science
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    • v.21 no.3
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    • pp.51.1-51.5
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    • 2020
  • A novel coronavirus emerged in human populations and spread rapidly to cause the global coronavirus disease 2019 pandemic. Although the origin of the associated virus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) remains unclear, genetic evidence suggests that bats are a reservoir host of the virus, and pangolins are a probable intermediate. SARS-CoV-2 has crossed the species barrier to infect humans and other animal species, and infected humans can facilitate reverse-zoonotic transmission to animals. Considering the rapidly changing interconnections among people, animals, and ecosystems, traditional roles of veterinarians should evolve to include transdisciplinary roles.

PAIVS: prediction of avian influenza virus subtype

  • Park, Hyeon-Chun;Shin, Juyoun;Cho, Sung-Min;Kang, Shinseok;Chung, Yeun-Jun;Jung, Seung-Hyun
    • Genomics & Informatics
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    • v.18 no.1
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    • pp.5.1-5.5
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    • 2020
  • Highly pathogenic avian influenza (HPAI) viruses have caused severe respiratory disease and death in poultry and human beings. Although most of the avian influenza viruses (AIVs) are of low pathogenicity and cause mild infections in birds, some subtypes including hemagglutinin H5 and H7 subtype cause HPAI. Therefore, sensitive and accurate subtyping of AIV is important to prepare and prevent for the spread of HPAI. Next-generation sequencing (NGS) can analyze the full-length sequence information of entire AIV genome at once, so this technology is becoming a more common in detecting AIVs and predicting subtypes. However, an analysis pipeline of NGS-based AIV sequencing data, including AIV subtyping, has not yet been established. Here, in order to support the pre-processing of NGS data and its interpretation, we developed a user-friendly tool, named prediction of avian influenza virus subtype (PAIVS). PAIVS has multiple functions that support the pre-processing of NGS data, reference-guided AIV subtyping, de novo assembly, variant calling and identifying the closest full-length sequences by BLAST, and provide the graphical summary to the end users.

Virucidal efficacy of a disinfectant solution composed of n-alkyl-dimethyl-benzyl-ammonium chloride against porcine epidemic diarrhea virus

  • Cha, Chun-Nam;Yu, Eun-Ah;Yoo, Chang-Yeul;Cho, Ki-Yung;Lee, Soo-Ung;Kim, Suk;Lee, Hu-Jang
    • Korean Journal of Veterinary Service
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    • v.37 no.2
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    • pp.105-110
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    • 2014
  • Porcine epidemic diarrhea virus (PEDV) is the causative agent of porcine epidemic diarrhea (PED) and causes a considerable economic loss in swine industry. In this study, the virucidal efficacy of the disinfectant composed to n-alkyl-dimethyl-benzyl-ammonium chloride (n-ADBAC) was investigated against PEDV. A virucidal efficacy was determined with the viability of PEDV contacted with the disinfectant in Vero cells. The disinfectant and PEDV were reacted on the hard water (HW) or organic matter suspension (OM) condition. On HW condition, PEDV was inactivated with 50 fold dilutions of the disinfectant. When the antiviral effect on OM condition was evaluated, the antiviral activity of the disinfectant showed on 10 fold dilutions against PEDV. As the disinfectant possesses the virucidal efficacy against PEDV, the disinfectant solution can be used to limit the spread of animal viral diseases.

Expression of Recombinant Rotavirus Proteins Harboring Antigenic Epitopes of the Hepatitis A Virus Polyprotein in Insect Cells

  • Than, Van Thai;Baek, In-Hyuk;Lee, Hee-Young;Kim, Jong-Bum;Shon, Dong-Hwa;Chung, In-Sik;Kim, Won-Yong
    • Biomolecules & Therapeutics
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    • v.20 no.3
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    • pp.320-325
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    • 2012
  • Rotavirus and hepatitis A virus (HAV) spread by the fecal-oral route and infections are important in public health, especially in developing countries. Here, two antigenic epitopes of the HAV polyprotein, domain 2 (D2) and domain 3 (D3), were recombined with rotavirus VP7, generating D2/VP7 and D3/VP7, cloned in a baculovirus expression system, and expressed in Spodoptera frugiperda 9 (Sf9) insect cells. All were highly expressed, with peak expression 2 days post-infection. Western blotting and ELISA revealed that two chimeric proteins were antigenic, but only D2/VP7 was immunogenic and elicited neutralizing antibody responses against rotavirus and HAV by neutralization assay, implicating D2/VP7 as a multivalent subunit-vaccine Candidate for preventing both rotavirus and HAV infections.