• Title/Summary/Keyword: virus spread

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A Digital Twin Simulation Model for Reducing Congestion of Urban Railways in Busan (부산광역시 도시철도 혼잡도 완화를 위한 디지털 트윈 시뮬레이션 모델 개발)

  • Choi, Seon Han;Choi, Piljoo;Chang, Won-Du;Lee, Jihwan
    • Journal of Korea Multimedia Society
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    • v.23 no.10
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    • pp.1270-1285
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    • 2020
  • As a representative concept of the fourth industrial revolution era where everything is digitized, digital twin means analyzing and optimizing a complex system using a simulation model synchronized with the system. In this paper, we propose a digital twin simulation model for the efficient operation of urban railways in Busan. Due to the geopolitical nature of Busan, where there are many mountains and narrow roads, the railways are more useful than other public transportation. However, this inversely results in a high level of congestion, which is an inconvenience to citizens and may be fatal to the spread of the virus, such as COVID19. Considering these characteristics, the proposed model analyzes the congestion level of the railways in Busan. The model is developed based on a mathematical formalism called discrete-event system specification and deduces the congestion level and the average waiting time of passengers depending on the train schedule. In addition, a new schedule to reduce the congestion level is derived through particle swarm optimization, which helps the efficient operation of the railways. Although the model is developed for the railways in Busan, it can also be used for railways in other cities where a high level of congestion is a problem.

Production of Specific Egg Yolk Antibodies in Chicken against Recombinant Fowl Adenovirus Fiber 2 Protein (재조합 가금 아데노바이러스 Fiber 2 단백질을 이용한 특이 난황 항체 생산)

  • Jung, Kyung Min;Lee, Seong;Kim, Jung Woo
    • Korean Journal of Poultry Science
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    • v.41 no.1
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    • pp.15-20
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    • 2014
  • Fowl adenovirus (FAV) is an important cause of several diseases, which result in considerable economic losses to the poultry farm. An outer capsid protein of FAV, fiber 2 is essential for virus growth, assembly or spread. This study was performed to produce about 22 kDa of recombinant fiber 2 protein and to immunize in laying hens to acquire the specific IgY antibody against the recombinant fiber 2. Laying hens were immunized with the recombinant fiber 2 intramuscularly in the breast muscle by injection 4 times at intervals of three weeks. At 12 weeks, serum- and egg yolk-antibody titers of hens against fiber 2 were increased up to 430,000 and 414,000, respectively. The recombinant fiber 2 could be recognized be the anti-His monoclonal antibody. Anti-fiber 2-IgY antibody could recognize the fiber 2 specifically in western blot analysis. These results suggested that the recombinant fiber 2 antigen could be used as an immunogen to elicit IgY antibody against fiber 2 and the anti-fiber 2-IgY could neutralize fowl adenovirus fiber 2 effectively.

Development of an environment-friendly moving aquatic animal rendering equipment and evaluation of fertilizer value for recycling of fish waste (친환경 이동식 수산생물 폐사체 처리장치 개발 및 재활용을 위한 비료 가치 평가)

  • Kim, Jae-Ok;Kim, Su-Mi;Seo, Jung-Soo;Jee, Bo-Young;Kim, Young-Jae;Kwon, Mun-Gyeong
    • Journal of fish pathology
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    • v.33 no.1
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    • pp.97-101
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    • 2020
  • Although aquaculture production rates grown over the years, aquatic animal diseases occur every year which causes substantial economic losses. When an aquatic animal is infected with an aquatic animal pathogen it is either incinerated or buried according to the aquatic life disease control act. Although these methods prevent the spread of disease, it is not environment friendly. Here, we developed an aquatic animal rendering equipment for disposal of fish waste which is environment-friendly and efficient. Also, fertilizer components of fish waste were evaluated value for recycling. The mobile rendering equipment was designed for field operation and/or high temperature and pressure system, oil and water separator, and shredding drying apparatus. During the experiment (July-2016 to November-2016), a total of 53,824 kg fish waste was collected, and 29,216 kg compost of rendering by-product was made. Also, compost made from viral (Viral hemorrhagic septicemia virus) infected fish did not reflect any detectable pathogen. The concentration of nitrogen, phosphorus, and organic matter in the fish waste compost were 2.17%, 26.98%, and 92.44%, respectively. The results suggest that fish waste used in this study was decomposed efficiently as per the official standard for fertilizer product. This equipment can be useful for efficient inactivation of the aquatic animal pathogenic agents and recycling of the fish waste in an environment-friendly manner.

Building a Emergency Response System for the Infectious Diseases Crisis Management (감염병 위기관리를 위한 긴급대응체계 구축)

  • Byun, Sung-Soo;Shin, Woo-Ri;Cho, Seong
    • The Journal of the Korea Contents Association
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    • v.18 no.7
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    • pp.484-494
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    • 2018
  • Middle East Respiratory Syndrome (MERS), which occurred in the Middle East in 2015, is the most acute respiratory infectious disease in Korea. The limitations of the government's ability to respond to the spread of MERS and the inadequate communication of the government to the public have reduced the public's confidence in the government's infectious disease management policy. And it became an opportunity to raise awareness that infectious diseases could easily break down the national anti-virus system. Therefore, this study investigated the emergency response system of the infectious disease in the United States and sought to improve the infection control system in Korea. In order to achieve the purpose of the study, we analyzed the government's response to the MERS in 2015, analyzed the organization structure and role of the US CDC, and IMS.

Research of video based Vibraimage technology stimulation examination KOCOSA (영상기반의 바이브라이미지 기술을 이용한 자극 검사에 대한 연구)

  • Lee, Jai-Suk;Lee, Il-ho;Lee, Tae-hyun;Choi, Jin-kwan;Chung, Suk-hwa;Han, Ji-soo
    • Convergence Security Journal
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    • v.15 no.3_1
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    • pp.41-51
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    • 2015
  • Human have more complicate and skilled ability for lying even cheat ourself. It is not easy to cheat unconscious things like sweat, eyes, or voice, but if some one cheat own self, he can cheat every of that. Lie is one of the way to spread our gene and our instinct make a lie. Every living organism even bacteria or virus use similar trick to survive. In human body, there are more complicate and profound mechanism for lying like breathe, sweat, eyes, face or voice. We can control some of that and make a fake, but it can't be perfect. Human also called 'Homo Fallax' cause we have a language and skill to lie with it. In present, we can detect lie with polygraph, but it has few weakness. So we try to use Vibraimage technology for resolve it. In this paper, we describe how to use Vibraimage for lie detection and the research history.

The outbreaks and counterplan of highly pathogenic avian influenza in Korea and overseas (국내.외 조류인플루엔자(HPAI) 발생현황과 대응방안)

  • Jang, Hyung-Kwan
    • 한국환경농학회:학술대회논문집
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    • 2009.07a
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    • pp.220-227
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    • 2009
  • For last about 10 years, the Republic of Korea experienced 3 times of outbreaks of highly pathogenic avian influenza (HPAI) from 10 December 2003 to 30 April 2004 (a total number of 19 outbreaks), 22 November 2006 to 6 March 2007 (a total number of 7 outbreaks), and 1 April 2008 to 12 May 2008 (a total number of 33 outbreaks). Among the totally 59 outbreaks, the infected premises included 35 chicken farms, 17 duck farms, 1 quail farm, and 6 farms rearing mixed species. Control measures were applied according to the HPAI standard operation procedure including depopulation of all infected and suspected flocks, movement restrictions, and disinfection of the infected farms within a 500-meter radius. Including movement restrictions, stringent control measures were additionally applied to two designated zones: the protection zone was an area within a 3-kilometer radius of the outbreak farm, and the surveillance zone was an area between a 3- to 10-kilometer radius of the outbreak farm. Farms with dangerous contacts and/or all of poultry within the protection zone was subjected to preemptive culling. Epidemiological investigations were also carried out including trace-back and trace-forward investigations to identify possible sources of spread and dangerous contact farms. Investigation teams conducted on-site examination of farm premises and facilities, interview with farm owner and staff, and review of records. Genetic and pathogenic characteristics of the virus isolates, and the results of the various surveillance activities were also analyzed. HPAI surveillance conducted in Korea includes passive surveillance of investigating notified cases, and active surveillance of testing high risk groups and areas. HPAI is a notifiable disease in Korea and all suspect cases must be reported to the veterinary authorities. Cases reported for other poultry diseases that require differential diagnosis are also tested for HPAI. Active surveillance includes annual testing of breeder duck farms, broiler duck farms and wild bird surveillance, which is concentrated during the autumn and winter. Surveillance activities conducted prior to the outbreaks have shown no evidence of HPAI infection in Korea.

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Evaluation for foot-and-mouth disease vaccines in South Korea by the test for national lot release (구제역 백신의 국가출하승인검정을 통한 품질 평가)

  • Kim, Mun-Hyeon;Seo, Min-Goo;Lee, Hyang-Sim;Kim, Ji-Yeon;Kim, Ji-Ye;Kim, Yong-Sang;Kim, Yeon-Hee
    • Korean Journal of Veterinary Service
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    • v.42 no.4
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    • pp.285-288
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    • 2019
  • Foot-and-mouth disease (FMD) causes economic problems in livestock industry because of fast spread and inducing low productivity. FMD outbreaks occurred in South Korea over the period from 2000 to 2019. Vaccination is the most practical and effective means of controlling or preventing these outbreaks, and a national vaccination policy has been in place for all FMD-susceptible animals since 2010. To prevent and control of FMD, South Korea has been using vaccines imported from the United Kingdom, Argentina, and Russia. The Animal and Plant Quarantine Agency of South Korea oversees continuous quality control of imported FMD vaccines. FMD vaccines were evaluated characteristics, sterility, pH, inactivation, safety, potency test by Korean FMD vaccine standard assay (Test for National Lot Release). The 6 company vaccines (A~F) were used Test for National Lot Release by each method. We evaluated quality of each FMD vaccine from 2015 to 2019. All batch of vaccine showed good quality control and were passed the Test for National Lot Release. The serotypes of vaccine are increasingly changing to multiple vaccine because the FMD was outbreak by various serotype virus in South Korea. Furthermore, this data may be useful as a basis for ensuring the quality of FMD vaccines and for base data to manage them. Additional study is required to simple approach for rapid evaluation of quality and antigen content identification in vaccines.

Beyond SARS-CoV-2: Lessons That African Governments Can Apply in Preparation for Possible Future Epidemics

  • Oboh, Mary Aigbiremo;Omoleke, Semeeh Akinwale;Imafidon, Christian Eseigbe;Ajibola, Olumide;Oriero, Eniyou Cheryll;Amambua-Ngwa, Alfred
    • Journal of Preventive Medicine and Public Health
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    • v.53 no.5
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    • pp.307-310
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    • 2020
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has placed unprecedented pressure on healthcare systems, even in advanced economies. While the number of cases of SARS-CoV-2 in Africa compared to other continents has so far been low, there are concerns about under-reporting, inadequate diagnostic tools, and insufficient treatment facilities. Moreover, proactiveness on the part of African governments has been under scrutiny. For instance, issues have emerged regarding the responsiveness of African countries in closing international borders to limit trans-continental transmission of the virus. Overdependence on imported products and outsourced services could have contributed to African governments' hesitation to shut down international air and seaports. In this era of emerging and re-emerging pathogens, we recommend that African nations should consider self-sufficiency in the health sector as an urgent priority, as this will not be the last outbreak to occur. In addition to the Regional Disease Surveillance Systems Enhancement fund (US$600 million) provided by the World Bank for strengthening health systems and disease surveillance, each country should further establish an epidemic emergency fund for epidemic preparedness and response. We also recommend that epidemic surveillance units should create a secure database of previous and ongoing pandemics in terms of aetiology, spread, and treatment, as well as financial management records. Strategic collection and analysis of data should also be a central focus of these units to facilitate studies of disease trends and to estimate the scale of requirements in preparation and response to any future pandemic or epidemic.

A Study for the Development of a School-based Health Education of AIDS (AIDS의 학교 보건교육 도입에 관한 연구)

  • Kim, Hyeon Suk
    • Journal of the Korean Society of School Health
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    • v.9 no.2
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    • pp.249-266
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    • 1996
  • AIDS and the spectrum of Human Immunodeficiency Virus(HIV) infections present a monumental challenge to the health of the Korean public. In response to this special challenge, I think public education and voluntary behavior changes are the most effective measures to fight the spread of the disease. Adolescents represent a critical risk group for prevention and intervention programming. Research indicates sexually active adolescents, homosexual contact, illicit drug use are an gradually increasing. These characteristically adolescent risk-taking behaviors suggest the need for schools and communities to mobilize intervention strategies. Schools are highly efficient ways to reach a majority of young people in Korea with HIV prevention programs. These programs include substantial attention to sexual and drug use behaviors with the long term objective of a multidimensional school health program. Information resulting from risk behavior surveillance activities and guidance on school health curricula is particularly useful. What is needed for adolescents is a revamping of education to give students the critical thinking and analytic skills that allow them to apply knowledge, make decisions, and think independently. The best HIV preventive education provides young people with opportunities to learn and practice just those skills. In the early stages of HIV education were focused solely on information. Providing information is easy but unfortunately, behavior change is not that simple to activate. Information must be combined with values exploration and skilly building, including responsible decision making, negotiation, refusal, and critical thinking skills. The same knowledge, attitudes and skills needed for effective HIV prevention also prevent or reduce other risks, including other sexually transmitted diseases, unwanted pregnancies, and alcohol or other drug use. The role of other youth serving organizations in HIV prevention is also important: parental and youth involvement is needed; it's important to presidential and governament leadership is essential to prevention education; promote integrated adolescent programs, to enhance health and education sector collaboration; and of course, we need to expand research on adolescent health and engage the media in health promotion. Among these changes, a school-based systematic health education of AIDS is certainly one of the essentials.

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Efficient Cell Tracking Method for Automatic Analysis of Cellular Sequences (세포동영상의 자동분석을 위한 효율적인 세포추적방법)

  • Han, Chan-Hee;Song, In-Hwan;Lee, Si-Woong
    • The Journal of the Korea Contents Association
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    • v.11 no.5
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    • pp.32-40
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    • 2011
  • The tracking and analysis of cell activities in time-lapse sequences plays an important role in understanding complex biological processes such as the spread of the tumor, an invasion of the virus, the wound recovery and the cell division. For automatic tracking of cells, the tasks such as the cell detection at each frame, the investigation of the correspondence between cells in previous and current frames, the identification of the cell division and the recognition of new cells must be performed. This paper proposes an automatic cell tracking algorithm. In the first frame, the marker of each cell is extracted using the feature vector obtained by the analysis of cellular regions, and then the watershed algorithm is applied using the extracted markers to produce the cell segmentation. In subsequent frames, the segmentation results of the previous frame are incorporated in the segmentation process for the current frame. A combined criterion of geometric and intensity property of each cell region is used for the proper association between previous and current cells to obtain correct cell tracking. Simulation results show that the proposed method improves the tracking performance compared to the tracking method in Cellprofiler (the software package for automatic analysis of bioimages).