• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2002.11a
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• pp.59-62
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• 2002

Wavelength selection and prediction algorithm for determining hematocrit are investigated. A model based on the difference in optical density induced by the pulsation of heart beat is developed by taking approximation of Twersky's theory on the assumption that the variation of blood vessel size is small during arterial pulsing[1]. A device is constructed with a five-wavelength LED array as light source. The selected wavelengths are two isobestic points and three in compensation for tissue scattering. Data are collected from 549 out-patients who are randomly grouped as calibration and prediction sets. The range of percent hematocrit was 19.3∼51.8. The ratio of the variations of optical density between systole and diastole at two different wavelengths is used as a variable. We selected several such variables that show high reproducibility among all variables. Multiple linear regression analysis is made. The relative percent error is 8% and the standard deviation is 3.67 for the calibration set. The relative % error and standard deviation of the prediction set are 8.2% and 3.69 respectively. We successfully demonstrate the possibility of non-invasive hematocrit measurement, particularly, using the wavelengths below 1000nm.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2001.05a
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• pp.119-126
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• 2001

The potential pollution problems resulting from tanker collision necessitate the requirement for an effective structural design and the development of relevant safety regulation. During a few decades, the great effort has been made by International Maritime Organization and the Administration, etc, to reduce oil spillage from collision accidents. However there is still a need for investigation in the light of structural evaluation method for the experiments and rational analysis, and design development for an operational purpose of ships. This study is aimed at investigating a complicated structural response of bow structures of oil carriers for assessing the energy dissipation and crushing mechanics of striking vessel through a methodology of the numerical analysts for the various models and its design changes. Through this study an optimal bow construction absorbing great portion of kinetic energy in the least penetration depth prior to reach to the cargo area and an effective location of collision bulkhead are investigated. In order to obtain a rational results in this study, three stages of response analysis procedures are performed as follows; 1). 16 simplified ship models are used to investigate the structural response against bow collision with variation of primary and secondary members. Mass and speed are also varied in two conditions. 2). 21 models conisted of 5 size of full scaled oil carriers are used to perform the collision simulation with the various sizes and deadweight delivered in a recent which are complied with SOLAS and MARPOL. 3). 36 models of 100k oil carrier are used to investigate the structural response and its influence to the collision bulkhead against bow collision in variation with location of collision bulkhead, primary mombers, framing system and colliding conditions, etc.

• Biotechnology and Bioprocess Engineering:BBE
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• v.6 no.2
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• pp.133-138
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• 2001

In this study, an attempt was made to increase the survival rate of bifidobacteria entrapped in alginate in the gastrointestinal tract, and to investigate the potential industrial applications, for example lyophilized capsules and yogurt. First, the protective effect of various food additives on bifidobacterial survivability was determined after exposure to simulated gastric juices and bile salts. The additives used in this study were skim milk (SM), polydextrose (PD), soy fiber (SF), yeast extract (YE), chitosan (CS), $\kappa$-carageenan ($\kappa$-C) and whey, which were added at 0.6% concentration (w/v) to 3% alginate-bifidobacterial solution. In the simulated gastric juices and bile salts, the protective effect of 0.6% skim milk-3% alginate (SM-A) beads on the survival rate of bifidobacteria proved to be higher than the other additives. Second, the hydrogen ion permeation was detected through SM-A vessel without bifidobacterial cells at different SM concentrations (0.2%, 0.4%, 0.6%, 0.8%, and 1.0%). There were no differences in terms of the pH decrease in SM-A vessels at 0.6%, 0.8%, and 1.0% (w/v) SM concentrations. The survival rate of bifidobacteria in SM-A beads would appear to be related to the SM buffering capacity against hydrogen ions and its tendency to reduce the pore size of bead. In this experiment, the survival rate of bifidobacteria entrapped in beads containing 0.6% SM showed the highest viability after exposure to simulated gastric juices for 3h, thereby indicating that 0.6% SM is the optimum concentration fir 3% alginate bead preparation. Third, the effect of SM-A beads on the freeze-drying and yogurt storage for 10 days was investigated. SM-A beads were found to be more efficient for freeze drying and yogurt storage than untrapped cells and the alginate bead. Consequently, the survival rate of bifidobacteria entrapped in SM-A beads was increased in simulated gastric juices, bile salts and probiotic products, such as lyophilized capsules and yogurt, SM-A beads can be expected to produce high value probiotic products.

• Ocean Systems Engineering
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• v.2 no.3
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• pp.217-228
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• 2012

As the size of container ships continues to increase, not many existing harbors can host the super-container ship due to its increased draft and the corresponding dredging requires huge budget. In addition, the minimization of waiting and loading/offloading time is the most important factor in harbor competitiveness. In this regard, mobile-harbor concept has been developed in Korea to achieve much improved harbor capacity and efficiency. In developing the concept, one of the most important elements is the operability of crane between two or more floating bodies in side-by-side arrangement. The container ship is to be stationed through a hawser connection to an outside-harbor fixed-pile station with the depth allowing its large draft. The mobile harbors with smart cranes are berthed to the sides of its hull for loading/offloading containers and transportation. For successful operation, the relative motions between the two or more floating bodies with hawser/fender connections have to be within allowable range. Therefore, the reliable prediction of the relative motions of the multiple floating bodies with realistic mooring system is essential to find the best hull particulars, hawser/mooring/fender arrangement, and crane/docking-station design. Time-domain multi-hull-mooring coupled dynamic analysis program is used to assess the hydrodynamic interactions among the multiple floating bodies and the global performance of the system. Both collinear and non-collinear wind-wave-current environments are applied to the system. It is found that the non-collinear case can equally be functional in dynamics view compared to the collinear case but undesirable phenomena associated with vessel responses and hawser tensions can also happen at certain conditions, so more care needs to be taken.

• Journal of Biomedical Engineering Research
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• v.19 no.5
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• pp.449-454
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• 1998

It is well known that new tissue or blood vessel is grown into a porous calcium phosphate ceramics used as a bone graft substitute due to their excellent biocompatibility. In this study, the most chemically stable porous $\beta$-crystalline form in various forms of calcium metaphosphate, Ca(PO$_3$)$_2$is prepared by the controlled thermolysis of monocalcium phosphate, Ca(H$_2$PO$_4$)$_2$.The diameter of cylindrical pores formed during cooling was controlled by a holding time at the melting point of a monocalcium phosphate and by the change of a crystallization temperature, to obtain the most appropriate size (about 200$\mu$m) of pores for the application of bone substitutes and matricuts. It was observed that the increasing holding time at the melting point of monocalcium phosphate results in the decreases of cylindrical pore sizes.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.4 no.1
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• pp.191-200
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• 2000

The marine accident is being highlighted as a serious worldwide problem for the guard station of human safety and the protection of marine environment pollution. Especially, the GMDSS is operated as a international rule for the safety of a large scale ship, but the small size ship's management is required a adaptive national rule because of the complex condition of national circumstance. This study is motivated to develop a ship's position tracking system combined with GPS information for VTS and control the ship navigation, velocity and longitude etc.. In Part of Navigation Data Transmission is GPS data transmission whih ship's ID using microprocessor and TX speed translation for flexibility with 4800∼2400 [bps]. Results show that the our system for data transmission using microprocessor is useful tool in maritime transmission as SSB used the main TX method of small ship and has a cost competitive power. Therefore, we will expected cost and technical competitive power compared to AIS. But those systems are still remained the unsolved problem for protection from marine accident.. Finally, we examined the semi-actual receiving state on simulated sailing in the around sea of Mok-Po harbor.

• Journal of Navigation and Port Research
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• v.37 no.2
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• pp.181-186
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• 2013

In a corporate financing, the decision of optimal capital structure is becoming more critical issues and still remaining a problem to be solved though many of researcher have studied. Particularly, shipping companies need a huge amount of capital finance for new vessel's capacity and then they are considering what is the best capital structure. In this point of view, this study tries to investigate the determinants of debit maturity structure focused on the Korean shipping industry. As results of panel regression analysis, firm size, liquidity, chance of growth, good cash flow are major determinants of debit expiration structure in the Korean shipping companies.

• Nuclear Engineering and Technology
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• v.45 no.3
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• pp.323-334
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• 2013

During a hypothetical core-disruptive accident (CDA) in a sodium-cooled fast reactor (SFR), degraded core materials can form roughly conically-shaped debris beds over the core-support structure and/or in the lower inlet plenum of the reactor vessel from rapid quenching and fragmentation of the core material pool. However, coolant boiling may ultimately lead to leveling of the debris bed, which is crucial to the relocation of the molten core and heat-removal capability of the debris bed. To clarify the mechanisms underlying this self-leveling behavior, a large number of experiments were performed within a variety of conditions in recent years, under the constructive collaboration between the Japan Atomic Energy Agency (JAEA) and Kyushu University (Japan). The present contribution synthesizes and gives detailed comparative analyses of those experiments. Effects of various experimental parameters that may have potential influence on the leveling process, such as boiling mode, particle size, particle density, particle shape, bubbling rate, water depth and column geometry, were investigated, thus giving a large palette of favorable data for the better understanding of CDAs, and improved verifications of computer models developed in advanced fast reactor safety analysis codes.

• Archives of Plastic Surgery
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• v.34 no.2
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• pp.203-208
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• 2007

Purpose: Myocutaneous flap was widely used for trochanteric pressure sore but it had many drawbacks such as donor site morbidity, dog-ear deformity and functional muscle sacrifice. We have performed fasciocutaneous flap based on perforating vessels and succeeded in overcoming its drawbacks. Methods: We experienced 11 cases of perforator-based fasciocutaneous flap for the coverage of trochanteric pressure sore in 9 patients, 2 cases of which were bilateral. The ambulatory status of patient group is as follows: 6 of them used a wheelchair, 2 of them are free walking, 1 of them use a wheelchair or crutches. Flap was supplied by cutaneous perforating vessel of descending branch of the lateral circumflex femoral artery and the third perforating artery of the deep femoral artery. The size of wounds were from $4{\times}6.5cm$ to $10{\times}13cm$. Results: We did not find any flap loss or congestion except 2 partial wound dehiscences and 1 wound infection. Donor site morbidity was not found. We observed no recurrence of the pressure sore during the 2.5 year follow-up period. Conclusion: We considered that perforator-based fasciocutaneous flap could overcome the traditional drawbacks of the conventional myocutaneous flap and its modified flap for trochanteric pressure sore. And this flap has many advantages for covering trochanteric pressure sore without any donor site deformity and morbidity, which would greatly improve the aesthetic result.

• Korean Journal of Poultry Science
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• v.42 no.3
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• pp.239-245
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• 2015

Transgenic animals have been widely used for developmental biology studies, as disease models, and even in industry such as transgenic bioreactor animals. For transgenic birds, quail has the great advantages of small body size, short generation time, and frequent egg production. To date, retroviral or lentiviral transduction has been used to generate transgenic quail for various purposes. However, the efficiency of transgenic offspring production with these methods is relatively low and viral vector usage has safety issues. Unfortunately, non-viral transgenesis has not been established in quail due to a deficiency of stem cell and germ cell culture systems. In this study, we established a direct in ovo lipofection method that could be used to create transgenic quail without germline-competent cells or viruses. To optimize the injection stage during embryo development, the liposome complex (containing piggyBacCMV-GFP and transposase plasmids) was introduced into an embryonic blood vessel at 50 hr, 55 hr or 60 hr. GFP expression was detected in various tissues (heart, kidney, liver and stomach) on day 12 of incubation under a fluorescence microscope. Additionally, GFP-positive cells were detected in the recipient embryonic gonads. In conclusion, the direct in ovo lipofection method with the piggyBac transposon could be an efficient and useful tool for generating transgenic quail.