• Title/Summary/Keyword: variance component

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Effect of remimazolam and propofol anesthesia on autonomic nerve activities during Le Fort I osteotomy under general anesthesia: blinded randomized clinical trial

  • Yuto Tsuji;Kyotaro Koshika;Tatsuya Ichinohe
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.24 no.4
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    • pp.273-283
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    • 2024
  • Background: This study evaluated the effect of remimazolam and propofol on changes in autonomic nerve activity caused by surgical stimulation during orthognathic surgery, using power spectrum analysis of blood pressure variability (BPV) and heart rate variability (HRV), and their respective associations with cardiovascular fluctuations. Methods: A total of 34 patients undergoing Le Fort I osteotomy were randomized to the remimazolam (Group R, 17 cases) or propofol (Group P, 17 cases) groups. Observables included the low-frequency component of BPV (BPV LF; index of vasomotor sympathetic nerve activity), high-frequency component of HRV (HRV HF; index of parasympathetic nerve activity), balance index of the low- and high-frequency components of HRV (HRV LF/HF; index of sympathetic nerve activity), heart rate (HR), and systolic blood pressure (SBP). Four observations were made: (1) baseline, (2) immediately before down-fracture, (3) down-fracture, and (4) 5 min after down-fracture. Data from each observation period were compared using a two-way analysis of variance with a mixed model. A Bonferroni multiple comparison test was performed in the absence of any interaction. One-way analysis of variance followed by Tukey's multiple comparisons test was performed when a significant interaction was observed between time and group, with P < 0.05 indicating statistical significance. Results: Evaluation of autonomic nerve activity in comparison with baseline during down-fracture showed a significant increase in BPV LF (P < 0.001), an increasing trend in HRV LF/HF in Group P, and an increasing trend in HRV HF in Group R. There were no significant differences in HR or SBP between the two groups. Conclusion: During down-fracture of Le Fort I osteotomy, sympathetic nerve activity was predominant with propofol anesthesia, and parasympathetic nerve activity was predominant with remimazolam anesthesia.

Constructing a Questionnaire on Male Workers' Sobriety Behavior - Based on Ajzen's Theory of Planned Behavior - (남성 직장인의 절주행위 측정도구 개발 -Ajzen의 계획적 행위 이론 적용-)

  • Park, In-Hyae;Kim, Youn-Kyoung
    • Research in Community and Public Health Nursing
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    • v.21 no.2
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    • pp.156-168
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    • 2010
  • Purpose: The purpose of this study was to construct a questionnaire to assess male workers' sobriety behavior based on Ajzen's Theory of Planned Behavior (TPB). Methods: A primary questionnaire with 56 questions was constructed based on literature review and structured interview with male workers. The Content Validity Index (CVI) was evaluated by a group of experts, construct validity was tested by principle component analysis, and reliability was evaluated by Cronbach's ${\alpha}$ and the test-retest reliability test. Results: Fifty two questions showed higher than .8 of CVI. Four factors explained 78.71% of the total variance among items for sobriety intention and direct measure, and six factors explained 67.99% of the total variance among indirect measure items and those factors coincided with the variables of TPB in factor analysis. Cronbach's ${\alpha}$ of this questionnaire was .873 and the result of test-retest reliabilty test was relatively reliable. A total of 41 items with 7-point scale were constructed in the final version. Conclusion: This questionnaire was valid and reliable to measure sobriety behavior based on TPB in male workers. It can be useful to evaluate the result of a sobriety program for male workers.

Physicochemical Properties and Sensory Evaluation for the Heat Level (Hot Taste) of Korean Red Pepper Powder

  • Ku, Kyung-Hyung;Lee, Kyung-A;Park, Jae-Bok
    • Preventive Nutrition and Food Science
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    • v.17 no.1
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    • pp.29-35
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    • 2012
  • This study investigated the heat level rating of several varieties of Korean red peppers. The chemical constitution of Korean red pepper samples were as follows: 0.54~290.15 mg% capsaicinoids, 79.22~139.09 ASTA value, and 16.76~29.92% free sugar content. The heat level of the Korean red pepper samples was evaluated by trained panelists and the correlation coefficient and F value (0.001%) of the panelist’s results were determined to be significant. In the principle component analysis (PCA), PC1 (capsaicinoids) and PC2 (free sugar) were shown to represent 31.98% and 25.77% of the total variance, respectively. The results of panelists trained for red pepper heat rating were evaluated using analysis of variance and correlation analysis. The trained panelists showed a high F value (p=0.05) and high correlation coefficient. A high correlation efficient of 0.84~0.93 for the test samples with a 40 Scoville heat unit (32,000 SHU red pepper powder) was reported in the sensory evaluation of the Korean red pepper heat level by a trained panel. However, the panel showed a low correlation efficiency of 0.70 $R^2$ when the 60 SHU test samples were included in the analysis.

A Study of Gage R&R Analysis Considering the Variations of Between-Within Group and Within Part (군간-군내-부품내 변동을 고려한 Gage R&R 분석에 관한 연구)

  • Lee, Seung-Hun;Lee, Chang-U
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2005.05a
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    • pp.975-982
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    • 2005
  • The purpose of the Gage R&R study is to determine whether a measurement system is adequate for monitoring a process. If the measurement system variation is small relative to the process variation, then the measurement system is deemed 'adequate'. The sources of variation associated with the measurement system are compared using an analysis of variance (ANOVA) model, in general. A typical ANOVA model used in a standard Gage R&R study is the two-factor random effect model. Then, the ANOVA partitions the total variation into three categories: repeatability, reproducibility, part variation. However, if the process variation possesses the between group variation, within group variation, and within-part variation, these variations can cause the measurement system evaluation to provide misleading results. That is, in the standard Gage R&R study these variations affect the estimate of repeatability, reproducibility, or both. This paper presents a four-factor nested factorial ANOVA model which explicitly considers these variations for the Gage R&R study. The variance component estimates are derived by setting the EMS equations equal to the corresponding mean square from the ANOVA table and solving. And the proposed model is compared with the standard Gage R&R model.

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A Study of Gage R&R Analysis Considering the Variations of Between-Within Group and Within Part (군간-군내-부품내 변동을 고려한 Gage R&R 분석에 관한 연구)

  • Lee, Seung-Hoon;Lee, Chang-Woo
    • IE interfaces
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    • v.18 no.4
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    • pp.444-453
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    • 2005
  • The purpose of the Gage R&R study is to determine whether a measurement system is adequate for monitoring a process. If the measurement system variation is small relative to the process variation, then the measurement system is deemed "adequate". The sources of variation associated with the measurement system are compared using an analysis of variance (ANOVA) model, in general. A typical ANOVA model used in a standard Gage R&R study is the two-factor random effect model. Then, the ANOVA partitions the total variation into three categories: repeatability, reproducibility, part variation. However, if the process variation possesses the between group variation, within group variation, and within part variation, these variations can cause the measurement system evaluation to provide misleading results. That is, in the standard Gage R&R study these variations affect the estimate of repeatability, reproducibility, or both. This paper presents a four-factor nested factorial ANOVA model which explicitly considers these variations for the Gage R&R study. The variance component estimators are derived by setting the EMS equations equal to the corresponding mean square from the ANOVA table and solving. And the proposed model is compared with the standard Gage R&R model.

An Analysis of Genetic Variation and Divergence on Silk Fibre Characteristics of Multivoltine Silkworm (Bombyx mori L.) Genotypes

  • Kumaresan P.;Koundinya P. R.;Hiremath S. A.;Sinha R. K.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.14 no.1
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    • pp.23-32
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    • 2007
  • The nature of genetic variation and diversity among the 65 multivoltine silkworm genotypes was evaluated for 16 post cocoon characters. The components of genetic variation revealed higher PCV (60.487%) and GCV (44.56%) for evenness (variation 1) followed by cohesion (PCV=55.38%, GCV=40.36%) and non-broken filament length (PCV=32.05%, GCV=31.28%). The higher heritability ($h^2$ in broad sense) was observed for boil-off loss (95.6%) followed by non-broken filament length (95.22%). The both genotypic and phenotypic correlation indicated significant positive correlation of filament length with non-broken filament length, silk recovery, raw silk, neatness, and low neatness; and negative correlation with denier, renditta and silk waste. The principal component analysis (PCA) revealed 75.381 % of total variance from the five principal components extracted. On the basis of Mahalonobis' $D^2$ values (Ward's minimum variance), the sixty-five multivoltine silkworm genotypes were classified in to 9 clusters with substantial inter and intra cluster distances. Number of genotypes included in different clusters varied from 3 to 17. The results indicated that the optimum distance obtained in cluster VII (15.059) along with higher cluster mean values especially for filament length, non broken filament length, renditta, silk recovery, silk waste, and raw silk emphasized the utilization of these genotypes in the conventional silkworm breeding programme for improvement of multivoltine silk fibre quality. The possibility of exploiting genetic variation in post cocoon traits for efficient breeding programme is discussed.

A Study on the Condition Monitoring for GIS Using SVD in an Attractor of Chaos Theory

  • J.S. Kang;Kim, C.H.;R.K. Aggarwal
    • KIEE International Transactions on Power Engineering
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    • v.4A no.1
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    • pp.33-41
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    • 2004
  • Knowledge of partial discharge (PD) is important to accurately diagnose and predict the condition of insulation. The PD phenomenon is highly complex and seems to be random in its occurrence. This paper indicates the possible use of chaos theory for the recognition and distinction concerning PD signals. Chaos refers to a state where the predictive abilities of a systems future are lost and the system is rendered aperiodic. The analysis of PD using deterministic chaos comprises of the study of the basic system dynamics of the PD phenomenon. This involves the construction of the PD attractor in state space. The simulation results show that the variance of an orthogonal axis in an attractor of chaos theory increases according to the magnitude and the number of PDs. However, it is difficult to clearly identify the characteristics of the PDs. Thus, we calculated the magnitude on an orthogonal axis in an attractor using singular value decomposition (SVD) and principal component analysis (PCA) to extract the numerical characteristics. In this paper, we proposed the condition monitoring method for gas insulated switchgear (GIS) using SVD for efficient calculation of the variance. Thousands of simulations have proven the accuracy and effectiveness of the proposed algorithm.

Estimation of Genetic Variance and Covariance Components for Litter Size and Litter Weight in Danish Landrace Swine Using a Multivariate Mixed Model

  • Wang, C.D.;Lee, C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.7
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    • pp.1015-1018
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    • 1999
  • Single trait mixed models have been dominantly utilized for genetic evaluation of the reproductive traits in swine. However employing multiple trait approach may lead to more accurate genetic evaluations. For 5 litter size and litter weight traits of Danish Landrace, genetic parameters were estimated with a multiple trait mixed model. The heritability estimates were 0.02, 0.03, 0.03, 0.05, and 0.07, respectively for litter size at birth, litter size born alive, litter weight at birth, litter size at weaning, and litter weight at weaning. Negative genetic correlations were all positive. The litter weight at birth showed genetic antagonism with litter size born alive (-0.65) and litter size at weaning (-0.31), but positive with litter size at birth (0.47) and litter weight at weaning (0.31). The estimates of environmental correlations were larger than their corresponding genetic correlation estimates except for those between litter weight at birth and the other four traits. This study recommends simultaneous selection for two or more traits with multivariate mixed models in order to improve overall economic response.

Estimation of Crossbreeding Parameters for Serum Lysozyme Level in Broiler

  • Nath, M.;Singh, B.P.;Saxena, V.K.;Dev Roy, A.K.;Singh, R.V.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.2
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    • pp.166-171
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    • 2002
  • The main objective of the present study is to estimate the crossbreeding parameters in respect to serum lysozyme level in broilers. The experiment involved a complete $4{\times}4$ diallel design using four synthetic broiler lines namely Coloured Synthetic Male Line (CSML), White Synthetic Male Line (WSML), Coloured Synthetic Female Line (CSFL) and Naked Neck Line (NNL). The lyophilised Micrococcus lysodeikticus suspension was used to detect the lysozyme level in the serum of birds. The data were analysed by least-squares method to find the effects of genetic and non-genetic factors using appropriate model. The crossbreeding parameters for this trait were estimated by complete diallel model assuming the effect of each synthetic line as fixed. The results indicated that additive and non-additive genetic variation attributed to minor genes at many loci is important for the genetic control of serum lysozyme level in chickens. Total non-additive components of variance also showed significant amount of heterosis in crossbred progenies, and therefore exploitation of non-additive component of variance is possible for improvement in serum lysozyme level in broilers. The overall results suggested that for commercial broiler production system, the selection for specialised line on the basis of serum lysozyme level and subsequent crossing of parent lines could enhance the immunocompetence status in relation to serum lysozyme level in crossbred chickens.

Validation of Quality of Life Index-Cancer among Korean Patients with Cancer (Quality of Life Index-Caner의 구성타당도 검증 -국내 암환자를 대상으로-)

  • 소향숙;이원희;이은현;정복례;허혜경;강은실
    • Journal of Korean Academy of Nursing
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    • v.34 no.5
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    • pp.693-701
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    • 2004
  • Purpose: The purpose of this study was to validate Quality of Life Index-Cancer (Q.L.I.-C) developed by Ferrans (1990) among Korean cancer patients. Method: This study design was exploratory factor analysis methodology. Q.L.I.-C was translated into Korean and reverse-translated into English. The subjects were 357 Korean patients with various cancers. Data were collected by questionnaires from May to August, 2000 and was analyzed by descriptive statistics, Principal Component Analysis for construct validity and Cronbach's alpha coefficient for reliability. Result: The range of factor loadings was .446~.841. The explained variance from the 5 extracted factors was 63.7% of the total variance. The first factor 'family' was 35.5%, and 'health & physical functioning', 'psychological', 'spiritual', and 'economic' factors were 11.5%, 6.9%, 5.6%, and 4.2% respectively. Because of cultural difference between Americans and Koreans, certain items such as sexuality, job status, and education were deleted from the extraction of factors in this study. The Cronbach's alpha coefficient was .9253 among the 28 items. Conclusion: Q.L.I.-C could be applied in measuring quality of life of Korean cancer patients. It also recommend to do further studiesfor validation of Q.L.I.-C American and Korean versions relating to cultural differences.