• Title/Summary/Keyword: use potential

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The Construction of Semi-diabatic Potential Energy Surfaces of Excited States for Use in Excited State AIMD Studies by the Equation-of-Motion Coupled-Cluster Method

  • Baeck, Kyoung-Koo;Martinez, Todd J.
    • Bulletin of the Korean Chemical Society
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    • v.24 no.6
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    • pp.712-716
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    • 2003
  • The semi-diabatic potential energy surfaces (PESs) of the excited states of polyatomic molecules can be constructed for use in ab initio molecular dynamics (AIMD) studies by relying on the continuity of the electronic energy, oscillator strength, and spherical extent of an excited state along with first derivatives of these quantities as computed by using the equation-of-motion coupled-cluster (EOM-CC) method. The semidiabatic PESs of both the π → $π^*$ valence excited state and the 3s-type Rydberg state of ethylene are presented and discussed in this paper, in conjunction with some of the AIMD results we obtained for these states.

The Activity and Utilization of Urease Inhibitors (요소분해효소 억제물질의 작용과 응용에 관한 연구)

  • 주영규
    • Asian Journal of Turfgrass Science
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    • v.6 no.1
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    • pp.23-28
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    • 1992
  • Urea, the major N source of world agriculture involves a serious urea-N loss through NH$_3$volatilization. Approaches to decrease N loss include using urease inhibitors in view of the environmental protection and the increase of urea-N efficiency. The purpose of laboratory researches was toassess the potential value of urease inhibitors to increase urea-N efficiency in soil and Kentucky blue-grass(Poa Pratensis L.) turf. The activity of urease inhibitors Phenyiphosphorodiamjdate(ppD) and N-(n-butyl) thiophosphoric triamjde(NBPT) measured to break-down ammonia volatilization. The soil and turf used in this project were from the fairway in one of the Korean gof course. The researches were carried out for two weeks to measure the urease activities on urea hydrolysis under four temperatures (10~ 40$^{\circ}C$) and for one week on turfgrass using forced-draft system. Results indicated that Urea-N involves considerable loss through gaseous NH$_3$ by urease activities in plant-soil systems. Urease inhibitors PPD and NBPT have potential value for increasing N use efficiency by reduing NH$_3$ volatilization. NBPT deserves futher evaluation as fertilizer amendment than PPD use of urea in turf industries.

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Are Beta Blockers New Potential Anticancer Agents?

  • Akbar, Shahid;Alsharidah, Mansour Saleh
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9567-9574
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    • 2014
  • ${\beta}$-Blockers have been one of the most widely used and versatile drugs for the past half a century. A new potential for their use as anti-cancer drugs has emerged in the past few years. Various retrospective case control studies have been suggestive that use of ${\beta}$-blockers before the diagnosis of cancer could have preventive and protective effects against non-small cell lung carcinoma, melanoma, and breast, pancreatic and prostate cancers. Experimental and clinical observations are still inconclusive with some inconsistent findings. However, indications are pointing toward a positive role of some ${\beta}$-blockers against certain forms of cancers. This mini review is an effort to present the up to date published results of case-control studies and experimental findings.

The Practical Use of the Productive Aquifer Systems as a Source of a Renewable Thermal Energy and Local Water Works (지방상수도의 신규 수원과 재생에너지원으로서 고산출성 대수층의 활용)

  • Hahn, Jeongsang
    • Journal of Soil and Groundwater Environment
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    • v.23 no.4
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    • pp.16-25
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    • 2018
  • The Quaternary volcanic rocks, clastic sedimentary rocks of Kyongsang System, and carbonate rocks of Joseon and Pyongan System are known as good productive and potential aquifer systems in South Korea. National Groundwater Informaton Mangement and Service System (GIMS) indicates that the exploitable, sustainable, and current use of groundwater are about 18.8, 12.9, and $3.73billion\;m^3/a$, respectively. The rest amount ($9.1billion\;m^3/a$) can still be used for an additional water supply source. Therefore. comprehensive groundwater survey work comprising hydrogeological mapping, subsurface investigation and quantitative aquifer test etc. are highly required to establish rational groundwater management strategy.

Finite Element Analysis of 2-D Magnetostatic Problem using Magnetic flux density as an unknown variable (자속밀도를 미지변수로 한 2차원 정자장 유한요소 해석)

  • Chang, Woo-Sok;Hahn, Song-Yop
    • Proceedings of the KIEE Conference
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    • 1989.11a
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    • pp.37-40
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    • 1989
  • When we analyze the magnetostatic problem by the FEM, it is a traditional method to use the magnetic vector potential as an unknown variable.(abbreviated to A Method) Therefore, we should differentiate this magnetic vector potential to get the magnetic flux density. In this procedure of differentiation, the accuracy of the calculation is reduced. In order to overcome this problem, this paper uses the magnetic flux density as an unknown variable.(abbreviated to B Method) The validity of this new method (B Method) to use the magnetic flux density directly as an unknown variable, is ensured as the result of the application example researches.

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Beta-spectra for the Radionuclides in Medicine

  • Yi, Chul-Young;Kim, Kyung-Hwa;Park, Kyung-Bae;Han, Hyon-Soo;Jun, Jae-Shik;Chai, Ha-Seok
    • Progress in Medical Physics
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    • v.9 no.1
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    • pp.37-46
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    • 1998
  • Beta-particle energy distributions of the radionuclides in medicine are calculated for the medical physics applications. The radial component solutions of Dirac wave equations are evaluated for a point-nucleus un screened Coulomb potential. The WKB method is employed to correct the screening due to the orbital-electron cloud. Fierz interference terms are ignored. The radionuclides considered are $\^$32/P, $\^$90/Y, $\^$131/I, $\^$166/Ho, $\^$192/Ir, $\^$198/Au, $\^$153/Sm, $\^$169/Er and $\^$188/Re. A total of 9 beta-spectra for the radionuclides, currently in domestic use or potential use in the near future, are calculated with enough accuracy and presented in graphs and tables.

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Fiber-Reinforcements of Composite Restorations

  • Cho, Kyung-Mo
    • Proceedings of the KACD Conference
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    • 2001.05a
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    • pp.258-258
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    • 2001
  • Fiber-reinforced materials have highly favorable mechanical properties. and their strength-to-weight ratios are superior to those of most alloys. When compared to metals they offer many other advantages as well. including non-corrosiveness. translucency. good bonding properties. and ease ofrepair. Fiber-reinforced materials can be categorized to pre-impregnated. impregnation required. dental laboratory products. chairside products and prefabricated posts. so it is not suprising that fiber-reinforced composites have potential for use in many applications in dentistry. Fiber-reinforced materials can be utilized in frameworks for crowns. anterior or posterior fixed prostheses. chairs ide tooth replacements. periodontal splints. customized posts. prefabricated posts. orthodontic retention. denture reinforcements and in implants dentistry. To realize the full potential of using fiber-reinforced composite restorations. it is essential that the clinician and laboratory technician understand concepts of tooth preparation and framework design. Also practitioner may appreciate the background information and other details about the materials themselves so that identify the rationale for their use in various clinical situations. select well-suited materials. and carry out related procedures. Understanding the material properties and take many attentions. fiber-reinforced materials will give more esthetic. more easy. more strong and more reliable restorations.ations.

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A Study on Using Possibility of Talc Powder as Concrete Admixture (활석 미분말의 콘크리트용 혼화재료로써 활용가능성에 관한 연구)

  • Woo, Jong-Kwon;Ryu, Hyun-Gi
    • Journal of the Korea Institute of Building Construction
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    • v.6 no.4 s.22
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    • pp.93-98
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    • 2006
  • Admixture materials are used in mixing concrete or mortar to improve quality and performance of the concrete. This study examines the potential use of talc as a substitute for cement, the benefits of recycling waste resources for economical efficiency and quality improvement of concrete. The test was carried out by replacing the plain mix with fine grains of talc at the rate of 10%, 20%, and 30%. Talc was divided into three groups depending on the degree of pulverizing. For wet concrete, porosity, slump, bleeding per unit, and setting time by penetration resistance were measured; similarly, for dry concrete, strength and watertight Property were tested. Test results showed that the amount of bleeding and setting time could be shortened, but the strength and watertight proofing severely deteriorated. However, at the replacement rate of 10%, talc showed equal performance with the plain at all degrees of pulverization, which suggests its potential use as admixture material.

The Association between Serotonin Reuptake Inhibitors and Obstructive Sleep Apnea in People with Epilepsy-A Retrospective Analysis

  • Cheng, Jocelyn Y.
    • Journal of Sleep Medicine
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    • v.15 no.2
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    • pp.43-47
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    • 2018
  • Objectives: Obstructive sleep apnea (OSA) is common in people with epilepsy (PWE), and confers medical and seizure-related consequences when untreated. Positive airway pressure, the gold-standard for OSA management, is limited by tolerability. As serotonin is involved respiratory control and amelioration of seizure-induced respiratory events, this study aims to determine whether serotonin reuptake inhibitors (SRIs) may represent a potential therapeutic option. Methods: A retrospective study of 100 PWE and OSA ${\geq}18$ years of age was conducted. The primary outcome measure was OSA severity as function of SRI use, with rapid eye movement (REM)-related OSA as a secondary outcome. Results: Older age and depression were more common in those taking an SRI. There was no association between SRIs and OSA severity. However, the SRI group was less likely to have REM-related OSA. Conclusions: In PWE and OSA, SRI use is associated with reduced risk of REM-related OSA, and may represent a potential management strategy.

Optogenetic neuromodulation with gamma oscillation as a new strategy for Alzheimer disease: a narrative review

  • Ko, Haneol;Yoon, Sang-Pil
    • Journal of Yeungnam Medical Science
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    • v.39 no.4
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    • pp.269-277
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    • 2022
  • The amyloid hypothesis has been considered a major explanation of the pathogenesis of Alzheimer disease. However, failure of phase III clinical trials with anti-amyloid-beta monoclonal antibodies reveals the need for other therapeutic approaches to treat Alzheimer disease. Compared to its relatively short history, optogenetics has developed considerably. The expression of microbial opsins in cells using genetic engineering allows specific control of cell signals or molecules. The application of optogenetics to Alzheimer disease research or clinical approaches is increasing. When applied with gamma entrainment, optogenetic neuromodulation can improve Alzheimer disease symptoms. Although safety problems exist with optogenetics such as the use of viral vectors, this technique has great potential for use in Alzheimer disease. In this paper, we review the historical applications of optogenetic neuromodulation with gamma entrainment to investigate the mechanisms involved in Alzheimer disease and potential therapeutic strategies.