• Archives of Reconstructive Microsurgery
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• 제12권1호
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• pp.13-18
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• 2003

Fournier's gangrene is a synergistic necrotizing fasciitis of the perineal, perirectal and urogenital area and can be fatal unless treated in early stage. Perianal and urogenital infections are common causes of the disease but it can occur after artificial procedure on perineal area using by surgical instruments. It is mixed aerobic and anaerobic infection and E. coli is the most common causative bacteria. Untill now many investigators have focused on early diagnosis, preserving hemodynamic stability, broad-spectrum systemic antibiotics and treatment of underlying disease in management of Fournier's gangrene. The authors have experienced five patients of chronic liver disease whose necrotizing perineal infections developed spontaneously and treated them aggressively as described above and reconstructed perineal soft tissue defects using by various surgical methods, then we got good results both functionary and cosmetically. From now on, we would better reconstruct soft tissue defect of perineum with skin graft or pedicled flap in early stage when treat Fournier's gangrene, thereafter we can get an ultimate increase in patient's life quality.

• 대한영상의학회지
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• 제81권5호
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• pp.1083-1095
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• 2020

2019년 비뇨생식기 초음파와 MRI의 보험급여 범위가 확대되어 보다 많은 환자들이 급여로 영상검사를 받을 수 있게 되었다. 비뇨기계 초음파와 MRI는 암 환자 등 중증질환 환자에서 는 기존에도 급여 혜택을 받을 수 있었으나 이번 급여 범위 확대로 초음파의 경우 대부분의 질환, MRI의 경우에도 조직검사 전 전립선암이나 난소암 의증, 자궁근종절제술 시행 전 자궁 MRI, 각종 선천 기형 등 양성질환에서도 급여로 검사가 가능해졌다. 그러나 급여화로 인해 각 검사 별 적응증과 추적검사 가능 질환 및 횟수 등이 복잡해지고 획득하여야 할 표준영상과 언급하여야 하는 판독소견서의 양식이 정해져 있어 검사를 처방하고 시행하는 의사들이 주의해야 할 사항들이 생겼다. 건강보험 적용 기준에 대한 충분한 이해를 통한 진료는 환자들의 진료 결과를 증진시키는 데 도움이 될 것이다.

• 사상체질의학회지
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• 제15권3호
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• pp.118-123
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• 2003

The climacteric is the period of passage out of the reproductive stage of life and into the nonreproductive phase. The climacteric can be accompanied by wide-ranging, uncomfortable and disruptive symptoms. Symptoms that are related to hormonal changes include abnormal bleeding, facial flushing, and urogenital discomfort. This patient was 45- year-old woman who had headache, facial flushing, thirst, fatigue, irregular menstruation, urogenital discomfort and had been diagnosed and teated climacteric. We classified this patient as Soyangin(少陽人) Yin collapsed ease(亡陰證) and prescribed Hyeongbangsabaeksan(荊防瀉白散). We experienced the good effect of Hyeongbangsabaeksan on Soyangin Mangyin-disease We report the healing process and the result of treatment in this study.

• Journal of Chest Surgery
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• 제37권3호
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• pp.279-281
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• 2004

베체트병은 구강 생식기의 궤양, 안구와 피부 병변을 주 증상으로하고 심혈관계, 호흡기계, 소화기계, 중추신경계, 비뇨기계를 침범하여 다양한 증상을 나타낼 수 있다. 베체트병에서 경동맥류와 장천공의 동반은 드문 경우로, 병리소견과 병력상 베체트병으로 진단 받은 환자에서 상기 병증에 대한 수술을 시행하였기에 보고하는 바이다.

• Journal of Medicine and Life Science
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• 제18권2호
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• pp.35-39
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• 2021

Exaggerated acute and late toxicities following radiotherapy have been reported in patients with pre-existing connective tissue diseases, such as systemic lupus and scleroderma. Behcet's disease (BD) is a relapsing multisystem connective tissue disease characterized by vasculitis in the mucocutaneous, ocular, gastrointestinal, respiratory, neurologic, urogenital, articular, and cardiovascular systems. Data concerning the relationship between radiotherapy toxicity and BD are limited in the literature. Here, we report a case of lung cancer treated with radiotherapy (60 Gy) in a patient with BD. No severe radiation-induced toxicity was observed. Radiation-induced toxicity in patients with BD has also been discussed.

• 사상체질의학회지
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• 제23권1호
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• pp.87-97
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• 2011

1. Objectives: We aimed to derive using status of Sasang Constitutional herbal prescription and good effective one in specific disease. 2. Methods: We sent Questionnaire to 463 oriental medical doctor listed Korea Sasang Constitutional medicine from 2009 years. 10 to 11 and got back 191 questionnaire, which consisted of sex, age, clinical duration, working type, using status and effectiveness of Sasang Constitutional herbal prescription. 3. Results: - Digestive tract disease was especially most effective field, and circulatory, the endocrine, dermatology, psychopathy, urogenital disease went in order in western disease. - Spleen disease was especially most effective field, and the heart and circulatory, neuropsychiatry, lung, liver, psychopathy, gynecology disease went in order in oriental medicine pathology. - Chungshimyenja-tang was effective to neuropsychiatry and heart disease in Taeeumin, Hyangsayangwi-tang to disease related digestive system, Palmulgunja-tang to gynecology disease in Soeumin, Dockhalgiwhang-tang to diet disorder, Yanggeuksanwha-tang to heart and psychologic disease in Soyangin. 4. Conclusions: Constitutional prescription effected on special pathological symptom support weaken organ, and these result will help to make treatment standard and support clinical study of constitutional medicine.

• 정신신체의학
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• 제4권1호
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• pp.98-108
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• 1996

Korean women are now living almost 1/3 of their life after menopause. Sex-steroid hormone deficiency adversely affect various fields of physical & mental activity and quality of life during this period. Therefore, replacement of deficient hormone is thought to be natural therapeutic modality. Postmenopausal syndrome is recently redefined as an endocrinopathy with both short-and long-term sequelae, as a result of cessation of ovarian function. Hormone replacement therapy taken at or near time of menopause alleviates shot-term acute menopausal symptoms such as vasomotor disturbances and psychological problems. HRT also beneficially affects some of intermediate symptoms such as urogenital atrophy and cutaneous problems. The major benefits of long-term use were reductions in risk of long-term sequelae, that is, total fracture by 50-60%, cardiovascular disease by 50% and cerebrovascular disease by 30-40%, respectively. In addition, HRT may also positively influence Alzheimer's disease, reduce the colorectal cancer risk and increase longevity of the life. In conclusion, all postmenopausal women should consider preventive HRT when there are no contraindications.

• 한국임상수의학회지
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• 제1권1호
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• pp.33-40
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• 1984

The number of dairy cows diagnosed and treated at Hyup-dong Animal Hospital from July 1983 to June 1984 was amounted to 3,073 heads of Holstein breed and the result of analysis of diseases was as follows : 1. In the topographic diagnostic categories, 41.23% of all cases involved the urogenital system and were observed most prominent. Next were digestive system (22.10%), general and regional (14.55 %), respiratory system (8.20%) and musculoskeletal system (7.06%) in decreasing order. 2. In urogenital system 50.20% of all diagnosis involved metritis and this were most prominent disease. Next were repeat breeder(15.31%), retained placenta (12.79%) and ovary disfunction(9.40 %) in decreasing order. 3. In digestive system 36.82% of all diagnosis involved enteritis and were most prominent. Next were abomasal displacement (29.31%), lumen indigestion (20.32%) and lumen bloat (9.57%) in decreasing order 4. In general and regional diseases, 52.80% of all diagnosis involved ketosis and were most prominent. Next were milk fever (25.50%), downer cow (5.82%) and omphalitis (4.47%) in decreasing order. 5. In respiratory system, 82.54% of all diagnosis involved upper respiratory tract infections and were most prominent. Next were pneumonia (15.87%). 6. In musculoskeletal system, 49.31% of all diagnosis involved foot rot and were most prominent. 7. In milk secreting system, 61.64% of all diagnosis involved mastitis and ere most prominent. Next were stenosis of teat canal (16.35%). 8. Among the individual disease entities, endometritis marked 20.7%, enteritis 8.13%, ketosis 7.68% upper respiratory tract infection 6.77%, repeat bheeder 6.31%, retained placenta 5.27%, abomasal displacement 4.69%, and lumen impaction 4.49%, respectively of total 3,073 cases in decreasing order.

• The Korean Journal of Physiology and Pharmacology
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• 제19권3호
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• pp.257-262
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• 2015

It is well known that cigarette smoke can cause erectile dysfunction by affecting the penile vascular system. However, the exact effects of nicotine on the corpus cavernosum remains poorly understood. Nicotine has been reported to cause relaxation of the corpus cavernosum; it has also been reported to cause both contraction and relaxation. Therefore, high concentrations of nicotine were studied in strips from the rabbit corpus cavernosum to better understand its effects. The proximal penile corpus cavernosal strips from male rabbits weighing approximately 4 kg were used in organ bath studies. Nicotine in high concentrations ($10^{-5}{\sim}10^{-4}M$) produced dose-dependent contractions of the corpus cavernosal strips. The incubation with $10^{-5}M$ hexamethonium (nicotinic receptor antagonist) significantly inhibited the magnitude of the nicotine associated contractions. The nicotine-induced contractions were not only significantly inhibited by pretreatment with $10^{-5}M$ indomethacin (nonspecific cyclooxygenase inhibitor) and with $10^{-6}M$ NS-398 (selective cyclooxygenase inhibitor), but also with $10^{-6}M$ Y-27632 (Rho kinase inhibitor). Ozagrel (thromboxane $A_2$ synthase inhibitor) and SQ-29548 (highly selective TP receptor antagonist) pretreatments significantly reduced the nicotine-induced contractile amplitude of the strips. High concentrations of nicotine caused contraction of isolated rabbit corpus cavernosal strips. This contraction appeared to be mediated by activation of nicotinic receptors. Rho-kinase and cyclooxygenase pathways, especially cyclooxygenase-2 and thromboxane $A_2$, might play a pivotal role in the mechanism associated with nicotine-induced contraction of the rabbit corpus cavernosum.

• Archives of Plastic Surgery
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• 제36권5호
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• pp.565-570
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• 2009

Purpose: Numerous techniques have been introduced to reconstruct the perineal area in order to preserve function of both the recipient and the donor site while satisfying aesthetic results. There are several advantages of using the pudendal aretery perforator based flap in that it provides thin coverage of defect area and a relatively excellent circulation through perforators. The perineal region can be divided into two areas : the urogenital triangle and the anal triangle. Since each area differs in structure and function so does its reconstructive plan. The authors of this article report clinical results obtained from pudendal artery perforator based reconstructed cases according to each differrent triangles. Methods: A total of 15 patients who underwent perineal reconstruction were enrolled in our study between the year 2002 and 2006. There were 4 cases of vaginal cancer, 4 cases of extramammary Paget's disease, 1 case of rectovaginal fistula in females and 2 cases of Paget's disease and 4 cases of Fournier's gangrene in male cases. The follow up period was on average 6 month. In female, superfical pudendal artery perforator based local flap were used to reconstruct the urogenital triangle defects, while internal pudendal artery perfoator based local flaps were used to reconstruct the anal traingle defects. In males the gracilis myocutaneous flap and internal pudendal artery perforator based local flaps were used in reconstruction of the scrotum and perineal defect. Result: In females, there was 1 case of partial flap necorsis that employed the superficial pudendal artery perforator but secondary repair through the internal pudendal artery perforator based local flap was done. In addition, there were 4 wound dehiscence cases in females and 2 cases in males. Conclusion: We believe that a better aesthetic and functional outcome can be achieved in perineal reconstruction if discrete surgical planning is carried out systematically categorizing the choice of flap employed acccording to distinct anatomical regions : the urogenital and the anal triangle.