• 동아시아식생활학회지
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• 제3권2호
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• pp.41-50
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• 1993

This study was intended to investigate the relationship of dietary Na and Ca intake and excretion in blood pressure regulation of free-living adults. Two separate surveys were conducted for 294 subjects in Taegu area, The results of this study are as follows ; When subjects were divided into normotensive and hypertensive, there were significant differences in age, BMI between two groups, When dietary intake were compared between two groups, no significant differences in energy, carbohydrates, fat and protein intakes were shown. While Na intake of hypertensive groups was not signidicantly different from that of normotensive groups, While Na intake of hypertensive groups was not significantly different from that of normotensive groups, ca intake of hypertensive group was significantly lower than that of normotensive group(P<0.005), Urinary Na excretion was significantly higher(P<0.05) in hyperten sive group. However, urinary Ca and K excretion in both groups were not significantly different. Urinary sodium was significantly correlated with urinary Ca and Na intake. Multiple regression analysis of variables showed that urinary sodiumwas affected by Na index, age and Ca Index. While urinary Ca, was significantly correlated with urinary Na and K excretion, it did not show significant correlation with Ca intake

• 동아시아식생활학회지
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• 제5권1호
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• pp.67-74
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• 1995

The aim of this study was to investigate the interrelationship among urinary excretion dietary habit of Na, Ca intake and hormonal factors in 22 hypertensive and 30 normotensive hospitalized patients. The results were summarized as follows : 1. Urinary excretion of Na in normotensive patients was not significantly different from that of hypertensive patients, while Ca excretion(as expressed on the basis of mg of creatinine) was significantly higher in hypertensive patients. 2. Habitual dietary intake of Na, Ca in hypertensive patients were not significantly different from those of normotensive patients. 3. There were no significant differences in mean plasma renin activity, aldosterone and parathyroid hormone(PTH) level between two groups. However, systolic pressure significantly correlated with PTH(r=0.2597) and aldosterone level(r=0.24648)(P<0.05). In this study blood pressure did not show any significant relationship between urinary Na excretion and habitual dietary Na intake of Na. It is speculated that individual difference of Na sensitivity might result in heterogenous blood pressure response to dietary Na intake. Higher Ca excretion in hypertensive subjects suggested a future study on the interrelationship between Ca metabolism and aldosterone system in hypertension.

• Journal of Community Nutrition
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• 제1권2호
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• pp.119-124
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• 1999

The purpose of this study is to investigate the daily variation of Na intake as measured by dietary methods(weighing vs food analysis) and to examine the difference between urniary Na excretion and dietary Na intake in 9 healthy free living women aged 25-64 years living in Taegu, Korea. Information on the dietary Na intake for 5 consecutive days was collected using he weighing method. Twenty four-hour urine samples were collected for the same period to measure the urinary Na excretion. In order to figure out the difference of Na intake with respect to dietary assessment methodology, dietary intake was measured by the weighing method for three of a total 5 days. At the same time, the meals that subjects consumed each day were collected to analyze daily intake of each subject by the food analysis method. The mean Na intake of subjects for 5 consecutive days by the weighing method was 3558. 5mg. The mean of urinary Na excretion for the same period was 2847.5mg/ Na intake and Urinary Na excretion of each subject ranged from 4475.3 to 2838.4, from 4066.4rmg to 1936.1mg respectively. The mean of Na intake for 3 days by the analysis method and the weighing method were 3044.6mg and 3441.6mg, respectively. Each subject showed a great difference among day-to-day variation of Na intake by the weighting method, analysis method and urinary Na excretion method. Therefore, a short term study period may not be valid to estimate the true average Na intake.

• Journal of Nutrition and Health
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• 제30권6호
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• pp.669-678
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• 1997

This study was designed to estimate the sodium intake of preschool children . To determine the sodium intake & excretion of preschool children in Korea, dietary behaviors, anthropometry, intakes of dietary nutrients, urinary sodium excretion and preference for salty foods were measured in 42 preschool children (male 26 , female 16, average6.5 years old) and their mothers. The results are summarized as follows. Mean daily urinary sodium excretion was 52.7 mEq(1,212.1mg). This value did not show remarkable change compared with the other studied that were accomplished in the similarage group for about the last ten years. And the subjects showed lower preference for salty taste than those of elementary school children and adults. Mean daily lower preference for salty taste than those of elementary school children and adults. Mean daily urinary sodium excretion were significantly correlated with the frequency of eating out (p<0.01), potassium intake(p<0.001) and urinary sodium to potassium excretion ratio(p<0.001). But there weren't any correlations with mean daily sodium intake, blood pressure, dietary nutrients intake and the preference for salty taste.

• Journal of Nutrition and Health
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• 제20권5호
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• pp.341-349
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• 1987

Dietary intakes of na include both the amount present in food materials (nondiscretionary Na intake) and the amount added during cooking and eating to increase salty taste and flavor (discretionary Na intake). In the present study, total Na intake was measured by duplicate food sample collected from each subject for 1 day, nondiscretionary Na intake was calculated by dietary intake record, optimum gustation of salt was measured of from pooled 3-day urine collection in healthy female college students, to measure Na intake more accurately and to find suitable method to estimate total Na intake. Mean values of total, discretionary and mondiscretionary Na intakes were 169.6 mEq, 46.2mEq, and 123.4mEq. respectively. Mean 24-hour urinary Na excretion was 137.9mEq., which was about 84.5% of total intake. Subjects with optimum gustation of salt equal to or higher than 0.5% had significantly higher total Na intake and urinary Na excretion compared to subjects with optimum gustation of salt lower than 5%. Total Na intake of subjects were significantly correlated with optimum gustation of salt, non-discretionary and discretionary Na intakes, and urinary Na excretion. Multiple regression analysis showed that the best estimate of total Na intake is obtained when both optimum gustation of salt and non-discredinary Na intake were used as independent variables (r=.7071). Among the equations using one independent variable, regression, equation with urinary Na excretion provides the best approximation (r=.6627) of total Na intake.

• 대한영양사협회학술지
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• 제3권2호
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• pp.159-168
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• 1997

This study was conducted to examine the effects of Na, K intake and stress level on the blood pressure and urinary excretion of Na, K in the third grade lacto-ovo vegetable male high school students. Twenty-one lacto-ovo vegetarian male high school students were selected, and their physical state, stress level, dietary intake and urinary excretion of Na, K were measured followed by examining the relationship among these factors and blood pressure. The results of the study can be summarized as follows : 1. The average age of the subjects was 17.7 years, and the average score of BMI was 20.4. The average score of Rohrer and blood pressure were 119.1, 112.3/7.5mmHg, each. All of these were in a normal range. Daily calorie intake was 2676.8kcal and Na, K intakes were 152.76mEq, respectively. 2. 71.4% of subjects were susceptible to the disease associated with stress, although there was no significant difference among the salt level, stress and blood pressure. 3. There was significant difference between dietary Na intake ratio, urinary Na excretion and urinary K excretion rate (p<0.001). 4. There was significant difference between systolic blood pressure and BMI/Rohrer score(p<0.01).

• Toxicological Research
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• 제5권2호
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• pp.79-87
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• 1989

Changes in urinary $Na^+$ and $K^+$ excretions, renal cortical microsomal $Na^+$ -K-ATPase activity, cortical tissue electrolyte content and plasma aldosterone level were studied in rats treated with CdCl2 (2 mg Cd/kg/day, s.c. injection) for 7-14 days. After 7 days of cadmium exposure, urinary excretion of $Na^+$ was markedly reduced. This change was accompanied by an increase in $Na^+$-$K^+$-ATPase activity, a fall in tissue $Na^+$ content, a rise in tissue $K^+$ content and an elevation of plasma aldosterone level.

• The Korean Journal of Physiology
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• 제9권2호
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• pp.33-39
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• 1975

Changes of urinary aldosterone excretion, concurrent sodium and potassium excretion following furosemide administration were studied in normotensive young Korean with high sodium intake, moderate sodium restriction and marked sodium depletion. After intravenous injection of furosemd 40mg, plasma and urine samples were collected at every thirty minutes for two hours. Plasma-and urinary aldosterone, electrolyte concentration and urine flow rate were measured by means of radioimmunoassay or flamephotometry. Relations of urinary aldosterone to concurrent sodium or potassium/sodium ratio, and of urinary aldosterone to concurrent plasma aldosterone activity were studied. Following were the results: 1. Furosemide administration resulted in a increased urinary aldosterone concentration and unchanged or somewhat decreased sodium concentration in course of time after the injection. 2. Urinary potassium concentration showed initial decrease and subsequent increase in course of time after furosemide administration and it resulted in a gradual increase in urinary potassium/sodium ratio. 3. Studying the relations between urinary aldosterone excretion and potassium/sodium excretion ratio, or sodium excretion were meaningless because of the urinary flow rate after the injection was decreased with time course. 4. Furosemide administration showed a good relationship of urinary aldosterone concentration to concurrent potassium/sodium ratio rather than concurrent sodium concentration in subjects with sodium restriction, but no meaningful relationship was detected in subjects with high sodium intake because increasing rate of the ratio was not so wide. 5. Furosemide also resulted a reasonable relation of plasma aldosterone concentration to concurrent urinary aldosterone concentration especially during low sodium intake. 6. Above results suggested that relation of urinary aldosterone concentration to K/Na ratio following furosemide administration during sodium restriction is significant and has a benefit to reduce the variation induced by kalemic change showing in the diragram for daily aldosterone to sodium excretion.

• Journal of Nutrition and Health
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• 제29권10호
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• pp.1096-1104
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• 1996

This study was performed to evaluate the effect of sodium cholride supplementation on bone metabolism in female rats consuming a low calcium diet. Twenty five female rats were divided into three dietary groups (control Na : 0.1038%, 1% Na : 1.036%, 2% Na : 2.072%). All experimental diets contained 0.27% Ca and were fed to rats with deionized water for 7 weeks. Bone mineral density(BMD) and bone mineral content(BMC) of total body, spine and femur were measured using energy x-ray absorptiometry(DEXA) by small animal software. Then Ca efficiency was calculated from BMD and BMC. Serum Ca, P, Na and urine Ca, P, Na were determined. Urinary pyridinoline, serum ALP were measured to monitor bone resorption. Following 7 weeks, sodium cholride supplemented groups had higher urinary Ca excreteion, urinary pyridinoline, crosslinks value and serum ALP. There was no significant difference in case of serum Ca among all groups. Sodium chloride supplemnted groups had lower Ca effciency of total, spine and femur BMD and BMC than that of control group. In conclusion high salt intake not only increases urinary Ca excretion as urinary Na excretion does but also increase bone resorption and decrease Ca efficiency of each bone. It is been suggested that high salt intake may be harmful for bone maintenance. Therfore, the decrease of salt intake to the level of recommendation would be desirable.

• 대한지역사회영양학회지
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• 제1권1호
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• pp.71-78
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• 1996

This study was conducted to compare the dietary factors which influence on the bone status of 28 women in urban and 30 women in rural area. Urinary excretion of hydroxyproline(Hpr) and Calcium(Ca) were measured as biological markers of bone resorption. Mean daily intake levels of total protein, animal protein, total calcium, calcium, calcium from milk and milk products, animal calcium, Ca / P ratio by 24 hr recall method were significantly higher in urban women. However, mean daily sodium(Na) intake levels were not significantly different between two groups. Ca Index score and Na Index score by food frequency methods were also significantly higher in urban than in rural subjects. While urinary Ca excretion elves of two groups were similar, Na excretion levels were significantly higher in rural women. Mean urniary levels of Ca / creatinine(cr) and Hpr / cr as bone status index were within normal range and not significantly different between two groups. However, prevalence of poor bone status as assessed by hydroxyproline was higher in rural women. Na Index, urinary Ca excretion and Ca / cr ratio were significantly correlated with bone status(Hpr / cr) in urban women, while only age was related to bone status in rural women. These demonstrated that high Na intake results in increased urinary excretion of Na and Ca and could cause bone resorption. Multiple regression analysis indicated that Na Index score and age have greater effect than other variables in urban women and only age has greater effect in rural women.