• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.10 no.5
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• pp.127-135
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• 2015

The initial start-up founders are also often successful and sometimes unsuccessful. Conditions of establishment, it is necessary to management strategies such as site selection and strong entrepreneurial spirit with matching funds force to their aptitude. However, novice founder, in real estate transactions, there is a case in which a freak accident, such as the double sale occurs. South Korea's real estate transactions practice, difficult subject to systematic support, even as has been resolved legally, the damage of the victim so that the difficult issues that remain intact occurs. Therefore, beyond the problem to punish the perpetrators in such breach of trust crimes a legally double trade to this, is the strategy through the management histological approach received victim now of damage is required. We want to be viewed as discussion of What about the management strategy for accident prevention of real estate transactions in elementary founder accident concerning transactions such as real estate of double trafficking.

• Journal of Ginseng Research
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• v.48 no.3
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• pp.310-322
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• 2024

Background: Osteosarcopenia is a common condition characterized by the loss of both bone and muscle mass, which can lead to an increased risk of fractures and disability in older adults. The study aimed to elucidate the response of various mouse strains to treatment with Rg3, one of the leading ginsenosides, on musculoskeletal traits and immune function, and their correlation. Methods: Six Collaborative Cross (CC) founder strains induced muscle atrophy and bone loss with dexamethasone (15 mg/kg) treatment for 1 month, and half of the mice for each strain were orally administered Rg3 (20 mg/kg). Different responses were observed depending on genetic background and Rg3 treatment. Results: Rg3 significantly increased grip strength, running performance, and expression of muscle and bone health-related genes in a two-way analysis of variance considering the genetic backgrounds and Rg3 treatment. Significant improvements in grip strength, running performance, bone area, and muscle mass, and the increased gene expression were observed in specific strains of PWK/PhJ. For traits related to muscle, bone, and immune functions, significant correlations between traits were confirmed following Rg3 administration compared with control mice. The phenotyping analysis was compiled into a public web resource called Rg3-OsteoSarco. Conclusion: This highlights the complex interplay between genetic determinants, pathogenesis of muscle atrophy and bone loss, and phytochemical bioactivity and the need to move away from single inbred mouse models to improve their translatability to genetically diverse humans. Rg3-OsteoSarco highlights the use of CC founder strains as a valuable tool in the field of personalized nutrition.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2003.04a
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• pp.85-86
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• 2003

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.16 no.1
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• pp.21-35
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• 2021

Based on social capital theory, this study investigated the influence of the start-up founder's social competence on the start-up's access to funding sources and performance through the mediating role of the type of social network. This study aimed to examine two types of social networks empirically (i.e., personal networks and business networks) as social capital in analyzing the effect of the founder's social competence and social capital on the method of accessing funding sources. A self-report questionnaire was administered to 252 South Korean start-up founders whose businesses are based in South Korea. Path analysis and mediation effect analysis were performed by structural equation modeling(SEM) using STATA 16.1. This study examined the full mediating effect of the founder's social competence on his/her personal and business networks, respectively, and how the effect leads to different methods to approach funding sources. This is the first study in South Korea to analyze empirically how social competence has contrasting effects on personal and business networks as well as how each type of network varies in its influence on the method founders use to attract investment. This study is also significant in that it proposed a new methodology by utilizing the position generator as the measure of personal and business networks to analyze social networks in detail. The analyses of 252 survey data collected over a period of six months will be a valuable resource that may provide researchers, founders, investors, and other stakeholders in the start-up ecosystem with meaningful implications.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.18 no.6
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• pp.27-40
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• 2023

This study analyzes the factors affecting the survival of young start-up companies. A youth start-up company was defined as a company with a founder's age under 39. The study was based on evaluation data from 3,540 companies evaluated by the Technology Guarantee Fund to support youth start-up guarantees during the period from 2012 to 2015. In this study, independent variables were defined as founder characteristics, start-up environment, and start-up strategy, and entrepreneurship, knowledge level, and development capabilities were set as variables for start-up characteristics, competition conditions and comparative advantage with alternatives in the start-up environment, and item novelty, commercialization plan and financing plan were set as variables. For variable measurement, the evaluation index of the youth start-up evaluation model of the Technology Guarantee Fund was used. Management performance was defined as the survival of a company, and the survival of 12, 36, 60, and 84 months was measured based on the occurrence of insolvency registered by the Korea Technology Guarantee Fund. The Cox proportional risk model was used for hypothesis testing. As a result of the analysis, knowledge level and development capability were statistically significant in the characteristics of the founder, and the financing plan in the start-up strategy was statistically significant regardless of the survival period. Among the start-up strategies, the novelty of the item had a positive effect on survival after 36 months. Entrepreneurship was significant only in 12-month survival. The most important order for survival was identified in the order of financing plan, knowledge level, item novelty and development capability, of which the founder's knowledge level in the beginning and the funding plan in the second half had the greatest impact.

• Journal for History of Mathematics
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• v.19 no.1
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• pp.17-32
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• 2006

Topology began to be studied relatively later than the other branches of mathematics, such as geometry, algebra and analysis. Leonhard Euler is generally considered to be the founder of topology. In this paper we first investigate the beginning of topology and its development and then study Euler's life and his achievements in mathematics.

• Journal of Industrial Convergence
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• v.18 no.6
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• pp.1-7
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• 2020

In this study, we hypothesized that the needs for start-up support services may vary depending on the founder's psychological characteristics, such as self-efficacy or his attitude toward uncertainty. To verify this, a survey was conducted on the founders of 86 companies located in Business Incubators at Seoul and Daejeon and an empirical analysis was conducted based on the data. According to the analysis, the higher the self-efficacy of the founder, the more active he expressed his willingness to accept the start-up support service, which aims to provide start-up zones to busy areas outside the university. While the founder, who has experienced failure in the past, responded positively to attracting customers located outside the university. The results of this study supported the hypothesis and suggest that differentiated start-up support services should be designed by including not only characteristics at the level of start-up companies, such as industries and growth stages, but also the psychological characteristics of start-ups in important consideration.

• Asia Marketing Journal
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• v.24 no.4
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• pp.152-160
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• 2023

A great deal of attention has been paid to entrepreneurship and social enterprises that help improve societies' ability to solve social problems and develop new ways of thinking (Drucker 1995). Dong Wha Pharm, founded in 1897, was the first social enterprise in South Korea. The purpose of this study is to provide meaningful insights into the theoretical development of social entrepreneurship and how to achieve social innovation by fostering social entrepreneurship. Drawing on the five critical elements of social entrepreneurship developed by Dees (1998), we explore social entrepreneurship by investigating the first Korean social entrepreneur, Kang Min, the founder of Dong Wha, a 125-year-old company in South Korea. The findings offer meaningful and valuable insights to the literature on social entrepreneurship and to current and potential social entrepreneurs wanting to find new ways to achieve social improvement and move society forward.

• Culinary science and hospitality research
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• v.21 no.6
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• pp.1-13
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• 2015

This study was performed to empirically verify how the degree of entrepreneurial self-efficacy, the degree of work value which each founder gains from starting a shop, and the degree of usefulness perception of the entrepreneurial service given by the public sector influence founder's entrepreneurial intentions. The degree of entrepreneurial self-efficacy and internal work value was found to influence entrepreneurial intentions. In addition, would-be coffee shop founders' usefulness perception of entrepreneurial service had an impact on entrepreneurial intention. The results of this study could allow a wider understaning of what factors influence entrepreneurial intentions of a coffee shop founder and the importance of governmental support(education, funding, skills, and management).

• Korean Journal of Animal Reproduction
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• v.25 no.1
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• pp.85-90
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• 2001

To study the signaling effect of growth hormone (GH) in vivo on animal physiology, transgenic mice containing GH Receptor (GHR) gene fused to metallothionein promoter were produced by DNA microinjection into one-cell stage embryos. Three founder mice were produced with transgenic mice with approximately 4~6 copies of GHR genes and transgene was transmitted into the progeny. The founder mice were mated with normal mice to produce F$_1$ mice, and intergation and transmission of transgene were checked by polymerase chain reaction and Southern blot methods. Transmission rate of GHR transgenic mice were 20~50% in F$_1$ generation and 50% in F$_2$ generation which means that some founder mice were mosaic and transgene in F$_1$ mice was transmitted to F$_2$ progeny with Mendelian ratio. Death rate of GHR transgenic mice after birth was about 10~30% in F$_1$ and F$_2$ progenies indicating that GHR gene may affect death of transgnenic progeny.