• The Korean Nurse
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• v.11 no.3 s.59
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• pp.38-44
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• 1972

The common cold is a symptom complex caused by viral infection of the upper respiratory passages. Most precisely, the term applies to febrile, acute coryza of viral origin. In broadest sense, the common cold refers to any undifferentiated upper respirator

• 대한핵의학회:학술대회논문집
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• 1998.11a
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• pp.39.1-39.1
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• 1998

• BMB Reports
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• v.30 no.3
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• pp.194-199
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• 1997

Previous studies have shown that the HD3 human enterocytic differentiated colon carcinoma cell lines having low $PKC{\beta}$ activity did not respond to diacylglycerol and basic FGF by growth and by activation of pp57 MAP kinase, but undifferentiated cell lines exhibiting high $PKC{\beta}$ activity did. To confirm a role of $PKC{\beta}$ in colonocyte mitogenesis, derivatives of HD3 cell line that stably overexpress a full-length of cDNA encoding the ${\beta}_1$ isoform of human PKC were generated. The abundance and activity of $PKC{\beta}$ in two of the these cell lines, PKC3 and PKC8 were much higher than those in the C1 control cell line that carries the vector lacking the $PKC{\beta}_1\;cDNA$ insert. Following exposure to diacylglycerol or basic FGF, proliferation of PKC3 and PKC8 cells increased about 50%; but this effect was not seen with the control C1 cells. Also, in contrast to the control cells, the $PKC{\beta}_1-overproducing$ cells displayed activation of pp57 MAP kinase when treated with diacylglycerol and basic FGF as undifferentiated cell lines did. These results provide direct evidence that $PKC{\beta}_1$ which plays a key role in mitogenic responses of colon carcinoma cells to diacylglycerol and basic FGF is down-regulated in enterocytic differentiation of colon cells.

• Applied Microscopy
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• v.20 no.2
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• pp.12-22
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• 1990

The morphological characteristics and changes of the foregut in the grasshopper (Oxya sinuosa Mistshenko) have been studied with the special reference to the developmental stage. In light microscope level, the epithelia are seen the cuboidal shape in the 5th instar nymph and the adult. A number of pigment granules are appeared in the cuboidal epithelium of the 5th instar nymph, however the pigment granules were a few in the adult. Indistinct or undifferentiated folds of the epithelial layer were appeared in the 5th instar nymph, whereas the well-developed folds were in the adult. The well-developed muscular layers are seen in the 5th instar nymph, however in the adult the muscular layers are appeared thin or a few layer except the crop. In electron microscope level, in the foregut epithelium, a few round or oval shaped mitochondria, well-developed rER, Golgi complex, lysosome and a number of vacuoles were appeared in the cytoplasm. Two types of pigment granules, electron dense or homogenous and low electron dense or lamellar profiles, are seen in the esophageal epithelium. The crystalline profiles and plasma membrane infoldings were also appeared. In the foregut epithelium of the 5th instar nymph, however the cell organelles were generally undifferentiated and in the crop two types of pigment granules as the adult esophageal epithelium were also found.

• Korean Journal of Human Ecology
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• v.20 no.1
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• pp.71-90
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• 2011

The aim of this study was to investigate on characteristics of sociological and demographic population, marital conflicts and expectations to family counselors' cultural competence surrounding factors of cultural adaptation among immigrated women. This study conducted a survey of 236 immigrated women in Kyonggi province, Seoul metropolitan cities, Cholla and Chunchung provinces and Incheon. The results of this study are as follows: First, a relatively few marital conflicts were found, as a whole, while they had the high levels of expectation to family counselors' cultural competence. Second, immigrated women can be clustered as three different types: 'multiplicity type', 'undifferentiated type' and 'adaptation type'. Third, sociological and demographic population characteristics which were subdivided and clustered according to cultural adaptation made the significant difference between each population. Population with multiplicity type out of the above-stated three types accounted for the highest conflict rates, while population with 'adaptation' type accounted for the lowest conflict rates. Lastly, expectations to family counselors' cultural competence made the significant difference among each population. Population with multiplicity type showed the highest expectation levels on expectations to family counselors' cultural competence, while population with undifferentiated type showed the lowest levels.

• Reproductive and Developmental Biology
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• v.31 no.4
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• pp.221-226
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• 2007

Embryonic stem (ES) cells are known to have an infinite proliferation and pluripotency that are associated with complex processes. The objective of this study was to examine expression of genes differentially regulated during differentiation of human ES cells by suppression subtractive hybridization (SSH). Human ES cells were induced to differentiate into neural precursor cells via embryoid body. Neural precursor cells were isolated physically based on morphological criteria. Immunocytochemical analysis showed expression of pax6 in neural precursor cells, confirming that the isolated cells were neural precursor cells. Undifferentiated human ES cells and neural precursor cells were subject to the SSH. TPX2 (Targeting Protein for Xklp2 (Xenopus centrosomal kinesin-like protein 2)) was identified, cloned and analyzed during differentiation of human ES cells into neural lineages. Expression of TPX2 was gradually down-regulated in embryoid bodies and neural precursor cells relative to undifferentiated ES cells. Targeting Protein for Xklp2 has been shown to be involved in cell division by interaction with microtubule development in cancer cells. Taken together, result of this study suggests that TPX2 may be involved in proliferation and differentiation of human ES cells.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.13 no.1
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• pp.17-27
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• 1983

The author observed the effects of /sup 60/Co irradiation on the development and subcellular structure of tongue tissue of the fetal rats. The lower left abdomen of mothers were exposed to radiation on 15½th day of gestation with 300R. The fetuses were removed on the 6hr, 14hr, 24hr, 48hr and 72hr after irradiation and the light microscopic and electron microscopic observations of the lingual epithelium, lamina propria and muscle layer were carried out. The results were as follows: 1. The irradiated fetuses showed the retardation of filiform papillae formation. 2. Epithelial cells revealed fusion and myelination of mitochondria, large autolysosomes, increased lipid droplets, retardation of tonofilaments and desmosome formation. 3. In the lamina propria, undifferentiated cells showed bleb formation of nuclear membrane, pyknosis and fragmentation of nucleus, edema of cytoplasm I and nucleus, increased auto-lysosomes, dilatation of cell membrane and cell necrosis. Also, collagenous fibril formation was inhibited by irradiation. 4. In the muscle layer, growth of myotubes was inhibited. Myotubes showed swelling of mitochondria, loss of mitochondrial cristae, autolysosomes, retardation of myofibril formation, and large vacuoles. Undifferentiated cells adjacent myotube contained pyknotic nucleus and autolysosomes. 5. Among the various tissues of tongue, it seems that mesenchymal cells were most radiosensitive.

• The Journal of Korean Academic Society of Nursing Education
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• v.15 no.1
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• pp.100-108
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• 2009

Purpose: This study explored the relationship between types of gender role identity and health behaviors in 500 adults. Method: Data was collected with self-reporting questionnaire forms from April 23 to May 4, 2007. using the Korean Gender Role Identity Inventory and Health Behavior Assessment Tool. Results: The mean (SD) was 2.65 (0.42) for gender role identity, and 2.61 (0.38) for health behaviors. The subjects were classified into four gender role identity types; 30.4% in undifferentiated, 27.8% in androgyny, 22.4% in masculinity, and 19.4% in femininity. Four gender role identity types of subjects showed significant different levels of health behaviors (F=40.33, p<.001). The androgyny type subjects reported the highest mean of health behaviors scores, and the undifferentiated type subjects had the lowest mean. There were significant differences in health behaviors according to subjects' general characteristics, such as age, marital status, perceived health status, and smoking (p<.005). Conclusion: There is a need to make changes in family, school, and society toward better environments for helping adults develop desirable gender role identity. In addition, the gender role identity in adults has to be considered in establishing healthy lifestyles and developing health promotion programs.

• Tuberculosis and Respiratory Diseases
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• v.75 no.4
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• pp.161-164
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• 2013

Eosinophilic pleural effusion (EPE) is defined as a pleural effusion that contains at least 10% eosinophils. EPE occurs due to a variety of causes such as blood or air in the pleural space, infection, malignancy, or an autoimmune disease. Undifferentiated connective tissue disease (UCTD) associated with eosinophilic pleural effusion is a rare condition generally characterized by the presence of the signs and symptoms but not fulfilling the existing classification criteria. We report a case involving a 67-year-old man with UCTD and EPE, who has been successfully treated with a single intrapleural corticosteroid injection.

• Child Health Nursing Research
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• v.24 no.2
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• pp.178-185
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• 2018

Purpose: This study aimed to investigate perceptions of child abuse and factors influencing those perceptions among nursing students. Methods: A descriptive research design was used with a convenience sample of 669 nursing students. Data was collected from September 1 to 25, 2016 using self-report questionnaires and analyzed with descriptive statistics, the t-test, analysis of variance, the Pearson correlation coefficient, and multiple regression analysis in SPSS for Windows version 21.0. Results: The mean score for perceptions of child abuse was $3.52{\pm}0.41$, and the scores by subcategory were as follows: physical abuse, $3.61{\pm}0.39$; emotional abuse, $3.54{\pm}0.53$; neglect, $3.17{\pm}0.69$; sexual abuse, $3.85{\pm}0.35$. A significant correlation was found between perceptions of child abuse and parental acceptance-rejection attitude (warmth/affection, indifference/neglect, undifferentiated rejection). The factors influencing perceptions of child abuse were gender, experiences of child abuse, and perceived parental attitudes of warmth/affection and undifferentiated rejection, which explained 5.1% of the variances. Conclusion: Based on the finding of this study, educational programs and guidelines should be developed to help nursing students improve their perceptions of child abuse.