• Title/Summary/Keyword: under-determined system

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Instrumentation and system identification of a typical school building in Istanbul

  • Bakir, Pelin Gundes
    • Structural Engineering and Mechanics
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    • v.43 no.2
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    • pp.179-197
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    • 2012
  • This study presents the findings of the structural health monitoring and the real time system identification of one of the first large scale building instrumentations in Turkey for earthquake safety. Within this context, a thorough review of steps in the instrumentation, monitoring is presented and seismic performance evaluation of structures using both nonlinear pushover and nonlinear dynamic time history analysis is carried out. The sensor locations are determined using the optimal sensor placement techniques used in NASA for on orbit modal identification of large space structures. System identification is carried out via the stochastic subspace technique. The results of the study show that under ambient vibrations, stocky buildings can be substantially stiffer than what is predicted by the finite element models due to the presence of a large number of partitioning walls. However, in a severe earthquake, it will not be safe to rely on this resistance due to the fact that once the partitioning walls crack, the bare frame contributes to the lateral stiffness of the building alone. Consequently, the periods obtained from system identification will be closer to those obtained from the FE analysis. A technique to control the validity of the proportional damping assumption is employed that checks the presence of phase difference in displacements of different stories obtained from band pass filtered records and it is confirmed that the "proportional damping assumption" is valid for this structure. Two different techniques are implemented for identifying the influence of the soil structure interaction. The first technique uses the transfer function between the roof and the basement in both directions. The second technique uses a pre-whitening filter on the data obtained from both the basement and the roof. Subsequently the impulse response function is computed from the scaled cross correlation between the input and the output. The overall results showed that the structure will satisfy the life safety performance level in a future earthquake but some soil structure interaction effects should be expected in the North South direction.

Identification of 3'-Hydroxymelanetin and Liquiritigenin as Akt Protein Kinase Inhibitors

  • Yang Hye-Young;Lee Hong-Sub;Ko Jong-Hee;Yeon Seung-Woo;Kim Tae-Yong;Hwang Bang-Yeon;Kang Sang-Sun;Chun Jae-Sun;Hong Soon-Kwang
    • Journal of Microbiology and Biotechnology
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    • v.16 no.9
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    • pp.1384-1391
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    • 2006
  • The signal transduction system is one of the most important devices involved in maintaining life, and many protein kinases are included in the cellular signal transduction system. Finding a protein kinase inhibitor is very valuable, as it can be used to study cell biology and applied to pharmaceuticals. For the efficient and rapid screening of protein kinase inhibitors, two assay systems were combined; the nonradioactive protein kinase assay system that uses an FITC-labeled IRS-2 peptide and the cell-based paper disc assay system that uses Streptomyces griseus as the indicator strain. Among 330 kinds of herb extracts tested, the extract of Dalbergia odorifera exhibited the strongest inhibitory activity in the two assay systems and was selected for further isolation. Based on solvent extraction and many steps of chromatography, seven compounds were finally separated to homogeneity and their structures determined by $^{1}H$ and $^{13}C$ NMR spectroscopies. Four were to be flavonoids and identified as butin ($C_{15}H_{12}O_5$, Mw=272.07), 3'-hydroxymelanetin ($C_{16}H_{12}O_6$, Mw=300.06), liquiritigenin ($C_{15}H_{12}O_4$, Mw=256.07), and 2'-hydroxyformononetin ($C_{16}H_{12}O_{5}$, Mw=284.07). 3'-Hydroxymelanetin inhibited the phosphorylation of the GSK3 protein by Akt to 37% at a concentration of $10{\mu}g/ml$ and showed the strongest cytotoxicity ($ED_{50}<50{\mu}g/ml$) against the human cancer cell line HCT116. Under the same conditions, liquiritigenin also inhibited the phosphorylation of GSK3 by Akt to 26%, and its cytotoxicity against the HCT116 cell line was lower than $100{\mu}g/ml$.

A Study on the Body Shape for Chinese Adult Women of Development of Apparel Sizing System (중국(中國) 성인(成人) 여성용(女性用) 의류치수규격(衣類値數規格) 성정(設定)을 위(爲)한 체형(體型) 연구(硏究) 제1보(第1報))

  • Wee, Hye-Jung;Sohn, Hee-Soon
    • Journal of Fashion Business
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    • v.9 no.5
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    • pp.15-36
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    • 2005
  • The purpose of this study was to provide for the useful fundamental data by developing an appearl sizing system according to body types for Chinese adult female. Thus, it was to improve of fittness and coverage rate of exporting domestic clothing to China. As a sample, 1360 female women was seleted aged between 19 and 50 who resident in Beijing and Shanghai in China for characterization body types and development of apparel sizing system by classifying them. As for the method of this study was made of 111 items by indirect measures done during Jun. 23 $\sim$ Aug. 7, 2004. Data analysis were processed by SPSS WIN 10.0 Program was used to for technical statistical analysis, ANOVA(t-test and F-test), factor analysis, duncan's multiple test. The results from the study were as follows: As they are getting older, the horizontal size and length categories related to width, thickness, and circumference increased, and the height and vertical size that show the vertical size of body reduced. 1. The women in the Shanghai area had large head width, head thickness and head circumference, the categories related to the height and head, and the women in the Beijing area had larger in terms of width, circumference, length, angle and other categories. 2. Chinese Adult women's constitutional components determined by factor analysis, six components could be identified: factor 1 : constitutional obesty and width size, factor 2 : longistudinal body size, factor 3 : shoulder form and size, factor 4 : longistudinal upper body size, factor 5 : longistudinal under body size, factor 6 : shoulder dropping.

Scoring Model Based on Nodal Metastasis Prediction Suggesting an Alternative Treatment to Total Gastrectomy in Proximal Early Gastric Cancer

  • So, Seol;Noh, Jin Hee;Ahn, Ji Yong;Lee, In-Seob;Lee, Jung Bok;Jung, Hwoon-Yong;Yook, Jeong-Hwan;Kim, Byung-Sik
    • Journal of Gastric Cancer
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    • v.22 no.1
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    • pp.24-34
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    • 2022
  • Purpose: Total gastrectomy (TG) with lymph node (LN) dissection is recommended for early gastric cancer (EGC) but is not indicated for endoscopic resection (ER). We aimed to identify patients who could avoid TG by establishing a scoring system for predicting lymph node metastasis (LNM) in proximal EGCs. Materials and Methods: Between January 2003 and December 2017, a total of 1,025 proximal EGC patients who underwent TG with LN dissection were enrolled. Patients who met the absolute ER criteria based on pathological examination were excluded. The pathological risk factors for LNM were determined using univariate and multivariate logistic regression analyses. A scoring system for predicting LNM was developed and applied to the validation group. Results: Of the 1,025 cases, 100 (9.8%) showed positive LNM. Multivariate analysis confirmed the following independent risk factors for LNM: tumor size >2 cm, submucosal invasion, lymphovascular invasion (LVI), and perineural invasion (PNI). A scoring system was created using the four aforementioned variables, and the areas under the receiver operating characteristic curves in both the training (0.85) and validation (0.84) groups indicated excellent discrimination. The probability of LNM in mucosal cancers without LVI or PNI, regardless of size, was <2.9%. Conclusions: Our scoring system involving four variables can predict the probability of LNM in proximal EGC and might be helpful in determining additional treatment plans after ER, functioning as a good indicator of the adequacy of treatments other than TG in high surgical risk patients.

SNU 1.5 MV Van de Graaff Accelerator (V) -on the Operation of the High Voltage Stabilization System- (NU 1.5MV 반데그라프 가속기 (V) -고전압 안정화 계통의 동작-)

  • Bae, Y.D.;Bak, H.I.;Chung, K.H.;Woo, H.J.;Choi, B.H.
    • Nuclear Engineering and Technology
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    • v.19 no.2
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    • pp.115-121
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    • 1987
  • A high voltage stabilization system for the SNU 1.5MV Tandem Van do Graaff accelerator was set up and its operational characteristics were examined and optimized. The optimum parameters of beam transport system were experimentally determined, and under the proper condition the accelerated proton beam current of 350nA was obtained at the target chamber. Without the high voltage stabilization the observed magnitude of voltage fluctuation was $\Delta$V/ V=5.2$\times$10$^{-3}$ without ion beam and 7.2$\times$10$^{-3}$ with ion beam, respectively, and its apparent ripple frequency for voltage fluctuations was about 3Hz or less. Through the optimized operation of the high voltage stabilization system, the terminal voltage fluctuation was reduced to $\Delta$V/V=2.45$\times$10$^{-4}$ and the energy stability with $\Delta$E/E=2.44$\times$10$^{-4}$ was steadily maintained at the 247.3kV terminal voltage, and the stabilization factor was deduced to be 29.4.

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A Study on Effect of Urea-SCR Aftertreatment System upon Exhaust Emissions in a LPG Steam Boiler (LPG 증기보일러의 배기 배출물에 미치는 요소-SCR 후처리 시스템의 영향에 관한 연구)

  • Bae, Myung-Whan;Song, Byung-Ho
    • Transactions of the Korean Society of Automotive Engineers
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    • v.22 no.3
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    • pp.1-11
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    • 2014
  • The aim of this study is to investigate the effect of SCR reactor on the exhaust emissions characteristics in order to develop a urea-SCR aftertreatment system for reducing $NO_x$ emissions. The experiments are conducted by using a flue tube LPG steam boiler with the urea-SCR aftertreatment system. The urea-SCR aftertreatment system utilizes the ammonia converted from 17% aqueous urea solution injected in front of SCR catalyst as a reducing agent for reducing $NO_x$ emissions. The equivalence ratio, urea injection amount, ammonia slip and $NO_x$ conversion efficiency relative to boiler load are applied to discuss the experimental results. In this experiment, the average equivalence ratio is calculated by changing only the fuel consumption rate while the intake air amount is constantly fixed at $25,957.11cm^3/sec$. The average equivalence ratios are 1.38, 1.11, 0.81 and 0.57 when boiler loads are 100, 80, 60 and 40%. The $NO_x$ conversion efficiency is raised with increasing urea injection amount, and $NH_3$ slip is also boosted at the same time. Consequently, the $NO_x$ conversion efficiency relative to boiler load should be examined in combination with urea injection amount and $NH_3$ slip. The results are calculated by 89, 85, 77 and 79% for the boiler loads of 100, 80, 60 and 40%. The appropriate amount of urea injection for the respective boiler load can be not discussed by only $NO_x$ emissions, and should be determined by considering the $NO_x$ conversion efficiency, $NH_3$ slip and reactive activation temperature simultaneously. In this study, the urea amounts of 230, 235, 233 and 231 mg/min are injected at the boiler loads of 100, 80, 60 and 40%, and the final $NH_3$ slips are measured by 8.48, 5.58, 11.97 and 11.34 ppm at the same conditions. THC emission is affected by the SCR reactor under other experimental conditions except 100% engine load, and CO emission at only 40% engine load. The rest of exhaust emissions are not affected by the SCR reactor under all experimental conditions.

SHEAR BOND STRENGTH OF "ONE-BOTTLE ADHESIVE" SYSTEM IN PRIMARY DENTIN. (One-Bottle 상아질 결합제의 유치 상아질에 대한 전단 결합 강도에 관한 연구)

  • Kim, Jong-Bin;Kim, Jong-Soo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.27 no.3
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    • pp.444-456
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    • 2000
  • To test the shear bond strength of a new "one-bottle adhesive" system to primary dentin two commercially available one-bottle adhesives (Prime & Bond NT, Single bond) and conventional three step system(Scotchbond Multi-Purpose Plus) were included for comparison. And We observe the interfacial morphology by scanning electron microscope. 90 primary molar teeth were embedded in acrylic and buccal and lingual surface were polished to 320 grit to create standardized dentin surface for testing. After bonding of composite resin to sample surfaces according to the manufacturer s direction and 1000 times thermocycling in dwell time 30 second, Shear bond strengths of adhesives to dentin were determined using universal testing machine and analyzed by ANOVA test. Another groups of specimens were treated by hydrochloric acid to secure the resin only and those tags were evaluated under SEM for their length and forms and the morphology of the bonding sites were also observed. The result are as follows. 1. Group I(Prime & Bond NT) showed higher shear bond strength than group iI(Single Bond) and III(Scotchbond Multi Purpose Plus) but no statistically significant difference was founded between groups(p>.05). 2. Relating long resin tags of $70-120{\mu}m$ were observed in samples of all groups under SEM. We could observed hybrid layer, resin tag and many lateral branches in every group. But, we observed in group III rare lateral branched than other two group and discontinuous hybrid layer.

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Korea's Optimal Basket Exchange Rate : Thoughts on the Proper Operation of the Market Average Rate Regime (우리나라의 적정(適正)바스켓환율(換率) : 시장평균환율제도(市場平均換率制度)의 운용기준(運用基準) 모색(模索))

  • Oum, Bong-sung
    • KDI Journal of Economic Policy
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    • v.12 no.1
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    • pp.111-125
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    • 1990
  • For the last several years, considerable criticism has been leveled against Korea's exchange rate management. While Korea was designated a currency manipulator by the U.S., domestically it is often complained that the won/dollar rate did not adequately reflect changes in Korea's export competitiveness and fluctuations in the exchange rates of major currencies. In view of this situation, Korea changed its exchange regime at the beginning of March this year from the dual currency basket system to a more flexible one, called a "market average rate regime". Under this new regime, the won rate is determined in the exchange market based upon the supply of and demand for foreign exchange and is allowed to freely fluctuate each day within a + 0.4 % range. This paper, first, seeks to evaluate Korea's exchange rate management under the dual basket regime of the 1980s, and then to construct an optimal currency basket for the won which could provide a proper indicator for exchange market intervention under the new market average rate regime. The analysis of fluctuations in the real effective exchange rate (REER) of the won indicates that the won rates in the 1980s failed not only to offset changes in relative prices between home and trading partner countries, but also to properly respond to variations in major exchange rates as further evidenced by sizable fluctuations in the nominal effective rates of the won. In other words, the currency basket regime which was adopted in 1980 for the stabilization of the REER of the won has not been operated properly, mainly because authorities often resorted to policy considerations in determining the won's rate. In the second part of the paper, an optimal currency basket for Korea is constructed, designed to minimize the fluctuations in the REER of the won without including policy considerations as a factor. It is recognized, however, that both domestic and foreign price data are not available immediately for the calculation of the REER. For this problem, the approach suggested by Lipschitz (1980) is followed, in which optimal weights for currencies in the basket are determined based upon the past correlation between price and exchange rates. When the optimal basket is applied to Korea since the mid-80s, it is found that the REER of the won could have been much more stable than it actually was. We also argue for the use of variable weights rather than fixed ones, which would be determined by the changing relationship between exchange rates and relative prices. The optimal basket, and the optimal basket exchange rate based on that basket, could provide an important medium- or long-term reference for proper exchange market intervention under the market average rate regime, together with other factors, such as developments in the current account balance and changes in productivity.

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Emission of Green House Gases in the Agricultural Environment -1. The Cropping System and Emission of the Green House Gases-CO2, CH4, N2O)-under Different Cropping System (농작물(農作物) 재배환경(栽培環境)과 지구온난화(地球溫暖化) 원인(原因)가스 발생(發生) -1. 답전전환시(畓田轉換時) 작부체계(作付體系)와 지구온난원인기체(地球溫暖原因氣體) -이산화탄소(二酸化炭素), 메탄, 아산화질소(亞酸化窒素)- 발생(發生))

  • Lee, Sang-Kyu;Suh, Jang-Sun
    • Korean Journal of Soil Science and Fertilizer
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    • v.26 no.1
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    • pp.49-56
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    • 1993
  • The net flux of global green house gases such as carbon dioxide($CO_2$), methane($CH_4$), and nitrous oxide($N_2O$) emitted from the rotation of paddy-upland soil during growing sesaon under different cropping system was determined. The results obtained were summarized as follows : 1. The net flux of $CO_2$ during the growing season was the highest from continuous cultivation of rice but the lowest from rotation cultivation of rice-soybean. Under the different cropping system the highst emission was from soil of continuous cultivation of rice, but the lowest from converted system. 2. The net emission of methane was the highest from the sold of continuous cultivation of rice, but the flux was remarkably decreased by differing the cropping system. 3. $N_2O$ was emitted greatly from the every two year rotation of potato-chinese cabbage and the next rank was from continuous cultivation of rice, but was decreased notably from rotation cultivation of rice-soybean and potato-chinese cabbage under rotation of paddy-upland cropping system. 4. The ratio of oxygen and carbon dioxide in the soil air was much different with glowing season, the ratio was varied with 4~10 percents for oxygen and 1~22 percents for carbon dioxide. The ratio of carbon dioxide was dozens or hundreds times to that of air, and the variation was very high also. 5. The emission of global green house gases such as carbon dioxide, methane and nitrous oxide was affected by the moisture, temperature and nutrients of soils and the growth period of crops.

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A STUDY ON GEOMETRIC COMPARISON OF FOUR INTERCHANGEABLE IMPLANT PROSTHETIC RETAINING SCREWS AND MEASUREMENT OF LOOSENING TORGUE (호환 가능한 임플랜트 보철용 유지 나사들의 형태 비교와 풀림 회전력의 측정에 관한 연구)

  • Cho, Su-Mi;Lim, Ju-Hwan;Cho, In-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.36 no.3
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    • pp.468-482
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    • 1998
  • Since the concept of osseointegration was introduced by Branemark of Sweden, dental implants have been used for various dental prosthetic treatments. The survival rate of dental implant is likely to be closely related to the total biomechanical role of each component of implant system. The use of interchangeable component is very attractive for dental practitioners because such an approach would save treatment cost, flexibility of prosthetic treatment options as well as conveniences. Therefore, the use of interchangeable implant system has been increasing without scientific assessment of safety and efficacy of various interchangeable implant system. The purpose of this study, therefore, were to compare the geometric characteristic of four interchangeable dental implant screws and the loosening torque of these screws. Four types of dental implant screws tested in this study were Nobelpharma, 3i, Impla-med, Restore. Four screws each of the test specimens were subjected for scanning electron microscopic examinations under the same condition and a 35x magnified standard SEM picture was objected from each test specimen using JSM-5200 scanning microscope. From each of the SEM pictures, eight parameters. i.e., diameter of screw head. screw length, thread pitch, major diameter. neck diameter, neck length, crest width and root width were determined using a caliper. The measurement for each parameters were then corrected for their magnification factor. The loosening torque were also determined by using a torque gauge. All of the measurements were statistically analyzed by ANOVA test and multiple range test. Statistical significance was set in advance at the probability level of less than 0.05. All analyses were done with SPSS software for the personal computer. The conclusion obtained from this studies were summarized as the following; 1. No statistically significances were noted in the thread pitch. and crest width in the four screws, and in the case of major diameter, the Impla-med screw was significantly smaller than the other three screws (p<0.05). Therefore, four implant bolts could be physically inserted in a abutment nuts. 2. The diameter of screw head was decreased in the order of Restore, 3i, Nobelpharma, Impla-med screws and the length of screws were decreased in the order of 3i, Restore, Nobelpharma and Impla-med. The diameter of neck was decreased in the order of Impla-med, Restore. Nobelpharma, 3i screws. The differences of each of these parameters were statistically significant (p<0.05). The width of root of screws were decreased in the order of Nobelpharma, Impla-med, Restore and 3i. The differences among Nobelpharma and Impla-med. Restore and 3i were statistically significant (p<0.05). 3. When the screws were loosening 1, 3, 4 and 5 times, the loosening torque for Impla-med and 3i screws were significantly higher than that of Nobelpharma or Restore screws (p<0.05). However, when statistically smaller than that of 3i, Restore or Nobelpharma screws(p<0.05).

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