• Title/Summary/Keyword: unclear industry

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Identification of Major BIM-applicable Tasks with Contribution to Achieving Objectives and Expected Benefit in Construction Stage: Focused on the Case of Public Apartment Housing Projects (목표달성기여도와 예상적용효과에 의한 시공단계 BIM 주요 업무 도출 - 공공부문 공동주택 건설사업 사례를 중심으로 -)

  • Song, Sanghoon;Bang, Jong-Dae;Sohn, Jeong-Rak
    • Journal of KIBIM
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    • v.9 no.3
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    • pp.41-53
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    • 2019
  • As a central part in smart construction, BIM has been rapidly spread in construction industry at large. However, the level of applying BIM in construction stage is still relatively lower than that in design stage due to unclear application method, inadequate design BIM model, technical faults of BIM itself, etc. Under these circumstances, public owners inevitably need to adjust the scope and pace in BIM application considering their internal support and capabilities of contractors. This study aims to suggest major BIM-applicable tasks during construction stage in the process of establishing gradual long-term and short-term introduction strategy for public apartment housing projects. Those major tasks were identified with the combination of the importance of tasks and the future benefits of BIM using IPA method. To do so, the degrees of contribution to achieving objectives in construction, current task execution, and communication requirement were investigated by internal site managers. On the other hand, the expected benefits and current level of using BIM were assessed by BIM experts. Among operational tasks by phases, design review, construction plan review, making as-built drawing, etc. were categorized as major tasks. In addition, progress control, regular meeting, master schedule development, work inspection, on-site quality check, etc. were also drawn as major tasks by management areas. The results of this study will provide the useful reference for owners concerned about the introduction of new technologies.

Revising the Archives Law to Boost Commercial Records Facilities Industry : Issues & Tasks (민간시설 활성화를 위한 공공기록법 개정(안) : 쟁점과 과제)

  • Lee, So-Yeon
    • The Korean Journal of Archival Studies
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    • no.47
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    • pp.197-225
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    • 2016
  • Korean archival community had continuously dealt with attempts at weakening the core of records and archives principles in the name of deregulation. In 2015, Korean government announced revisions of the Archives Law in order to boost uses of commercial records facilities by public institutions. As key concepts were unclear and understandings among stake-holders varied, a considerable degree of chaos and anxiety aroused. The amendment itself was held at National Assembly. The unresolved disputes rested, however, waiting for another attempt of similar nature. As the recognition propelled this paper, it aimed at reviewing major contending arguments and proposing future actions.

Improvement of Safety Management and Plan by Comparison Analysis of Construction Technology Promotion Act(CTPA) and Occupational Safety and Health Act(OSHA) in Construction Field (건설기술진흥법과 산업안전보건법 비교분석을 통한 건설업 안전관리 및 계획의 개선방안)

  • Kim, Si Ouk;Yoon, Young Geun;Oh, Tae Keun
    • Journal of the Korean Society of Safety
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    • v.36 no.4
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    • pp.37-46
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    • 2021
  • According to the Korean Statistical Information Service, the number of fatal occupational accidents per 100,000 workers is the highest in Korea, among all the OECD countries. The safety of construction workers is managed by the construction technology promotion act (CTPA) and the occupational safety and health act (OHSA). A review of the current safety management laws is required to improve them for the construction industry, where the numbers of accidents and deaths are constantly increasing. Accordingly, the aim of this study was to identify the problems in unclear business areas through comparison and analysis of the CTPA and OHSA guidelines and establish effective site-dependent construction safety management plans. The overlapping safety and health management terms and tasks of organizations were derived along with identifying the overlapping items of the safety management and hazard and risk prevention plans. Based on these results, several improvements for the design stage, safety cost, and safety education have been suggested in this paper. In addition, an improved model based on the integration and an optimized compromise between these two laws for safety management in areas where many accidents have occurred in recent years has been reported here.

Inhibition of adipogenesis and melanogenesis by methanol extract of Codium fragile (Suringar) Hariot in 3T3-L1 adipocytes and B16F10 melanocytes (3T3-L1 및 B16F10 세포에서 청각 메탄올 추출물에 의한 지방 세포 분화 및 멜라닌 생성의 억제 효과)

  • Choi, Eun-Ok;Choi, Yung Hyun;Hwang, Hye-Jin
    • Journal of Marine Bioscience and Biotechnology
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    • v.13 no.1
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    • pp.1-9
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    • 2021
  • Codium fragile (Suringar) Hariot, a green alga of the Codiales family, has been reported to have several bioactive properties, including antioxidant and anti-inflammatory properties. However, its antiobesity and whitening effects and their underlying mechanisms are unclear. This study aimed to evaluate the antiobesity and melanogenesis inhibitory effects of C. fragile using methanol extracts of C. fragile (MECF). The results of this study revealed that MECF inhibited the accumulation of lipid droplets and triacylglycerol in differentiated 3T3-L1 adipocytes, which was associated with the inhibition of the expression of adipogenesis-related transcription factors, such as peroxisome proliferator-activated receptor γ, CCAAT/enhancer-binding protein-α (C/EBPα), and C/EBPβ, which function as the key regulators of adipogenesis. Also, MECF reduced tyrosinase activity and melanin content in B16F10 cells as well as the expression of tyrosinase, tyrosinase-related protein-1 (TRP-1), TRP-2, and microphthalmia-related transcription factor in the presence of α-melanocyte-stimulating hormone. Taken together, our findings suggest that the extract of C. fragile could be considered a promising functional ingredient for the prevention and treatment of obesity and skin pigmentation in the food and cosmetic industry.

A Discussion on the Legal Definition and Legislation Methods of Drone Taxis (드론 택시의 법적 정의 및 법제화 방안 논의)

  • Choi, Ja-Seong;Baek, Jeong-seon;Hwang, Ho-Won
    • Journal of Advanced Navigation Technology
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    • v.24 no.6
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    • pp.491-499
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    • 2020
  • There are policies that foster the drone industry, which either put a legal precedent on drones through the "Drone Act" or grant a delay or exemption in applying the safety measures of "the Aviation Safety Act". Yet, the definition of a drone is unclear, requiring further discussion on commercial usage. Therefore, we have studied cases domestically and abroad, and also analyzed issues with the current aviation legislation. It was found that a drone is defined as "an unmanned aircraft where a pilot is not on board, and its net weight is 150 kg or less". However, there are several issues, such as that a drone taxi requires a pilot on board, and its weight is 150 kg or more. Thus, we propose to define a drone as "an unmanned aerial vehicle (provided, that its own net weight should be 300 kg or under, or not be limited to weight) under Article 2 (3) of the "Aviation Security Act" as prescribed by Ordinance of the Ministry of Land, Infrastructure, and Transport, which operates either by remote, automatically, or autonomously; or an unmanned aircraft under Article 2 (6) of the "Aviation Security Act".

A Legal Study on The Act Bill for Establishing The Game User Committee

  • Kyen, Seung-Yup
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.3
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    • pp.165-171
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    • 2022
  • In this paper, we suggest the Measures to improve the Act Bill for establishing the Game User Committee. The Act Bill has a lot of problems which are violations of criminal legalism due to unclear terms in administrative punishment and violations of The Human Right enjoying freedom of occupation and guaranting property due to not defining provisisons about The Duty of Confidentiality or The Legal Fiction as Public Officials for Purposes of Applying Penalty Provisions. also the duplicate regulations in the Act Bill disrupt game industry development. we have three results that were derived through analysis of Prior studies and precedents. The First is to define details of special reasons in enforcement ordinance and enforcement regulations. The Second is to define The Duty of Confidentiality or The Legal Fiction as Public Officials for Purposes of Applying Penalty Provisions in the act bill. The Third is to address managing the random reward items in the Game Rating and Administration Committee or is to give game user advance notice about the Comntent Dispute Mediation system.

Construction and Analysis of Food-Grade Lactobacillus kefiranofaciens β-Galactosidase Overexpression System

  • He, Xi;Luan, MingJian;Han, Ning;Wang, Ting;Zhao, Xiangzhong;Yao, Yanyan
    • Journal of Microbiology and Biotechnology
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    • v.31 no.4
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    • pp.550-558
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    • 2021
  • Lactobacillus kefiranofaciens contains two types of β-galactosidase, LacLM and LacZ, belonging to different glycoside hydrolase families. The difference in function between them has been unclear so far for practical application. In this study, LacLM and LacZ from L. kefiranofaciens ATCC51647 were cloned into constitutive lactobacillal expression vector pMG36e, respectively. Furtherly, pMG36n-lacs was constructed from pMG36e-lacs by replacing erythromycin with nisin as selective marker for food-grade expressing systems in Lactobacillus plantarum WCFS1, designated recombinant LacLM and LacZ respectively. The results from hydrolysis of o-nitrophenyl-β-galactopyranoside (ONPG) showed that the β-galactosidases activity of the recombinant LacLM and LacZ was 1460% and 670% higher than that of the original L. kefiranofaciens. Moreover, the lactose hydrolytic activity of recombinant LacLM was higher than that of LacZ in milk. Nevertheless, compare to LacZ, in 25% lactose solution the galacto-oligosaccharides (GOS) production of recombinant LacLM was lower. Therefore, two β-galactopyranosides could play different roles in carbohydrate metabolism of L. kefiranofaciens. In addition, the maximal growth rate of two recombinant strains were evaluated with different temperature level and nisin concentration in fermentation assay for practical purpose. The results displayed that 37℃ and 20-40 U/ml nisin were the optimal fermentation conditions for the growth of recombinant β-galactosidase strains. Altogether the food-grade Expression system of recombinant β-galactosidase was feasible for applications in the food and dairy industry.

Isolation of feline panleukopenia virus from Yanji of China and molecular epidemiology from 2021 to 2022

  • Haowen Xue;Chunyi Hu;Haoyuan Ma;Yanhao Song;Kunru Zhu;Jingfeng Fu;Biying Mu;Xu Gao
    • Journal of Veterinary Science
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    • v.24 no.2
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    • pp.29.1-29.12
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    • 2023
  • Background: Feline panleukopenia virus (FPV) is a widespread and highly infectious pathogen in cats with a high mortality rate. Although Yanji has a developed cat breeding industry, the variation of FPV locally is still unclear. Objectives: This study aimed to isolate and investigate the epidemiology of FPV in Yanji between 2021 and 2022. Methods: A strain of FPV was isolated from F81 cells. Cats suspected of FPV infection (n = 80) between 2021 and 2022 from Yanji were enrolled in this study. The capsid protein 2 (VP2) of FPV was amplified. It was cloned into the pMD-19T vector and transformed into a competent Escherichia coli strain. The positive colonies were analyzed via VP2 Sanger sequencing. A phylogenetic analysis based on a VP2 coding sequence was performed to identify the genetic relationships between the strains. Results: An FPV strain named YBYJ-1 was successfully isolated. The virus diameter was approximately 20-24 nm, 50% tissue culture infectious dose = 1 × 10-4.94/mL, which caused cytopathic effect in F81 cells. The epidemiological survey from 2021 to 2022 showed that 27 of the 80 samples were FPV-positive. Additionally, three strains positive for CPV-2c were unexpectedly found. Phylogenetic analysis showed that most of the 27 FPV strains belonged to the same group, and no mutations were found in the critical amino acids. Conclusions: A local FPV strain named YBYJ-1 was successfully isolated. There was no critical mutation in FPV in Yanji, but some cases with CPV-2c infected cats were identified.

A study on the regulation of the similar transmission service of digital music (디지털 음원 유사전송 서비스의 규제 방안 연구)

  • Yu, Seung-Jun;Lee, Hwan-soo
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.8 no.4
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    • pp.151-160
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    • 2018
  • The development of digital technology and the Internet has brought about a great change in the content industry. In order to keep pace with these changes, the copyright law has undergone several revisions, and the concept of "digital sound transmission" was introduced in the 2006 revision. However, in the current law, digital audio transmission is problematic in that the criteria for distinguishing between broadcasting and transmission is abstract and unclear. This ambiguity makes it difficult to judge the legal status of new music webcasting service such as "Free Litsen". Although these services are positioned as digital audion transmission, they have created a new concept of pseudo transmission because of its similarity to the audio transmission in its convenience and utility. These problems stem from the imbalance of between the development of technology and the legal system, so the change of the legal system is inevitable. Thus, this study discusses US copyright law and related cases, and then suggests solutions for pseudo transmission problems. This study suggests legislative criteria for pseudo transmission problems and legislative measures that can reduce the actual damage to the music market.

Cadmium exposure impairs porcine embryonic development by inducing oxidative stress and mitochondrial dysfunction

  • Min Ju Kim;Se‑Been Jeon;Hyo‑Gu Kang;Bong‑Seok Song;Bo‑Woong Sim;Sun‑Uk Kim;Pil‑Soo Jeong;Seong‑Keun Cho
    • Journal of Animal Reproduction and Biotechnology
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    • v.39 no.1
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    • pp.48-57
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    • 2024
  • Background: Cadmium (Cd) is toxic heavy metal that accumulates in organisms after passing through their respiratory and digestive tracts. Although several studies have reported the toxic effects of Cd exposure on human health, its role in embryonic development during preimplantation stage remains unclear. We investigated the effects of Cd on porcine embryonic development and elucidated the mechanism. Methods: We cultured parthenogenetic embryos in media treated with 0, 20, 40, or 60 µM Cd for 6 days and evaluated the rates of cleavage and blastocyst formation. To investigate the mechanism of Cd toxicity, we examined intracellular reactive oxygen species (ROS) and glutathione (GSH) levels. Moreover, we examined mitochondrial content, membrane potential, and ROS. Results: Cleavage and blastocyst formation rates began to decrease significantly in the 40 µM Cd group compared with the control. During post-blastulation, development was significantly delayed in the Cd group. Cd exposure significantly decreased cell number and increased apoptosis rate compared with the control. Embryos exposed to Cd had significantly higher ROS and lower GSH levels, as well as lower expression of antioxidant enzymes, compared with the control. Moreover, embryos exposed to Cd exhibited a significant decrease in mitochondrial content, mitochondrial membrane potential, and expression of mitochondrial genes and an increase in mitochondrial ROS compared to the control. Conclusions: We demonstrated that Cd exposure impairs porcine embryonic development by inducing oxidative stress and mitochondrial dysfunction. Our findings provide insights into the toxicity of Cd exposure on mammalian embryonic development and highlight the importance of preventing Cd pollution.