• Title/Summary/Keyword: two sample testing

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Development of Triaxial Cells Operable with In Situ X-ray CT for Hydro-Mechanical Laboratory Testing of Rocks (원위치 X-ray CT 촬영이 가능한 암석의 수리-역학 실험용 삼축셀 개발)

  • Zhuang, Li;Yeom, Sun;Shin, Hyu-Soung
    • Journal of the Korean Geotechnical Society
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    • v.36 no.9
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    • pp.45-55
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    • 2020
  • X-ray computed tomography (CT) is very useful for the quantitative evaluation of internal structures, particularly defects in rock samples, such as pores and fractures. In situ CT allows 3D imaging of a sample subjected to various external treatments such as loading and therefore enables observation of changes that occur during the loading process. We reviewed state-of-the-art of in situ CT applications for geomaterials. Two triaxial cells made using relatively low density but high strength materials were developed aimed at in situ CT scanning during hydro-mechanical laboratory testing of rocks. Preliminary results for in situ CT imaging of granite and sandstone samples with diameters ranging from 25 mm to 50 mm show a resolution range of 34~105 ㎛ per pixel pitch, indicating the feasibility of in situ CT observations for internal structural changes in rocks at the micrometer scale. Potassium iodide solution was found to improve the image contrast, and can be used as an injection fluid for hydro-mechanical testing combined with in situ CT scanning.

Necessity of high-performance liquid chromatography validation in good laboratory practice systems (비임상시험관리기준 시스템에서 고성능액체크로마토그래피 분석법 정확도 검증의 필요성)

  • Su Bin Yang;Changyul Kim
    • Journal of the Korean Applied Science and Technology
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    • v.41 no.2
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    • pp.172-187
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    • 2024
  • In good laboratory practice (GLP), analytical method validation prior to toxicity testing is important in terms of concentration setting and sample preparation. The testing agency performed validation of the two requested test substances using high-performance liquid chromatography (HPLC), and as a result, the analysis satisfied the criteria for specificity, system suitability, linearity, intra-day reproducibility, homogeneity, stability, concentration analysis, and quality control. The method was established and validated. However, the content of standard substances in the test report of the requesting institution was found to be 1.34 and 1.17 times higher than the results of the testing institution, confirming that deriving results through validation of analysis methods suitable for GLP is important in terms of securing reliability and stability.

A Study on Tests for the Parallelism of Regression Lines Against Ordered Alternatives (순서대립가설에 대한 회귀직선 평행성 검정에 관한 연구)

  • Song, Mun-Seop;Jo, Sin-Seop;Lee, Jae-Jun;Sin, Bong-Seop
    • Journal of Korean Society for Quality Management
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    • v.21 no.2
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    • pp.162-169
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    • 1993
  • For the problem of testing the parallelism of several regression lines against ordered alternatives, two test statistics and proposed and examined. The proposed statistics are linear combinations of robust estimators of slope parameters, which are modifications of the Adichie (1976) test based on scores. The asymptotic null variances of the proposed states tics are estimated by the kernel density estimation methods. The proposed tests are compared with the Adichie's test in terms of asymptotic relative efficiency and small-sample powers.

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The Eccentric Properties of the Chi-Squared Test with Yates' Continuity Correction in Extremely Unbalanced 2×2 Contingency Table

  • Kang, Seung-Ho;Kwon, Tae-Hyuk
    • The Korean Journal of Applied Statistics
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    • v.23 no.4
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    • pp.777-781
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    • 2010
  • Yates' continuity correction of the chi-squared test for testing the homogeneity of two binomial proportions in $2{\times}2$ contingency tables is developed to lower the value of the test statistic slightly. The effect of continuity correction is expected to decrease as the sample size increases. However, in extremely unbalanced $2{\times}2$ contingency tables, we find some cases where the effect of continuity correction is eccentric and is larger than expected. In such cases, we conclude that the chi-squared test with continuity correction should not be employed as a test statistic in both asymptotic tests and exact tests.

Estimation for the Rayleigh distribution based on Type I hybrid censored sample

  • Kwon, Byongwon;Lee, Kyeongjun;Cho, Youngseuk
    • Journal of the Korean Data and Information Science Society
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    • v.25 no.2
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    • pp.431-438
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    • 2014
  • Type I hybrid censoring scheme is the combination of the Type I and Type II censoring scheme introduced by Epstein (1954). Epstein considered a hybrid censoring sampling scheme in which the life testing experiment is terminated at a random time $T^*$ which is the time that happens rst among the following two; time of the kth unit is observed or time of the experiment length set in advance. The likelihood function of this scheme from the Rayleigh distribution cannot be solved in a explicit solution and thus we approximate the function by the Taylor series expansion. In this process, we propose four dierent methods of expansion skill.

Cross platform classification of microarrays by rank comparison

  • Lee, Sunho
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.2
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    • pp.475-486
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    • 2015
  • Mining the microarray data accumulated in the public data repositories can save experimental cost and time and provide valuable biomedical information. Big data analysis pooling multiple data sets increases statistical power, improves the reliability of the results, and reduces the specific bias of the individual study. However, integrating several data sets from different studies is needed to deal with many problems. In this study, I limited the focus to the cross platform classification that the platform of a testing sample is different from the platform of a training set, and suggested a simple classification method based on rank. This method is compared with the diagonal linear discriminant analysis, k nearest neighbor method and support vector machine using the cross platform real example data sets of two cancers.

Testing microsatellite loci and preliminary genetic study for Eurasian otter in South Korea

  • Jo, Yeong-Seok;Won, Chang-Man;Jung, Jongwoo
    • Journal of Species Research
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    • v.1 no.2
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    • pp.240-248
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    • 2012
  • We used a non-invasive technique with microsatellite primers to investigate genetic variation among Eurasian otters Lutra lutra in eastern South Korea. We collected twenty two otter spraints in January and six in August 2008. We used spraints from five dead otters from five different river systems for the present genetic analysis. We extracted DNA from 20 spraints from the January sample. Ten microsatellite primers (Lut435, Lut453, Lut457, Lut604, Lut615, Lut701, Lut715, Lut717, Lut733, and Lut832) for Eurasian otters were tested, and four loci were successfully amplified for further analyses. The results of genotyping the otter population with microsatellite loci lead to the identification of 9 individuals from the Ungokcheon Stream. The Ungokcheon population also showed a genetic structure represented by the Hardy-Weinberg equilibrium.

Goodness-of-fit tests based on generalized Lorenz curve for progressively Type II censored data from a location-scale distributions

  • Lee, Wonhee;Lee, Kyeongjun
    • Communications for Statistical Applications and Methods
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    • v.26 no.2
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    • pp.191-203
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    • 2019
  • The problem of examining how well an assumed distribution fits the data of a sample is of significant and must be examined prior to any inferential process. The observed failure time data of items are often not wholly available in reliability and life-testing studies. Lowering the expense and period associated with tests is important in statistical tests with censored data. Goodness-of-fit tests for perfect data can no longer be used when the observed failure time data are progressive Type II censored (PC) data. Therefore, we propose goodness-of-fit test statistics and a graphical method based on generalized Lorenz curve for PC data from a location-scale distribution. The power of the proposed tests is then assessed through Monte Carlo simulations. Finally, we analyzed two real data set for illustrative purposes.

Validation of a Needs Assessment Tool for Case Management in Korean Medical Aid Beneficiaries (의료급여수급권자의 사례관리 요구측정도구의 타당도와 신뢰도 검증)

  • Ahn, Yang-Heui;Kim, Eui-Sook;Ham, Ok-Kyung;Kim, Soo-Hyun;Kim, Soon-Ok;Song, Myung-Kyung
    • Journal of Korean Academy of Nursing
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    • v.42 no.4
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    • pp.549-558
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    • 2012
  • Purpose: The purpose of this study was to validate the Needs Assessment Tool for Case Management (NATCM) for use with Korean medical aid beneficiaries. Methods: Psychometric testing was performed with a sample of 645 Korean medical aid beneficiaries, which included 41 beneficiaries who were selected using proportional sampling method, to examine intraclass correlation coefficients (ICC). Data were evaluated using item analyses, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), Cronbach's alpha, and ICC. Results: Through psychometric testing the final version of NATCM was found to consist of two subscales: 1) Appropriateness of Health Care Utilization (5 items) and 2) Self Care Ability (6 items). The two subscale model was validated by CFA (RMSEA=.08, GFI=.97, and CFI=.93). Internal consistency measured by Cronbach's alpha was .82, and subscale reliability ranged from .79 to .84. The ICC of the NATCM between case managers was .73 and between case managers and health care professionals. .82. Conclusion: This study suggests that the final version of NATCM is a brief, reliable, and valid instrument to measure needs of Korean medical aid beneficiaries. Therefore, the NATCM can be effectively utilized as an important needs assessment as well as outcome evaluation tool for case management programs in Korea.

Microstructure and Mechanical Properties of AA6061/AA5052/AA6061 Complex Sheet Fabricated by Cold-Roll Bonding Process (냉간압연접합법에 의해 제조된 AA6061/AA5052/AA6061 복합판재의 미세조직 및 기계적 성질)

  • Hwang, Ju-Yeon;Lee, Seong-Hee
    • Korean Journal of Materials Research
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    • v.29 no.6
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    • pp.392-397
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    • 2019
  • A cold roll-bonding process is applied to fabricate an AA6061/AA5052/AA6061 three-layer clad sheet. Two AA6061 and one AA5052 sheets of 2 mm thickness, 40 mm width, and 300 mm length are stacked, with the AA5052 sheet located in the center. After surface treatment such as degreasing and wire brushing, sample is reduced to a thickness of 1.5 mm by multi-pass cold rolling. The rolling is performed at ambient temperature without lubricant using a 2-high mill with a roll diameter of 400 mm at rolling speed of 6.0 m/sec. The roll bonded AA6061/AA5052/AA6061 complex sheet is then hardened by natural aging(T4) and artificial aging(T6) treatments. The microstructures of the as-roll bonded and age-hardened Al complex sheets are revealed by optical microscopy; the mechanical properties are investigated by tensile testing and hardness testing. After rolling, the roll-bonded AA6061/AA5052/AA6061 sheets show a typical deformation structure in which grains are elongated in the rolling direction. However, after T4 and T6 aging treatment, there is a recrystallization structure consisting of coarse equiaxed grains in both AA5052 and AA6061 sheets. The as roll-bonded specimen shows a sandwich structure in which an AA5052 sheet is inserted into two AA6061 sheets with higher hardness. However, after T4 and T6 aging treatment, there is a different sandwich structure in which the hardness of the upper and lower layers of the AA6061 sheets is higher than that of the center of the AA5052 sheet. The strength values of the T4 and T6 age-treated specimens are found to increase by 1.3 and 1.4 times, respectively, compared to that value of the starting material.