• 한국자기공명학회논문지
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• 제27권4호
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• pp.23-27
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• 2023

Hoxc, or the Homeobox C cluster, is a group of genes that play a crucial role in embryonic development, particularly in patterning the body along the anterior-posterior axis. These genes encode transcription factors, which are proteins that bind to DNA and regulate the expression of other genes. Hoxc9 is specifically involved in the development of the skeletal system, nervous system, and adipose tissue. Hoxc9 overexpression has been linked to the development of various cancers such as leukemia and breast cancer. Here, we assigned the chemical shifts Hoxc9 DNA binding domain (DBD) using heteronuclear NMR techniques. The helical regions of Hoxc9 DBD correspond to the residues T200 - F213 (Helix I), T218 - L229 (Helix II), and T232 - K249 (Helix III). Our result would be helpful for studing the molecular interactions of the Hoxc9 DBD and other proteins.

• Journal of Contemporary Eastern Asia
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• 제7권2호
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• pp.17-27
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• 2008

• Journal of Contemporary Eastern Asia
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• 제11권2호
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• pp.1-12
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• 2012

• Journal of Contemporary Eastern Asia
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• 제10권1호
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• pp.25-42
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• 2011

• Journal of Contemporary Eastern Asia
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• 제8권2호
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• pp.45-62
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• 2009

• Journal of Contemporary Eastern Asia
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• 제13권1호
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• pp.19-37
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• 2014

In an attempt to develop comprehensive evidence-based methods for evaluation of the R&D performance of cross-disciplinary projects, a joint bibliometric analysis of patents and publications was performed for two industry-university-government collaborative projects aimed at commercialization: Hokkaido University Research & Business Park Project (2003-2007; 63 inventors; 176 patents; 853 papers), and Matching Program for Innovations in Future Drug Discovery and Medical Care - phase I (2006-2010; 46 inventors; 235 patents; 733 papers). Besides the simple output indicators (for five years period), and citations (from the publication date to the end of 2012), science maps based on the network analysis of words and co-authorship relations were generated to identify the prominent research themes and teams. Our joint analysis of publications and patents yields objective and mutually complementing information, which provides better insights on research and commercialization performance of the large-scale projects. Hence, such analysis has potential for use in the industry-university project's performance evaluation.

• STI Policy Review
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• 제8권1호
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• pp.23-40
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• 2017

This article provides a comprehensive review of the entrepreneurial university concept and its place and role in the triple helix of university, industry, and government. This is increasingly important because stake-holders' expectations towards universities are growing; this growth in turn leads to increased pressure on universities to move beyond their traditional roles and models towards taking responsibility for economic development, large scale basic education and targeted further education and the development of value from research. These expectations provide opportunities for universities, but impose threats on the existing models and practices. It further elaborates on implications for university management, departments, faculty members and supporting organizations. Moreover it reflects on the meaning of the entrepreneurial university for stakeholders, i.e., university boards, regional and national policy and administrative bodies, funding agencies, the business community, university ranking institutions and the global university community overall. Recent literature on entrepreneurial universities is incomplete and mostly focused on the commercialization of research, technology transfer and the third mission of universities. The article expands the predominant thinking about entrepreneurial universities and gives a broader structured definition. Eventually the article shows the need for STI policy to intervene and measures for developing entrepreneurial universities further.

• 한국산업정보학회논문지
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• 제22권4호
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• pp.29-43
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• 2017

Innovation Cosystems are Conceptualized as Organizational Networks of Economic Actors, Technologies and Social Contexts that Interact for Knowledge Production, use, and Adaptation. This Paper Proposed a Conceptual Framework to Describe Value Co-creation of Organizational Networks Engaged in Technology Innovation. We Adopted Theory-Based Approach by Integrating the Perspective of Service-Dominant (S-D) Logic Into the Evolutionary Model of the Triple Helix. The Framework Gives a Plausible Explanation on how Actors Collaborate to Create Value in Dynamic Contexts of an Innovation Ecosystem. The Innovation Ecosystem can be Considered as a Composite of Sub-Ecosystems, Including Knowledge, Sectoral, and Business Ecosystems. When these Sub-Ecosystems are Recursively Transformed by Coordination of Functional Mechanisms that Serve Value Co-creation in the Innovation Process, the Innovation Ecosystem will be Re-Organized and Evolve. The case of the Digital Living Network Alliance (DLNA) was Examined to Demonstrate the Fundamental Mechanisms for Value Co-creation that was Described in the Framework. The case Study Indicates Features of Value Co-creation when Implementing Innovation in Organizational Networks.

• 한국산업정보학회논문지
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• 제14권4호
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• pp.143-152
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• 2009

본 논문은 철강산업의 R&D 역량강화를 위해 IT 부문이 지원할 수 있는 정책을 모색하고 이에 대한 타당성을 검증한 사례연구이다. 기술추격형에서 기술선도형으로의 전환기에 놓여있는 국내 철강산업이 R&D 역량을 강화하기 위해서는 개별 철강사뿐만 아니라 대학, 연구소 등 외부와 개방형 R&D 연계체제를 적극 추진해야 한다. 이러한 상황 하에서 IT가 R&D 역량 강화를 효과적으로 지원하는 역할을 수행해야 한다. 본 연구에서는 이러한 목적을 갖는 IT 분야의 지원정책들을 개발하고 우선순위분석 등을 통해 제안된 정책들의 타당성을 검토하며, Triple Helix관점에서 정부, 기업, 학계의 역할을 논의한다.

• 한국콘텐츠학회논문지
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• 제22권9호
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• pp.194-204
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• 2022

이 연구는 웹사이트 크롤링을 통해 수집된 웹 데이터를 활용하여 지역 방송국의 사회적 자본과 지역 간 격차를 살펴보았다. 구체적으로 16개 지역 MBC 웹사이트와 연결된 URL을 수집하였다. 먼저, 웹 영향평가 조사를 통해 지역 방송국이 어느 기관과 연결되어 있는지 분석했다. 구체적인 연결 형태를 살펴보기 위해 n차 헬릭스 모델을 적용하여 URL 정보를 분류한 후 2원성 네트워크 분석을 진행하였다. n차 헬릭스 모델은 전통적 트리플 헬릭스 모델인 대학-기업-정부에 네트워크의 새로운 혁신 창출 주체를 추가한 분석 방법이다. 그 결과, 지역 방송국들은 지역 사회와의 교류에 있어 축제, 공연, 전시와 같은 프로그램을 가장 많이 활용하고 있었다. 지역별로는 대경권과 동남권에 속한 지역 MBC가 지역 사회와 가장 다양하게 연결된 것으로 나타났다. 이 연구를 통해 지역별 연결 구조를 살펴보고 지역 방송국 간의 차이를 인지할 수 있다는 점에서 의의가 있다. 후속 연구가 연결 형태에 초점을 맞춘 URL 종단분석을 실시한다면 더 구체적인 지역 간 격차를 파악할 수 있을 것이라 기대한다.