• 제목/요약/키워드: trial plan

검색결과 158건 처리시간 0.025초

한방 과립제의 폐경 후 삶의 질 개선 효과에 관한 연구 - 당귀작약산 및 계지복령환 과립제의 폐경후 삶의 질 개선에 대한 임상연구 (A Clinical Trial to Verity the Quality of Life Improvement Efficacy of Dangguijakyak-san and Gyejibongnyeong-hwan Granulation in Postmenopausal Women.)

  • 박제민;양정민;김동일
    • 대한한방부인과학회지
    • /
    • 제20권3호
    • /
    • pp.213-228
    • /
    • 2007
  • Purpose: This master‘s thesis to evaluate the grade of life after medication a Dangguijakyak-san(pasabu) and Gyejibongnyeong-hwan(cheongwal) with in postmenopausal women get lowering quality of life caused by vasomotor symptoms with hot flush. Methods: A subject who signing on the clinical trial written consent by self-will is registered this clinical trial after decided suitable by selection and exception standard, after take a medical experiment and checkup according to clinical trial plan. Registered subject should valuated by settled schedule after take the testing medicine 1,2 during thirty-day. In this period, a subject allocated at relatively better suited experimental group by oriental doctor after consideration of general efficacy and nature of a medicine at second visiting. Results: The result of comparison in the remedial value with sixteen patients who ended the experiment is like next list. 1. There's no regarded difference of comparison in general conditions between two patient groups. 2. There's no regarded difference during observation period before take medicine. 3. By period of measurement, there's something regarded differences most of patients of two parts after taking medicine. 4. There's no regarded difference at alteration phase of each standard according to kind of medicine. 5. There's no abnormal views reflected at allergy, Laboratory and Physical Examination during experiment. Conclusion: This experiment evidence a Dangguijakyak-san and Gyejibongnyeong-hwan can help for improvement generally life quality of postmenopausal women and certify safety of herbs.

  • PDF

산재장해인 재취업 지원방안: 시험고용(인턴) 제도를 중심으로 (Support strategy for industrial injured workers: focusing on trial work)

  • 조성재;김민;송창근
    • 한국산학기술학회논문지
    • /
    • 제20권10호
    • /
    • pp.259-269
    • /
    • 2019
  • 본 연구의 목적은 산재장해인의 재취업을 높이기 위해 시험고용 제도의 도입 필요성과 활성화 방안에 대해 알아보는 것이다. 이를 위해 근로복지공단에 등재된 산재발생 업체 1,058곳의 사업주를 대상으로 인터넷과 종이방식을 통해 설문조사를 실시하였다. 설문내용은 시험고용 제도 이용 경험여부, 만족도, 지원내용과 선호도에 대해 알아보았다. 2018년 9월부터 6주간 설문이 진행되었으며 수거된 설문 중 총 201부가 최종분석에 포함되었다. 빈도분석과 t-test를 이용하여 분석하였으며, 설문결과 시험고용 제도에 참여한 사업주들은 제도에 만족하는 것으로 나타났다. 보다 원활한 시험고용 제도 시행을 위해 제도신청 및 지원절차 간소화(t=2.73, p<.01), 지원금액 향상(t=3.41, p<.01), 정규직 전환 후 더 많은 지원제공(t=3.59, p<.001) 등이 필요한 것으로 나타났다. 이러한 요구는 제도에 참여하지 않은 사업주에 비해 참여한 경험이 있는 사업주에게서 그리고 비제조업보다 제조업에서 더 높게 나타났다. 원활한 제도 시행을 위해 사업주가 원하는 지원금액은 월평균 75만원, 지원기간은 평균 8개월로 나타났다. 응답자의 80%가 이러한 지원들을 바탕으로 시험고용 제도가 개발된다면 산재근로자를 고용하겠다고 응답하였다. 연구결과를 기반으로 시험고용 제도 도입과 적용가능성을 위한 정책적 제언과 연구의 한계점을 제시하였다.

Real Time Monitoring of Energy Efficiency Operation Indicator on Merchant Ships

  • Barro, Ronald Dela Cruz;Kim, Jun-Seong;Lee, Don-Chool
    • Journal of Advanced Marine Engineering and Technology
    • /
    • 제35권3호
    • /
    • pp.301-308
    • /
    • 2011
  • International Maritime Organization (IMO) proposed the Energy Efficiency Operation Indicator (EEOI) in 2005 and the Energy Efficiency Design Index (EEDI) in 2008 so as to address emission concern and regulation. Likewise, Ship Energy Efficiency Management Plan (SEEMP) and Greenhouse Gas (GHG) monitoring and management are also becoming an issue lately. This paper introduces the energy efficiency design index (operation indicator) monitoring system (EDiMS) software can continuously monitor $CO_2$, $NO_x$, $SO_x$, and PM values emitted from ship. The accurate inventory of ships GHG can be obtained from base of emission result during the engine shop test trial and the actual monitoring of shaft power and ship speed. In addition, the ability to store all exhaust emission and engine operation data can be applied as the useful tool of the inventory work of air pollution and ship energy management plan for the mitigation or reduction of ship emissions.

북한의 중재법의 주요 특징과 시사점 (Characteristics and Suggestions of Arbitration Act in North Korea)

  • 최석범
    • 한국중재학회지:중재연구
    • /
    • 제17권3호
    • /
    • pp.57-79
    • /
    • 2007
  • Laws regarding to Arbitration in North Korea are Arbitration Act, Foreign Economic Arbitration Act, Regulations on the Foreign Trade Arbitration Commission, Regulation for treatment of cases in Arbitration Commission, Rules of Hearing. North Korea has enacted the laws related to Arbitration including Arbitration Act enacted in 1995 and Foreign Economic Arbitration Act enacted in 1999. In the North Korea's planed economy system, as there will be many disputes among organizations, companies, other Institutions Arbitration Act resolves the disputes to compete the economic plan. North Korea's Arbitration Act is different from Normal Arbitration Acts in particular other socialist states in view of arbitration agreement and selection of arbitrator and functions as the tools controlling the members of North Korea and have the characteristics such as national arbitration system and mixture of criminal trial and governmental control and strict legal control system on violent acts in North Korea's plan and plan regulation. And North Korea's Arbitration Act deals with the civil disputes and limits the parties and subject matter of arbitration. The parties in dispute such as organizations, companies, other Institutions could apply for arbitration to Central Arbitration Body and Provincial (City under the direct control of Government) Arbitration Body and Sectional Arbitration Body. The purpose of this paper is to contribute to the enhancement of the understanding arbitration in North Korea by studying the clauses in the Arbitration Act.

  • PDF

방재마을 구축에 관한 연구 (Study on the Plan for Disaster Prevention Town Development)

  • 백민호;이지향
    • 한국방재학회 논문집
    • /
    • 제10권3호
    • /
    • pp.53-59
    • /
    • 2010
  • 전 세계는 자연환경의 변화로 지역적 폭우의 발생, 가뭄현상의 장기화, 대규모 지진발생이 증가하고 있는 실정이다. 우리나라의 경우도 방재개념이 적용되지 않은 지역에서 반복적으로 재해가 발생하여 대책이 시급하다는 지적을 받고 있다. 이에 소방방재청에서는 2009년부터 재해취약지역을 대상으로 방재시범마을의 조성을 추진하며 방재대책의 개선방안을 모색하고 있다. 본 연구에서는 방재마을구축과 관련하여 방재마을의 개념 및 사업 유형에 대해 정리하고, 관련제도, 국내 외 시범사업의 사례분석을 통해 방재마을 구축에 관한 발전전략을 제시하고 방재마을 조성에 대한 기본개념을 제시하여 방재마을 구축의 기초자료를 제시했다.

시험도로 건설과 계측시스템 구축 (A Review of Instrumentation System and Construction of Korea Highway Test Road)

  • 최준성;김도형;김성환
    • 한국지반공학회:학술대회논문집
    • /
    • 한국지반공학회 2000년도 가을 학술발표회 논문집
    • /
    • pp.603-606
    • /
    • 2000
  • The cost needed for the construction and management of highways in the whole nation is rapidly growing so the research that can decrease the cost is required. However, most of the highway specs have simply converted from those of other countries, including USA. Therefore, some of our design and construction specs were not the optimum ones based on our own situation, requiring a research under the actual traffic and environment of our nation. The use of test road develops many aspects of highway engineering. Those are evaluation of construction materials, a general overview of korea pavement design and serviceability under the actual traffic and environmental condition of the nation. It is also economical and efficient compared to the trial construction of each item in spreaded form. A test road, 7.7km long with two lanes, is being constructed on the Inner Central Expressway. In this test road, 2.7km is planned for asphalt pavement and 3.4km is planned for concrete pavement. Three test bridges and five earth retaining structures will be included in the test road. Based on the master plan, the major performance was progressing such as detailed research modules of each area, preliminary research for the future research, sensor surveys for the behavior analyses of pavements and structures with installation methods and data acquisition systems, the foundation research of Integrated Instrumentation System and the Management Plan for automated measurement. Some area(structure research division, geotechnical research division) was designed the instrumentation plan because some instrument sensors must be installed during the construction of the test road. And then the instrumentation plan of each area was enforcing because a large majority of the instrument sensors must be installed after the construction of the test road. The field surveys with material property tests and pilot instrumentation test with sensor tests was also performing in accordance with the construction in the field.

  • PDF

제초제의 효능과 약해 평가상의 당면과제 (Basic Features and Facts of Herbicide Evaluation for Efficacy and Phytotoxicity in Korea)

  • 권용웅
    • 한국작물학회지
    • /
    • 제23권3호
    • /
    • pp.19-30
    • /
    • 1978
  • Use of herbicides in Korean agriculture has increased rapidly in recent years accompanying with ever-increasing pressure of farm labor shortage. Herbicides occupied already the second place in the rank of pesticides consumption in 1977. The agricultural experiment stations have carried out over 50 trials of chemical weed control each year since 1968. These research works and registration trials contributed much to the present wide use of herbicides. The pesticide management act amended in 1977 requires reevaluation of pesticides for their efficacy every 5 year-term. However, the development of sound weed control program and recommendations has been hempered very much by the lack of qualified workers of weed control research in agricultural experiment stations and in the institute for pesticide registration trial. Critical review of the past research works on herbicide evaluation and the present status indicates strong need for 1) the characterization of the nature of local and national weed problem, 2) the improvement of ability of the staffs in charge of weed control research through appropriate training on the basics and experimental techniques, and 3) organization and activities of weed control research committee. Furthermore, the present article attempts to clarify commonly misled points in the establishment of herbicide evaluation plan, in the design and execution of field trials, and in the assessment of trial results of the past works from the viewpoint of the basic principles with some case studies for resolution of specific enigmas.

  • PDF

Mies van der Rohe 건축에서 나타난 재료의 표현특성에 관한 연구 (The Study on the Characteristics of Material appeared in the Architecture of Mies van der Rohe)

  • 이병욱;김용승;박용환
    • 한국실내디자인학회논문집
    • /
    • 제13권6호
    • /
    • pp.12-19
    • /
    • 2004
  • Mies van der Rohe is still known as the architect whose influence is the largest among modem architects. As his work is typical of modern architecture, the architecture of Mies shows an interest in materials and techniques, even though It established the new architectural world by glass and iron, and only transparency is emphasized with glass. So it is blame for the loss of peculiarity a result of thinking In the way of sachlich with expression and structure of material and hierarchical relation. Vincent Scully has insist on that an appearance of modem architecture be occur not by simply a technical request of a technician but by reflection of the times and times' spirit. In this means, the works of Mies is the trial to express the new times' spirit that the new times order and an understanding of material properties about glass with new material of modern. For that, this study tries to consider that Mies'work is the new trial through reflection of material to express about the bstraction beyond the limit of sachlich expression, on the point of expresslonal characteristics of material shown in plan of the Barcelona Pavilion and skyscraper and on the basis of the theory of Gottfried Semper and Karl Boetticher that architectural surface Is a medium which can define space and also express mass.

Establishing Rationale for the Clinical Development of Cell Therapy Products: Consensus between Risk and Benefit

  • Seunghoon Han;Hyeon Woo Yim;Hyunsuk Jeong;Suein Choi;Sungpil Han
    • International Journal of Stem Cells
    • /
    • 제16권1호
    • /
    • pp.16-26
    • /
    • 2023
  • Despite long-term research achievements, the development of cell therapy (CT) products remains challenging. This is because the risks experienced by the subject and therapeutic effects in the clinical trial stage are unclear due to the various uncertainties of CT when administered to humans. Nevertheless, as autologous cell products for systemic administration have recently been approved for marketing, CT product development is accelerating, particularly in the field of unmet medical needs. The human experience of CT remains insufficient compared with other classes of pharmaceuticals, while there are countless products for clinical development. Therefore, for many sponsors, understanding the rationale of human application of an investigational product based on the consensus and improving the ability to apply it appropriately for CT are necessary. Thus, defining the level of evidence for safety and efficacy fundamentally required for initiating the clinical development and preparing it using a reliable method for CT. Furthermore, the expertise should be strengthened in the design of the first-in-human trial, such as the starting dose and dose-escalation plan, based on a sufficiently acceptable rationale. Cultivating development professionals with these skills will increase the opportunity for more candidates to enter the clinical development phase.

대학수학능력시험에서 과학탐구 영역의 분석 (An Analysis of The Science Inquiry Items in Scholastic Ability Test for College)

  • 김상철;권재술
    • 한국과학교육학회지
    • /
    • 제14권2호
    • /
    • pp.214-224
    • /
    • 1994
  • The Ministry of Education established the plan to adopt a new college enterance examination system, so called Scholastic Ability Test for college, from 1994. The National Board of Educational Evaluation had carried out 7 experimental trials for the new examination system. Eventhough, the governmental officials advertised the purpose and characteristics of the new examination system, many students and parents did not understand the essential point very well. In this study the researcher tried to analyze the 7 trial examination items and the first Scholastic Ability Test for college carried out 1993. In this study, the researcher tried to find out all the items appeared in the 7 trials. In the analysis, all the individual items from the 1st trial to the 7th trial were used. The research results showed that the items were evenly distributed in all the four areas(Physics, Chemistry, Biology and Earth Science) of science content; however, they were heavily concentrated on data or information analysis categoris in the inquiry domain. In the domain of context, laboratory context was the major item context. The scores were also analyzed. The results showed that no significant difference between male and female students. However, science track students showed higher achievement scores than the non-science track student. The examination result showed high correlation with the tests routinely have carried out in schools. The over all analysis showed the new examination system showed very different characteristics to the conventional tests. Therefore, for the student to get successful result in the Scholastic Ability Test, they should change the way of study. They should try to understand scientific concepts rather than to memorize them. They should invest their time to carry out real experiments rather than to focus on the princples and laws of science. One of the most important thing would be for the student to apply what they learned to real life situations.

  • PDF