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Minimization of Treatment Time Using Partial-Arc Volumetric Modulated Arc Therapy with Bladder Filling Protocol for Prostate Cancer

  • Hojeong Lee;Dong Woon Kim;Ji Hyeon Joo;Yongkan Ki;Wontaek Kim;Dahl Park;Jiho Nam;Dong Hyeon Kim;Hosang Jeon
    • Progress in Medical Physics
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    • v.33 no.4
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    • pp.101-107
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    • 2022
  • Purpose: Radiotherapy after bladder filling protocol (BFP) is known to enhance treatment quality and reduce side effects in prostate cancer, a common male solid cancer globally. However, due to the need to hold back urine during treatment, patients frequently complain of discomfort, and treatment is frequently suspended when patients urinate during treatment and urine penetrates the treatment device, causing malfunction. Therefore, the effect of minimizing treatment time when partial-arc volumetric modulated arc therapy (VMAT) was used instead of full-arc was assessed in this study. Methods: A total of 70 plans were created in 10 patients using 7 different arc sizes, and the treatment time for each plan was calculated. Results: Reduced arc size by half resulted in a 54.4% decrease in mean treatment duration, with a proportional tendency observed. Furthermore, the effect of VMAT arc size reduction on target dose homogeneity was significantly limited, and the effect on surrounding organs at risk (OAR) was negligible. It should be noted, however, that when the arc size decreases by >40%, the dose increases in the area without OAR around the target. Conclusions: The results of this study demonstrated that partial-arc VMAT for enhancing treatment convenience and efficacy of prostate cancer patients undergoing BFP can achieve a considerable reduction in treatment time while preserving treatment quality, and it is expected to be useful for partial-arc VMAT plan design and implementation in practice.

Changes in Physicochemical and Antioxidant Properties of by Enzyme-Treated Super Sweet Corn Extracts (효소처리에 의한 초당옥수수 추출물의 이화학적 및 항산화 특성의 변화)

  • Byung-Ho In;Da-Bin Jang;Jae-Jun Lee;Won-Jong Lee;Ah-Reum Yoon;Sung-Kyu Kim;Kyung-Haeng Lee
    • The Korean Journal of Food And Nutrition
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    • v.36 no.6
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    • pp.526-534
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    • 2023
  • To improve usability of super sweet corn, extracts were prepared with hydrolytic enzyme and changes in physicochemical and antioxidant properties were analyzed. Soluble solids and reducing sugars contents were higher in all enzyme treatment groups than in the control. When enzyme treatment time increased, contents of soluble solids and reducing sugars were also increased. There was no significant difference in lightness between treatment groups, with redness showing the highest value in the control and yellowness showing the highest value in the invertase treatment group. Free sugar content in the control was the lowest. However free sugar content in the enzyme combination treatment group was increased by more than four times compared to that in the control. Contents of ascorbic acid, flavonoids and polyphenols were higher in the enzyme treatment group than in the control. In particular, the enzyme combination treatment group showed the highest content. DPPH and ABTS radical scavenging abilities were significantly higher in all enzyme treatment groups than in the control. Radical scavenging abilities of cellulase treatment group and enzyme combination treatment group showed high activity. The activity increased when enzyme treatment time increased. The combined enzyme treatment method for super sweet corn was suitable for food processing.

Physical Seed Treatment Techniques for Germination Enrichment and Seed Sterilization (발아증진 및 소독을 위한 물리적 방법을 이용한 종자처리 기술)

  • Si-Yong Kang
    • Journal of Radiation Industry
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    • v.17 no.2
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    • pp.199-207
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    • 2023
  • Since seeds can be directly used as food resources as well as for crop cultivation or preservation of genetic resources, it is essential to develop high-quality seed processing technology to increase agricultural productivity. Seed treatment means processing technologies of seeds through physical or chemical treatment processes from after harvesting seeds to before sowing of seeds to improve germination and growth rate, durability, and immunity, etc. Since chemical seed treatment technology using pesticides or plant growth regulators has problems of environmental pollution and human toxicity, it is desired to develop an alternative technology. As a physical seed treatment method, various technologies such as ionizing radiation, plasma, microwave, and magnetic field are being developed, and some of them are being used practically. In this paper, I will summarize the mechanism of seed priming and disinfection, and the advantages and disadvantages of application, focusing on these physical seed treatment methods. Low dose or moderate intensity ionizing radiation, microwave, low-temperature plasma, and magnetic field treatments often promoted seed germination and seedling growth. However, effective removal of direct seed pathogens at these treatment intensities appears to be difficult. And it has been shown that relatively high-dose electron beam treatment using low-energy electron beams kills microorganisms on the seed surface and hull layer while not damaging the inner tissue of the seed, and is also effectively used for seed treatment on a commercial scale. In order to put the physical seed treatment technology to practical use in Korea, it is necessary to develop an economical scale treatment device along with the development of individual treatment technology to each crop.

A Case Report for One Case of Thyrotoxic Periodic Paralysis Patient

  • Lee Kyung-Hwan;Kim Yong-Seong
    • The Journal of Korean Medicine
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    • v.25 no.4
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    • pp.226-234
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    • 2004
  • Objective : The thyrotoxic periodic paralysis mainly appears in case of hyperthyroidism and the amyotonia is the characteristic main symptom. Through the deteriorated case and treatment by oriental medicine, the purpose of this research is to study the change of symptoms and the treatment effect for one case of a thyrotoxic periodic paralysis patient, Methods and Results : The treatment was carried out with oriental medicine as a main treatment and by the oriental medicinally deteriorated case, acupuncture treatment, moxibustion treatment and herbal medicine treatment were used as the main treatment methods. Also based on the symptoms which could appear with hyperthyroidism, the changes of symptoms were evaluated once a day with 4 levels of subjective scales that the patient was feeling, by dividing with 4 aspects of totalis symptoms, cardiovascular symptoms, musculoskeletal symptoms and other symptoms. In addition, it was shown that through the continuous hematologic test, the subjective and objective symptoms were mostly decreased during the treatment periods by comparing with the objective thyroid hormone (T3, T4, TSH) levels and the electrolyte levels. Conclusion : With this result, it was considered that oriental medicinal treatment was very effective for the thyrotoxic periodic paralysis through the oriental medicinally deteriorated case.

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Review of Clinical Researches about Korean Medicine Treatment on Language Disorder of Cerebral Palsy (뇌성마비 언어장애에 대한 한의 치료 연구 동향)

  • Kim, Lakhyung;Yu, Gyung
    • The Journal of Pediatrics of Korean Medicine
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    • v.26 no.4
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    • pp.32-37
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    • 2012
  • Objectives: The purpose of this study was to obtain some understanding about Korean medicine treatment on language disorder in cerebral palsy for future practice and the research, from the clinical studies. Methods: The literature was searched using the database-China Academic Journals (CAJ). Clinical studies of Korean medicine treatment for language disorder in cerebral palsy, including Randomized controlled trial (RCT), case control study, case series, case report were analyzed. Results: Fifteen Clinical studies met our inclusion criteria; One case study and six case series, one non-randomized controlled trial and seven RCTs. Acupuncture treatment, especially Head acupuncture, was the major treatment for language disorder of cerebral palsy in clinical studies, as it was used in fourteen studies. Acupoint massage, tuina, and acupoint injection were employed as treatment methods in the studies. Acupuncture treatment was used for language disorder of cerebral palsy combined with language therapy and other rehabilitation treatment in many studies. The effectiveness in the treatment groups, regardless of treatment methods, was higher than that of control group in all RCT studies. Conclusions: The results of this study could be used in the practice and the future study about language disorder of cerebral palsy.

REACTION TIME, SEMEN OUTPUT AND SEMEN QUALITY OF BUFFALO BULLS AFTER PRE-COLLECTION INJECTION OF PROSTAGLANDIN F2 ALPHA (PGF2 ALPHA)

  • Capitan, S.S.;Antiporda, G.S.;Momongan, V.G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.3 no.4
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    • pp.343-346
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    • 1990
  • A study was conducted to determine the effect of prostaglandin $F_2$ alpha ($PGF_2$ alpha) on the reaction time and seminal characteristics of buffalo bulls. Semen was collected from three Murrah bulls in three periods: pre-treatment, treatment and post-treatment. During the treatment period each bull was administered 2 ml $PGF_2$ alpha (Synchrocept, Fenprostalene) im, 1 hour prior to semen collection. In the post-treatment, semen was collected 7 days after the last injection of $PGF_2$. Semen samples were evaluated immediately after collection. Pre-collection injection of $PGF_2$ alpha has no significant effect on reaction time, semen volume, percentage motility, sperm concentration and total number of sperms per ejaculate. Fluctuations in semen color and consistency were observed. There is a significant (p<0.05) increase in the mean percentage of normal spermatozoa during the treatment and post treatment periods. Likewise, administration of PG results into a significant (p<0.05) rise on the average percentage of live sperms but this effect was not manifested in the post-treatment period. Improvement in mass activity was observed during the treatment and post-treatment periods.

Curing of meat batter by indirect treatment of atmospheric pressure cold plasma

  • Jo, Kyung;Lee, Juri;Lim, Yubong;Hwang, Jaejun;Jung, Samooel
    • Korean Journal of Agricultural Science
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    • v.45 no.1
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    • pp.94-104
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    • 2018
  • Nitrite is an essential additive for cured meat product. Plasma is ionized gas and reactive nitrogen species in plasma can be infused into meat batter and subsequently generate nitrites by reaction with water molecules after plasma treatment. However, the increase of nitrite in meat batter is limited with direct treatment of atmospheric pressure cold plasma because of the increase of meat batter temperature. Therefore, this study investigated the influence of indirect treatment of atmospheric pressure cold plasma on the physicochemical properties of meat batter. Meat batter was indirectly treated with plasma at 1.5 kW for 60 min. The pH of meat batter decreased while the temperature increased with plasma treatment time. The total aerobic bacterial count of meat batter was not affected by plasma treatment. The nitrite content of meat batter was increased to 377.68 mg/kg after 60 min of plasma treatment. The residual nitrite content of cooked meat batter also increased with plasma treatment time. The CIE $a^*$-value of cooked meat batter increased. As plasma treatment time increased, lipid oxidation tended to increase and protein oxidation significantly increased. According to these results, the indirect treatment of atmospheric pressure cold plasma can be used as a new curing method for replacing synthetic nitrite salts.

Interdisciplinary treatment of Class III malocclusion using mini-implant: problem-oriented orthodontic treatment (Mini-implant를 이용한 III급 부정교합 환자의 협진 치료: 문제중심의 교정치료)

  • Im, Dong-Hyuk;Kim, Young-Shin;Cho, Min-Ah;Kim, Ki-Sung;Yang, Sung-Eun
    • The korean journal of orthodontics
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    • v.37 no.4
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    • pp.305-314
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    • 2007
  • Interdisciplinary treatment of Class III malocclusion with congenital missing of unilateral maxillary canine and anterior crossbite is discussed focusing on a problem-oriented treatment planning, treatment progress, and treatment result. Maxillary mini-implant provided anchorage for distalization of the maxillary right porsterior dentition. Mandibular mini-implants were used to distalize the whole mandibular dentition. Total treatment time was 17 months to achieve a successful treatment goal. Stable occlusion was maintained after 12 months of retention.

The study on external treatment of oriental medical care on acne (여드름의 한의학적 치료에 관한 고찰;국내 논문, 외용약을 중심으로)

  • Kim, Min-Ae;Kim, Mi-Bo;Shin, Sang-Ho;Byun, Seok-Mi;Ko, Woo-Shin;Lee, Ho-Sub;Park, Sun-Gyoo;Yoon, Hwa-Jung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.21 no.2
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    • pp.102-111
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    • 2008
  • Background : The purpose of this study is to make the oriental medicine treatment useful and develop the way of acne cure. Object&Metbod : This study is based on analysis of Recent paper about Oriental medicine of acne, mainly for the external treatment. Results: We analyzed recent treatis about acne cure with external treatment in clinical and analytic study. For the first, there are various clinical approaches with: single use of external treatment, external treatment and herb medicine methods and acidic ionized water. The others are about practical applications on the external treatment, and traditional chinese medical approaches. Conclusion: To develop the better medical care on acne, development and verifications of various treatment methods are necessary on the basis of the merits of oriental treatment.

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A Clinical case study for the diagnosis and assessment of abdominal cold hypersensitivity treatment by DITI (적외선 체열검사(DITI)로 복부냉증의 진단과 치료 경과를 평가한 단일 임상례)

  • Kim, Eun-Gyung;Hwang, Deok-Sang;Lee, Chang-Hoon;Lee, Kyung-Sub
    • Journal of Oriental Medical Thermology
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    • v.7 no.1
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    • pp.55-65
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    • 2009
  • Purpose: This study was performed to evaluate DITI (Digital Infrared Thermographic Imaging)'s potential for diagnosis and indicator of abdominal cold hypersensitivity treatment from the clinical case study. Methods: The patient was a 35-year-old woman who was suffered by general coldness, sweating and general pain. The patient was treated by Herb medicine, Acupuncture treatment, Moxa treatment and Physical Treatment. The progress of symptoms was evaluated by checking the change of VAS, and inspecting the DITI. We studied the statistical significance from the difference of DITI results before and after treatment by paired T-test using SPSS windows (version 12.0). Results: The general coldness, sweating and general pain of this patient have declined, especially the abdominal coldness improvement showing. As a results, the temperature of four abdominal sites(GV4,6,12,17) after treatment were statistically higher than those before treatment. With comparison of Indang, DITI difference of abdominal sites before and after treatment were statistically significant from paired T-tests. Conclusion: The results suggest that DITI can be used for the diagnosis and assessment of abdominal cold hypersensitivity treatment.

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