• Title/Summary/Keyword: treatment strategy

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Respiratory Reviews in Asthma 2013

  • Kim, Tae-Hyung
    • Tuberculosis and Respiratory Diseases
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    • v.76 no.3
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    • pp.105-113
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    • 2014
  • From January 2012 up until March 2013, many articles with huge clinical importance in asthma were published based on large numbered clinical trials or meta-analysis. The main subjects of these studies were the new therapeutic plan based on the asthma phenotype or efficacy along with the safety issues regarding the current treatment guidelines. For efficacy and safety issues, inhaled corticosteroid tapering strategy or continued long-acting beta agonists use was the major concern. As new therapeutic trials, monoclonal antibodies or macrolide antibiotics based on inflammatory phenotypes have been under investigation, with promising preliminary results. There were other issues on the disease susceptibility or genetic background of asthma, particularly for the "severe asthma" phenotype. In the era of genome and pharmacogenetics, there have been extensive studies to identify susceptible candidate genes based on the results of genome wide association studies (GWAS). However, for severe asthma, which is where most of the mortality or medical costs develop, it is very unclear. Moreover, there have been some efforts to find important genetic information in order to predict the possible disease progression, but with few significant results up until now. In conclusion, there are new on-going aspects in the phenotypic classification of asthma and therapeutic strategy according to the phenotypic variations. With more pharmacogenomic information and clear identification of the "severe asthma" group even before disease progression from GWAS data, more adequate and individualized therapeutic strategy could be realized in the future.

An Exploratory Study on the Human Resource Management Strategy of Non-Standard Workers in the Korean Companies (한국기업에서 비정규직의 인적자원관리전략에 관한 탐색적 연구)

  • Park, Min-Saeng
    • Management & Information Systems Review
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    • v.24
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    • pp.73-75
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    • 2008
  • The purpose of this study is to propose the human resource management strategies of non-standard workers that can contribute to accomplishing both corporate social responsibility and business purpose in efficient and effective ways. For the purpose, this researcher investigated circumstances under which Korean companies are using non-standard workers and systems related to those workers. In Korea, the Non-Standard Workers Protection Act was enacted and revised, and became effective on July 1, 2007. The main provisions of the act are as follows. First, the systems of discriminatory treatment prohibition was legally stipulated, Second, restrictions on overwork for fixed-term and part-time employees and the written statement of working conditions were compelled. Third, only 26 kinds of jobs were permitted for worker dispatch in accordance with positive list system. To achieve their business purpose, companies often use standard workers, but sometimes non-standard workers unavoidably in accordance with their business strategy. This study propose main human resource management strategies of non-standard workers such as determining the scope of jobs, strengthening legal and systematic human resource management, improving human relations, extending the grievance procedure and converting non-standard workers into standard ones.

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The Impact of Using Some Participatory E-learning Strategies in Developing Skills of Designing and Producing Electronic Courses for A sample of Umm Al-Qura University Students and their Innovative Thinking

  • Emad Mohammed Samra
    • International Journal of Computer Science & Network Security
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    • v.23 no.3
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    • pp.17-30
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    • 2023
  • The current research aims to reveal the impact of using some participatory e-learning strategies (participatory product - classroom web simulation) in developing cognitive achievement, electronic course design skills, and - skills list - Torrance test of innovative thinking). The tools of innovative thinking among a sample of Information Science students. To achieve the objectives of current research, the researcher designed an educational website to train students to produce electronic courses via the web, according to the two participatory e-learning strategies. The researcher used a set of tools represented in (achievement test research and experimental treatment were applied to a sample of the Faculty of Computer students at Umm Al-Qura University. The results found that both participatory product strategy and web simulation have an imact on developing learning aspects discussed in the research. As for which of the two strategies had a greater impact than the other, it turned out that the web simulation strategy had a greater impact than the participatory product strategy in developing these aspects.

Mediating Effects of Role Perception of Life-sustaining Treatment in the Relationship between Knowledge of Life-sustaining Treatment Plans and Attitudes toward Withdrawal of Life-sustaining Treatment among Nursing College Students

  • Park, Youngmi;Nam, Keumhee;Bae, Joohee
    • Journal of Hospice and Palliative Care
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    • v.24 no.1
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    • pp.36-45
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    • 2021
  • Purpose: This study examined the relationship between Knowledge of Life-sustaining Treatment Plans and Attitudes toward Withdrawal of Life-sustaining Treatment among nursing college students, and attempted to identify the mediating effect of Role Perception on Life-sustaining Treatment in that relationship. It is hoped that the findings will ultimately contribute to the development of active nursing strategies. Methods: The participants were 142 nursing college students in the third and fourth years of study who had experienced clinical practice at two universities in cities Y and C. Data were collected from November 1 to 30, 2019. For data analysis, SPSS for Windows version 22.0 was used to calculate descriptive statistics, the t-test, Pearson's correlation coefficients, and multiple regression. To analyze the mediating effect, the Baron and Kenny bootstrapping method was used. Results: Attitudes toward Withdrawal of Life-sustaining Treatment of nursing college students had a significant positive correlation with Knowledge of Life-sustaining Treatment Plans (r=0.34, P<0.001) and Role Perception on Life-sustaining Treatment (r=0.44, P<0.001). Role Perception on Life-sustaining Treatment partially mediated the relationship between Knowledge of Life-sustaining Treatment Plans and Attitudes toward Withdrawal of Life-sustaining Treatment (95% CI, 0.446~1.055). Conclusion: Based on the results of this study, improving nursing college students' Role Perception on Life-sustaining Treatment could be used as a coping strategy to establish positive Attitudes toward Withdrawal of Life-sustaining Treatment.

Development of the Water Treatment System with High Performance Electromagnetic Field (고성능 전자장을 갖는 수처리 시스템의 개발)

  • Lee, Yong-Geun
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.54 no.3
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    • pp.155-159
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    • 2005
  • This paper presents the water treatment system with high performance electromagnetic field for a good quality of water. The electromagnetic field water treater consists of a solion, a solion body, and a high voltage converter. The high voltage converter is controlled by PWM current controller. The high voltage converter of 13W is designed for an isolation operation amp, an isolation current detector, and an over current protector. Using the high voltage PWM converter, the system with the proposed electromagnetic field water treater can be controlled easily. Simulation and experimental results show the effectiveness of the system strategy proposed for the scale rejection.

Somatoform Disorders of Children and Adolescents (소아 및 청소년의 신체형장애)

  • Kim, Seung-Tai P.
    • Korean Journal of Psychosomatic Medicine
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    • v.4 no.2
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    • pp.277-285
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    • 1996
  • Somatoform disorders do occur among children and adolescents. Among the seven disorders under the grouping of somatoform disorders of DSM-IV, three disorders, namely somatization disorder, pain disorder and conversion disorder are seen relatively more often than one can expect in childhood and adolescence. Pain disorders are more prevalent among children before adolescence, whereas conversion disorder and somatoform disorder are seen more often during adolescence and early adulthood. Diagnoses of somatofram disorders should not be made by the process of exclusion, but based on positive findings that positive evidence that normal functioning is possible and that a positive history of psychosocial stress and or intrapsychic conflict exists. Treatment strategy should be mindful of including collaboration with primary care health professionals and family therapy staff in addition to all the basic treatment modalities essential for the treatment of children and adolescents.

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Strategy for efficient operation on the backwash waste treatment in membrane filtration water treatment plant (막여과 정수장 배출수처리시설의 효율적인 운영방안)

  • Jung, Wonchae;Yu, Youngbeom;Lee, Sunju;Moon, Yongtaik
    • Journal of Korean Society of Water and Wastewater
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    • v.28 no.4
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    • pp.479-489
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    • 2014
  • Membrane backwashing waste shows seasonally different characteristics and it has bad settleability differently from general backwashing waste in water treatment plant. When chemicals was injected to membrane backwashing waste, the settleability was better than chemicals was not injected. However, when settled lower sludge was not discharged, flowing sludge continuously was concentrated over a certain surface and floatation penomena occurred according to flowing velocity. When the lower sludge was discharged continuously in the thickener to prevent floatation penomena of turbidity materials, the depth of sludge surface was the least and the settleability increased.

Community-based Hypertension Control Program in Hwachon : Problems and Possibilities (보건소조직을 통한 고혈압관리사업)

  • 이인숙;배상숙
    • Health Policy and Management
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    • v.3 no.2
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    • pp.25-56
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    • 1993
  • Hypertension has already become a serious health problem in many countries. Treatment is effective, however, and the detection and long-term management of those at risk pose sustained challenges. Community programs can be an important strategy for primary prevention of hypertention and for monitoring the progress and promoting compliance of hypertensive patients. Hwachon Health Demonstrain Project has designed community hypertention control program, especially emphasizing role of public health sector, and operate that model from 1990 at Hwachon county, Kwangwon province. This paper appraise the effectiveness of curent activities. Many paper appraise the effectiveness of curent activities. Many hypertensive persons who have not recognized his disease were identified and began hypertension treatment. However about two thirds of patients have not complied continuously with medical advice. Consequently, the project team redirects its efforts. Less emphasis is being placed screening and identification of patients, while more emphasis is being placed on increasing compliance with treatment recommendations. Some approches to improve hypertension control program are also discussed in the context of the field experience and literature on this suvjest.

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Contradictory Relationships between Cancer and Normal Cells and Implications for Anti-cancer Therapy

  • Gou, Xing-Chun;Kong, Derek;Tang, Xu
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5143-5147
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    • 2015
  • Cancer treatment remains a serious problem worldwide. Analysis of the relationship between cancer cells and normal cells reveals that these two share characteristics in contradiction, thus could be analyzed by using contradictory principles. Under the theory of contradictory principles, induction of a dormant state or reversal of cancer cells is an important treatment strategy beyond traditional cytotoxic therapy. Normal cells are also the targets and under the influence of anti-cancer treatments and should be considered during therapy. Findings based on crosstalk between these two cell types may offer opportunities for the development of new biomarkers and therapies.

Nedaplatin Salvage Chemotherapy for Cervical Cancer

  • Li, Wu-Ju;Jiang, Jia-ying;Wang, Xian-Lian
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3159-3162
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    • 2015
  • Purpose: This systematic analysis was conducted to evaluate the efficacy and safety of nedaplatin based salvage chemotherapy for treatment of patients with advanced cervical cancer. Methods: Clinical studies evaluating the efficacy and safety of nedaplatin based regimens on response and safety for patients with cervical cancer were identified using a predefined search strategy. Pooled response rates (RRs) were calculated. Results: For nedaplatin based regimens, 5 clinical studies including 264 patients with advanced cervical cancer were considered eligible for inclusion. The analysis showed that, in all patients, pooled RR was 74.6% (197/264). Major adverse effects were leukopenia, thrombocytopenia and nausea/vomiting. No treatment related death occurred with nedaplatin based treatment. Conclusion: This systematic analysis suggests that nedaplatin based regimens are associated with good activity with acceptable tolerability in treating patients with advanced cervical cancer.