• 제목/요약/키워드: treatment failure

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신생아 급성 신부전의 치료 (Treatment of Acute Renal Failure in Neonate)

  • 이진아
    • Neonatal Medicine
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    • 제17권2호
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    • pp.168-180
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    • 2010
  • Acute renal failure (ARF) is common in the neonatal period, however, there are no uniform treatment strategies of ARF. The main treatment strategies are conservative management including medical treatment and the renal replacement therapy. Because ARF in the newborn is commonly acquired by hypoxic ischemic injury and toxic insults, removal of all the offending causes is important. Aminoglycoside, indomethacin, and amphotericin-B are the most common nephrotoxic drugs of ARF. To relieve the possible prerenal ARF, initial fluid challenge can be followed by diuretics. If there is no response, fluid restriction and correction of electrolyte imbalance should begin. Adequate nutritional support and drug dosing according to the pharmacokinetics of such drugs will be difficult problems. Renal replacement therapies may be provided by peritoneal dialysis, intermittent hemodialysis, or hemofiltration. New promising agents, bioartificial kidney, and stem cell will enable us to extend our therapeutic repertoire.

체외수정에서 반복 착상 실패(RIF) 환자 침치료 최근 연구 동향 (Recent Research Trends of Acupuncture Treatment for Recurrent Implantation Failure (RIF) Patients in In Vitro Fertilization)

  • 조세연;김승규;황덕상;이진무;장준복;이창훈
    • 대한한방부인과학회지
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    • 제37권2호
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    • pp.120-134
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    • 2024
  • Objectives: This research aimed at investigating the trends of acupuncture treatment for Recurrent Implantation Failure (RIF) patients in IVF. Methods: Studies were searched from PubMed, Cochrane Library, EMBASE, CNKI up to April 2024. Terms as 'Implantation failure', 'Recurrent implantation failure', 'Repeated implantation failure', 'RIF' and 'Acupuncture', 'Electroacupuncture', 'Needling' were used. Results: Of 136 screened, 10 studies are selected and analyzed. Studies were conducted using manual acupuncture and electroacupuncture. The results showed that acupuncture (electroacupuncture) treatment for RIF patients is effective in improving clinical pregnancy rate, endometrial blood flow, uterus morphology, endometrium thickness. The most frequently used acupoints were 三陰交 (SP6) and 子宮 (EX-CA1). Conclusions: Included studies showed that acupuncture (electroacupuncture) might have effect on RIF. Further research and meta-analysis should be conducted to verify its therapeutic mechanisms and safety.

조기난소부전 진단 후 한방치료를 통해 자연임신에 성공한 환자 1례의 임상증례보고 (A Clinical Study on One Case of a Spontaneous Pregnancy with Premature Ovarian Failure)

  • 백종순
    • 대한한방부인과학회지
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    • 제31권2호
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    • pp.95-102
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    • 2018
  • Objectives: The purpose of this paper is to report the effects of herbal medicine on spontaneous pregnancy with premature ovarian failure. Methods: The 28-year-old patient who was diagnosed premature ovarian failure was treated with herbal medicine (Hyangbujapalmul-tang-gagam), acupuncture and moxibustion. Results: After the treatment, the symptoms of premature ovarian failure such as hot flushes, sweats were improved. The patient recovered menstruation and achieved spontaneous pregnancy. Conclusions: This case shows that Korean medical treatment including herbal medicine has effect on treating infertile female with premature ovarian failure.

Recovery of complete left bundle branch block in dilated cardiomyopathy after optimal heart failure treatment: a case report

  • Geum Ko;Jae-Geun Lee
    • Journal of Medicine and Life Science
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    • 제21권3호
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    • pp.112-116
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    • 2024
  • Complete left bundle branch block (CLBBB) is a significant cardiac conduction abnormality often associated with dilated cardiomyopathy (DCM). This case report highlights the improvement in CLBBB and symptom relief through reverse cardiac remodeling in a patient diagnosed with DCM following an optimized heart failure treatment regimen consisting of an angiotensin-converting enzyme inhibitor, beta-blocker, and mineralocorticoid receptor antagonist. This case highlights the potential of electrical remodeling and conduction system improvement in patients with DCM receiving optimized medical therapy.

Efficacy of conservative treatment of perianal abscesses in children and predictors for therapeutic failure

  • Boenicke, Lars;Doerner, Johannes;Wirth, Stefan;Zirngibl, Hubert;Langenbach, Mike Ralf
    • Clinical and Experimental Pediatrics
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    • 제63권7호
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    • pp.272-277
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    • 2020
  • Background: The optimal management of perianal abscess in children is controversial. Purpose: To evaluate the efficiency of conservative treatment of perianal abscess in children and identify parameters that predict therapy failure. Methods: All cases of children younger than 14 years of age with perianal abscesses between 2001-2016 were evaluated. Results: Of the 113 enrolled patients, 64 underwent subsequent surgery for advanced disease (primary surgery group). Conservative treatment was initiated in 49 patients (primary conservative group) but was stopped because of inefficiency in 25 patients, who were referred for surgery after a median 7.03 days (range, 2 to 16 days). The other 24 patients (48%) initially achieved complete remission after conservative treatment, but 10 were readmitted after a median 34 months (range, 3 to 145 months) with recurrent disease. There were no significant differences in permanent success after conservative treatment between infants (10 of 29, 34%) and older children (4 of 20 [20%], P=0.122). Overall, conservative treatment alone was effective in only 14 of 113 patients. Recurrence after surgery occurred in 16 patients (25%) in the primary surgery group and 11 patients (22%) in the primary conservative group (P=0.75). Univariate analysis of predictors for conservative treatment failure revealed inflammatory values (C-reactive protein and white blood count, P=0.017) and abscess size (P=0.001) as significant parameters, whereas multivariate analysis demonstrated that only abscess size (odds ratio, 3.37; P=0.023) was significant. Conclusion: Conservative treatment of perianal abscess is permanently efficient in only a minority of children but is not associated with a higher recurrence rate after subsequent surgery. Abscess size is a predictor for therapy failure.

급성 Paraquat 중독 후 발생한 급성 신부전 환자 2예 (Two Cases of Acute Renal Failure Caused by Acute Paraquat Poisoning)

  • 장통영;정용준;김관식;서관수;한명아;신선호;김동웅
    • 대한한의학회지
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    • 제21권4호
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    • pp.276-285
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    • 2000
  • Paraquat is a very potent herbicide which causes fatal toxicity when ingested, and there is no specific antidote against it. Human ingestion induces acute renal failure, hepatic dysfunction and progressive respiratory failure with high mortality rate. Clinical investigation and medical treatment were done on two cases of acute renal failure caused by paraquat poisoning admitted to the Department of Internal Medicine, Wonkwang University Oriental Chonju Medical Hospital. We report two cases of patients who survived after acute paraquat intoxication, by means of oriental medicine such as Gamdutang, a typical antidote of toxins, chinese ink as an absorbent and burned powder of Rhei Radix et Rhizoma for laxative and so on, western medicine such as gastric lavage, diuretics and fluid therapy. We suggest more experiments and studies related to such treatment for paraquat poisoning be conducted.

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Cardiac Resynchronization Therapy Defibrillator Treatment in a Child with Heart Failure and Ventricular Arrhythmia

  • Kim, Hak Ju;Cho, Sungkyu;Kim, Woong-Han
    • Journal of Chest Surgery
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    • 제49권4호
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    • pp.292-294
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    • 2016
  • Cardiac resynchronization therapy (CRT) is a new treatment for refractory heart failure. However, most patients with heart failure treated with CRT are adults, middle-aged or older with idiopathic or ischemic dilated cardiomyopathy. We treated a 12-year-old boy, who was transferred after cardiac arrest, with dilated cardiomyopathy, left bundle-branch block, and ventricular tachycardia. We performed cardiac resynchronization therapy with a defibrillator (CRT-D). After CRT-D, left ventricular ejection fraction improved from 22% to 4 4% assessed by echocardiogram 1 year postoperatively. On electrocardiogram, QRS duration was shortened from 206 to 144 ms. The patient's clinical symptoms also improved. For pediatric patients with refractory heart failure and ventricular arrhythmia, CRT-D could be indicated as an effective therapeutic option.

침탄처리된 기어의 미세 조직학적 손상 원인분석 (Failure Analysis of Carburized Gears by Microstructural Observation)

  • 전해동;장성호;김경욱;국연호
    • 열처리공학회지
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    • 제27권4호
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    • pp.191-201
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    • 2014
  • The gear was made of SNC815 case-carburized, quench hardened and tempered steel. The gears were failed far earlier than the expected service life used in the industrial site. Causes of the failed gear were analyzed by microstructure observation. By the SEM and micro structure examinations, the damaged surfaces had been weared and failed by fatigue. Through microscope observation on the damaged surface, it was found that the cause of failure was determined by external overloading and the initial stage of the damage was closely related to complex contact fatigue failure. The overload and contact fatigue contributed to the early failure cause.

한방치료를 통한 월경주기 회복 후 배란유도를 통해 임신과 출산에 성공한 조기난소부전 환자 치험 1례 (A Clinical Study on 1 Case of Infertility Patient with Premature Ovarian Failure)

  • 장새별;정은혜;최경희;유동열
    • 대한한방부인과학회지
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    • 제27권3호
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    • pp.135-142
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    • 2014
  • Objectives: The purpose of this study is to report the effects of herbal medicine on infertility caused by premature ovarian failure. Methods: The patient in this case was 38-year-old female. The patient was diagnosed premature ovarian failure by serum hormone assay. The chief complain is amenorrhea and infertility. She was treated by traditional treatment, such as herbal medicine (Buickjihwang-hwan), acupuncture and moxibustion. Results: After the treatment, the patient recovered the menstrual cycle and became pregnancy and delivery. Conclusions: This case shows that traditional Korean treatment might be effective in infertility caused by premature ovarian failure.

조기난소부전의 한의학적 치료에 대한 국내 연구 동향 고찰 (A Review of the Domestic Study Trends on Premature Ovarian Failure Treated with Korean Medicine)

  • 김민경;김순아;김수진;정우진;허효승;김혜경
    • 대한한방부인과학회지
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    • 제33권3호
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    • pp.20-39
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    • 2020
  • Objectives: This study was performed to examine the domestic study trends on premature ovarian failure (POF) treated with Korean medicine. Methods: We investigated the studies on Korean medicine treatment for premature ovarian failure via searching 4 online databases. Results: 13 clinical studies were selected. All studies were the noncomparative studies, and mainly case reports. Studies were publicated from 2001 to 2019 and the number of studies with 1 subject was the greatest (76.9%). In accompanying symptoms, there was a study which did not report entire cases. In the 11 case reports (13 subjects), the most accompanying symptoms was hot flush (69.2%). In treatment of premature ovarian failure, the most used treatment was herbal medicine, which was used in all studies. Acupuncture treatment was used in 6 studies (46.2%) and moxibustion treatment was used in 8 studies (61.5%). The most common acupuncture point was 內關 (SP6) in acupuncture treatment, and was 關元 (CV4) in moxibustion treatment. The duration of treatment was between 1 month and 20 months, the average 7.76 months. Used outcome measurements were hormone test (84.6%), menstruation (76.9%), Visual analog sclale (VAS) (15.4%), ultrasonography (15.4%), Numeral rating scale (NRS), Body basal temperature (BBT) and Kupperman index (7.7%). In total 70 subjects, 13 subjects (18.6%) became pregnancy and 25 subjects (35.7%) had no effect. Follow up was reported in 6 studies, and the average duration of follow up was 141.63 days. Conclusions: Further clinical trials are needed to establish the evidence for Korean Medicine treatment for premature ovarian failure.