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Effectiveness of Korea Red Ginseng in Erectile Dysfunction-Multi-National Approach (발기부전 환자에서의 홍삼의 효능에 관한 연구 -동남아시아의 다국적 연구)

  • Choi Hyung Ki;Choi Young Deuk;Adaikan P. Ganesan;Jiang Yu
    • Journal of Ginseng Research
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    • v.23 no.4
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    • pp.247-256
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    • 1999
  • Ginseng has been used in maintaining physical vitality throughout the far-eastern countries and recently its metabolism and actions on neurologic, cardiovascular, and endocrinologic systems are studied. Korean red ginseng (KRG) has been used in various ailments, and to prove its efficacy for erectile dysfunction an international study on Asians other than Korean was performed. Patients with borderline organic and psychogenic erectile dysfunction were included. KRG were given daily, and placebo were given as controls. Treatment lasted a total of 3 months. Surveys including libido, erection, ejaculation, sexual activity, and sexual satisfaction were given. Serum testosterone and erectile function study were taken. Among the 64 patients, 37 patients were followed with KRG. Five had diabetes, 5 hypertension, 5 hypercholesterolemia, 6 low testosterone, 6 psychogenic, and 11 idiopathic. The improvement after KRG administration was $70.2\%$ on objective questionnaire and $75.7\%$ on subjective analysis. When KRG were given, all parameters surveyed have shown improvements compared to the placebo. The effects of KRG in Chinese and Singapores were similar to the Koreans. Serum testosterone levels were nonnalized in 6 patients with KRG, who's serum testosterone levels were reduced from pre-study. Two patient reported constipation, and 2 gastric upsets in the KRG group. In conclusion, KRG has beneficiary action on male erectile capabilities with little side effects. KRG is effective in Koreans and also Asians. The exact action mechanism and the active ingredients in KRG need to be studied.

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Clincal Efficacy of Korean Red Ginseng for Erectile Dysfunction -Multi-national Approach

  • Choi, Hyung-Ki;Choi, Young-Deuk;Lee, Woong-Hee
    • Proceedings of the Ginseng society Conference
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    • 1998.06a
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    • pp.208-215
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    • 1998
  • Ginseng has been used in maintaining physical vitality all over the East Asian countries and recently its metabolism and actions on neurologic, cardiovascular and endocrinologic systems are being elucidated. Korean red ginseng (KRG) has been used in various aliments, and to prove its efficacy icy erectile dysfunction an international study on Asians other than Korean was performed. Patients with borderline organic and psychogenic erectile dysfunction were included. KRG were given daily, and placebos were given as controls. Treatment lasted a total of 3 months. Surveys including libido, erectile potency, the sexual satisfactions were given. Serum testosterone and erectile function study were taken. Among the 23 patients with KRG, 18 patients were followed. Four had diabetes, 2 hypertension, 3 hyperchole, iterolemia, 1 low testosterone,4 psychogenic, and 4 idiopathic. In 10 patients with placebo, 7 were followed for more than three months. The clinical efficacy of KRG was 66.7% on objective Questionnaire and 72.2% on subjective analysis. When KRG were given, all parameters surveyed have shown improvements compared to the controls. Serum testosterone Bevels were normalized in 2 patients with KRG, whose serum testosterone levels were reduced from prestudy. When the erectile functions after audiovisual stimuli evaluated using Rigiscan in 6 patients with KRG,4 showed rigidity move than 70oyc. One patient reported constipation, and 2 gastric up-sets in the KRG group. In conclusion, KRG has beneficiary action on male erectile capabilities with minimal side effects. Thus KRG has been proven effective in Koreans, and a result on other Asians is pending. The exact action mechanism and the active ingredients in KRC need to be itudied.

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Numeric Analysis of 2-Dimensional Nonlinear Viscous Free-Surface Wave Problems (점성을 고려한 2차원 비선형 자유표면파 문제의 수치해석)

  • Y.H. Kim
    • Journal of the Society of Naval Architects of Korea
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    • v.30 no.2
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    • pp.98-111
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    • 1993
  • Two-dimensional nonlinear free-surface wave problems are analyzed with consideration of viscosity. Navier-Stokes equation and continuity equation are solved by the application of Finite Analytic Method, and MAC scheme is used far the treatment of free surface. Surface tension effect is also considered and laminar flow is assumed. The free-surface waves in shallow water, the flows around a vortex-pair with free surface and the wave ahead of a rectangular body are simulated to test the present numerical scheme. In the shallow water problem, viscous effect due to the friction on the bottom is observed. In the second problem, the approach of a vortex-pair to the free surface is simulated to examine the interaction of vortex-pair with the free surface. In the third problem, the wave ahead of a semi-infinite floating body is simulated.

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A Reconsidering on Setting for Philosophy and Curriculum Development in Nursing Education (간호교육과정틀에 관한 소고 -돌봄과학과 보건정책 중심으로-)

  • Kim Myung-Ja
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.2 no.1
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    • pp.55-66
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    • 1995
  • The goals of nursing education, and the bases for evaluating them depend on the goals of nursing practice. In order to prepare for the coming twenty first century and the meet changing societal demands and health needs, it is necessary to develop a new conceptual framework for future nursing education. While hospitals will still be in significant components of the health care system, will no longer be central focus or dominant influence. Health care services will be more usually delivered at community base. The nursing education required by that new approach must provide for reconsidered about a concept of caring as nursing curriculum. The changes in health care delivery that have occured, now being proposed, for nursing education undergoing its own changes. So the philosophy and objectives of education meed to reconsidering about the caring concept and general nursing. Nurse educators must prepare students to practic in condition of constant change. At the same time nurse educators must emphasize preparation about that. The practice of science of caring in nursing draws on a basic knowledge of the behavioral knowledge, biophysical processes, pathological processes, nursing skills and procedures and various treatment regimes and problem solving to help decision making in nursing situations. The concept of care is probably one of the least understood ideas used by professional and nonprofessional people, yet it is probably one of the most improtant concepts to be understood by nursing. Human caring and human relationships are closely interrelated. Humn caring remains an essential dimension of professional work and the science of caring as essental to the discipline of nursing. It is expected that the objectives of nursing education will be accomplished when the course and content of the curriculum are based on this conceptual framework. One recurrent education goal with some consistency is that of equipping the student with the necessary skills to live effectively and productivly in the world of tomorrow. In the new vision we are developing, professional education must also include exposure to liberal arts, encouragement of critical thinking, and a moral context for advanced professional education that is based upon a contextual health policy and caring science educational model.

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Influence of Supply Chain Configuration and Annual Sales on Performance in the Development of Automotive E/E Parts (자동차 전장부품 개발에서 공급사슬형상, 기업 매출 특성이 성과에 미치는 영향)

  • Song, Min;Hwang, Seung-June;Park, Geun-Wan;Baik, Jae-Won
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.4
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    • pp.10-20
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    • 2017
  • The proportion of software in the automotive industry is steadily increasing due to the rapid technological development of automobile E/E parts. Because the automotive E/E technology is now on the basis of intelligent automobile and advanced safety automobile technology. The purpose of this study is to investigate the effect of organizational capability (organizational resource capability and management capability), process capability (process capability, customer Requirement management capability), performance dimension (motivation, participation level). In this study, we conducted questionnaires and statistical analysis on engineers (members of the Korea Advanced Automotive Technology Association) who perform research and development activities in the R&D organization of the automotive E/E part in South Korea. ANOVA is applied for the verification of the difference in performance measured by organizational capability, process maturity, and motivation participation level according to company characteristics (level of processing : supply chain configuration, annual sales, total SW development ratio). According to the results of this study, in order to improve the performance of ASPICE or ISO 26262-related consulting project, a different consulting approach strategy considering the characteristics of organization and personnel is needed. In summary, the analysis results for the three main treatment levels are as follows. The difference in organizational capacity, process capability and performance was found to be statistically significant according to supply chain configuration and annual sales, but it was found that the difference of response according to the proportion of total SW was not significant.

Thin-Walled Beam Model for Structural Analysis of SWATH (SWATH의 구조해석을 위한 Thin-Walled Beam 모델)

  • Sang-Gab Lee;Yoon-Sup Ko
    • Journal of the Society of Naval Architects of Korea
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    • v.30 no.4
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    • pp.136-152
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    • 1993
  • This study is intended to develop an accurate and efficient, analytical thin-walled beam model, and to analyze overall behavior of SWATH ship under repeated overloads. SWATH ship is idealized to a simple thin-walled beam of channel type. An analytical beam model is formulated by the stress component with geometrically(fully) nonlinear thin-walled beam and treated numerically by the Finite Element Method. An efficient cyclic plasticity model is also included, suitable for material nonlinear behavior under complex loading conditions. The local stress distribution can be very exactly represented and the material yielding propagation, easily traced. In addition, the local treatment of the effect of shear deformation improves the representation of deformation and shear stress distribution along the section contour. It is desirable to use the analytical thin-walled beam at initial design stage, and is needed to improve the practical thin-walled beam model advancing the current approach.

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Intracisternal Administration of Voltage Dependent Calcium Channel Blockers Attenuates Orofacial Inflammatory Nociceptive Behavior in Rats

  • Won, Kyoung-A.;Park, Sang-H.;Kim, Bo-K.;Baek, Kyoung-S.;Yoon, Dong-H.;Ahn, Dong-K.
    • International Journal of Oral Biology
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    • v.36 no.2
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    • pp.43-50
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    • 2011
  • Voltage dependent calcium channel (VDCC), one of the most important regulator of $Ca^{2+}$ concentration in neuron, play an essential role in the central processing of nociceptive information. The present study investigated the antinociceptive effects of L, T or N type VDCC blockers on the formalin-induced orofacial inflammatory pain. Experiments were carried out on adult male Sprague-Dawley rats weighing 220-280 g. Anesthetized rats were individually fixed on a stereotaxic frame and a polyethylene (PE) tube was implanted for intracisternal injection. After 72 hours, 5% formalin ($50 \;{\mu}L$) was applied subcutaneously to the vibrissa pad and nociceptive scratching behavior was recorded for nine successive 5 min intervals. VDCC blockers were administered intracisternally 20 minutes prior to subcutaneous injection of formalin into the orofacial area. The intracisternal administration of 350 or $700{\mu}g$ of verapamil, a blocker of L type VDCC, significantly decreased the number of scratches and duration in the behavioral responses produced by formalin injection. Intracisternal administration of 75 or $150 \;{\mu}g$ of mibefradil, a T type VDCC blocker, or 11 or $22\; {\mu}g$ of cilnidipine, a N type VDCC blocker, also produced significant suppression of the number of scratches and duration of scratching in the first and second phase. Neither intracisternal administration of all VDCC blockers nor vehicle did not affect in motor dysfunction. The present results suggest that central VDCCs play an important role in orofacial nociceptive transmission and a targeted inhibition of the VDCCs is a potentially important treatment approach for inflammatory pain originating in the orofacial area.

A Survey on the Injuries of Mixed Martial Arts Athletes : for Oriental Sports Medicine (스포츠한의학의 활용을 위한 종합격투기 상해 분석)

  • Park, Ji-Hun;Soh, Kab-Seog;Park, Jung-Hyun;Nam, Jong-Kyoung;Kim, Ho-Jun;Lee, Myeong-Jong
    • Journal of Korean Medicine Rehabilitation
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    • v.18 no.4
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    • pp.217-230
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    • 2008
  • Objectives : The purpose of this study was to investigate the type, sites and period of injuries in Mixed Martial Arts. Methods : The questionnaire composed of 26 items was used as the research tool for this study. The respondents were 84 athletes of Mixed Martial Arts who participated in Spirit MC Amateur League in September, 2007. Data analysis use chi-square examination by SPSS$^{(R)}$ 12.0 program. Results : 1. Frequently, strikers are damaged at face and waist, grapplers are damaged at knee and waist. 2. Frequently, beginers are damaged at muscle and tendon, experts are damaged at bone and joint. 3. Age, career, specialty and injured type have significant correlations. 4. Age, career, training time and concern response have significant correlations. 5. Oriental medical treatment are friendly but not well-known to the athletes. Conclusions : Injuries of Mixed Martial Arts is multifactorial, so approach of athlete's individuality is important.

Indirect Inguinal Hernia in Pediatric Patients (소아의 간접 서혜부 탈장)

  • Chung, Sang-Young
    • Advances in pediatric surgery
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    • v.16 no.2
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    • pp.101-107
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    • 2010
  • Herniorrhaphy of Indirect inguinal hernia (IIH) is one of the most frequently performed surgical procedures in children. The overall incidence of inguinal hernias in childhood ranges from 0.8 to 4.4 %. The incidence is up to 10 times higher in boys than girls, especially much higher in premature infants. IIHs in children are basically an arrest of embryologic development rather than an acquired weakness, which explains the increased incidence in premature infants. In normal development, the processus vaginalis closes, obliterating the peritoneal opening of the internal ring between 36th and 40th week of gestation. This process is often incomplete, leaving a small patent processus in many newborns. However, closure continues postnatally, and the rate of patency is inversely proportional to age of the child. The presence of a patent processus vaginalis is a necessary but not sufficient variable in developing a congenital IIH. In other words, all congenital IIHs are preceded by a patent processus vaginalis, but not all patent processus vaginalis go on to become IIHs. The overall incidence of IIH in population is approximately 1 to 2 % and the incidence of a processus vaginalis is approximately 12 to 14%, clinically appreciable IIH should develop in approximately 8 to 12 % of patients with a patent processus vaginalis. Although the classic open inguinal hernia repair remains the gold standard for most pediatric surgeons, laparoscopic repair is being performed in many centers. Like open technique, laparoscopic technique is fundamentally a high ligation of the indirect hernia sac with or without internal ring ligation. The advantages of laparoscopic approach include the ease of examining the contralateral internal ring, the avoidance of access damage to vas and vessels during mobilization of cord, decreased operative time, and an ability to identify unsuspected direct or femoral hernias. Almost all groin hernias in children are IIHs and occur as a result of incomplete closure of processus vaginalis. The treatment is repair by high ligation of hernia sac, which can be done by an open or laparoscopic technique. The contralateral side can be explored by laparoscopy or left alone, open exploration is no longer indicated due to potential risk of infertility.

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Analysis of Complication in Pediatric Patients with Hickman Catheters (히크만 카테터를 삽입한 소아 환자에서 발생한 합병증 분석)

  • Kim, Tae-Hoon;Kim, Dae-Yeon;Cho, Min-Jeong;Kim, Seong-Chul;Kim, In-Koo
    • Advances in pediatric surgery
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    • v.16 no.1
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    • pp.25-31
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    • 2010
  • Hickman catheters are tunneled central venous catheters used for long-term venous access in children with malignancies. The appropriate management for various kinds of catheter related complications has become a major issue. We retrospectively analyzed the clinical, demographic, and surgical characteristics in 154 pediatric hemato-oncology patients who underwent Hickman catheter insertion between January 2005 and December 2009. There were 92 boys and 62 girls. The mean age at surgery was $7.6{\pm}5.1$ years old. The mean operation time was $67.4{\pm}21.3$ minutes and C-arm fluoroscopy was used in 47(30.5 %). The causes of Hickman catheter removal were termination of use in 82 (57.3 %), catheter related bloodstream infection in 44(30.8 %), mechanical malfunction in 11(7.7 %), and accidents in 6(4.2 %). Univariate and multivariate analysis for associated factors with catheter related bloodstream infection showed that there were no statistically significant associated factors with catheter related infection complications. All cases except two showed clinical improvement with catheter removal and relevant antibiotics treatment. The mean catheter maintenance period in patients of catheter removal without complications was $214.9{\pm}140.2$ days. And, The mean catheter maintenance period in patients of late catheter related bloodstream infection was $198.0{\pm}116.0$ days. These data suggest that it is important to remove Hickman catheter as soon as possible after the termination of use. When symptoms and signs of complications were noticed, prompt diagnostic approach and management can lead to clinical improvements.

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