• 제목/요약/키워드: treatment approach

검색결과 3,135건 처리시간 0.032초

Hook Plate Fixation for Isolated Greater Tuberosity Fractures of the Humerus

  • Lee, Kyoung-Rak;Bae, Ki-Cheor;Yon, Chang-Jin;Cho, Chul-Hyun
    • Clinics in Shoulder and Elbow
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    • 제20권4호
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    • pp.222-229
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    • 2017
  • Background: The purpose of this study was to investigate the outcomes after fixation using a 3.5-mm locking compression plate (LCP) hook plate for isolated greater tuberosity (GT) fractures of the proximal humerus. Methods: We evaluated the postoperative radiological and clinical outcomes in nine patients who were followed up at least 1 year with isolated GT fractures. Using the deltopectoral approach, we fixed the displaced GT fragments with a 3.5-mm LCP hook plate (Synthes, West Chester, PA, USA). Depending on the fracture patterns, the hook plate was fixed with or without augmentation using either tension suture or suture anchor fixation. Results: All the patient showed successful bone union. The mean time-to-union was 11 weeks. The radiological and clinical outcomes at the final follow-up were generally satisfactory. The mean visual analogue scale for pain, the University of California at Los Angeles score, the American Shoulder and Elbow Surgeons score, and the subjective shoulder value were 1.4, 30.3, 84.3, and 82.2%, respectively. The mean active forward flexion, abduction, external rotation, and internal rotation of the shoulder were $156.7^{\circ}$, $152.2^{\circ}$, $61.1^{\circ}$, and the 10th thoracic vertebral level, respectively. Only one patient presented with a postoperative complication of shoulder stiffness. The patient was treated through arthroscopic capsular release on the 5th postoperative month. Conclusions: We conclude that fixation using 3.5-mm LCP hook plates for isolated GT fractures of the proximal humerus is a useful treatment method that provides satisfactory clinical and radiological outcomes.

The Economic Burden of Epilepsy in Korea, 2010

  • Jung, Jaehun;Seo, Hye-Young;Kim, Young Ae;Oh, In-Hwan;Lee, Yo Han;Yoon, Seok-Jun
    • Journal of Preventive Medicine and Public Health
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    • 제46권6호
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    • pp.293-299
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    • 2013
  • Objectives: The purposes of this study were to evaluate the prevalence of epilepsy and to estimate the cost of epilepsy in Korea, 2010. Methods: This study used a prevalence based approach to calculate the cost of epilepsy. Claims data from the Korean national health insurance and data from the Korea health panel, the Korea National Statistical Office's records of causes of death, and labor statistics were used to estimate the cost of epilepsy. Patients were defined as those who were hospitalized or visited an outpatient clinic during 2010 with a diagnosis of epilepsy (International Classification of Diseases 10th revision codes G40-G41). Total costs of epilepsy included direct medical costs, direct non-medical cost and indirect costs. Results: The annual prevalence of treated epilepsy was 228 per 100 000 population, and higher in men. The age-specific prevalence was highest for teenagers. The total economic burden of epilepsy was 536 billion Korean won (KW). Indirect cost (304 billion KW) was 1.3 times greater than direct cost (232 billion KW). By gender, the male (347 billion KW) were more burdened than the female (189 billion KW). The estimated cost in young age younger than 20 years old was 24.5% of the total burden of epilepsy. Conclusions: A significant portion of the economic burden of epilepsy is borne by people in young age. To reduce the economic burden of epilepsy, effective prevention and treatment strategies are needed.

저근백피 추출물이 유선암 세포에서의 신생혈관 미치는 영향 (Effects on Inhibition of Angiogenesis in MCF-7 Cells by the Aqueous Root Extract of Ailanthus Altissima)

  • 정지학;윤용갑;전병훈;박혜련;안원근
    • 동의생리병리학회지
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    • 제18권6호
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    • pp.1613-1616
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    • 2004
  • The cellular response to hypoxia is controlled to a large degree by the transcription factor Hypoxia-inducible factor-1(HIF-1). HIF-1 is a transcription factor that is activated by hypoxia and plays a critical role in the development of the cancer phenotype. HIF-1 regulates transcription of a number of genes crucial for tumor survival under hypoxic conditions, including vascular endothelial growth factor(VEGF), erythropoietin(Epo) and several glycolytic enzymes. Tumors in which hypoxia can not induce HIF-1 transcriptional activity remain small and fail to metastasize. In this study, we examined whether aqueous root extract of Ailanthus altissima (REA) downregulate HIF-1, VEGF and p53, and raise the possibility that depletion of these proteins and the anti proliferative activities of REA have any effects on inhibition of angiogenesis in MCF-7 cells. Pharmacologic targeting of specific signal transduction pathways related to oncogenic transformation is a promising approach in cancer treatment. Therefore, REA could be a candidate drug for further clinical development.

Intestinal Helminthic Infections Diagnosed by Colonoscopy in a Regional Hospital during 2001-2008

  • Do, Kyong-Rock;Cho, Young-Seok;Kim, Hyung-Keun;Hwang, Byung-Hee;Shin, Eun-Jung;Jeong, Hae-Bin;Kim, Sung-Soo;Chae, Hiun-Suk;Choi, Myung-Gyu
    • Parasites, Hosts and Diseases
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    • 제48권1호
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    • pp.75-78
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    • 2010
  • The present study investigated characteristics of 24 parasite infection cases detected during colonoscopy in a regional hospital from January 2001 to December 2008. Sixteen patients were confirmed with Trichuris trichiura infection, 6 patients were with Ascaris lumbricoides infection, 1 patient with Enterobius vermicularis infection, and 1 patient with Anisakis infection. Among them, 7 patients (43.8%) were asymptomatic. Colonoscopy findings were normal in 18 patients (75.0%). Among the patients with T. trichiura infection, colonoscopy showed several erosions in 2 patients (8.3%) and non-specific inflammation of the affected segment of the colon in 3 patients (12.5%). In 1 patient with anisakiasis, colonoscopy revealed a markedly swollen colonic wall. Stool examinations were performed before treatment in 7 patients (29.2%) and were all negative for parasite eggs or worms. These results suggest that colonoscopy is a useful diagnostic approach for parasitic infections even for asymptomatic patients and for patients with negative stool examinations.

총상으로 인한 경추부 및 척수손상: 증례 보고 (A Gunshot Wounds to the Cervical Spine and the Cervical Spinal Cord: A Case Report)

  • 팽성화
    • Journal of Trauma and Injury
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    • 제25권2호
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    • pp.57-62
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    • 2012
  • Gunshot wounds are rare in Korea, but they have tended to increase recently. We experienced an interesting case of penetrating gunshot injuries to the cervical spine with migration the fragments of the bullet within the dural sac of the cervical spine, so discuss the pathomechanics, treatment and complications of gunshot wounds to the spine and present a review of the literature. A 38-year-old man who had tried to commit suicide with a gun was admitted to our hospital with a penetrating injury to the anterior neck. the patient had quadriplegia. A Computed tomography (CT) scan and 3-dimensional CT of the spine showed destruction of the left lateral mass and lamina of the 5th cervical vertebra; the bullet and fragments were found at the level of the 5th cervical vertebra. The posterior approach was done. A total laminectomy and removal of the lateral mass of the 5th cervical vertebrae were performed, and bone fragments and pellets were removed from the spinal canal, but an intradurally retained pellets were not totally removed. A dural laceration was noted intraoperatively, and CSF leakage was observed, so dura repair was done watertightly with prolene 6-0. The dura repair site was covered with fibrin glue and Tachocomb$^{(R)}$. Immediately, a lumbar drain was done. Radiographs included a postoperative CT scan and X-rays. The postoperative neurological status of the patient was improved compared with the preoperative neurological status. however, the patients developed symptoms of menigitis. He received lumbar drainage(200~250 cc/day) and ventilator care. After two weeks, panperitonitis due to duodenal ulcer perforation was identified. Finally, the patient died because of sepsis.

도시유역 저류형 시스템 설계를 위한 CSOs 산정 (Storm-Water CSOs for Reservoir System Designs in Urban Area)

  • 조덕준;김명수;이정호;박무종;김중훈
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2005년도 학술발표회 논문집
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    • pp.1199-1203
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    • 2005
  • Combined sewer overflows(CSOs) are themselves a significant source of water pollution. Therefore, the control of urban drainage for CSOs reduction and receiving water quality protection is needed. Examples in combined sewer systems include downstream storage facilities that detain runoff during periods of high flow and allow the detained water to be conveyed by an interceptor sewer to a centralized treatment plant during periods of low flow. The design of such facilities as stormwater detention storage is highly dependant on the temporal variability of storage capacity available(which is influenced by the duration of interevent dry periods) as well as the infiltration capacity of soil and recovery of depression storage. As a result, a contiunous approach is required to adequately size such facilities. This study for the continuous long-term analysis of urban dranage system used analytical Probabilistic model based on derived probability distribution theory. As an alternative to the modeling of urban drainage system for planning or screening level analysis of runoff control alternatives, this model have evolved that offer much ease and flexibility in terms of computation while considering long-term meteorology. This study presented rainfall and runoff characteristics or the subject area using analytical Probabilistic model. Runoff characteristics manifasted the unique characteristics of the subject area with the infiltration capacity of soil and recovery of depression storage and was examined appropriately by sensitivity analysis. This study presented the average annual COSs and number of COSs when the interceptor capacity is in the range 3xDWF(dry weather flow). Also, calculated the average annual mass of pollutant lost in CSOs using Event Mean Concentration. Finally, this study presented a dicision of storage volume for CSOs reduction and water quality protection.

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하천의 프랙탈 특성을 고려한 지형학적 순간단위도 개발(I) (Development of a GIUH Model Based on River Fractal Characteristics)

  • 홍일표;고재웅
    • 한국수자원학회논문집
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    • 제32권5호
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    • pp.565-577
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    • 1999
  • 프랙탈 기하학은 불규칙적이고 복잡한 자연 현상을 수학적으로 나타낼 수 있는 방법을 제시해 줄 수 있으며, 자기상사성을 가지고 있는 하천의 형상을 비롯한 하도망의 구성은 프랙탈 차원을 가지고 있는 프랙탈 현상이라 할 수 있다. GIUH란 유역의 수문학적 응답인 IUH에 하천의 지형학적인 특성을 적용한 강우-유출 모형으로, Horton의 차수비를 이용하여 지형학적인 특성을 반영할 수 있으며 하천 유역에서 프랙탈 차원은 길이비, 면적비, 분기비 등 Horton의 차수비를 이용하여 산정할수 있다. 프랙탈 GIUH 모형을 제시하였다. 프랙탈 GIUH 모형은 Rosso(1984)가 제시한 GIUH-Nash 모형의 형상계수와 규모계수 등의 매개변수 산정시 유역의 자기상사성을 대변할 수 있는 프랙탈 차원을 직접 적용하였으며, 하천의 길이비와 분기비 만의 함수로 나타내었다.

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$Cu_2ZnSnS_4$ Thin Film Absorber Synthesized by Chemical Bath Deposition for Solar Cell Applications

  • Arepalli, Vinaya Kumar;Kumar, Challa Kiran;Park, Nam-Kyu;Nang, Lam Van;Kim, Eui-Tae
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2011년도 추계학술발표대회
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    • pp.35.1-35.1
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    • 2011
  • New photovoltaic (PV) materials and manufacturing approaches are needed for meeting the demand for lower-cost solar cells. The prototypal thin-film photovoltaic absorbers (CdTe and $Cu(In,Ga)Se_2$) can achieve solar conversion efficiencies of up to 20% and are now commercially available, but the presence of toxic (Cd,Se) and expensive elemental components (In, Te) is a real issue as the demand for photovoltaics rapidly increases. To overcome these limitations, there has been substantial interest in developing viable alternative materials, such as $Cu_2ZnSnS_4$ (CZTS) is an emerging solar absorber that is structurally similar to CIGS, but contains only earth abundant, non-toxic elements and has a near optimal direct band gap energy of 1.4~1.6 ev and a large absorption coefficient of ${\sim}10^4\;cm^{-1}$. The CZTS absorber layers are grown and investigated by various fabrication methods, such as thermal evaporation, e-beam evaporation with a post sulfurization, sputtering, non-vacuum sol-gel, pulsed laser, spray-pyrolysis method and electrodeposition technique. In the present work, we report an alternative method for large area deposition of CZTS thin films that is potentially high throughput and inexpensive when used to produce monolithically integrated solar panel modules. Specifically, we have developed an aqueous chemical approach based on chemical bath deposition (CBD) with a subsequent sulfurization heat treatment. Samples produced by our method were analyzed by scanning electron microscopy, X-ray diffraction, transmission electron microscopy, absorbance and photoluminescence. The results show that this inexpensive and relatively benign process produces thin films of CZTS exhibiting uniform composition, kesterite crystal structure, and good optical properties. A preliminary solar cell device was fabricated to demonstrate rectifying and photovoltaic behavior.

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수학 문제만들기 활동이 문제해결력과 학습 태도에 미치는 효과 (The Effects of the Mathematical Problem Generating Program on Problem Solving Ability and Learning Attitude)

  • 정성건;박만구
    • 한국초등수학교육학회지
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    • 제14권2호
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    • pp.315-335
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    • 2010
  • 본 연구는 수학 교육과정을 근거로 개발한 문제만들기 활동 자료를 이용하여 학생들로 하여금 문제만들기 활동을 하도록 하여 문제해결력과 수학 학습 태도에 미치는 효과를 알아보았다. 실험반은 서울시의 J초등학교 5학년 2개 학급을 선정하여 문제만들기를 실시하고 비교반은 같은 기간 동안 문제만들기를 실시하지 않고 일반적인 교수 학습만을 실시하였다. 사전 사후 검사로서는 문제해결력 검사와 수학 학습 태도 검사를 실시하여 각각 t검증 하였다. 연구 결과 첫째, 수학 문제만들기를 적용한 반이 문제해결력 향상에 있어서 유의미한 효과를 보였다. 둘째, 수학 문제만들기를 적용한 반의 수학 학습 태도에 긍정적인 효과를 보였다. 결론으로, 학생들은 문제만들기를 통하여 문제를 충분히 이해하고 분석하게 되어 어려운 문제를 해결할 수 있는 문제해결력을 갖게 되고, 학생들이 스스로 문제를 만들고 재구성하면서 수학 학습에 적극적으로 참여하게 되어 수학에 대한 태도도 긍정적으로 변화시킨 것으로 볼 수 있다.

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재발성 음경지속발기증 1례 (A Case Report of treating Stuttering Priapism)

  • 박성환;백선호;한수련;안영민;안세영;이병철
    • 대한한방내과학회지
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    • 제32권1호
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    • pp.136-143
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    • 2011
  • Priapism is a persistent penile erection that continues for more than 4 hours beyond, or is unrelated to, sexual stimulation. Because priapism is a medical emergency, all patients with priapism should be evaluated and treated urgently. Subtypes of priapism are ischemic, non-ischemic and stuttering priapism. Stuttering type is a recurrent form of ischemic priapism in which unwanted painful erections occur repeatedly with intervening periods of detumescence. The etiology of this type is often idiopathic and the treatments are still not clearly established. We present one case of stuttering priapism which occurred after suppression of his sexual desire. A 23-year-old man visited our clinic complaining of recurrent pain and erections persisting for about 5 weeks. We performed evaluation and confirmed the diagnosis of Rigid swollen penis. Jibaekjihwang-tang gamibang (ZhiBaiDihuang-Tang Jiaweifang) was administerd to the patient for 9 days. After the treatment, duration of erections and pain showed remarkable improvements. This will be recorded as the first case report of treating priapism with a Korean medical approach and suggests that Korean medicine therapy can be efficient to treat priapism.