• 전자공학회논문지CI
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• 제39권3호
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• pp.32-43
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• 2002

본 논문에서는 신경망에 기반한 디지털 신호를 위한 패턴분류 시스템을 제안한다. 제안하는 시스템은 두 가지 신경망 모델로 구성된다. 첫 번째 부분은 특징 추출의 역할을 하는 웨이블릿 신경망이다. 이 부분을 위해 기존의 웨이블릿 신경망 모델들을 비교한 후, 특징 추출을 위한 새로운 웨이블릿 신경망 모델을 제안한다. 다른 부분은 패턴 분류를 위한 웨이블릿 신경망이다. 패턴 분류에 적용하기 위해 기존의 웨이블릿 신경망 구조를 수정하고 학습 방법을 제안한다. 패턴 분류 웨이블릿 신경망의 입력은 특징 추출 신경망의 은닉노드의 연결강도, 확장 및 이동 파라미터로 구성되었다. 또 출력은 특징 추출 신경망의 입력 신호가 속한 부류를 나타낸다. 제안한 시스템을 EEG 신호를 주파수에 따라서 분류하는 문제에 적용하였다.

• 한방재활의학과학회지
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• 제23권4호
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• pp.129-141
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• 2013

Objectives The aim of this review is to investigate clinical studies for manual therapy on Temporomandibular Joint Disorder and to propose for the better method of studies in the future. Methods We investigated recent clinical studies for manual therapy on Temporomandibular Joint Disorder via searching Pubmed, KISS, KISTI, KERIS, KMBASE and National Assembly Library. 21 domestic and overseas articles were analyzed and the journals, the authors, the published years, countries, methods, periods, techniques of chiropractic, outcome measures, and purpose of those articles were examined. Results Studies on manual therapy were mainly published via Cranio. The diagnostic criteria that most frequently adopted in the overseas articles were research diagnostic criteria for temporomandibular disorders, The technique of chiropractic that most frequently adopted in the articles was passive traction and translation of TMJ. Many of the studies were researched for effectiveness of the manual therapy as the secondary treatment. Conclusions Reviewing the recent clinical studies for manual therapy on temporomandibular joint disorder and figuring out the strong points and weak points of those studies are necessary to future studies. It is anticipated that this review would benefit the in-depth treatments for temporomandibular joint disorder in terms of Korean medicine.

• 한국수학교육학회지시리즈A:수학교육
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• 제56권1호
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• pp.63-80
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• 2017

By analysing the examination papers from third grade high school students, we classified the errors occurred in the problem solving process of high school 'Geometry and Vectors' into several types. There are five main types - (A)Insufficient Content Knowledge, (B)Wrong Method, (C)Logical Invalidity, (D)Unskilled Expression and (E)Interference.. Type A and B lead to an incorrect answer, and type C and D cannot be distinguished by multiple-choice or closed answer questions. Some of these types are classified into subtypes - (B1)Incompletion, (B2)Omitted Condition, (B3)Incorrect Calculation, (C1)Non-reasoning, (C2)Insufficient Reasoning, (C3)Illogical Process, (D1)Arbitrary Symbol, (D2)Using a Character Without Explanation, (D3) Visual Dependence, (D4)Symbol Incorrectly Used, (D5)Ambiguous Expression. Based on the these types of errors, answers of each problem was analysed in detail, and proper ways to correct or prevent these errors were suggested case by case. When problems that were used in the periodical test were given again in descriptive forms, 67% of the students tried to answer, and 14% described flawlessly, despite that the percentage of correct answers were higher than 40% when given in multiple-choice form. 34% of the students who tried to answer have failed to have logical validity. 37% of the students who tried to answer didn't have enough skill to express. In lessons on curves of secondary degree, teachers should be aware of several issues. Students are easily confused between 'focus' and 'vertex', and between 'components of a vector' and 'coordinates of a point'. Students often use an undefined expression when mentioning a parallel translation. When using a character, students have to make sure to define it precisely, to prevent the students from making errors and to make them express in correct ways.

• Investigative Magnetic Resonance Imaging
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• 제21권4호
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• pp.223-232
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• 2017

Purpose: To report the use of multiband accelerated echo-planar imaging (EPI) for resting-state functional MRI (rs-fMRI) to achieve rapid high temporal resolution at 3T compared to conventional EPI. Materials and Methods: rs-fMRI data were acquired from 20 healthy right-handed volunteers by using three methods: conventional single-band gradient-echo EPI acquisition (Data 1), multiband gradient-echo EPI acquisition with 240 volumes (Data 2) and 480 volumes (Data 3). Temporal signal-to-noise ratio (tSNR) maps were obtained by dividing the mean of the time course of each voxel by its temporal standard deviation. The resting-state sensorimotor network (SMN) and default mode network (DMN) were estimated using independent component analysis (ICA) and a seed-based method. One-way analysis of variance (ANOVA) was performed between the tSNR map, SMN, and DMN from the three data sets for between-group analysis. P < 0.05 with a family-wise error (FWE) correction for multiple comparisons was considered statistically significant. Results: One-way ANOVA and post-hoc two-sample t-tests showed that the tSNR was higher in Data 1 than Data 2 and 3 in white matter structures such as the striatum and medial and superior longitudinal fasciculus. One-way ANOVA revealed no differences in SMN or DMN across the three data sets. Conclusion: Within the adapted metrics estimated under specific imaging conditions employed in this study, multiband accelerated EPI, which substantially reduced scan times, provides the same quality image of functional connectivity as rs-fMRI by using conventional EPI at 3T. Under employed imaging conditions, this technique shows strong potential for clinical acceptance and translation of rs-fMRI protocols with potential advantages in spatial and/or temporal resolution. However, further study is warranted to evaluate whether the current findings can be generalized in diverse settings.

• 대한기계학회논문집A
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• 제27권12호
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• pp.2039-2046
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• 2003

Storage tank filled with fluid has unique dynamic characteristics compared to general structures, due to the interaction between fluid and structure. The oscillation of the fluid surface caused by external forces is called sloshing, which occurs in moving vehicles with contained liquid masses, such as trucks, railroad cars, aircrafts, and liquid missles. In this study, the evaluation method for the reduction of sloshing, the optimized size and location of wing and diaphragm baffles are suggested based on the experimental results. The experimental device can simulate the translation motion. A rectangular tank and various baffles are fabricated to study on the sloshing characteristics. The forces measured using the load cell at tank wall and those are compared with each other through the Fourier transformation for various conditions. The study of the sloshing of the rectangular tank equipped with baffles is conducted under the same conditions with non-baffled rectangular tank experiment. From the experimental results, the sloshing reduction effect by the baffles is observed. In conclusion in case of diaphragm baffles, the optimized size ratio of the width of baffle to the water height is 0.44 and the installation location has no effect to the damping of sloshing. In case of wing baffles, the optimized size ratio of the width of baffle to the length of a rectangular tank is 0.1 and the optimized location ratio of the baffle to the water height is 0.9.

• 한국가금학회지
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• 제35권1호
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• pp.39-55
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• 2008

Like the other herpesviruses, the virion of MDV consists of an envelope, which surrounds an amorphous tegument. Within the tegument, and icosahedral capsid encloses a linear double-stranded DNA core. Although the genome structure of MDV indicates that it is an ${\alpha}-herpesvirus$ like herpes simplex and varicella-zoster viruses, biological properties indicate MDV is more akin to the ${\gamma}-herpesvirus$ group, which includes Epstein-Barr and Kaposi's sarcoma herpesviruses. These herpesviruses replicate lytically in lymphocytes, epithelial and fibroblastic cells, and persist in lymphoblastoid cells. MDV has a complex life cycle and uses two means of replication, productive and non-productive, to exist and propagate. The method of reproduction changes according to a defined pattern depending on changes in virus-cell interactions at different stages of the disease, and in different tissues. Productive (lytic) interactions involve active invasion and take-over of the host cell, resulting in the production of infectious progeny virions. However, some herpesviruses, including MDV, can also establish a non-productive (abortive) infection in certain cell types, resulting in production of cell-associated progeny virus. Non-productive interactions represent persistent infection, in which the viral genome is present but gene expression is limited, there is no structural or regulatory gene translation, no replication, no release of progeny virions and no cell death. Reactivation of the virus is rare, and usually the infectious virus can be re-isolated only after cultivation in vitro. MDV establishes latency in lymphoid cells, some of which are subsequently transformed. In this review article, recent knowledges of the pathogenesis mechanisms followed by MDV infection to sensitive cells and chickens are discussed precisely.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6415-6421
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• 2012

Background: Canine mammary gland tumors (CMGTs) are the most common tumor found in bitches. Changes in HER-2/neu genes in human breast cancer (HBC) lead to decrease in disease-free survival (DFS) and overall survival rate (OSR). Previous studies have demonstrated that the biological behavior of malignant mammary gland tumors (MMGTs) is similar to that of HBC. The present study aimed at evaluating the relationship between overexpression of HER-2/neu and clinicopathological features in MMGTs to represent a model of prognostic factors for HBC. Materials and Method: The clinicopathological data of 35 MMGTs were obtained. Immunohistochemical staining with HER-2, Ki-67 and CD34 markers was conducted with sections from paraffin-embedded blocks. According to standard protocols, histological type, grade, margin status, lymphovascular invasion (LVI), HER-2/neu score, proliferation rate and microvessel density (MVD) of tumors were determined and the association of HER-2/neu overexpression with these parameters was assessed statistically. Results: The IHC results showed that 12 (34.3%) cases were HER-2/neu positive. Statistical analyses indicated a significant relationship between HER-2 positivity and tumor grade (p=0.043), which also was demonstrated with cancer stage (p=0.035), tumor margin involvement (p=0.016), proliferation index (p=0.001) and MVD (p=0.001); however, there was no statistical relationship between LVI and tumor size. Overexpression of the HER-2/neu gene in MMGTs results in similar biological behavior as that of HBC; as a result, these tumors have can be considered to have important similarities in clinicopathological characteristics. Conclusions: MMGTs can be regarded as an HBC animal model. Further studies in this field would result in new treatments that could be beneficial for both dogs and humans.

• 전자공학회논문지CI
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• 제40권2호
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• pp.1-8
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• 2003

본 논문에서는 컬러 영상에서 Dominant 컬러쌍 정보를 이용한 객체기반 영상검색 기법을 제안한다. 기존의 대부분 연구에서는 관심있는 객체를 포함한 영상 전체에 대해 특징값을 추출하여 유사 영상을 검색함으로써 배경으로 인해 검색 성능이 나빠지는 단점이 있었다. 본 논문에서는 관심있는 객체 정보만 질의로 사용하고 DB내의 영상들에 대해서도 객체가 존재할 수 있는 후보 영역을 추출한 후 유사도를 측정하는 방법을 제안한다. 제안하는 기법은 평탄 컬러 영역들이 이웃하고 있는 경계부분에서의 Dominant 컬러쌍 정보를 추출하여 특징값으로 사용하였으며, 유사도는 색상을 이용한 Color Correlogram 방법을 사용하였다. 제안하는 Dominant 컬러쌍 특징값은 이동, 회전, 그리고 크기변화에 강건한 특성을 갖는다. 질의 객체 영상에 대해서 DB내에 있는 각각의 영상에 대해 영상 전체를 비교하는 것이 아니라 객체가 존재하는 영역을 추출한 후 유사도를 측정함으로써, 배경 컬러에 의해 영상이 잘못 검출되는 오류가 줄고, 검색 성능이 향상됨을 실험을 통해 확인하였다.

• 식물조직배양학회지
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• 제24권4호
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• pp.197-201
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• 1997

Plant seed oil-bodies or oleosomes ate the repository of the neutral lipid stored in seeds. These organelles in many oilseeds may comprise half of the total cellular volume. Oleosomes are surrounded by a half-unit membrane of phospholipid into which are embedded proteins called oleosins. Oleosins are present at high density on the oil-body surface and after storage proteins comprise the most abundant proteins in oilseeds. Oleosins are specifically targeted and anchored to oil-bodies after co-translation on the ER. It has been shown that the amino-acid sequences responsible for this unique targeting reside primarily in the central hydrophobic tore of the oleosin polypeptide. In addition, a signal-like sequence is found near the junction of the hydrophobic domain and ann N-terminal hydrophilic / amphipathic domain. This "signal" which is uncleaved is also essential for correct targeting. Oil-bodies and their associated oleosins may be recovered by floatation centrifugation of aqueous seed extracts. This simple partitioning step results in a dramatic enrichment for oleosins in the oil-body fraction. In the light of these properties, we reasoned that it would be feasible to create fusion proteins on oil-bodies comprising oleosins and an additional valuable protein of pharmaceutical or industrial interest. It was further postulated that if these proteins were displayed on the outer surface of oil-bodies, it would be possible to release them from the purified oil-bodies using chemical or proteolytic cleavage. This could result in a simple means of recovering high-value protein from seeds at a significant (i.e. commercial) scale. This procedure has been successfully reduced to practice for a wide variety of proteins of therapeutic, industrial and food no. The utillity of the method will be discussed using a blood anticoagulant, hirudin, and industrial enzymes as key examples.

• 대한관절경학회지
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• 제2권2호
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• pp.124-128
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• 1998

From Feb. 1996 to Feb. 1997. among sixty-four patients of anterior cruciate ligament(ACL) reconstruction using multi-stranded hamstring tendon and EndoButton fixation, twenty-five patients of volunteer, 15 men and 10 women, from 16 to 50 years of age(mean 27.6 years) underwent arthroscopic evaluation. Arthroscopic evaluation was routinely performed one year after surgery along with an examination of stability. The purpose of this study was to arthroscopically evaluate the morphological changes that occurred in hamstring tendon autograft one year after ACL reconstruction. Both of the tendon graft and the adjacent fibrous tissues were observed for gross appearance and physical properties with probing and response to passive anterior translation. Biopsy samples were taken from the surrounding fibrous tissue and the tendon graft. Grossly, we found a well-defined ligamentous structure with good tension tested with a probe. A common finding was that the reconstructed ligaments were embedded in a layer of the synovium, and blood vessels could be seen on the anterior surface of the ligament. The biopsy tissue was placed in formalin solution and subjected to histological preparation by hematoxylin and eosin staining method. The hamstring tendon graft appeared histologically normal under light microscopic finding. There were a few vessels located between existing collagen bundles, and the vessels had an orderly pattern. The surrounding fibrous tissue envelope was covered with synovium. We pleased with preliminary findings in our evaluation.