• 제목/요약/키워드: transition region

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Cell Lineage, Self-Renewal, and Epithelial-to-Mesenchymal Transition during Secondary Neurulation

  • Kawachi, Teruaki;Tadokoro, Ryosuke;Takahashi, Yoshiko
    • Journal of Korean Neurosurgical Society
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    • v.64 no.3
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    • pp.367-373
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    • 2021
  • Secondary neurulation (SN) is a critical process to form the neural tube in the posterior region of the body including the tail. SN is distinct from the anteriorly occurring primary neurulation (PN); whereas the PN proceeds by folding an epithelial neural plate, SN precursors arise from a specified epiblast by epithelial-to-mesenchymal transition (EMT), and undergo self-renewal in the tail bud. They finally differentiate into the neural tube through mesenchymal-to-epithelial transition (MET). We here overview recent progresses in the studies of SN with a particular focus on the regulation of cell lineage, self-renewal, and EMT/MET. Cellular mechanisms underlying SN help to understand the functional diversity of the tail in vertebrates.

Condensation-Decondensation Structural Transition of DNA Induced by Reversible Ligand Binding : Effect of Urea on Anomalous Absorbance-Temperature Profile of Spermine-DNA Complex (可逆的 리간드 結合에 의하여 誘發되는 DNA의 응축-풀림 構造變移 : Spermine-DNA 複合體의 異例的 吸光度-溫度 樣相에 미치는 Urea의 影響)

  • Thong-Sung Ko;Chan Yong Lee
    • Journal of the Korean Chemical Society
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    • v.29 no.5
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    • pp.533-538
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    • 1985
  • To investigate the importance of the hydrophobic interaction in the spermine-induced collapse of DNA to a compact structure, the effect of urea on the anomalous absorbance-temperature profile of calf thymus DNA has been investigated. With the increase of the urea concentration, the trough phase of the anomalous absorbance-temperature profile was eliminated eventually. The cooperativity, enthalpy, and the midpoint of the transition to the trough region are more sensitive to urea than those of the Tm-region transition. The present data of the adverse effect of urea, a hydrophobic environmental reagent, on the thermal stabilization of the condensed state of DNA, suggest that hydrophobic interaction may play an important role in the stabilization of the tertiary structure of the collapsed state of DNA.

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Flexural analysis of thermally actuated fiber reinforced shape memory polymer composite

  • Tiwari, Nilesh;Shaikh, A.A.
    • Advances in materials Research
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    • v.8 no.4
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    • pp.337-359
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    • 2019
  • Shape Memory Polymer Composites (SMPC) have gained popularity over the last few decades due to its flexible shape memory behaviour over wide range of strains and temperatures. In this paper, non-linear bending analysis has been carried out for SMPC beam under the application of uniformly distributed transverse load (UDL). Simplified C0 continuity Finite Element Method (FEM) based on Higher Order Shear Deformation Theory (HSDT) has been adopted for flexural analysis of SMPC. The numerical solutions are obtained by iterative Newton Raphson method. Material properties of SMPC with Shape Memory Polymer (SMP) as matrix and carbon fibre as reinforcements, have been calculated by theory of volume averaging. Effect of temperature on SMPC has been evaluated for numerous parameters for instance number of layers, aspect ratio, boundary conditions, volume fraction of carbon fiber and laminate stacking orientation. Moreover, deflection profile over unit length and behavior of stresses across thickness are also presented to elaborate the effect of glass transition temperature (Tg). Present study provides detailed explanation on effect of different parameters on the bending of SMPC beam for large strain over a broad span of temperature from 273-373K, which encompasses glass transition region of SMPC.

Local Structure Refinement of the $BaFe_{1-x}Sn_xO_{3-y}$ System with Fe K-Edge X-Ray Absorption (XANES/EXAFS) Spectroscopy

  • 김민규;곽기섭;로권선;여철현
    • Bulletin of the Korean Chemical Society
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    • v.18 no.7
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    • pp.743-749
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    • 1997
  • Local structure refinement of the BaFe1-xSnxO3-y system (x=0.00-0.50) has been carried out with Fe K-edge x-ray absorpion spectroscopic studies. It is found out that the Fe ions are placed in two different symmetric sites such as tetrahedral and octahedral sites in the compounds by comparison with Fe K-edge x-ray absorption near edge structure (XANES) spectrum of the γ-Fe2O3 compound as a reference. Small absorption peaks of dipole-forbiden transitions appear at a pre-edge region of 7111 eV due to the existence of Fe ions in the tetrahedral and octahedral sites. The peak intensity decreases with the substitution amount of Sn ion. Three different absorption peaks of 1s→4p dipole-allowed transition appear on the energy region between 7123 and 7131 eV. The peaks correspond to 1s→4p main transition of Fe ions in tetrahedral and octahedral sites and 1s→4p transition followed by the shakedown process of ligand to metal charge transfer. The bond distances between Fe ions in the tetrahedral site and nearest neighboring oxygen atom (Fe-4O), and those in octahedral site (Fe-6O) are determined with the extended x-ray absorption fine structure (EXAFS) analysis. Two different interatomic distances increase with the substitution amount of Sn ion and also the bond lengths of Fe-4O are shorter than those of Fe-6O in all compounds.

Unsteady Flow Analysis through the Subcritical-Supercritical Transition Region (개수로에서의 상류-사류 천이영역에 대한 부정류 해석)

  • 한건연;박재홍;이종태
    • Water for future
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    • v.27 no.2
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    • pp.85-96
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    • 1994
  • Numerical instability of Preissmann scheme is studied for unsteady flow analysis in a natural river. The solution strategies to overcome the instability problems are presented in this paper. The main causes of numerical instability of Preissmann scheme are transition flow, abrupt change in cross section, in-appropriate roughness coefficients, time step and distance step, rapidly rising hydrograph, dry bed and so on. Transition flow model is proposed for the analysis of the transition flow which changes from subcritical to supercritical or conversely. The subcritical and supercritical reaches are groped in the channel, then appropriate boundary conditions are introduced for each reach. The transition flow analysis produces stable solutions in calculating through the various transition conditions. Verification with an actual river system is necessary in the future.

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Effect of Temperature on the Fracture Toughness of A516 Gr70 Steel

  • Seok, Chang-Sung
    • Journal of Mechanical Science and Technology
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    • v.14 no.1
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    • pp.11-18
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    • 2000
  • Fracture toughness JIC and KIC tests were performed on A516 Gr70 carbon steel plate at the temperature ranging from -$160^{\circ}C$ to $600^{\circ}C$, and test results were analyzed according to ASTM E 813 and ASTM E 399. Unloading compliance J-integral tests were performed on 1TCT specimens. The relation between the $J_{IC}$ value and the test temperature was obtained. It was concluded that the temperature ranging from $-15^{\circ}C$ to $600^{\circ}C$ is the upper shelf region of ductile-brittle transition temperature, and in this temperature range, fracture toughness $J_{IC}$ values decreased with increasing temperature. The ductile brittle transition temperature of the material may be around $-30^{\circ}C$. In the region near $-30^{\circ}C$, the tendency of $J_{IC}$ to decrease with decreasing temperature was significant.

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An Experimental Study of The Effects of The Mixing Vane on Air-water Mixed Flow

  • Kim, Soo-Hyung;Baek, Won-Pil;Chang, Soon-Heung
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05b
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    • pp.331-336
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    • 1996
  • The effects of a mixing vane on air-water mixed flow have been experimentally studied in this work, to investigate the basic mechanisms that the mixing vane affects critical heat flux (CHF). Experiment was performed for various flow rates focusing on bubbly flow and annular flow patterns. Acrylic tube (1.7m long, 11 mm I.D.) and the split vane type mixing vane were used, and ring-type conductance probes were used to measure the liquid film thickness in annular flow. Experimental results show that, (a) bubbly-to slug flow transition and churn-to-annular flow transition occur respectively near the mixing vane compared to the tests without mixing vane, (b) in bubbly flow region, the mixing vane breaks the bubbles into smaller ones and forwards bubbles to the center region of the tube by the centrifugal force, (c) the liquid film thickness in annular flow is decreased near the mixing vane for mass fluxes.

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Observations of the CH3OH 42-51 E Line Toward the Sgr B2 Region

  • Minh, Young-Chol;Kim, Sang-Joon
    • Journal of Astronomy and Space Sciences
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    • v.28 no.1
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    • pp.13-16
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    • 2011
  • The $CH_3OH$ $4_2-5_1$ E transition was observed toward the Sgr B2 region, including the Principal Cloud and its surroundings. This methanol transition shows an extended emission along the 2'N cloud, which is believed to be colliding with the Principal Cloud and may trigger the massive star formation in this cloud. This extended methanol emission may also suggest that the 2'N cloud is under shocks. We derive total methanol column density $N(CH_3OH)\;=\;2.9{\pm}0.3{\times}10^{14}\;cm^{-2}$ toward the peak position of the extended emission. The fractional abundance of methanol is about 10.9, relative to the estimated total $H_2$ abundance, which is similar to the methanol abundances in quiet gas phase.

정전위법에 의한 Alloy 600의 입계응력부식균열 거동 연구

  • 맹완영;강영환;일본명
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05c
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    • pp.111-116
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    • 1996
  • IGSCC(Intergranular stress corrosion cracking) behaviors of Alloy 600 were studied by the electrchemical ten methods of controlling specimens electrode potentials in the active-passive transition region of anodic polarization curve. Anodic polarization and static potential tests of stressed C-ring type MA Alloy 600 were carried out in 10% NaOH at 300 $^{\circ}C$ for 7days. It was confirmed that IGSCC of Alloy 600 was accellerated by maintaining the specimen potential in the susceptible active-passive transition region of anodic polarization curve. An intergranular crack was initiated on the surface area of C-ring specimens where protective oxide layer was broken down. And the depth of the crack growth was about 100 ${\mu}$m during the testing periods.

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Visualization of Turbulent Flow around a Sphere (구 주위 난류유동에 관한 가시화 연구)

  • Jang, Young-Il;Lee, Sang-Joon
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.401-402
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    • 2006
  • The turbulent flow around a sphere was investigated using two experimental techniques: smoke-wire flow visualization in wind tunnel at Re=5300, 11000 and PIV measurements in a circulating water channel. The smoke-wire visualization shows flow separation points near an azimuthal angle of $90^{\circ}$, recirculating flow, transition from laminar to turbulent shear layer, evolving vortex roll-up and fully turbulent eddies in the sphere wake. The mean velocity field measured using a PIV technique in x-y center plane demonstrates the detailed near-wake structure such as nearly symmetric recirculation region, two toroidal vortices, laminar separation, transition and turbulent eddies. The PIV measurements of turbulent wake in y-z planes show that a recirculating vortex pair dominates the near-wake region.

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