• Proceedings of the Botanical Society of Korea Conference
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• 1987.07a
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• pp.51-62
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• 1987

Higher plant transformation vector systems are mainly developed based on the natural biosystems which infecting higher plants. Two major groups attracting much of the research are Cauliflower mosaic virus and Agrobacterium tumefaciens. Cauliflower mosaic virus has a double stranded genome, and a portion of the genome can be substituted for a foreign DNA segment without loosing the ability of infection. A. tumefaciens carries a large plasmid. Ti plasmid whose portion can be substitute and trasferred into the plant chromosome.

• YAKHAK HOEJI
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• v.37 no.6
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• pp.555-560
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• 1993

Methyl 3-[(phenylsulfonyl)methyl]-1, 4, 8-trimethoxy-2-naphthoate(7) preparad by 3 steps was condensed with 5-ethyl-2-cyclohexen-1-one(8) to afford the teracyclic aromatic ring system compound 10, which was stepwise converted into the precursor of 11-Deoxy-$\beta$-rhodomycinone by means of various functional groups transformation.

• The Journal of Internal Korean Medicine
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• v.19 no.1
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• pp.221-246
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• 1998

The aim of this experimental study was to evaluate the anti-tumor effects of Chungsimbohyeltang through investigation about viability of tumor cell by MTT assay, survival period of mice transplanted with L-1210 cells, growth inhibition on the tumor cell, body weight variation in mice transplanted with sarcoma-180 cells and its immunomodulatory effects through the investigation on delayed type hyper-sensitivity, the hemagglutinin and hemolysin titers for humoral immune response, the appearance of rosette forming cells for cell-mediated immune response, the natural killer cell activity, the transformation of lymphocyte, the productivity of Interleukin-2 and phagocytic index K was performed in immune-depressed ICR mice induced by methotrexate treatments. The results were as follows ; 1. $IC_{50}$ of Chungsimbohyeltang treated group was 5.85mg/ml in SNU-C4 cell, 1.38mg/ml in SNU-396 cell, 0.21mg/ml in SNU-1 cell, so it had low anti-tumor activity. 2. The both groups of Chungsimbohyeltang extract 10mg/kg and Chungsimbohyeltang extract 20mg/kg had no toxicity and the group of Chungsimbohyeltang 20mg/kg which was shown 120% in ILS had the effect of life prolongation in mice transplanted with L-1210 cells. 3. In the growth inhibition on the tumor cells, only the group of Chungsimbohyeltang extract 20mg/kg was noted and in the weight variation in mice transplanted with sarcoma-180 cells, both groups of Chungsimbohyeltang extract had a significant effect. 4. In the delayed type hypersensitivity and appearance of rosette forming cells, both groups of Chungsimbohyeltang extract didn't have any significant effect. 5. The hemagglutinin titers was slightly increased with no significance, and the hemolysin titers was significantly increased in the only group of Chungsimbohyeltang extract 20mg/kg. 6. The natural killer cell activity of the Chungsimbohyeltang extract groups was significantly increased in the ratio of 100:1 of effector and target cells, but it was not significantly increased in the ratio of 50:1, 10:1. 7. The transformation of lymphocyte and the productivity of Interleukin-2 were increased significantly and in dose-dependent manner in both group of Chungsimbohyeltang extract. 8. The phagocytic effect of macropage was significantly increased in both groups of Chungsimbohyeltang extract. Considering the results above, we could conclude that Chungsimbohyeltang have an indirect anti-tumor effect through the modulation of immunme response, although it had not toxicity on the tumor cell it self.

• Korean Journal of Human Ecology
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• v.17 no.6
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• pp.1225-1236
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• 2008

The purpose of this study is to determine the effect of aromatherapy, showing how the composition handling of aromatherapy and abdominal massage treatment reaches body ingredient transformation. The subjects for this research were total 18 middle-aged females in Seoul; aroma massage group of 7 females, aroma inhalation and water bathe group of 5 females, abdominal massage group of 6 females by jojoba oil without any medical effect. This clinic trial was held from July 1, 2008 to Aug.14, 2008. I held this clinic trial under the same condition after and before this clinic. A standard tape and OLYMPIA 3.5 of S hospital were used at the body measuring for subjects after and before clinic trials. I got Average and standard deviation by data analysis by SPSS Win. Ver.14.0. I did paired t-test for the comparison of before and after, and repeated measure ANOVA for between two groups or among three groups'. The verification was held Duncan Test. The results of this study were as follows: 1. Body mass quotient (F=2.86, p= .063) and Body region (F=1.34, p= .279) among three groups showed no meaningful difference, but weight meaningful difference and aroma massage group showed the greatest difference of body measure change quantity. 2. In change quantity of abdomen girth, Waist circumference and WHR, abdomen girth (F=4.56, p= .012) and Waist circumference (F=4.37, p= .031) showed a meaningful statistical difference. The result of subsequent inspection showed that there was a meaningful difference among three groups and aroma massage group was best. 3. In Cell quantity, Body region quantity and Muscle volume, Body region quantity (F=2.76, p= .182) and Muscle volume (F=3.12, p= .054) showed no difference, but Cell quantity (F=3.79, p= .040) showed a meaningful difference. In the comparison of three groups there was no difference, but aromatherapy group showed more change quantity than any other group. According to the result of this study, the composition handling of aromatherapy and body massage was effective in the decrease of Abdominal fatness and Waist circumference, Weight and the increase of Cell quantity. so I suggest that woman use this therapy in the program of obesity management for her health improvement.

• Journal of The Korean Association For Science Education
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• v.29 no.8
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• pp.848-860
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• 2009

This study examined the characteristics of scientists' writing on the laboratory reports written in the authentic open inquiry, and explored the possibility that the class discussion after the inquiries could influence the laboratory report writing. The samples were 131 10th graders in a science high school in Seoul. The control group (n=45) practiced traditional school science inquiries, the experimental group 1 (n=43) practiced the authentic open inquiries, and the experimental group 2 (n=43) practiced the authentic open inquiries and the class discussion after the laboratory activities. Their laboratory reports were analyzed into three parts - prediction (prediction with background and apposite description), data analysis (data transformation and critical analysis), and conclusion (objective description based on evidence). The frequency of the characteristics of scientist's writing in the experimental group was higher than the control group. Particularly, the differences of the prediction with background (p<.01) and the critical analysis of data (p<.05) were statistically significant. However, the frequency of writing the conclusion based on evidence was very low in all of the three groups. The result from comparing descriptions of reports showed that the writing prediction in experimental groups were more elaborate, and the data transformation in experimental groups were more correct, and the evaluation to data in experimental groups were more critical than the control group. And the descriptions of the critical evaluation to data and the finding flaw in methods were found in experimental groups 2, indicating that the class discussion can stimulate students' scientific thinking.

• Bulletin of the Korean Chemical Society
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• v.32 no.2
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• pp.664-672
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• 2011

A series of hydrophilic chromophores was synthesized through introduction of dendritic sulfonate anions using click chemistry. A dendron structure bearing several sulfonate groups enhances hydrophilicity of attached chromophores. A click triazole formation connects chromophores with hydrophilic groups. A neutral trichloroethyl sulfonate has versatile features such as easy introduction, chemical endurance for isolation or storage, and convenient transformation to a hydrophilic anion. Zinc and OH mediated cleavage of trichloroethyl group from the neutral sulfonate undergoes to generate a water-soluble sulfonate anion. The solubility was examined with different counter cations and in different pH media and thus increased with the number of attached sulfonate ion. Two hydrophilic chromophores of stilbene-derived and azobenzene-derived dipolar structures exhibit clear negative and positive solvatochromism in protic solvents, respectively.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.27 no.3
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• pp.59-65
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• 2004

This paper explores an image segmentation and representation method using Vector Quantization(VQ) on color and texture for content-based image retrieval system. The basic idea is a transformation from the raw pixel data to a small set of image regions which are coherent in color and texture space. These schemes are used for object-based image retrieval. Features for image retrieval are three color features from HSV color model and five texture features from Gray-level co-occurrence matrices. Once the feature extraction scheme is performed in the image, 8-dimensional feature vectors represent each pixel in the image. VQ algorithm is used to cluster each pixel data into groups. A representative feature table based on the dominant groups is obtained and used to retrieve similar images according to object within the image. The proposed method can retrieve similar images even in the case that the objects are translated, scaled, and rotated.

• Journal of the Optical Society of Korea
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• v.13 no.1
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• pp.131-138
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• 2009

The similarity between two groups of displaying methods is demonstrated in two ways, analytically and experimentally. A variety of layouts of the integral photography and display devices based on the point light source model is classified and analyzed in terms of projections and common/separate image planes. In particularly, the transformation matrix is found. Simulation experiments based on the image processing were performed. The layouts, analytical formulas, and experimental results show the similarity of both groups for several layouts.

• Journal of Acupuncture Research
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• v.17 no.4
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• pp.28-40
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• 2000

Objectives : This study was purposed to investigate the effect of honey bee venom aqua-acupuncture on decreased immune response by its production from Korea, North America and China. Methods : ICR-mouse was exposed with four minute sublethal 60Co- $\gamma$ -ray irradiation onto the body and got a series of each country's 0.1 ml honey bee venom aqua-acupuncture to Choksamni(ST36) every other day for three times. Thereafter the numbers of WBC, delayed type hypersensitivity, hemagglutinin titers, hemolysin titers, quantitation of T-cell and B-cell, lymphocyte transformation, natural killer cell activity, interleukin-2 productivity and interferon productivity were measured. Results : The numbers of WBC, delayed type hypersensitivity, hemagglutinin titers, hemolysin titers, quantitation of T-cell and B-cell and lymphocyte transformation were increased respectively with statistical significance in Korean, North American and Chinese honey bee venom aqua-acupuncture groups as compared with the control group. The natural killer cell activity was increased with statistical significance in Korean honey bee venom aqua-acupuncture group, and Interleukin-2 productivity and interferon productivity were not shown any statistical significance in all experimental groups as compared with the control group. Conclusions : According to the results, honey bee venom aqua-acupuncture has significant effect on decreased immune response, and Korean bee venom can be substituted for North American and Chinese one.

• The Journal of Advanced Prosthodontics
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• v.12 no.5
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• pp.265-272
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• 2020

PURPOSE. The aims of this study were to investigate mechanical properties and hydrothermal degradation behaviour of the cubic-containing translucent yttrium oxide stabilized tetragonal zirconia polycrystal (Y-TZP). MATERIALS AND METHODS. Four groups of Y-TZP (T, ST, XT, and P), containing different amount of cubic crystal, were examined. Specimens were aged by autoclaving at 122℃ under 2 bar pressure for 8 h. Phase transformation was analyzed using X-ray diffraction (XRD) to measure phase transformation (t→m). Kruskal-Wallis test was used to determine the difference. Surface hardness, biaxial flexural strength, and fracture toughness in values among the experimental groups and verified with Wilcoxon matched pairs test for hardness values and Mann Whitney U for flexural strength and fracture toughness. RESULTS. XRD analysis showed no monoclinic phase in XT and P after aging. Only Group T showed statistically significant decreases in hardness after aging. Hydrothermal aging showed a significant decrease in flexural strength and fracture toughness in group T and ST, while group XT and P showed no effect of aging on fractural strength and fracture toughness with P<.05. CONCLUSION. Hydrothermal aging caused reduction in mechanical properties such as surface hardness, biaxial flexural strength, and fracture toughness of Y-TZP zirconia. However, cubic-containing zirconia (more than 30% by volume of cubic crystal) was assumed to have high resistance to hydrothermal degradation. Clinical significance: Cubic-containing zirconia could withstand the intraoral aging condition. It could be suggested to use as a material for fabrication of esthetic dental restoration.