• Journal of Nutrition and Health
• /
• v.29 no.1
• /
• pp.41-49
• /
• 1996

Bacterial transformation of bile acids is possibly involved in colorectal carcinogenesis. n several epidemiological studies, the fecal bile acid dietary fiber are related to the indicence of colonic cancer. This study investigated the influence of age, dietary fiber intake on fecal bile acid profiles in healthy subject. The dietary fiber were assessed by mean of 24 hour dietary recall method, the subjects consist of 238 members aged 20 to 64 years old and feces are collected from the subjects. Fecal bile acids and neutral sterols were analyzed by gas chromatography. Mean dily crude fiber intake level was 7.7$\pm$1.4g(dietary fiber : 16.7$\pm$3.5g), dietary fiber intake range being 6.5-36.8g. The dietary fiber intake in elederly subject was significantly lower than in the other younger groups. Dietary fiber intakes was negatively correlated with the total bil acid concentation in feces. Probably, a decrease in dietary fiber intake results in higher fecal bile acid concentrations. The secondary bile acid concentration is related to the colon cancer, deoxycholic acid and lithocholic acid were significantly higher in elderly subjects. Concentration of fecal total bile acid, deoxycholic acid, coprostanol, coprostanone were higher in low dietary fiber intake group. These results suggest that the risk factor for colon cancer might be reduced, when dietary fibers are consummed more.

• Environmental Mutagens and Carcinogens
• /
• v.22 no.4
• /
• pp.312-318
• /
• 2002

Dioxin represents a group of halogenated aromatic hydrocarbons of which 2,3,7,8-tetrachlorod-ibenzo-p-dioxin (TCDD) is well known for its extremely toxic properties as well as ubiquitous presence in our environment and ecosystems. In order to better assess the carcinogenic mechanism of dioxin, we should utilize the reliable biomarkers that can precisely and correctly reflect multi-stage carcinogenesis. When MCF10A cells were exposed to TCDD (10 nM), expression of both CYP1A1 and CYP1B1 was induced in a time-related manner. The expression as well as activity of ornithine decarboxylase was transiently induced by TCDD treatment. In contrast, the induction of COX-2 that is implicated in carcinogenesis as well as inflammation, was not induced by TCDD. In another study, gap-junctional intercellular communication (GJIC) was attenuated by TCDD treatment as revealed by the dye-transfer assay. Based on these findings, TCDD has both tumor initiating and promoting potential in human breast epithelial cells in culture. Also, treatment of MCF10A cells with the carcinogen 7,12-dimethylbenz[a]anthracene plus TCDD resulted in malignant cell transformation as revealed by increased anchorage-independent growth of exposed cells. Additional studies may be necessary to assess the effects of TCDD on multi-stage carcinogenesis in vivo.

• Journal of the Korea society of information convergence
• /
• v.1 no.1
• /
• pp.17-24
• /
• 2008

Video camera play very important roles for preventing many kinds of crimes and resolving those crime affairs. But in the case of recording image of a specific person far from the CCTV, the original image needs to be enlarged and recovered in order to identify the person more obviously. Interpolation is usually used for the enlargement and recovery of the image in this case. However, it has a certain limitation. As the magnification of enlargement is getting bigger, the quality of the original image can be worse. This paper uses FOP(Facial Definition Parameter) proposed by the MPEG-4 SNHC FBA group and introduces a new algorithm that uses face outline information of the original image based on the FOP, which makes it possible to recover better than the known methods until now.

• Journal of the Korean Chemical Society
• /
• v.45 no.6
• /
• pp.538-545
• /
• 2001

The ratio of regioisomers in nitration of biphenyl derivatives containing electron-with-drawing group was examined. The ratio of isomers was determined efficiently by quantitative analysis of $^1$H NMR spectrum of product mixture based on $^1$H NMR spectrum of each isomer. Some isomers were isolated after chemical transformation, nitro to amine or carboxylic acid to its ethyl ester, because direct separation was very difficult. To improve the regiselectivity, representative several reaction conditions were tried and the NMR method was applied to determine regioselectivity in nitration of biphenyl derivatives. It was observed that the regioselectivity depend on not only reaction conditions but also position and kind of substituents.

• Clean Technology
• /
• v.11 no.1
• /
• pp.29-39
• /
• 2005

Polychlorinated biphenyls, (PCBs) are a group of highly toxic chlorinated industrial chemicals used as dielectrics, coolants and lubricants in electrical transformers. This article reviewed the state-of-the-art on technologies for decomposition of Polychlorinated biphenyls (PCBs), one of the persistent organic materials (POPs). The purpose of this study was to evaluate the feasibility of decontaminating PCBs contaminated pollutants using treatment technologies such as chemical dechlorination, photodegradation and biological transformation.

• Fashion & Textile Research Journal
• /
• v.10 no.2
• /
• pp.236-241
• /
• 2008

Hair manicure is usually and widely operated in the area of hair-dyeing by the reason that acidic hair color is less damaged and more stable than other chemical color treatment. However, there is no an in-depth study to prove them. This study purposes to provide basic resources for effectively using products of hair manicure by experiments on Physical Properties of Hair. Hair of one healthy woman in mid-20's, Level 4, was sampled for experiments. For the tests, hair samples were classified by the frequency of hair manicure treatment The control group(a), once treatment(b), twice(c), three times(d), four times(e) and five times(f). The results were measured with Scanning Electron Microscopy(SEM) and Tensile Strength and Elongation test. The lower Values of Tensile Strength according to repeated hair manicure treatment. Elongation is not affected by the frequency of hair manicure treatment. There was no remarkable change of hair surface in once(b) and twice(c) treatment. The change of hair surface which was able to judge by cuticle layers looseness, tunics and the transformation of cuticle cell were observed in the hair samples operating more than three times(d) of hair manicure treatment.

• The Research Journal of the Costume Culture
• /
• v.16 no.6
• /
• pp.1142-1155
• /
• 2008

The purpose of this study is to analyze the effects of playful aspects through the research into characteristics and playful expressional tendency that are expressed in the contemporary fashion illustration. This study covered from 1995, the beginning point of play trend spreading, to 2006 and the fashion magazines, illustrator's collections, and about 1800 pieces of work which have been revealed on the internet web site were collected. At the next stage, 443 pieces of work were selected by researcher for a questionnaire. As a result of the questionnaire, ultimately frequency was more than n=5, so it examined playful expression characteristics, the methods and the effects of the modern fashion illustration based on 335 pieces of work(75.6% of total sample) which were selected by the majority of expert group. It showed the biggest part of playful expression tendency in the modern fashion illustration was 'simplification', and second one was 'exaggeration'. 'Immature expression' and 'fantastic expression' which are included in kidult expression were next. Hopefully, this study would be helpful for creative expression of the fashion illustration which is fit for spreading play trend in modern society.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2012.10a
• /
• pp.874-877
• /
• 2012

This paper proposes the new method based on contour following method with directional angle to segment the cell into the nuclei. The object image was the Thyroid Gland cell image that was diagnosed as normal and abnormal(two types of abnormal : follicular neoplastic cell, and papillary neoplastic cell), respectively. The nuclei were successfully diagnosed as normal and abnormal. this paper, improved method of digital image analysis required in basic medical science for diagnosis of cells was proposed. The object image was the Thyroid Gland cell image with difference of chromatin patterns. To segment the cell nucleus from background, the region segmentation algorithm by edge tracing was proposed. And feature parameter was obtained from discrete Fourier transformation of image. After construct a feature sample group of each cells, experiment of discrimination was executed with any verification cells. As a result of experiment using features proposed in this paper, get a better segmentation rate(70-90%) than previously reported papers, and this method give shape to get objectivity and fixed quantity in diagnosis of cells. The methods described in this paper be used immediately for discrimination of neoplastic cells.

• Journal of the Korean Operations Research and Management Science Society
• /
• v.20 no.2
• /
• pp.39-60
• /
• 1995

In this paper, an integration of stochastic dynamic programming (SDP), integer goal programming (IGP) and analytic hierarchy process (AHP) is proposed to handle multiobjective-multicriteria sequential decision making problems under uncertainty inherent in R & D investment planning. SDP has its capability to handle problems which are sequential and stochastic. In the SDP model, the probabilities of the funding levels in any time period are generated using a subjective model which employs functional relationships among interrelated parameters, scenarios of future budget availability and subjective inputs elicited from a group of decision makers. The SDP model primarily yields an optimal investment planning policy considering the possibility that actual funding received may be less than anticipated one and thus the projects being selected under the anticipated budget would be interrupted. IGP is used to handle the multiobjective issues such as tradoff between economic benefit and technology accumulation level. Other managerial concerns related to the determination of the optimal project portifolio within each stage of the SDP model. including project selection, project scheduling and annual budget allocation are also determined by the IGP. AHP is proposed for generating scenario-based transformation probabilities under budgetary uncertainty and for quantifying the environmental risk to be considered.

• Journal of the Korean Chemical Society
• /
• v.34 no.6
• /
• pp.641-645
• /
• 1990

Ethanolic tetracarbonylhydridoferrate, HFe(CO)$_4^-$, combined with aqueous succinaldehyde is very efficient for the selective transformation of an amino group into a pyrrolidine ring. Phenylendiamines react with aqueous succinaldehyde in the presence of HFe(CO)$_4^-$, at room temperature under atmospheric pressure of carbon monoxide to give the corresponding pyrrolidines in moderate yields. In these reactions, the molar ratio of 1.0:1.0:1.0 of the ferrate-succinaldehydephenylenediamine system gave one pyrrolidine ring, and the case of 1.0:2.0:1.0 gave two pyrrolidine rings, selectively.