• 제목/요약/키워드: transformation etc

검색결과 295건 처리시간 0.024초

Flipped Learning: Strategies and Technologies in Higher Education

  • Miziuk, Viktoriia;Berdo, Rimma;Derkach, Larysa;Kanibolotska, Olha;Stadnii, Alla
    • International Journal of Computer Science & Network Security
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    • 제21권7호
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    • pp.63-69
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    • 2021
  • Flipped learning is necessary for modern education but quite difficult to implement. In pedagogical science, the question remains to what extent the practical work of the teacher in combination with the technologies of flipped learning will improve the quality of higher education. The aim of this article is to study the effectiveness and feasibility of using flipped learning technologies, assessing their perception by students (advantages and problems), identified an algorithm for introducing flipped learning technology in higher education institutions. Research methods. The main method is an experiment. An evaluation of the effectiveness of the study was conducted using a questionnaire and observation method. Statistical methods were used to evaluate the results of the experiment. The research hypothesis is that flipped learning allows the teacher to spend more time on an individual approach, to understand the real needs of students, and provide effective feedback, thereby improving the quality of learning and motivation of students, especially while studying complex material. The results of the study are to prove the effectiveness of the technology of flipped education in the study of complex disciplines, courses, topics. The use of flipped learning strategies improves the self-regulation of the educational process, group work skills, improves students' ability to learn, overcome difficulties. The technology of flipped learning in the presence of modern technical means and constant work on improving the level of digital literacy is an effective means for students to master complex topics and problematic issues that require additional consideration and discussion. The perspective of further research is the consideration of integrated approaches to the application of flipped learning technologies to the principles of STEAM-education, multilingual and multicultural programs, etc. It is also worth continuing to develop a set of methods aimed at enhancing the student's learning activities, the formation of group work skills, direct participation in creating the foundations of higher education.

Flow of MHD Powell-Eyring nanofluid: Heat absorption and Cattaneo-Christov heat flux model

  • Sharif, Humaira;Khadimallah, Mohamed A.;Naeem, Muhammad Nawaz;Hussain, Muzamal;Hussain, Sajjad;Tounsi, Abdelouahed
    • Advances in nano research
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    • 제10권3호
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    • pp.221-234
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    • 2021
  • During the previous few years, phenomenon of bioconvection along with the use of nanoparticles showed large number of applications in technological and industrial field. This paper analyzed the bioconvection phenomenon in magnetohydrodynamic boundary layer flow of a Powell-Eyring nanoliquid past a stretchable cylinder with Cattaneo-Christov heat flux. In addition, the impacts of chemical reaction and heat generation/absorption parameter are considered. By the use of appropriate transformation, the governing PDEs (nonlinear) have been transformed and formulated into nonlinear ODEs. The resulting nonlinear ODEs subjected to relevant boundary conditions are solved analytically through homotopy analysis method which is programmed in Mathematica software. Graphical and numerical results versus physical quantities like velocity, temperature, concentration and motile microorganism are investigated under the impact of physical parameters. It is noted that velocity profile enhances as the curvature parameter A and Eyring-Powell fluid parameter M increases but a decline manner for large values of buoyancy ratio parameter Nr and bio-convection Rayleigh number Rb. In the presence of Prandtl number Pr, Eyring-Powell fluid parameter M and heat absorption parameter ��, temperature profile decreases. Nano particle concentration profile increases for increasing values of magnetic parameter Ha and thermophoresis parameter Nt. The motile density profile has revealed a decrement pattern for higher values of bio-convection Lewis number Lb and bio-convection peclet number Pe. This study may find uses in bio-nano coolant systems, advance nanomechanical bio-convection energy conversion equipment's, etc.

위험도 기반 도로 모니터링 및 관리 시스템 구축 방안 (A Methodology on System Implementation for Road Monitoring and Management Based on Automated Driving Hazard Levels)

  • 김규옥;이상수;조선아
    • 한국ITS학회 논문지
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    • 제21권6호
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    • pp.299-310
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    • 2022
  • 자율주행시스템은 자율주행 센서, 판단 및 제어 알고리즘 등을 기반으로 스스로 자율주행할 수 있는 기능을 갖추고 있다. 자율주행의 안전성은 도로 네트워크의 운영 상태와 관련성이 높고 도로 인프라와의 협력이 필요하다. 자율주행의 안전한 운행을 위해서는 지속적으로 도로와 교통 조건이 적합한지를 모니터링 할 필요가 있다. 본 연구는 자율주행시스템의 ODD (Operational Design Domain) 특성에 따라 선정된 모니터링 항목을 관리할 수 있는 체계를 구축하기 위한 노드와 링크 체계를 제시하였다. 확장성을 고려하여 기존의 ITS 표준 노드링크 체계를 기반으로 하였으며, 모니터링 대상을 노드와 링크로 표출하는 방안을 제시하였다. 위험도를 5단계로 구분하고 관리하는 방안과 최적경로 탐색 및 통제 시 노드와 링크의 정보를 활용하는 방안을 제시하였다. 세종시를 대상으로 제시된 노드와 링크체계를 기반으로 한 시스템구축 사례를 소개하였다.

Molding the East Asian Dragons: The Creation and Transformation of Various Ecological and Political Discourses

  • NGUYEN Ngoc Tho;PHAN Thi Thu Hien
    • 대순사상과 동아시아종교
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    • 제2권2호
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    • pp.73-99
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    • 2023
  • The dragon is a special imaginary figure created by the people of East Asia. Its archetypes appeared primarily as totemic symbols of different tribes and groups in the region. The formation of early dynasties probably generated the molding of the dragon symbol. Dragon symbols carried deep imprints of nature. They concealed alternative messages of how ancient people at different locations dealt with or interacted with nature. Under pressure to standardize in the medieval and late imperial periods, the popular dragon had to transform physically and ideologically. It became imposed, unified, and framed, conveying ideas of caste classification and power, and losing itsecological implications. The dragon transitioned from a semi-ecological domain into a total social caste system. However, many people considered the "standardized" dragon as the symbol of the oppressor. Because of continuous orthopraxy and calls for imperial reverence, especially under orthopractic agenda and the surveillance of local elites, the popularized dragon was imbued within local artworks or hidden under the sanctity of Buddhas or popular gods in order to survive. Through disguise, the popular dragon partially maintained its ecological narratives. When the imperial dynasties ended in East Asia (1910 in Korea, 1911 in China, 1945 in Vietnam), the dragon was dramatically decentralized. However, trends of re-standardization and re-centralization have emerged recently in China, as the country rises in the global arena. In this newly-emerging "re-orthopraxy", the dragon has been superimposed with a more externally political discourse ("soft power" in international relations) rather than the old-style standardization for internal centralization in the late imperial period. In the contemporary world, science and technology have advanced humanity's ability to improve the world; however, it seems that people have abused science and technology to control nature, consequently damaging the environment (pollution, global warming, etc.). The dragon symbol needs to be re-defined, "re-molded", re-evaluated and reinterpreted accordingly, especially under the newly-emerging lens-the New Confucian "anthropocosmic" view.

곡면을 가진 외팔보형 PVDF 에너지 하베스터의 와류유기진동으로 인한 에너지 수확 특성 (Energy harvesting characteristics on curvature based PVDF cantilever energy harvester due to vortex induced vibration)

  • 송우진;이종길
    • 한국음향학회지
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    • 제43권2호
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    • pp.168-177
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    • 2024
  • 수중 압전 에너지 하베스터(Piezoelectric Energy Harvester, PEH) 설계시 곡률변화를 통해 외팔보형 전체의 와류유기진동(Vortex Induced Vibration, VIV)을 생성시키고, VIV의 생성으로 곡면형 외팔보 PEH에 진동 변위가 증가한다는 것은 실제 전력을 증대 시키는 데 중요한 요소이다. 해석 모델인 곡면형 PEH의 재질은 Polyvinyline Di-Floride(PVDF) 압전 필름으로서 곡률이 다양한 50 mm, 130 mm, 210 mm 모델에 유속은 0.1 m/s ~ 0.50 m/s로 정하여 VIV에 의한 PEH의 스트레인 에너지 변화를 관찰하였다. 곡률 반경이 작을수록 큰 폭의 VIV가 나타났고, 유속이 증가할수록 VIV가 많이 나타났다. 작은 곡률로 인한 급격한 형상변환이 VIV의 생성에 효과적이었고 스트레인 에너지, 정규화 발생 전압, 평균 전력 등은 곡률이 증가할수록 감소하였다. PEH 자체의 전력량을 증대시키기 위해 급한경사의 곡률 개선뿐만 아니라 곡률형 PEH의 개수가 늘어남에 따라 평균 전력도 상승할 것으로 사료된다.

설명가능한 의사결정을 위한 마이닝 기술 (Research on Mining Technology for Explainable Decision Making)

  • 정경용
    • 융합신호처리학회논문지
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    • 제24권4호
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    • pp.186-191
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    • 2023
  • 데이터 처리 기술은 의사결정을 위해 중요한 역할을 하며, 데이터 결측값 및 이상값 처리, 예측, 추천 모델 등이 포함 된다. 이는 모든 과정과 결과의 타당성, 신뢰성, 정확성에 대한 명확한 설명이 필요하다. 또한 의사결정트리, 추론 등을 이용한 설명가능한 모델을 통해 데이터의 문제를 해결하고, 다양한 유형의 학습을 고려하여 모델 경량화를 진행할 필요가 있다. 육하원칙을 적용한 다중 계층 마이닝 분류 방법은 데이터 전처리 후 트랜잭션에서 빈번하게 발생하는 변수와 속성 간의 다차원 관계를 발견하는 방법이다. 이는 트랜잭션에서 마이닝을 이용하여 유의미한 관계를 발견하고, 회귀분석을 통해 데이터를 모델링 하는 방법을 설명한다. 이에따라 확장 가능한 모델과 로지스틱 회귀모델을 개발하고, 데이터 정제, 관련성 분석, 데이터 변환, 데이터 증강을 통해 클래스 레이블을 생성하여 설명가능한 의사결정을 위한 미이닝 기술을 제안한다.

일출일몰 데이터를 이용한 인간 중심 조명 구현에 관한 연구 (A Study on Implementation of Human Centric Lighting Using Sunrise and Sunset Data)

  • 장두원;김충혁;조규원
    • 한국전기전자재료학회논문지
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    • 제37권5호
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    • pp.486-493
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    • 2024
  • Lighting has been used for a long time as a medium to convey brightness from darkness, and through incandescent lamps and fluorescent lamps, LED light sources have now become the standard in the lighting industry. Recently, the lighting equipment industry has been undergoing rapid digital transformation, starting with smart lighting, and is evolving into smart lighting customized for individuals and spaces through the development of IoT technology, cloud-based services, and data analysis. However, the blue light emitted from digital devices (computers, smartphones, tablets, etc.) or LED lights stimulates the melanopsin in the optic ganglion cells in the retina of the eye, which in turn stimulates the secretion of melatonin through the pineal gland, which regulates the secretion of melatonin. This can reduce sleep quality or disrupt biological rhythms. This interaction between blue light and melatonin has such a significant impact on human sleep patterns and overall health that it is essential to reduce exposure to blue light, especially in the evening. Human-centered lighting refers to lighting that takes into account the effects of light on the physical and mental areas, such as human activity and awakening, improvement of sleep quality, and health management. Many research institutes study the effects in the visible area and the non-visible area. By studying the impact, it is expected to improve the quality of human life. In this study, we plan to study ways to implement human-centered lighting by collecting sunrise and sunset data and linking commercialized LED packages and control devices with open-source hardware.

"삼국사기(三國史記)"에 기록된 의약내용(醫藥內容) 분석 (Study on Medical Records In ${\ulcorner}$the Historical Records of the Three Kingdoms${\lrcorner}$)

  • 신순식;최환수
    • 제3의학
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    • 제2권1호
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    • pp.35-54
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    • 1997
  • We tried to observe the features of ancient medical practice by analysing the records related to medicine in the book, ${\ulcorner}$the Historical Records of the Three Kingdom${\lrcorner}$ of which content includes the features of medicine in mythology, plague, delivery of twins, drugs, medical system, shamanism, constitutional medicine, psychiatry, forensic medicine, deformity, a spa, medical phrase, health and welfare work, religion, death. physiological anatomy, Taoist medicine, acupuncture, the occult af of transformation and etc. Our initial concern was about where to draw line as of medical field and we defined medicine in more broad meaning. The book ${\ulcorner}$the Historical Records of the Three Kingdoms${\lrcorner}$ describes the world of mythology by way of medicine which is not clearly a conventional one. There appears records of birth of multiple offsprings 7 times in which cases are of triplets or more. Delivering multiple offsprings were rare phenomenon though such fertility was highly admired. This shows one aspect of ancient country having more population meant more power of the nation. Of those medical records conveyed in that book includes stories of childbirth such as giving birth to a son after praying, giving birth to Kim Yoo-shin after 20 months after mother's dream of conception, and a song longing for getting a laudable child. Plagues were prevalent throughout winter to spring season and one can observe various symptoms of plagues in the record. Of these epidemic diseases, cold type might have been more common than the heat one. Appearance of epidemic diseases frequently coincided with that of natural disasters that this suggests a linkage between plague and underlying doctrine on five elements' motion and six kinds of natural factors. There exists only a few names of diseases such as epidemic disease, wind disease, and syndrome characterized by dyspnea. Otherwise there appeared only afflictions that were not specified therefore it remains cluless to keep track of certain diseases of prevalence. Since this ${\ulcorner}$Historical Records of the Three Kingdoms'${\lrcorner}$ wasn't any sort of medical book, words and terms used were not technical kind and most were the ones used generally among lay people. Therefore any mechanisms of the diseases were hardly mentioned. Some of medicinal substances such as Calculus Bovis, Radix Ginseng, Gaboderma Luciderm, magnetitum were also in use in those days. 53 kinds of dietary supplies appears in the records and some of these might have been used as medicinal purpose. Records concerning dicipline of one's body includes activities such as hunting, archery, horseback riding etc. In Shilla dynasty there were positions such as professor of medicine, Naekongbong(內供奉), Kongbong's doctor(供奉醫師), Kongbong's diviner(供奉卜師). As an educational facility, medical school was built at the first year of King Hyoso's reign and it's curricula included various subjects as ${\ulcorner}$Shin Nong's Herbal classic${\lrcorner}$, ${\ulcorner}$Kabeul classic of acupuncture and moxbustion${\lrcorner}$, ${\ulcorner}$The Plain Questions of the Yellow Emperor's Classic of Internal Medicine${\lrcorner}$, ${\ulcorner}$Classic of Acupuncturer${\lrcorner}$, ${\ulcorner}$The Pulse Classic${\lrcorner}$, ${\ulcorner}$Classic of Channels and Acupuncture Points${\lrcorner}$ and ${\ulcorner}$Difficult Classic${\lrcorner}$. There were 2 medical professors who were in charge of education. To establish pharmacopoeia, 2 Shaji(舍知), 6 Sha(史), 2 Jongshaji(從舍知) were appointed. In Baekje dynasty, Department of Herb was maintained. Doing praying for the sake of health, doing phrenology also can be extended to medical arena. Those who survived over 100 years of age appear 3 times in the record, while 98 appears once. The earliest psychiatrist Nokjin differentiated symptoms to apply either therapies using acupuncture and drug or psychotherapy. There appears a case of rape, a case of burying alive with the dead, 8 cases of suicide that can characterize a prototype of forensic medicine. Deformity-related records include phrases as follow: 'there seems protrudent bone behind the head', 'a body which has two heads, two trunks, four arms.', 'a body equipped with two heads' In those times spa can be said to be used as a place for he리ing, convalescence, and relaxation seeing the records describing a person pretended illness and went to spa to enjoy with his friends. Priest doctors and millitary surgeons were in charge of the medical sevice in the period of the Three Kingdoms by the record written by Mookhoja(墨胡子) and Hoonkyeom(訓謙). Poor diet and regimen makes people more vulnerable to diseases. So there existed charity services for those poor people who couldn't live with one's own capacity such as single parents, orphans, the aged people no one to take care and those who are ill. The cause of affliction was frequently coined with human relation. There appeared the phenomenon of releasing prisoners and allowing people to become priests at the time of king's suffering. Besides, as a healing procedure, sutra-chanting was peformed. There appears 10 cases of death related records which varies from death by drowning, or by freezing, death from animals, death from war, death from wightloss and killing oneself at the moment of spouse's death and etc. There also exist certain records which suggest the knowledge of physiology and anatomy in those times. Since the taoist books such as ${\ulcorner}$Book of the Way and Its Power(老子道德經)${\lrcorner}$ were introduced in the period of Three Kingdoms, it can be considered that medicine was also influenced by taoism. Records of higher level of acupuncture, records which links the medicine and occult art of transformation existed. Although limited, we could figure out the medical state of ancient society.

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종자내 아미노산 합성 조절 유전자에 관한 연구 (Amino Acid Biosynthesis and Gene Regulation in Seed)

  • 임용표;서미정;조수진;이정희;이효연
    • 한국식물학회:학술대회논문집
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    • 한국식물학회 1996년도 제10회 식물생명공학심포지움 고등식물 발생생물학의 최근 진보
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    • pp.61-74
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    • 1996
  • Human and monogastric animals can not synthesize 10 out of the 20 amino asids and therefor need to obtain these from their diet. The plant seed is a major source of dietary protein. It is particular important in their study to increase nutritional quality of the seed storage proteins. The low contents of lysine, asparagine and threonenein various cereal seeds and of cystein and methionine. In legume seeds is due to the low proportions of these amino acids in the major storage proteins, we have tried to apply the three strategies; (1) mutagenesis and selection of specific amino acid analogue resistance, (2) cloning and expression study of lysine biosynthesis related gene, (3) transfomation of lysine rich soybean glycinin gene. The 5-methyltryptophan (5MT) resistant cell lines, SAR1, SAR2 and SAR3 were selected from anther derived callus of rice (Oryza sativa L. "Sasanishiki"). Among these selected cell lines, two (SAR1 and SAR3) were able to grow stably at 200 mg/L of 5MT. Analysis of the freed amino acids in callus shows that 5MT resistant cells (SAR3) accumulated free tryptophan at least up to 50 times higher than those that of the higher than of SAS. These results indicated that the 5MT resistant cell lines are useful in studies of amino acid biosynthesis. Tr75, a rice (Oryza sativa L., var. Sasanishiki) mutant resistant to 5MT was segregated from the progenies of its initial mutant line, TR1. The 5MT resistant of TR75 was inherited in the M8 generations as a single dominant nuclear gene. The content of free amino acids in the TR75 homozygous seeds increased approximately 1.5 to 2.0 fold compared to wild-type seeds. Especially, the contents of tryptophan, phenylalanine and aspartic acid were 5.0, 5.3 and 2.7 times higher than those of wild-type seeds, respectively. The content of lysine is significantly low in rice. The lysine is synthesized by a complex pathway that is predominantly regulated by feedback inhibition of several enzymes including asparginase, aspatate kinase, dihydrodipicolinat synthase, etc. For understanding the regulation mechanism of lysine synthesis in rice, we try to clone the lysine biosynthetic metabolism related gene, DHPS and asparaginase, from rice. We have isolated a rice DHPS genomic clone which contains an ORF of 1044 nucleotides (347 amino acids, Mr. 38, 381 daltons), an intron of 587 nucleotides and 5'and 3'-flanking regions by screening of rice genomic DNA library. Deduced amino acid sequence of mature peptide domain of GDHPS clone is highly conserved in monocot and dicot plants whereas that of transit peptide domain is extremely different depending on plant specie. Southern blot analysis indicated that GDHPS is located two copy gene in rice genome. The transcripts of a rice GDHPS were expressed in leaves and roots but not detected in callus tissues. The transcription level of GDHPS is much higher in leaves indicating enormous chloroplast development than roots. Genomic DNA clones for asparaginase genes were screened from the rice genomic library by using plaque hybridization technique. Twelve different genomic clones were isolated from first and second screening, and 8 of 12 clones were analyzed by restriction patterns and identified by Southern Blotting, Restriction enzyme digestion patterns and Southern blot analysis of 8 clones show the different pattern for asparaginase gene. Genomic Southern blot analysis from rice were done. It is estimated that rice has at least 2-3 copy of asparaginase gene. One of 8 positive clones was subcloned into the pBluescript SK(+) vector, and was constructed the physical map. For transformation of lysine rich storage protein into tobacco, soybean glycinin genes are transformed into tobacco. To examine whether glycinin could be stably accumulated in endosperm tissue, the glycinin cDNA was transcriptionally fused to an endosperm-specific promotor of the rice storage protein glutelin gene and then introduced into tobacco genomic via Agrobacterium-mediated transformation. Consequently the glycinin gene was expressed in a seed-and developmentally-specific manner in transgenic tobacco seeds. Glycinin were targeted to vacuole-derived protein bodies in the endosperm tissue and highly accumulated in the matrix region of many transgenic plant (1-4% of total seed proteins). Synthesized glycinin was processed into mature form, and assembled into a hexamer in a similar manner as the glycinin in soybean seed. Modified glycinin, in which 4 contiguous methionine residues were inserted at the variable regions corresponding to the C - teminal regions of the acidic and basic polypeptides, were also found to be accumulated similarly as in the normal glycinin. There was no apparent difference in the expression level, processing and targeting to protein bodies, or accumulation level between normal and modified glycinin. glycinin.

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인체 폐암조직에서 Phospholipase C-$\gamma1$의 활성화 단백, AHNAK의 발현양상 (Increased Expression of Phospholipase C-$\gamma1$ Activator Protein, AHNAK in Human Lung Cancer Tissues)

  • 오윤정;박준성;최소연;정성철;이선민;황성철;이이형;한명호;이기범;류한영;하만준;배윤수;이서구
    • Tuberculosis and Respiratory Diseases
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    • 제47권3호
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    • pp.347-355
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    • 1999
  • 배경: Phospholipase C(PLC)는 세포의 성장, 분화, 변형(transformation)과 관련된 세포내 신호 전달과정에 중추적인 역할을 하는 효소이다. 이들 중 PLC-$\gamma$는 tyrosine kinase의 인산화에 의해 주로 활성화되는 데, 최근에 phosphatidic acid(PA), phosphatidy-linositol 3, 4, 5-trisphosphate($PIP_3$), tau 단백에 의한 활성화 기전이 밝혀진 바 있다. 특히 tau 단백은 bovine brain에서 arachidonic acid와 함께 PLC-$\gamma$를 활성화시키는 것으로 알려져 PLC-$\gamma$$PLA_2$ 사이의 cross-talk이 이루어질 가능성이 제시되고 있다. 최근 보고에 의하면 tau 단백과 같은 기전으로 PLC-${\gamma}1$ 활성화시키는 단백이 bovine lung에서 발견되었고, 이 활성화 단백을 정제 및 클론하여 AHNAK 단백임이 확인된 바 있다. 또한 PLC-${\gamma}1$이 유방암, 대장암, 위암 등에서 증가되어 있어 발암 과정과 연관되어 있음이 보고되어 왔으나 PLC-${\gamma}1$의 활성화 단백인 AHNAK 단백에 대해서는 질병과 관련되어 연구된 것이 아직 없는 실정이며 저자 등은 폐암 조직과 정상 폐조직에서 AHNAK 단백의 발현 양상을 연구하여 폐암의 발암과정에 AHNAK 단백이 관여함을 밝히고자 하였다. 대상 및 방법: 아주대학교 병원에 내원하여 폐암으로 수술을 받은 환자의 폐암 조직과 동일 환자의 정상 폐조직에서 AHNAK 단백의 발현양상을 western blot 분석과 면역조직화학적 염색방법을 통하여 조사하였다. 결과: 14예의 편평상피암 세포조직 중 8예 (57.1 %)와 14예의 선암 세포조직 모두에서 정상 대조군에 비해 AHNAK 단백의 발현이 증가하였고, 70 kDa~200kDa의 여러가지 분자량을 가지는 띠모양으로 나타났다. 면역조직화학적 염색에서도 정상 폐조직보다 폐암 조직내에서 강한 발색반응을 보였다. 결론: PLC-${\gamma}1$의 활성화 단백인 AHNAK 단백이 폐암 조직에서 정상 조직보다 과발현된 것은, AHNAK 단백이 PLC-${\gamma}1$을 활성화시켜 폐암의 발생 기전에 관여할 수 있음을 뒷받침한다고 하겠다.

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