• Journal of Digital Convergence
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• v.17 no.12
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• pp.555-563
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• 2019

This study was to provide quantitative basic data on the forehand and backhand throw movements of flying disks. For this purpose, the kinematic variables were calculated using the three-dimensional motion analysis system. A comprehensive analysis of the study variables showed that it is important to throw flying disks accurately as well as far away, so in P2 and P3 it is necessary to control forward movement and concentrate on the rotation of the joints. In addition, rotational force transfer from pelvis to body is considered important for efficient rotational movement. The forehand was found to mainly utilize the movement of the upper extremity joint to perform throwing motion, while the backhand throw was found to be relatively utilized for the rotation of the torso and pelvis. Based on the quantitative data of this study, we hope that it can be used as a basic material for on-site training of Flying Discs.

• The Journal of the Acoustical Society of Korea
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• v.20 no.1
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• pp.13-20
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• 2001

Adaptive digital filters with long impulse response such as acoustic echo canceller and active noise controller suffer from slow convergence and computational burden. Subband techniques and multirate signal processing have been recently developed to improve the problem of computational complexity and slow convergence in conventional adaptive filter. Any FIR transfer function can be realized as a serial connection of interpolators followed by subfilters with a sparse impulse response. In this case, each interpolator which is related to the column vector of Hadamard matrix has band-pass magnitude response characteristics shifted uniformly. Subband technique using Hadamard transform and decimation of subband signal to reduce sampling rate are adapted to system modeling and acoustic noise cancellation In this paper, delayless subband structure with nonuniform bandwidth has been proposed to improve the performance of the convergence speed without aliasing due to decimation, where input signal is split into subband one using tree-structured filter bank, and the subband signal is decimated by a decimator to reduce the sampling rate in each channel, then subfilter with sparse impulse response is transformed to full band adaptive filter coefficient using Hadamard transform. It is shown by computer simulations that the proposed method can be adapted to general adaptive filtering.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2009.10a
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• pp.243-244
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• 2009

From large to small vessels of the surface is not smooth. and The surface ship has a surface roughness. Because surface roughness increases the surface resistance and heat transfer, be considered when designing a ship that is an important design factor. Due to surface roughness study on flow around and due to changes in flow and turbulence intensity for the ongoing research is conducted. Roughness of the surface ships from the ship by air as well as machines can be widely applied. In this study, the surface roughness of the leisure marine interval, any change will affect the surface flow, area due to surface roughness for boundary-experimental study was performed.

• Korean Journal of Plant Tissue Culture
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• v.21 no.5
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• pp.315-318
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• 1994

To obtain transformed plants, we cocultured cotyledonary explants of Codonopsis lanceolata with Agrobacterium tumefaciens LBA4404, a disamed strain harboring a binary vector pBI121 carrying the CaMV35S promoter-$\beta$-glucuronidase (GUS) gene fusion used as a reporter gene and NOS promoter-neomycin phosphotransferase gene as a positive selection marker in MS liquid medium with 1mg/L BA. After 48 h of culture, explants were transferred onto MS solid medium with Img/L BA, 250mg/L carbenicillin, and 100mg/L kanamycin sulfate and cultured in the dark. Numerous adventitious buds formed on the cut edges of the explants after 2 weeks of culture. When subjected to GUS histochemical assay buds showed a positive response at a frequency of 15%. Explants formed adventitious shoot at a frequency of 56.7%, after 6 weeks of culture. Upon transfer onto the basal medium, most of the shoots were rooted and subsequently the regenerants were transplanted to potting soil. Southern blot analysis confirmed that the GUS gene was incorporated into the genomic DNA of the GUS-positive regenerants.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.626-626
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• 2015

본 연구에서는 하천공간정보의 웹서비스를 위해 SOAP(Simple Object Access Protocol) API 및 REST(Representation State Transfer) API로 제공하는 HydroG-OneFlow 웹서비스를 개발하였다. HydroG-OneFlow는 GML 기반의 서비스를 제공하며 GetBasin, GetGeoVariable 및 GetData 등의 기본서비스로 구성된다. GML은 GIS S/W의 벡터 GML 포맷과 공간정보 오픈플랫폼 서비스인 브이월드 데이터 API에서 제공하는 GML 포맷을 참고하여 하천공간 벡터정보를 제공할 수 있도록 GML을 구성하였다. GDM 공간 데이터에 대한 벡터정보 ML 수용 수준을 향상시킬 수 있도록 벡터구조의 점, 선, 면 정보에 대하여 GML의 PointPropertyType, CurvePropertyType, SurfacePropertyType을 도입하였다. 또한 일반적인 공간자료에서는 Multi 객체에 대한 지원도 필요하다. 현 GDM 데이터베이스에서도 OGC 표준의 MultiPoint, MultiLineString, MultiPolygon을 지원하고 있다. 이를 위하여 GML의 상응 요소인MultiPointPropertyType, MultiCurvePropertyType, MultiSurfacePropertyType을 하천공간정보 벡터 스키마에 도입하여 활용하였다. 클라이언트 서버 통신은 메시지 교환프로토콜인 SOAP을 사용하여 서버의 객체를 직접 호출하여 이루어진다. 서버는 서버의 제공 서비스를 WSDL(Web Service Description Language)를 통하여 게시하고 클라이언트는 이 기준(Criteria)을 참고하여 접근한다. GetData의 경우 Type(GRID or VECTOR), GDM(Geospatial Data Model) 여부(true or false), LayerName, BasinID, GenTime을 인자로 받아 GeoData에서 검색된 정보를 반환한다. SOAP버전은 1.1과 1.2를 지원하여 접근하는 클라이언트에서 선택할 수 있도록 개발하였다.

• Mycobiology
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• v.49 no.5
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• pp.491-497
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• 2021

An endolichenic fungus Xylaria grammica EL000614 produces grammicin, a potent nematicidal pyrone derivative that can serve as a new control option for root-knot nematodes. We optimized an Agrobacterium tumefaciens-mediated transformation (ATMT) protocol for X. grammica to support genetic studies. Transformants were successfully generated after co-cultivation of homogenized young mycelia of X. grammica with A. tumefaciens strain AGL-1 carrying a binary vector that contains the bacterial hygromycin B phosphotransferase (hph) gene and the eGFP gene in T-DNA. The resulting transformants were mitotically stable, and PCR analysis showed the integratin of both genes in the genome of transformants. Expression of eGFP was confirmed via fluorescence microscopy. Southern analysis showed that 131 (78.9%) out of 166 transformants contained a single T-DNA insertion. Crucial factors for producing predominantly single T-DNA transformants include 48 h of co-cultivation, pretreatment of A. tumefaciens cells with acetosyringone before co-cultivation, and using freshly prepared mycelia. The established ATMT protocol offers an efficient tool for random insertional mutagenesis and gene transfer in studying the biology and ecology of X. grammica.

• Journal of Microbiology and Biotechnology
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• v.31 no.4
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• pp.570-583
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• 2021

Pyrococcus furiosus α-amylase can hydrolyze α-1,4 linkages in starch and related carbohydrates under hyperthermophilic condition (~ 100℃), showing great potential in a wide range of industrial applications, while its relatively low productivity from heterologous hosts has limited the industrial applications. Bacillus subtilis, a gram-positive bacterium, has been widely used in industrial production for its non-pathogenic and powerful secretory characteristics. This study was conducted to increase production of P. furiosus α-amylase in B. subtilis through three strategies. Initial experiments showed that co-expression of P. furiosus molecular chaperone peptidyl-prolyl cis-trans isomerase through genomic integration mode, using a CRISPR/Cas9 system, increased soluble amylase production. Therefore, considering that native P. furiosus α-amylase is produced within a hyperthermophilic environment and is highly thermostable, heat treatment of intact culture at 90℃ for 15 min was performed, thereby greatly increasing soluble amylase production. After optimization of the culture conditions (nitrogen source, carbon source, metal ion, temperature and pH), experiments in a 3-L fermenter yielded a soluble activity of 3,806.7 U/ml, which was 3.3- and 28.2-fold those of a control without heat treatment (1,155.1 U/ml) and an empty expression vector control (135.1 U/ml), respectively. This represents the highest P. furiosus α-amylase production reported to date and should promote innovation in the starch liquefaction process and related industrial productions. Meanwhile, heat treatment, which may promote folding of aggregated P. furiosus α-amylase into a soluble, active form through the transfer of kinetic energy, may be of general benefit when producing proteins from thermophilic archaea.

• International Journal of Computer Science & Network Security
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• v.22 no.9
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• pp.195-207
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• 2022

COVID-19 has remained one of the most serious health crises in recent history, resulting in the tragic loss of lives and significant economic impacts on the entire world. The difficulty of controlling COVID-19 poses a threat to the global health sector. Considering that Artificial Intelligence (AI) has contributed to improving research methods and solving problems facing diverse fields of study, AI algorithms have also proven effective in disease detection and early diagnosis. Specifically, acoustic features offer a promising prospect for the early detection of respiratory diseases. Motivated by these observations, this study conceptualized a speech-based diagnostic model to aid in COVID-19 diagnosis. The proposed methodology uses speech signals from confirmed positive and negative cases of COVID-19 to extract features through the pre-trained Visual Geometry Group (VGG-16) model based on Mel spectrogram images. This is used in addition to the K-means algorithm that determines effective features, followed by a Genetic Algorithm-Support Vector Machine (GA-SVM) classifier to classify cases. The experimental findings indicate the proposed methodology's capability to classify COVID-19 and NOT COVID-19 of varying ages and speaking different languages, as demonstrated in the simulations. The proposed methodology depends on deep features, followed by the dimension reduction technique for features to detect COVID-19. As a result, it produces better and more consistent performance than handcrafted features used in previous studies.

• Journal of radiological science and technology
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• v.46 no.5
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• pp.379-394
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• 2023

Targeted Alpha Therapy (TAT) is a new method of cancer treatment that protects normal tissues while selectively killing tumor cells using high cytotoxicity and short range of alpha particles, and target alpha therapy is a highly specific and effective cancer treatment strategy, and its potential has been proven through many clinical and experimental studies. This treatment method accurately delivers alpha particles by selecting specific molecules present in cancer tissue, which has an effective destruction and tumor suppression effect on cancer cells, and one of the main advantages of target alpha treatment is the physical properties of alpha particles. Alpha particles have a very high energy and short effective distance, interacting with target molecules in cancer tissues and having a fatal effect on cancer cells, which is known to cause DNA damage and cell death in cancer cells. TAT has shown positive results in preclinical and clinical studies for various types of cancers, especially those that resist or are unresponsive to existing treatments, but there are several challenges and limitations to overcome for successful clinical transition and application. These include the provision and production of suitable alpha radioisotopes, optimization of target vectors and delivery formulations, understanding and regulation of radiological effects, accurate dosage calculation and toxicity assessment. Future research should focus on developing new or improved isotopes, target vectors, transfer formulations, radiobiological models, combination strategies, imaging techniques, etc. for TAT. In addition, TAT has the potential to improve the quality of life and survival of cancer patients due to the possibility of a new treatment for overcoming cancer, and to this end, prospective research on more carcinomas and more diverse patient groups is needed.

• Journal of Astronomy and Space Sciences
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• v.40 no.4
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• pp.199-215
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• 2023

The Korea Pathfinder Lunar Orbiter (KPLO), the first South Korea lunar exploration probe, successfully arrived at the Moon on December, 2022 (UTC), following a 4.5-month ballistic lunar transfer (BLT) trajectory. Since the launch (4 August, 2022), the KPLO magnetometer (KMAG) has carried out various observations during the trans-lunar cruise phase and a 100 km altitude lunar polar orbit. KMAG consists of three fluxgate magnetometers capable of measuring magnetic fields within a ± 1,000 nT range with a resolution of 0.2 nT. The sampling rate is 10 Hz. During the originally planned lifetime of one year, KMAG has been operating successfully while performing observations of lunar crustal magnetic fields, magnetic fields induced in the lunar interior, and various solar wind events. The calibration and offset processes were performed during the TLC phase. In addition, reliabilities of the KMAG lunar magnetic field observations have been verified by comparing them with the surface vector mapping (SVM) data. If the KPLO's mission orbit during the extended mission phase is close enough to the lunar surface, KMAG will contribute to updating the lunar surface magnetic field map and will provide insights into the lunar interior structure and lunar space environment.