• Advances in nano research
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• v.13 no.3
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• pp.217-231
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• 2022

This study investigates the geometrical impact on the nanomedicine drug delivery via nanodevices. A nanomotor made of the nanotube carrying the drug as the motor blade is considered in the blood flow. Physical activities change the blood flow, and sports training enhances the blood flow and plays a significant role in the stability of drug delivery devices. This paper studies the impact of geometrical parameters on the nanomotors carrying the nanomedicine. The effect of physical exercise on the dynamic response regarding the stability of drug delivery devices is discussed in detail.

• Structural Engineering and Mechanics
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• v.84 no.1
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• pp.35-48
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• 2022

This paper investigates the artificial neural network (ANN) to predict the dimensionless parameters for contact pressures and contact lengths under the rigid punch, the initial separation loads, and the initial separation distances of a contact problem. The problem consisted of two elastic infinitely layers (EL) loaded by means of a rigid cylindrical punch and resting on a half-infinite plane (HP). Firstly, the problem was formulated and solved theoretically using the Theory of Elasticity (ET). Secondly, the contact problem was extended based on the ANN. External load, the radius of punch, layer heights, and material properties were created by giving examples of different values used at the training and test stages of ANN. Finally, the accuracy of the trained neural networks for the case was tested using 134 new data, generated via ET solutions to determine the best network model. ANN results were compared with ET results, and well agreements were achieved.

• Structural Engineering and Mechanics
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• v.85 no.1
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• pp.15-27
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• 2023

Using artificial intelligence and internet of things methods in engineering and industrial problems has become a widespread method in recent years. The low computational costs and high accuracy without the need to engage human resources in comparison to engineering demands are the main advantages of artificial intelligence. In the present paper, a deep neural network (DNN) with a specific method of optimization is utilize to predict fundamental natural frequency of a cylindrical structure. To provide data for training the DNN, a detailed numerical analysis is presented with the aid of functionally modified couple stress theory (FMCS) and first-order shear deformation theory (FSDT). The governing equations obtained using Hamilton's principle, are further solved engaging generalized differential quadrature method. The results of the numerical solution are utilized to train and test the DNN model. The results are validated at the first step and a comprehensive parametric results are presented thereafter. The results show the high accuracy of the DNN results and effects of different geometrical, modeling and material parameters in the natural frequencies of the structure.

• Wind and Structures
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• v.34 no.3
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• pp.259-274
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• 2022

The present paper is focused on analyzing a set of Computational Fluid Dynamics (CFD) simulation data on reducing orthogonal peak base moment coefficients on a high-rise rectangular building with wings. The study adopts an aerodynamic optimization procedure (AOP) composed of CFD, artificial neural network (ANN), and genetic algorithm (G.A.). A parametric study is primarily accomplished by altering the wing positions with 3D transient CFD analysis using k - ε turbulence models. The CFD technique is validated by taking up a wind tunnel test. The required design parameters are obtained at each design point and used for training ANN. The trained ANN models are used as surrogates to conduct optimization studies using G.A. Two single-objective optimizations are performed to minimize the peak base moment coefficients in the individual directions. An additional multiobjective optimization is implemented with the motivation of diminishing the two orthogonal peak base moments concurrently. Pareto-optimal solutions specifying the preferred building shapes are offered.

• Biomolecules & Therapeutics
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• v.30 no.1
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• pp.1-18
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• 2022

Drug-drug interactions are a major cause of hospitalization and deaths related to drug use. A large fraction of these is due to inhibition of enzymes involved in drug metabolism and transport, particularly cytochrome P450 (P450) enzymes. Understanding basic mechanisms of enzyme inhibition is important, particularly in terms of reversibility and the use of the appropriate parameters. In addition to drug-drug interactions, issues have involved interactions of drugs with foods and natural products related to P450 enzymes. Predicting drug-drug interactions is a major effort in drug development in the pharmaceutical industry and regulatory agencies. With appropriate in vitro experiments, it is possible to stratify clinical drug-drug interaction studies. A better understanding of drug interactions and training of physicians and pharmacists has developed. Finally, some P450s have been the targets of drugs in some cancers and other disease states.

• Steel and Composite Structures
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• v.46 no.1
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• pp.107-114
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• 2023

A new intelligent adaptive control scheme was proposed that combines observer disturbance-based adaptive control and fuzzy adaptive control for a composite structure with a mass-adjustable damper. The most important advantage is that the control structures do not need to know the uncertainty limits and the interference effect is eliminated. Three adjustable parameters in LMI are used to control the gain of the 2D fuzzy control. Binary performance indices with weighted matrices are constructed to separately evaluate validation and training performance using the revalidation learning function. Determining the appropriate weight matrix balances control and learning efficiency and prevents large gains in control. It is proved that the stability of the control system can be ensured by a linear matrix theory of equality based on Lyapunov's theory. Simulation results show that the multilevel simulation approach combines accuracy with high computational efficiency. The M-TMD system, by slightly reducing critical joint load amplitudes, can significantly improve the overall response of an uncontrolled structure.

• Advances in nano research
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• v.13 no.5
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• pp.487-497
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• 2022

This study investigates the stability of protein tissues regarding the vibration analysis based on the classical beam theory coupled with the nonlocal elasticity theory concerning the exercise impact. As reported in the previous research, four different types of protein tissues are supposed, and the influence of sports training is investigated. The protein tissues are made of protein fibers surrounded by an elastic foundation. The exercise enhances the muscle area and plays an essential role in the stability and strength of protein and muscle tissues. The results are examined in detail to examine the impact of different parameters on the stability of nano protein fibers.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2022.11a
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• pp.170-171
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• 2022

A ship's maneuvering motion model is important in a computer simulation, especially under the trend of intelligent navigation. This model is usually constructed by the hydrodynamic parameters of the ship which are generated by the principles of hydrodynamics. Ship's motion model is a nonlinear function. By using this function, ships' motion elements can be calculated, then the ship's trajectory can be predicted. Deeping neural networks can construct any linear or non-linear equation theoretically if there have enough and sufficient training data. This study constructs some kinds of deep Networks and trains this network by real ship motion data, and chooses the best one of the networks, uses real data to train it, then uses it to predict the ship's trajectory, getting some conclusions and experiences.

• Computers and Concrete
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• v.32 no.6
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• pp.607-613
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• 2023

The objective of this work is to determine the compressive strength of geopolymer concrete utilizing four distinct machine learning approaches. These techniques are known as gradient boosting machine (GBM), generalized linear model (GLM), extremely randomized trees (XRT), and deep learning (DL). Experimentation is performed to collect the data that is then utilized for training the models. Compressive strength is the response variable, whereas curing days, curing temperature, silica fume, and nanosilica concentration are the different input parameters that are taken into consideration. Several kinds of errors, including root mean square error (RMSE), coefficient of correlation (CC), variance account for (VAF), RMSE to observation's standard deviation ratio (RSR), and Nash-Sutcliffe effectiveness (NSE), were computed to determine the effectiveness of each algorithm. It was observed that, among all the models that were investigated, the GBM is the surrogate model that can predict the compressive strength of the geopolymer concrete with the highest degree of precision.

• International Journal of Computer Science & Network Security
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• v.24 no.2
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• pp.1-14
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• 2024

While text-to-image models have made remarkable progress in image synthesis, certain models, particularly generative diffusion models, have exhibited a noticeable bias to- wards generating images related to the culture of some developing countries. This paper introduces an empirical investigation aimed at mitigating the bias of image generative model. We achieve this by incorporating symbols representing Saudi culture into a stable diffusion model using the Dreambooth technique. CLIP score metric is used to assess the outcomes in this study. This paper also explores the impact of varying parameters for instance the quantity of training images and the learning rate. The findings reveal a substantial reduction in bias-related concerns and propose an innovative metric for evaluating cultural relevance.