• International Journal of Human Ecology
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• v.11 no.1
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• pp.109-119
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• 2010

Modernization of cities and housing in Malaysia is a reflection of the history of the establishment of colonial trading ports for worldwide maritime trade and exchange. In cosmopolitan cities, new housing typology appeared from the influence of various ethnic immigrants and with the fusion of traditional Malay housing characteristics. This study is to focus on classifying the housing typologies of Malaysia which were formed through the modernization process of cities. The typologies of modern housing in Malaysia can be classified into two categories. The first category is the 'transformation of traditional housing'. The representative typology of this group is the ubiquitous shophouse. The shophouse was originally brought in by the Chinese immigrants from the south coast of China and transformed into the Malaysian urbanscape. The other typology is a detached-house known as the bungalo, which was the housing style combining the Malay traditional timber house and European palazzo. The second category is the 'modern urban housing typology'. Modern urbanization after the independence from the British in 1957 required the maximum utilization of land. To accommodate new social and economic needs, the new typologies were developed in the form of medium-density terrace houses (row houses) and high-density apartment. In the suburban areas, the British terrace house was adopted and developed into unique Malaysian terrace house and semi-detached house based on the British system of land sub division. In premium area of the city, luxurious housing type in the form of high-end condominium is one of the popular housing for upper middle-class and high-class society.

• Textile Coloration and Finishing
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• v.24 no.4
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• pp.260-269
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• 2012

The aim of this study was to develop higher-value added dyeing materials with the fermentation-dyeing -mordanting system using only the natural ingredients by integrating traditional fermentation techniques with traditional dyeing technique. Nuruk, which is used mainly to ferment traditional foods, was used as a fermenting agent to ferment 5 different types of materials. Acidic burnt alum and alkaline calcium hydroxide were used as natural mordants. The dyeability checked after fermentation showed that both cotton and silk mordanted with Gardenia jasminoides did not show notable changes, and 10 days of fermentation was found to be appropriate. Sophora japonica L. performed better on cotton materials mordanted with slaked lime, and alkaline mordants were found to be more effective than acidic ones. With Rheum coreanum, a fermentation period of more than 24 days ($5^{th}$ fermentation) worked best on cotton material, showing a 5 fold increase in the K/S value after the $5^{th}$ slaked lime fermentation than with no fermentation. Rhus javanica L. was found to increase the color fastness to gentle washing and the fastness to light was found to possess 4 means that natural dyed fabric have the highest level of durability, the grade 1 the lowest level of fastness.

• Journal of Intelligence and Information Systems
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• v.18 no.2
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• pp.131-141
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• 2012

In this paper, we propose a new method for collaborative filtering (CF)-based recommender systems. Traditional CF-based recommendation algorithms have applied constant settings such as a reference group (neighborhood) size and a significance level to all users. In this paper we develop a new method that identifies optimal personalized settings for each user and applies them to generating recommendations for individual users. Personalized parameters are identified through iterative simulations with 'training' and 'verification' datasets. The method is compared with traditional 'constant settings' methods using Netflix data. The results show that the new method outperforms traditional, ordinary CF. Implications and future research directions are also discussed.

• The Journal of Korean Medicine
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• v.39 no.4
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• pp.126-135
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• 2018

Objectives: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and irreversible airflow. This study aimed to evaluate the effects of GHX02 in a COPD-induced mouse model. Methods: The COPD mouse model was established by exposure to cigarette smoke extract and lipopolysaccharide which were administered by intratracheal injection three times with a 7 day interval. GHX02 (100, 200, 400 mg/kg) and all other drugs were orally administrated for 14 days from Day 7 to Day 21. Results: GHX02 significantly decreased the neutrophil counts in bronchoalveolar lavage fluid (BALF) and the number of $CD4^+$, $CD8^+$, $CD69^+$, and $CD11b^+/GR1^+$ cells in BALF and lung cells. GHX02 also suppressed the secretion of tumor necrosis factor-alpha ($TNF-{\alpha}$), interleukin-17A, macrophage inflammatory protein 2 (MIP2), and chemokine (C-X-C motif) ligand 1 (CXCL-1) in BALF and ameliorated the lung pathological changes. Conclusions: Thus, GHX02 effectively inhibited airway inflammation by inhibiting migration of inflammatory cells and expression of pro-inflammatory cytokines. Therefore, GHX02 may be a promising therapeutic agent for COPD.

• Journal of the Korean Society of Clothing and Textiles
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• v.42 no.6
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• pp.924-942
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• 2018

This study is to understand the symbolism and meaning of Yeomim in Korean traditional clothing. Throughout the study, literature research and analysis have been conducted along with empirical studies. The results of the study are as follows. First, there are three types of Yeomim for Korean clothing. Various methods of Yeomim use different materials for tying clothes such as straps and buttons. Second, when we investigate how Yeomim of Korean clothing has evolved, left and right type of Yeomim had coexisted in ancient times and Dae had been used mainly to tie clothes. The Yeomim method has used various materials since the Goryeo Dynasty. During the Joseon Dynasty, right type Yeomim dominated with majority using Goreum. Third, Hanbok has consistently evolved with a unique bonding style that uses rectangular strap for Yeomim, from the ancient times. The particular Yeomim method of twisting a rectangular strap represents the circularity of space. In addition, Yeomim with a strap is characterized by the beauty of how its form can be highly flexible depending on the human body or location of Yeomim, which corresponds to an unbalanced and asymmetrical natural beauty unique to Korea.

• Journal of Multimedia Information System
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• v.9 no.1
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• pp.21-32
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• 2022

Early-stage diagnosis of Alzheimer's Disease (AD) from Cognitively Normal (CN) patients is crucial because treatment at an early stage of AD can prevent further progress in the AD's severity in the future. Recently, computer-aided diagnosis using magnetic resonance image (MRI) has shown better performance in the classification of AD. However, these methods use a traditional machine learning algorithm that requires supervision and uses a combination of many complicated processes. In recent research, the performance of deep neural networks has outperformed the traditional machine learning algorithms. The ability to learn from the data and extract features on its own makes the neural networks less prone to errors. In this paper, a dense neural network is designed for binary classification of Alzheimer's disease. To create a classifier with better results, we studied result of different activation functions in the prediction. We obtained results from 5-folds validations with combinations of different activation functions and compared with each other, and the one with the best validation score is used to classify the test data. In this experiment, features used to train the model are obtained from the ADNI database after processing them using FreeSurfer software. For 5-folds validation, two groups: AD and CN are classified. The proposed DNN obtained better accuracy than the traditional machine learning algorithms and the compared previous studies for AD vs. CN, AD vs. Mild Cognitive Impairment (MCI), and MCI vs. CN classifications, respectively. This neural network is robust and better.

• BMB Reports
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• v.56 no.11
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• pp.594-599
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• 2023

A number of therapeutic drugs have been developed from functional chemicals found in plants. Knowledge of plants used for medicinal purposes has historically been transmitted by word of mouth or through literature. The aim of the present study is to provide a systemic platform for the development of lead compounds against breast cancer based on a traditional medical text. To verify our systematic approach, integrating processes consisted of text mining of traditional medical texts, 3-D virtual docking screening, and in vitro and in vivo experimental validations were demonstrated. Our text analysis system identified rutin as a specific phytochemical traditionally used for cancer treatment. 3-D virtual screening predicted that rutin could block EGFR signaling. Thus, we validated significant anti-cancer effects of rutin against breast cancer cells through blockade of EGFR signaling pathway in vitro. We also demonstrated in vivo anti-cancer effects of rutin using the breast cancer recurrence in vivo models. In summary, our innovative approach might be proper for discovering new phytochemical lead compounds designing for blockade of malignant neoplasm including breast cancer.

• Nuclear Engineering and Technology
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• v.56 no.5
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• pp.1638-1653
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• 2024

Given the unpredictability of the occurrence of the earthquake and other potential disasters into consideration, the nuclear power plant may be confronted with beyond design-basis earthquake load in the future. The containment structure may be severely damaged under such severe earthquake loading, increasing the risk of containment concrete cracking and potential radioactive materials leaking. Moreover, initial damage caused by the earthquake may significantly alter the pressure performance of the containment under follow-up internal pressure. To compromise the dangers of beyond design-basis earthquake to the containment, an alternative of replacing the conventional concrete with fiber-reinforced concrete (FRC) to upgrade the seismic resistance capacity of the containment is attempted and thoroughly researched. In this study, the influence of various fiber types such as rigid fiber and mixed fiber is regarded to constitute fiber-reinforced PCCVs. The physical properties of traditional and fiber-reinforced PCCVs under earthquake ground motions are scientifically compared and identified by using traditional and proposed evaluation indices. The results indicate that both the traditional evaluation index (i.e. top displacement, stress, strain) and the proposed damage index are greatly reduced by the practice of fiber strengthening under earthquake ground motions.

• Journal of Power System Engineering
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• v.7 no.1
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• pp.74-81
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• 2003

A system identification is to estimate the mathematical model on the base of input output data and to measure the output in the presence of adequate input for the controlled system. In the traditional system control field, most identification problems have been thought as estimating the unknown modeling parameters on the assumption that the model structures are fixed. In the system identification, it is possible to estimate the true parameter values by the adjusted least squares method in the input output case of no observed noise, and it is possible to estimate the true parameter values by the total least squares method in the input output case with the observed noise. We suggest the adjusted least squares method as a consistent estimation method in the system identification in the case where there is observed noise only in the output. In this paper the adjusted least squares method has been developed from the least squares method and the efficiency of the estimating results was confirmed by the generating data with the computer simulations.

• Journal of the Korean Society for Precision Engineering
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• v.19 no.1
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• pp.127-134
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• 2002

This study present a direct steering system using rack and pinion for ultra-small vehicles. The traditional small vehicles for special use had the limitation of space by reason of short wheel tread. These vehicles has adopted a indirect steering system or a center arm system for steering. The disadvantages of these system were deterioration of gear efficiency and increase of parts. For direct-linkage to both knuckles, steering system is made up of out-side tie rods, tie-rod ends, and gear box. Thus, the proposed system has a minimum number of parts. The experimental results show a maximum efficiency at minimum steering angle and a minimum clearance circle. These effects were accomplished by adopting a Ackerman-Jantaud theory.