• 대한한의학방제학회지
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• 제15권1호
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• pp.117-128
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• 2007

We re-classified traditional medicinal prescriptions in Dong-Eui-Bo-Gam for the modern application using Tradimed database. They could be devided into 6 categories by the definitions of the related laws. Herbal ethical drugs are the majority, 3926 items, account for 60.21% of total items. Herbal Health Functional Foods stands second, 1480 items, 22.70%, Herbal over the counter drugs are 893 items, 13.69%. These three categories are about 83% of total items. Herbal medical supplies are 158 items, 2.42%, Herbal medical tools are 44 items, 0.67%, Herbal cosmetics are 20 items, occupied 0.31 %. Therefore we have known that traditional medicinal prescriptions can be used not only as drugs, but also as funtional foods, cosmetics, and tools. So they should be developed as modern products to make best use of them. And we suggested that we need official criteria of herbs of careful use and higher standards for herbs which can be used as foods.

• 한국의사학회지
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• 제23권1호
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• pp.11-22
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• 2010

This study finds an interesting fact that five symptoms (smallpox, postpartum pain, eye disease, swollen symptom and parasite infection) mentioned in Ryu Ei-Tae Medicinal Tales and his prescriptions (steamed rice, loess, soybean sprouts, cinnabar, radish, sesame oil and pork) were dramatized on the basis of traditional Korean medicinal knowledge in the Joseon Dynasty. Based on the study of experience-based medicinal literatures popular in the Joseon period, it is confirmed that the prescriptions are actually effective. Also it is inferred that popular diseases at that time were abscess, difficult baby delivery, postpartum pain and parasite infection, which were regarded as almost incurable diseases to ordinary people. These stories also showed destitution of common people who could not afford to buy medicines at that time. As shown in the Ryu Ei-Tae Medicinal Fable, many people might try various ordinary materials around them such as soil or nose wax. One of the outcomes of this study is that the fact that the tales mentioned common materials easy to get in the surroundings such as steamed rice, sesame oil, soybean sprouts or radish could be interprets as care and consideration of medicinal doctors for ordinary people at that time.

• 대한예방한의학회지
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• 제17권1호
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• pp.125-135
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• 2013

Objectives : Medical treating with eating foods is one of important therapies in East Asian traditional medical knowledge and is referred as a therapy to treat diseases through foods. Since the food cannot be separated from ordinary people living, the medical treating with eating foods is a therapy with strong locality and contains many autogenous parts. Methods : Recently, the world is showing much interest for genetic resources, and the concept of intellectual property is rapidly expanding as the field of 'new knowledge property right' as well. Thus, the knowledge of medical treating with eating foods recently draws much attention in the economic aspect beyond the scholarly interest for traditional medicine. Here, I would like to summarize and report the contents related to medical treating with eating foods on "Yi, SeikKan experience prescriptions" which was discovered before. Results & Conclusions : First, medical treating with eating porridge on "Yi, SeikKan experience prescriptions" is classified into one with nonglutinous rice as the main ingredient and the other with other grains as the main ingredient. It is differently utilized depending on the nature of the grain. Second, medical treating with eating rice on "Yi, SeikKan experience prescriptions" was born from our nation's unique way of living and is classified into one way to eat rice mixed with ground medicinal herbs, another one to cook and eat rice with mixed grains and the other way to use as the external application. Medical treating with eating rice is assumed to replace the meal. Third, "food section" was given separately and discussed in this book. There were some parts different from existing medical knowledge due to the accumulation of experience using medicinal herbs. Fourth, we should pay attention to experience a book on medicine where vibrant medical information has been recorded in order to discover and process our traditional knowledge resources as a useful form.

• 생약학회지
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• 제8권1호
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• pp.1-15
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• 1977

In an attempt to deduce which plants might have been used for their anticancer activities in traditional oriental herb medicine, 127 prescriptions were selected from 'Dong-Eui-Bo-Gam', the Classic Handbook of Korean Traditional Medicine, written by $H_{UH}$ Jun and published in 1613. These are the prescriptions indicated for the systemic treatment of various tumors and some conditions resembling tumors, e.g. inflammatory masses and indurations, and they include 150 natural products of plant origin. The frequency of appearance of each medicinal plant in these selected prescriptions was compared with the frequency of its appearance in all prescriptions listed in 'Bang-Yak-Hap-Pyon', another popular Oriental Medicine Formulary in Korea, written by $H_{WANG}\;Pil-Su$ in 1885. From the latter book, $H_{ONG}$ has recently enumerated frequencies of 235 medicinal plants included in a total of 467 prescriptions. Chi-square tests revealed that 11 plant remedies appear with significantly higher frequency in the prescriptions for "tumors", and 10 for "inflammations". The plants with potential antitumor activities, in decreasing order of statistical significance, are Scirpus maritimus, Curcuma zedoaria, Prunus persica, Rheum coreanum, Foeniculum vulgare, Rhus vernifera, Daphne pseudogenkwa, Galarhaeus sieboldiana, Croton tiglium, Raphanus sativus and Galarhaeus pekinensis. The drugs for potential antibacterial or anti-inflammatory activities are Olibanum(Frankincense), Forsythia coreana, Lonicera japonica, Gleditchia officinalis, $M_{YRRH}$, Trichosanhes kirilowii, Astragalus membranaceus, Rheum coreanum, Platycodon grandiflorum and Fritillaria verticillata. Despite the uncertainties involved in the terminology of various diseases used in pre-modern medicine, and the reservations about the efficacy of remedies used for those diseases, it would be worthwhile to investigate these few selected plants for anticancer, antibacterial, anti-inflammatory or antifungal effects, employing modern scientific methodology.

• 동의생리병리학회지
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• 제21권6호
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• pp.1365-1380
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• 2007

Based on the theories and clinical data of oriental medicine, traditional medicinal prescriptions known to be effective to diabetic nephropathy were collected. The prescriptions were carefully examined and analyzed in order to be used as fundamental material for experiments and in clinicals. More than 40 publications related to diabetes were arranged and analyzed. Of the complications, diabetic nephropathy part of the publications were specifically focused during analysis. Data were analyzed and classified according to the quantity, prescription, differentiation of symptoms, signs and addition and subtraction of each medicine. Frequently used medicines were statistically analyzed. The most frequently used prescription was Yukmigihwang-tang(六味地黃湯) based medicine and prescriptions of its addition and subtraction, which was 15% of the total prescriptions cited. The most frequently used medicine was Astragali Radix, mentioned 192 times in the prescriptions. Hoelen was next with 180 citations, followed by Dioscoreae Rhizoma with 147 times, Rehmanniae Radix with 140, Corni Fructus with 131, Salviae Miltiorrhizae Radix with 106, Angelicae Gigantis Radix with 101, Alismatis Rhizoma with 95, Rhei Rhizoma with 90, Atractylodis Rhizoma Alba with 84, Rehmanniae Radix Preparata with 78, Leonuri Herba with 74, Moutan Cortex Radicis with 66, Aconiti Lateralis Preparata Radix with 66 Cnidii Rhizoma with 65, Pseudostellaria heterophylla with 62, Liriopis Tuber with 55, Lycii Fructus with 52, Rhei Rhizoma with 49, Codonopsis Pilosulae Radix with 44, Paeoniae Radix Rubra with 44, Schisandrae Fructus with 42, Polyporus with 42, Achyranthis Radix with 41 and Euryales Semen with 40. Medicines prescribed more than 30 grams a day included Astragali Radix, Imperatae Rhizoma, Benincasae Pericarpium, Leonuri Herba, Dioscoreae Rhizoma, Plantaginis Semen, Polyporus, Hoelen, Halloysitum Rubrum, Achyranthis Radix, Arecae Pericarpium, Phaseoli Angularis Semen, Coicis Semen, Rhei Rhizoma, Salviae Miltiorrhizae Radix, Sargassum, Ostreae Concha, Pseudostellaria heterophylla, Epimedii Herba, Rehmanniae Radix, Scrophulariae Radix and Polygonati Rhizoma. No scientific reports on the traditional medicinal aspects of diabetic nephropathy was searched. This analysis report would be able to provide the basis of developing new drug candidates for the treatment of diabetic nephropathy, as well as securing the EBM for the traditional medicines already being prescribed to the patients.

• 한국의사학회지
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• 제33권1호
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• pp.99-112
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• 2020

In this study, we examine the changes to Korean medicine that occurred when 'proprietary medicines' (賣藥) swept through the pharmaceutical market during the Japanese occupation (1910-1945 C.E.). Proprietary medicine during the Japanese colonial period took various forms including ready-made, over-the-counter, patent, and nostrum type pharmaceuticals. This paper examines how Korean medicine, which was the dominant form of medicine during the Joseon Dynasty, was forced to adapt to the rise of proprietary medicines. We found that the prescription of Korean medicine herbal decoctions became more like proprietary medicine in the way that they were formulated. In addition, prescriptions in Korean medicine books were reformulated with prescriptions and medicines from outside the tradition. Proprietary medicines, many of which were made with secret recipes handed down in a family, also attracted attention. Such prescriptions were made famous through advertisements and further influenced future Korean medicine doctors. New prescriptions took advantage of the trust and authority existing in traditional Korean medicine by introducing ginseng and traditional medicinal herbs such as deer antler velvet (鹿茸, Cervi Parvum Cornu). This paper argues that proprietary medicine of the Japanese colonial period distorted the concept of traditional herbal medicine.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2000년도 The 7th International Symposium
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• pp.84-95
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• 2000

Panax ginseng and the herbal medicinal mixtures containing ginseng have been widely used as a traditional medicinal prescriptions. In order to develop more efficient and protective prescriptions on seizures and subsequent memory deterioration, we investigated the biochemical and ethopharmacological effects of ginsenosides and fractions from the natural medicinal plant products related to control convulsions. In this studies we show results improving spatial teaming and memory deficits induced by kainic acid, a potent neurotoxic and neuroexcitatory analogue of the amino acid neurotransmitter glutamate.

• 대한한의학회지
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• 제19권1호
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• pp.220-233
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• 1998

This study was made to objectify the principle of oriental medical prescriptions so that we could obtain the principle and the formulation of them For that purpose, we analysed the formula and rule of 205 prescriptions recorded in Gum-goe-yo-rak, which have a few of components, and are widely used in clinical from ancient times to these days. At first we classified those prescriptions by their effect. Then we re-classified the herbs of the effect groups into four natures (cold, hot, warm and cool) and five kinds of flavors (sour, bitter, sweet, acrid and salty). And we classified the herbs into three grades - superior, medium, and inferior - which were used in Shen Nong's Herbal Classic. By these means, we statistically evaluated the prescriptions recorded in Gum-goe-yo-rak based on the Four Regular Components(Monarch, Minister, Assistant, and Laborer). As a result we could obtain some facts about the prescriptions recorded in Gum-goe-yo-rak, those are what kind of herbal material was used frequently and distribution of the natures flavors and grades according to thier effects. And we are sure that these results can be great help for establishment of fundamental formulation of theory of traditional herbal medicinal polyprescription.

• 한국식품과학회지
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• 제43권5호
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• pp.624-632
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• 2011

본 연구에서는 민간 및 한방에서 관절염 치료 처방제로 널리 사용되고 있는 한방처방제 16종을 선정하여 향후 관절염 예방 및 치료용 기능성식품의 개발 기초 자료로 활용하기 위해 한방처방제로부터 물, 에탄올 및 효소처리추출물을 제조하고 그들의 항산화 및 항염증활성을 in vitro assay system을 사용하여 측정하였다. 16종 한방처방제의 각 추출물의 폴리페놀 함량은 10.03-78.03 mg/g의 범위를 나타내었으며, 이 중 마행의감탕(7번)의 에탄올추출물이 78.03 mg/g으로 16종의 한방처방제 중 가장 높은 폴리페놀 함량을 보였다. 총 플라보노이드 함량의 경우 총 폴리페놀 함량의 결과와 달리 효소추출물에서는 폴리페놀 추출 함량이 낮아지거나 비슷한 수치를 보였지만 총 플라보노이드 함량의 경우 마행의감탕(7번)을 제외한 나머지 15종의 한방처방제에서 열수 및 에탄올추출물보다 효소추출물에서 플라보노이드 함량이 증가하는 것을 확인하였다. 한편, 마행의감탕(7번) 추출물에서 DPPH 및 ABTS 라디컬 포착활성과 COX-2 저해활성도 가장 높게 나타난 반면, 효소추출물에서는 의의인탕(14번)이 가장 높은 COX-2 저해활성을 나타내었다. 이러한 결과를 종합해 볼 때 마행의감탕 및 의의인탕을 관절염 치료 한방처방제로 개발할 가능성이 높다고 생각되며, 향후 보다 상세한 그들의 항산화 및 항염증활성을 조사할 필요가 있다고 생각된다.

• 대한예방한의학회지
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• 제23권1호
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• pp.49-59
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• 2019

Objective : We searched and collected the various ways of taking medicine in Naegyeong, Dongeuibogam and studied the possibilities to apply the traditional ways of taking medicine to the current way of taking medicine. Method : We collected all the ways of taking medicine in Naegyeong and classified the ways according to the relative importance, urgency, pathosis, time of disease, and, the conditions of patients. Result : Medicinal forms are decoction, pills, trituration, and thin porridge. Various kinds of water and the prepared rice forms were used. A single herb was boiled and its water was used to take the medicine. Also, liquor and honey were used to take medicine. More than two herbs or special prescriptions were boiled and the extract water was taken. The same medicine was taken by different boiled water according to the condition and age of a patient, time, acute or chronic illness, and, severe or mild disease. Conclusion : There are a lot of pills and trituration prescriptions in Naegyeong, Dongeuibogam. Water, various rice preparations, and several herbs are used to take these prescriptions. The reason is that these ways of taking medicine promote the medicinal effect and fast treatment to maximize the medicinal effects. From now on, the in-depth and mutilple studies are needed based on this research.