• Title/Summary/Keyword: traditional herbal medicine

Search Result 1,851, Processing Time 0.034 seconds

The improving effects of Saengmaeksan on ulcerative colitis

  • Kim, Min-Cheol;Kim, Su-Jin;Choi, In-Young;Ki, Ji-Ye;Kim, Dae-Seung;Jeon, Yong-Deok;Bae, Go-Eun;Choi, Sun-Kyung;Jeong, Hyun-Ja;Park, Yun-Jum;Kim, Hyung-Min;Um, Jae-Young;Hong, Seung-Heon
    • Advances in Traditional Medicine
    • /
    • v.10 no.2
    • /
    • pp.116-122
    • /
    • 2010
  • Saengmaeksan (SMS) is a well known Korean traditional herbal prescription, which consists of 3 different herbs, Radix Ophiopogonis, Radix Ginseng, and Fructus Schisandrae. SMS has been commonly used in various disease including respiratory system and cardiovascular System in Korea. The objective of this study is to find out the improving effects of SMS against Dextran Sulfate Sodium (DSS)-induced ulcerative colitis. SMS reduced clinical signs of DSS-induced colitis, including body weight loss, shorten colon length, and increased disease activity index. The results showed that SMS significantly inhibited the activation of nuclear factor-${\kappa}B$ p65 in the colon tissues of DSS-treated mice. In addition, we observed that result showed that the levels of IL-6 in plasma were increased in DSS treated group compared to those of the normal group, but these increased levels were reduced by administration with SMS. Taken together, these findings suggest that SMS has improving effects on DSS-induced ulcerative colitis, which may explain its beneficial effect in the regulation of chronic intestinal inflammation.

Black ginseng-enriched Chong-Myung-Tang extracts improve spatial learning behavior in rats and elicit anti-inflammatory effects in vitro

  • Saba, Evelyn;Jeong, Da-Hye;Roh, Seong-Soo;Kim, Seung-Hyung;Kim, Sung-Dae;Kim, Hyun-Kyoung;Rhee, Man-Hee
    • Journal of Ginseng Research
    • /
    • v.41 no.2
    • /
    • pp.151-158
    • /
    • 2017
  • Background: Chong-Myung-Tang (CMT) extract is widely used in Korea as a traditional herbal tonic for increasing memory capacity in high-school students and also for numerous body ailments since centuries. The use of CMT to improve the learning capacity has been attributed to various plant constituents, especially black ginseng, in it. Therefore, in this study, we have first investigated whether black ginseng-enriched CMT extracts affected spatial learning using the Morris water maze (MWM) test. Their molecular mechanism of action underlying improvement of learning and memory was examined in vitro. Methods: We used two types of black ginseng-enriched CMT extracts, designated as CM-1 and CM-2, and evaluated their efficacy in the MWM test for spatial learning behavior and their anti-inflammatory effects in BV2 microglial cells. Results: Our results show that both black ginseng-enriched CMT extracts improved the learning behavior in scopolamine-induced impairment in the water maze test. Moreover, these extracts also inhibited nitric oxide production in BV2 cells, with significant suppression of expression of proinflammatory cytokines, especially inducible nitric oxide synthase, cyclooxygenase-2, and $interleukin-1{\beta}$. The protein expression of mitogen-activated protein kinase and nuclear $factor-{\kappa}B$ pathway factors was also diminished by black ginseng-enriched CMT extracts, indicating that it not only improves the memory impairment, but also acts a potent anti-inflammatory agent for neuroinflammatory diseases. Conclusion: Our research for the first time provides the scientific evidence that consumption of black ginseng-enriched CMT extract as a brain tonic improves memory impairment. Thus, our study results can be taken as a reference for future neurobehavioral studies.

Experimental studies of Glycine max Merr. (black bean), Triticum aestivum L. (wheat) and Oryza sativa L. (rice bran) extracts on the effects of hair growth activity and physical properties (검은콩, 밀, 쌀겨 추출물이 모발의 성장과 물리적 특성에 미치는 효과)

  • Park, Hye-Yoon;Kim, Su-Na;Kang, Byung-Ha;Lee, John-Hwan
    • Korean Journal of Oriental Medicine
    • /
    • v.16 no.3
    • /
    • pp.167-173
    • /
    • 2010
  • Objects : Glycine max Merr. (black bean), Triticum aestivum L. (wheat) and Oryza sativa L. (rice bran) have been widely used for treatment of relaxion of smooth muscle, gastrointestinal hemorrhage and alopecia in Korean Traditional Medicine. In this research, we examined the effect of the extracts, obtained from EtOH extracts of 3 kinds of traditional plants, on hair growing activity of the DP6 and C3H10T1 cell and physical properties. Materials and Methods : On the basis of previous studies, three traditional plants were selected and we extracted them with ethanol. We evaluated their hairy dermal papillar cell proliferation activity and mouse mesenchymal stem cell in vitro model. Also, 3 herbal extracts were added to the normal shampoo formulation in ranges of 0.1% and we validated tensile properties and physical changes using aged hair. In this research, we compared the tensile strength, shine and color appearance between the hair (general formulation) and the hair after applying shampoo with natural extracts. To analyze the luster and color image, we use the SAMBA hardware and software made by Bossa Nova Technologies. Results : In the comparative test for tensile characteristic between the hair treated general formulation(control) and the hair applying special formulation including 3 kinds of extracts, tensile distance and energy of the latter are larger than control on average. The shine and color appearance were also increased after using shampoo including natural extracts(shine : 10.9%, color appearance: 24.12%). We observed the enhancement of hair growth activity in the DP6 and C3H10T1 cell. Especially black bean extracts had the most powerful effect in the dermal papillar cell proliferation. Conclusion : These experiments suggest that extracts of Glycine max Merr. (black bean), Triticum aestivum L. (wheat) and Oryza sativa L. (rice bran) stimulate the hair growth activity and can improve physical activities of aged hair. Shampoo product, which contains 3 kinds of natural extracts, would be used for the treatment for aged hair.

A comparison study of the effects of loratadine-pharmacopuncture and loratadine-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice

  • Kim, Hyun-Min;Kim, Hyun-Min;Lee, Min-Jung;Cho, Min-Gi;Kang, Deok;Kim, Yu-Kyung;Kim, Changmin;Kang, Do-Hyun;Jeong, Si-Hwa;Ahn, Ik-Gyun;Hwang, Jun-Hyeok;Kim, Jae-Hyun;Lee, Hyun-Jin;Jang, Jun-Yeong;Park, Ho-Jung;Kang, Sin woo;Youm, Jieun;Baek, Seung-won;Kim, Eu Jin;Shin, Moon-Kou;Park, Chan;Son, Chang-Bin;Yim, Tae-Bin;Lim, Jung Hyun;Hong, Sung-eun;Choi, Jun-Hyuk;Kim, Jun-Dong;Yoon, Dong-ju;Lee, Dong-Min;Yu, Soo-Min;Hong, Ye-Im;Lee, Yeong-Seok;Koo, Bon-Cheol;Park, Hyoung-Jun;Uem, Chae-Yoon;Kim, Min-Jeong;Oh, Jayoung;Park, NamGyeong;Kim, Eun-Jong;Cho, Whi-Sung;Lee, Ho-Sung;Kim, Tae-oh;Yoon, Cheol;Kwon, Sung-Keun;Jeong, Dong-Hyeon;Lee, Changwon;Yu, Sang-Yeol;Shon, Chae-won;Jeon, Gyu-Ri;Hong, Yang-Seok;Moon, Phil-Dong
    • CELLMED
    • /
    • v.8 no.1
    • /
    • pp.5.1-5.4
    • /
    • 2018
  • Pharmacopuncture, or herbal acupuncture, is a new form of therapy derived from combinations of two traditional therapeutic methods, herbal medicine and acupuncture therapy. To compare the efficacy between loratadine-pharmacopuncture (LP) and loratadine-oral administration (LO), the effect of loratadine was investigated in murine models. Anti-anaphylactic effects of loratadine treatments were investigated in compound 48/80-induced systemic anaphylactic reaction and passive cutaneous anaphylaxis (PCA). LP treatment significantly inhibited the compound 48/80-induced systemic anaphylactic reaction and PCA. The effect between LP and LO were on a similar level. These results indicate that LP can be used as an alternative method for LO in case of emergency.

Study on ${\ulcorner}Bonchojeonghwa{\lrcorner}$ ${\ulcorner}Inbu{\lrcorner}$ ("본초정화(本草精華)" "인부(人部)"에 대한 고찰)

  • Kwon, Young-Bae;Eom, Dong-Myung;Kim, Hong-Kyoon
    • Korean Journal of Oriental Medicine
    • /
    • v.11 no.2
    • /
    • pp.1-22
    • /
    • 2005
  • Study on ${\ulcorner}$Bonchojeonghwa${\lrcorner}$, which is one of the most specialized medical books in Boncho(Herbal Medicines), has been done by comparing it with some other medical books published in the Chosun dynasty. Though there was not meaningful result on e names of Korean medicine by this study and more study should follow in the future, from medicines recorded in ${\ulcorner}$Inbu (a chapter of medical ingredients from human body)${\lrcorner}$, we can reach on some results as follows by comparing in names of Korean medicines, their medical components, relevant explanations and etc. 1. Though it is difficult to know the author and the published year due to absence of the preface and epilogue, the publication is presumed to date from mid-l7th century, from the facts that Muheeong's ${\ulcorner}$Shinnongbonchokyongso${\lrcorner}$ is in the ${\ulcorner}$Bonchojeonghwa${\lrcorner}$'s reference list, and that there is not Hangul expression in the names of medicines nor the Ching dynasty’s books as a reference. 2. As a result of studying on the names of medicines recorded in ${\ulcorner}$Inbu${\lrcorner}$ of the Chosun dynasty's famous medical books, before ${\ulcorner}$ Bonchojeonghwa${\lrcorner}$, 19 medicines in ${\ulcorner}$Hyangyakjipsungbang${\lrcorner}$, 25 in ${\ulcorner}$Donguibogam${\lrcorner}$, and after ${\ulcorner}$Bonchojeonghwa${\lrcorner}$, 6 in ${\ulcorner}$Uimumbogam${\lrcorner}$, 4 in ${\ulcorner}$Kwangjebikup${\lrcorner}$, 11 in ${\ulcorner}$Bangyakhappyon${\lrcorner}$. And there are 37 medicines which are unique, ${\ulcorner}$Bonchojeonghwa${\lrcorner}$ has 31, the biggest records among them. 3. As a result of studying on the names of medicines recorded in 「Inbu」 of the ${\ulcorner}$Bonchojeonghwa${\lrcorner}$ and ${\ulcorner}$ Donguibogam${\lrcorner}$, 22 medicines were recorded in the both books, 9 were only recorded in ${\ulcorner}$Bonchojeonghwa${\lrcorner}$ and 3 were only recorded in ${\ulcorner}$Donguibogam${\lrcorner}$. 3 out of the total 37 medicines recorded in ${\ulcorner}$Inbu${\lrcorner}$ are only recorded in ${\ulcorner}$Hangyakjipsungbang${\lrcorner}$, and more study on this is needed. 4. From the contents recorded in ${\ulcorner}$Bonchojeonghwa${\lrcorner}$ and ${\ulcorner}$Donguibogam${\lrcorner}$, Benchojeonghwa is more in detail than Donguibogam. Thus, it was specialized in Boncho (Herbal Medicines) enough to be compared with general medical books, and played a good role in leading medical science's specialization. 5. Late Chosun dynasty's medical study on Boncho (Herbal Medicines) just like ${\ulcorner}$Bonchojeonghwa${\lrcorner}$ didn't lead to an active development of knowledge communication due to Confucian ethics. This limitation created the trend relying on general medical books or Yaksungga (songs of memorizing Boncho information) for Boncho information, but Boncho information of late Chosun dynasty became more in detail. That is, while Bokhapbang, combination of various medicines, were developed in China, Danmibang, single medicine but different intensity, were developed in Chosun. And thus, even though the kinds of medicines became smaller, but its contents became rather rich. 5. The medicines recorded in ${\ulcorner}$Bonchojeonghwa${\lrcorner}$ and ${\ulcorner}$Donguibogam${\lrcorner}$ are, from the view point of today, unclean or rather uncomfortable to use. Out those medicines, Bunchung, Hwasijangsanginkol, Hongyon, Gonidoogun, Inkondang had been used for a very long time and which proves their medical efficacy, and it is a great pity that they can’t be tried today due to the limitation by modern ethics.

  • PDF

Effects of Korean Medicine Treatment for a Patient with Lumbar Radiculopathy Diagnosed with Bertolotti's Syndrome: A Case Report (베르톨로티 증후군으로 확인된 요추 신경병증 환자에 대한 한의학적 치료 효과: 증례보고)

  • Han, Jeonghun;Park, Byunghak;Son, Jaemin;Lee, Namwoo;Kang, Dohyeon;Min, Taewoon;Ahn, Jaeseo;Lee, Hansol;Lee, Hyunjun;Ji, Hyungwook;Cho, Sohyun;Lee, Seongmin;Kim, Hankyul
    • Journal of Korean Medicine Rehabilitation
    • /
    • v.31 no.4
    • /
    • pp.203-210
    • /
    • 2021
  • Bertolotti's syndrome is a rare spinal disease and it is known to cause low back pain due to a lumbosacral transitional vertebra. There has been rare study of Bertolotti's syndrome. This study reports the effects of Korean medicine treatment on the patient who was diagnosed on Bertolotti's syndrome. The patient was treated with Korean medicine treatment including acupuncture, pharmacopuncture, herbal medicine, and Chuna manual therapy during 40 days. Numerical rating scale (NRS), Euroqol five dimension (EQ-5D) index, Oswestry disability index (ODI), lumbar range of motion were used for assessment. After treatment, low back pain NRS decreased from 3 to 2, and low limb pain NRS decreased from 5 to 2. EQ-5D index, ODI and lumbar range of motion also were improved. This study shows Korean medicine treatment can be an effective care for Bertolotti's syndrome.

Effects of Korean Medicine Treatment Including Motion-Style-Acupuncture-Treatment for a Gait Disorder Patient with Myelin Oligodendrocyte Glycoprotein-Associated Disorder: A Case Report (Myelin Oligodendrocyte Glycoprotein-Associated Disorder로 진단받은 보행장애 환자에 대한 Motion-Style-Acupuncture-Treatment 요법을 포함한 한의학적 치료 효과: 증례보고)

  • Hyungwook Ji;Hankyul Kim;Seongmin Lee;Hansol Lee;Sohyun Cho;Ilhwan Ko;Jiwon Kim;Jungmin Yun;Hyukjin Jeong;Siwon Kim;Seeyoung Park;Hwangwoo Seok;Junha Jeon
    • Journal of Korean Medicine Rehabilitation
    • /
    • v.33 no.4
    • /
    • pp.215-223
    • /
    • 2023
  • The purpose of this study is to report the effects of Korean medicine treatment on the gait disorder. Patient with myelin oligodendrocyte glycoprotein-associated disorder. We treated the patient using Korean medicine treatment including Motion-Style-Acupuncture-Treatment, pharmacopuncture, acupuncture, and herbal medicine during 30 days. Numerical rating scale (NRS), EuroQol five dimension (EQ-5D) index, Oswestry Disability Index (ODI), Modified Barthel Index (MBI), and the changes of symptoms were measured for assessment. After 30 days inpatient treatment, NRS decreased from 4 to 2, EQ-5D index, ODI, MBI, and the symptoms of the patient also were improved. In conclusion, this case shows Korean medicine treatment might be an effective treatment for gait disorder Patient with MOG-associated disorder.

Pharmacognostical Studies on the Folk Medicine "SaCheolNaMu" (민간약 사철나무의 생약학적 연구)

  • Park, Woo Sung;Chung, Hye-Jin;Bae, Ji-Yeong;Park, Jong Hee;Ahn, Mi-Jeong
    • Korean Journal of Pharmacognosy
    • /
    • v.44 no.4
    • /
    • pp.320-325
    • /
    • 2013
  • "SaCheolNaMu" has been used as a Korean folk medicine for the jaundice, lumbago and uterine diseases. Although a crude drug related to this folk medicine is sold in traditional herbal market, the botanical origin of this drug has not been pharmacognostically confirmed yet. In this study, the morphological and anatomical characteristics of the stem of Euonymus species growing in Korea, i.e. Euonymus japonica and E. fortunei var. radicans were studied to clarify the botanical origin of "SaCheolNaMu". As a result, it was found that these two species could be discriminated by the morphological criteria such as the thickness of cuticles, the number of collenchyma cell layers, and the frequency of druse and resinous substance. According to these criteria, it was elucidated that the commercial folk medicine "SaCheolNaMu" was the stem of E. japonica. Meanwhile, HPLC-DAD analysis on the 70% ethanolic extracts of two species showed significantly different HPLC profiles each other. The molecular ions of three characteristic peaks shown in the chromatogram of two species were identified by ESI-MS, and their structures were estimated to be flavonol glycosides.

Antiosteoporotic Effects of Polygoni Multiflori Radix (PMR) in Ovariectomized (OVX)-Induced Osteoporosis ddY Mice (하수오 물 추출물이 마우스 골다공증에 미치는 영향)

  • Do, Yoon-Jung;Ku, Sae-Kwang;Kim, Hong-Tae;Oh, Tae-Ho;Cho, Young-Moo;Kim, Sung-Woo;Ryu, Il-Sun;Lee, Keun-Woo
    • Journal of Veterinary Clinics
    • /
    • v.28 no.4
    • /
    • pp.375-386
    • /
    • 2011
  • Polygoni Multiflori Radix (PMR), a dried root tuber of Polygonum multiflorum Thunberg with bioactivities in bone metabolism is one of the most famous tonic traditional medicines. To observe in vivo anti-osteoporotic efficacy of PMR extracts, we orally administered once a day for 28 days (Qd ${\times}$ 28) to bilateral ovariectomized (OVX)-induced osteoporosis ddY mice after 1 week of recovery periods at 125, 250 and 500 mg/kg (of body weight). A positive control drug, Alendronate (FOSA) 10 mg/kg-dosing group was added. As results of OVX-induced osteoporotic process, estrogen-deficient osteoporotic changes were also dramatically decreased in all PMR extracts-dosing groups. Especially middle dosage of PMR extracts, 250 mg/kg constantly and significantly (p < 0.01 or p < 0.05) inhibited the loss of bone strength and bone quality. Based on the results, it was concluded that PMR extracts (125, 250 or 500 mg/kg; orally dosing) has relatively good favorable effect to prevention and/or treatment of OVX-induced osteoporosis. Therefore, although the efficacy was slighter than that of Alendronate on the inhibition of bone loss, it is expected that PMR extracts will be promising as a new anti-osteoporotic agents for prevent the fracture induced in osteoporotic patients because natural herbal medicine origin PMR extracts will be dose not show serious side effects especially the problem in upper alimentary irritation by bisphosphonate and hypercalcaemia of parathyroid hormone analogs.

A study on Jang Cong-zheng's treatment in "Ru-Men-Shi-Qin" ("유문사친(儒門事親)"에 나타난 장종정(張從正)의 치료법(治療法)에 관(關)한 연구(硏究))

  • Kim, Yong-Hwan;Lee, Sang-Hyup;Kim, Joong-Han
    • Journal of Korean Medical classics
    • /
    • v.25 no.3
    • /
    • pp.127-147
    • /
    • 2012
  • Objective : Methods of Jang Cong-zheng's treatment related to his theories include of promoting the sweating-vomiting-purgation(汗吐下三法), prickling-bleeding method(瀉血療法), and emotional therapy(情志療法). He succeeded Liu wan-su(劉完素) as promoter of fire-heat pattern theory(火熱論), thereby emphasizing six qi(六氣), especially fire(火) and dampness(濕), as pathogens. He suggested that physician should treat patients whose diseases occurred due to fire(火) and dampness(濕) with promoting the sweating(汗)-vomiting(吐)-purgation(下) methods, which would remove pathogen qi(邪氣) and help circulation of qi and blood, therefore getting them back healthy qi(正氣). Method : I will try to describe the Jang Cong-zheng's treatment in "Ru-Men-Shi-Qin", and I would like to explain the sweating-vomiting-purgation(汗吐下三法), prickling-bleeding method(瀉血療法), and emotional therapy(情志療法). Result : For emotional diseases, he suggested that most should be caused by heart fire(心火) so they should be treated with methods of suppressing heart fire and medication would be using cool and cold herbal drugs which lead to clear heart fire. Conclusion : Theories of Zhang zi-he(張子和) can be applied to nurturing for modern world maintaining and improving health by his care methods. People these days suffer usually from excess intake or unbalanced diet problem, so wastes matter and pathogenic qi can be driven out of the human body by applying the sweating-vomiting-purgation methods. His medical theories could contribute to modernization of traditional medicine this way.