• Biomedical Science Letters
• /
• v.17 no.4
• /
• pp.283-289
• /
• 2011

Our previous study demonstrated that the Korean traditional medicine Gyeongshingangjeehwan (GGEx) activates AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor ${\alpha}$ ($PPAR{\alpha}$) critical for fatty acid oxidation in skeletal muscle and C2C12 skeletal muscle cells. Thus, we examined whether GGEx can reduce lipid accumulation in these cells and tissues. After obese and type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats were treated with GGEx, we studied the effects of GGEx on skeletal muscle lipid accumulation. The effects of GGEx and/or the AMPK inhibitor compound C on lipid accumulation and expression of AMPK and $PPAR{\alpha}$ were measured in C2C12 skeletal muscle cells. Compared with lean Long-Evans Tokushima Otsuka rats, obese OLETF rats had increased triglyceride droplets. However, administration of GGEx to OLETF rats for 8 weeks significantly decreased triglyceride droplets in skeletal muscle. Consistent with the $in$ $vivo$ data, GGEx inhibited lipid accumulation, the degree of which was comparable to Wy14,643, the potent activator of $PPAR{\alpha}$. GGEx also increased skeletal muscle mRNA levels of AMPK${\alpha}1$, AMPK${\alpha}2$, and $PPAR{\alpha}$. However, compound C inhibited these effects in C2C12 cells. These results suggest that GGEx suppresses skeletal muscle lipid accumulation and this process may be mediated by AMPK and $PPAR{\alpha}$ activation.

• Journal of the Korea Fashion and Costume Design Association
• /
• v.6 no.1
• /
• pp.25-33
• /
• 2004

This study is aimed at reviewing how the Orientalism trend is expressed in the modem fashion in terms of silhouette, color, materials, and detail. To this end, the geographic scope of this study is limited to China, Japan, Korea, while data are collected from fashion collections, domestic and foreign magazines since 2000's, literature, and internet sites. The results of this study can be summarized as follows: 1. Silhouette: the basic square silhouette of the Oriental traditional costume do not disturb the body movement and have an effected on design to smoothly follow the body line rather than cutting out materials into several parts or emphasize the curved body. 2. Color: due to the influence of the Oriental Zen thought, color trend seems to pursue simplicity rather than complexity, and natural aesthetics. In addition, the Oriental colorfulness shall not be ignored. 3. Materials: golden embroidered material, polished satin, jersey, tough or rough materials, etc. have used with materials of the Oriental traditional costume came into fashion. In pattern, the Orientalism trend is expressive of pattern by Chinese ink-spread technique, simple brush touch technique, cloud pattern, lotus flower pattern or dragon pattern, all of which feature the Oriental calm aesthetics or those motivated by the Oriental traditional patterns. 4. Detail: the techniques of handicrafts and manual arts such as meticulous embroidery, tassel or patchwork reflect well the Orientalism trend in the modem fashion.

• Architectural research
• /
• v.17 no.2
• /
• pp.49-56
• /
• 2015

For more than 100 years, American skyscrapers got along with the change of Modern architecture. However, high-rise building can not be regarded anymore as a monopoly of America. The purpose of this study is to clarify the aesthetic characteristics of Asian high-rise buildings. Basic concepts on the aesthetic and artistic expression of high-rise building have been discussed, emphasizing the importance of artistic characteristic. A brief introduction on the rise of Asian high-rise buildings also summarized in terms of changing trends for decades from 1970s. Among the 75 buildings in Asian countries out of 100 tallest buildings in the world, 10 buildings are selected to clarify the artistic characteristics which can be presented as an Asian trend in 21st century. The results can be summarized as follows; It was from 1990s that the Asian high-rise buildings began to express a specific regional aesthetics as a trend of post-modernism. Conventional ideas, traditional objects, and regional shapes and patterns are good instruments to successfully represent their national prides. Religions in Chinese and Islamic culture are popular motifs in Asian countries as well as feng shui and conventional idea of five primary elements. Traditional objects like pagoda and minaret are good precedents that can provide friendly recognized vertical objects. Many other interesting cases can be found referring to the traditional shapes and patterns like Chinese character, geometric pattern, Islamic sign, etc.

• Journal of the Korean Society of Costume
• /
• v.47
• /
• pp.143-160
• /
• 1999

The purpose of this dissertation is to interpret fashion through a socio-cultural phenomenon called kitsch by understanding its aesthetic characteristics and clarifying its significance in the modern consumer society and analyzing the examples of kitsch appearing in modern fashion. The following are the arguments and conclusion of this dissertation. First kitsch has negative meanings such as aesthetic inadequacy or bad tastes implying vulgar popular tastes of faked sensations just imitating elite culture and using things indiscriminately for inferior reproduction or at best the philosophical and aesthetic category that expresses the mass of people's attitudes toward life in accepting the consumer culture of the industrial society. It started from the art of romanticism accompanied by th commercializing of art with the bourgeois society background formed in the mid-19th century. Though kitsch started to prevail following the socio-cultural changes caused by the Industrial Revolution in the 19th century it is only in the late 20th century that kitsch has come tc our everyday life and has become an object of aesthetic arguments. Second formative characteristics of kitsch appearin in fashion have a cumulative inadequate romantic pleasure-seeking satirizing and multicomplex nature. Third the socio-cultural meanings of kitsch appearing in fashion are as follows: The extension of commercialism which gratifies the pleasure-seeking mass consumers the enlargement of the aesthetic category by inclining to everyday commonplace aesthetic sense the expression of one's identity through the gratification of desire and the new aesthetics of resistance and deviance by an anti-traditional and anti-elite tendency towards the traditional society and aesthetic values.

• Journal of the Korean Society of Costume
• /
• v.56 no.6 s.105
• /
• pp.87-95
• /
• 2006

This is a study regarding the development of Cultural Products with Applied Koguryo Wadang Patterns. The objective of this study is in developing unique Cultural Products which combine traditional Korean images with modern feel by utilizing Koguryo Wadang patterns. The among Korean traditional patterns which implicit the sense of beauty and modeling, chose and investigated the Wadang patterns of the Koguryo. And from it, studied about the originality and characteristics of the Koguryo Wadang patterns. In this characteristics of the Wadang pattern, the representative lotus design pattern was based and reorganized to fine the probability of the modern expression using traditional patterns. After design plans were made for each works, natural dyes were used to dye(dip dyeing, printing) the fabrics(cotton:Kwang-mok) by theme. Approximately 16 pieces of Cultural Products that can be used in daily life were created using Koguryo Wadang patterns, including Traffic or credit card cases, Name card cases, Pouches, CD cases, Cushions, Bags, Purses, Vest, Muffler. In addition, the increased quality of the products will be a competitive edge in the world market where products compete with no national bounds.

• Journal of Life Science
• /
• v.23 no.3
• /
• pp.383-388
• /
• 2013

This study was performed to determine the whitening effect of several solvent fractions of Diospyros kaki extracts. Fractions from ethanol extracts of D. kaki were prepared by a systematic fractionation procedure using hexane, ethyl acetate, butanol, and $H_2O$. The ethyl acetate fractions were used to evaluate the inhibitory effects on tyrosinase activity and melanin synthesis in B16F10 melanoma cells. Ethyl acetate fractions suppressed the expression of tyrosinase, TRP-1 and TRP-2 in B16F10 melanoma cells. These results showed that ethyl acetate fractions of D. kaki could be developed as a skin whitening material in cosmetics.

• Journal of Applied Biological Chemistry
• /
• v.59 no.4
• /
• pp.317-322
• /
• 2016

UV exposure induces matrix metalloproteinases (MMPs) and extracellular matrix-degrading enzymes expression. We studied the protective effect of Rubus occidentalis seed against UVB-generated skin photoaging using human fibroblast cells (CCD-986sk). We used an ELISA kit to measure the supernatents of procollagen type I and MMP-1 in CCD-986sk cells after they were exposed to UVB irradiation. The CCD-986sk cells that were used with RC-E/E after the UVB irradiation caused higher levels of type I procollagen and lesser levels of MMP-1 compared with the control group. Furthermore, the RC-E/E treated group showed lesser MMP-1 levels and higher procollagen type I levels than the untreated counterpart. Therefore, it can be concluded that Rubus occidentalis seed can prevent from skin photoaging.

• Fashion & Textile Research Journal
• /
• v.12 no.3
• /
• pp.257-264
• /
• 2010

In the modern Society, the human's way of thinking as well as the new cultural creation has been changing by bringing on a change rapidly. The moderns are demanding humanity and the new cultural cretion through the exchange between the old things and new things by setting material before everything else. The latest trends of today had an effect on the fashion Illustration, a new art category, which gives a new image. This report of research has a purpose which expresses korean images by connecting the korean tradition style to the modern fashion. And we are concerned about the national culture and tradition with the international stream. For this reason I studied these for the purpose of expanding expression area of sewing techniques by applying to fashion Illustration expressing handcraft techniques by natural beauty improving the modern and traditional images, updating, and succeeding to tradition. As the way of studying and contents, I referred to the inside and outside of the country's literatures, these, publications, magazines, or the internet sufing. Firstly, as the theoretical study, I studied a conception and history of the fashion Illustration. I studied the theoretical background of the sewing techniques through the histories, tools, and techniques. The theoretical background of the sewing handicraft is studied through the colors, patterns, materials and sorts. I also and indicated the various works by the domestic designers.

• The Journal of Korean Medicine
• /
• v.39 no.4
• /
• pp.126-135
• /
• 2018

Objectives: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and irreversible airflow. This study aimed to evaluate the effects of GHX02 in a COPD-induced mouse model. Methods: The COPD mouse model was established by exposure to cigarette smoke extract and lipopolysaccharide which were administered by intratracheal injection three times with a 7 day interval. GHX02 (100, 200, 400 mg/kg) and all other drugs were orally administrated for 14 days from Day 7 to Day 21. Results: GHX02 significantly decreased the neutrophil counts in bronchoalveolar lavage fluid (BALF) and the number of $CD4^+$, $CD8^+$, $CD69^+$, and $CD11b^+/GR1^+$ cells in BALF and lung cells. GHX02 also suppressed the secretion of tumor necrosis factor-alpha ($TNF-{\alpha}$), interleukin-17A, macrophage inflammatory protein 2 (MIP2), and chemokine (C-X-C motif) ligand 1 (CXCL-1) in BALF and ameliorated the lung pathological changes. Conclusions: Thus, GHX02 effectively inhibited airway inflammation by inhibiting migration of inflammatory cells and expression of pro-inflammatory cytokines. Therefore, GHX02 may be a promising therapeutic agent for COPD.

• The Journal of Asian Finance, Economics and Business
• /
• v.8 no.3
• /
• pp.1035-1044
• /
• 2021

Corporate longevity is an interesting issue from a theoretical point of view. In today's uncertain economic climate, the first priority for a company is survival. The longevity of an organization is basically one of the areas that can classify the sustainability of a company. Known as the cultural heritage of Indonesia, the traditional herbal medicine industry faces challenges of longevity. The word Jamu is a generic expression for traditional herbal medicine in Indonesia. The Jamu industry as Indonesia's cultural heritage must be preserved with good support from a technical, regulatory, and commercial perspective so that Jamu companies do not go into the decline stage. Operational resilience is usually defined as the ability of an organization to adapt rapidly to changing environments. This study aims to identify the effect of operational resilience and human capital on corporate sustainable longevity through innovation performance. The questions are addressed through empirical research of 108 small companies that produce Jamu, traditional herbal medicine in Java, Indonesia. This study was conducted during July-September 2020. Data analysis is carried out with SEM-PLS using SmartPLS software version 3.0 to evaluate the data collected. The results indicated that operational resilience influences corporate sustainable longevity directly and indirectly through innovation performance. However, human capital could not play the antecedent role to corporate sustainable longevity directly or even indirectly through innovation performance. Human capital indicators require deeper exposure in the context of small industries.