• 제목/요약/키워드: toxic substance

검색결과 233건 처리시간 0.031초

고압 독성가스 사고발생 시나리오별 안전거리 확보에 관한 연구 (A Study on the Safety Distances for High Pressure-toxic Gases by Specific Accident Scenarios)

  • 김송이;황용우;이익모;문진영
    • 한국가스학회지
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    • 제20권6호
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    • pp.1-8
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    • 2016
  • 2012년 구미 불화수소 누출사고 이후 화학 물질 사고에 대한 사회적 불안감이 증폭되었고, 이러한 불안감 해소를 위해 2015년부터 장외영향평가제도가 도입되었다. 장외영향평가제도는 대부분의 화학물질을 대상으로 하며, 반도체, 디스플레이, 태양광 산업 등 첨단산업 분야에서 주로 사용되는 대부분의 고압 독성가스가 이에 포함된다. 우리나라 기업들이 첨단산업 분야에서 높은 경쟁력을 보유한 만큼, 국내에서 고압 독성가스 사용량은 지속적으로 증가하고 있으며 이에 따라 사고발생 가능성도 높아질 것으로 예상된다. 이러한 상황에 따라 본 연구에서는 국내에서 사용되는 고압 독성가스 중 제조량 및 사용량이 높은 물질을 대상으로 미국 환경보호청과 미국 해양대기국이 공동 개발한 ALOHA 프로그램을 활용하여 사고영향범위를 평가하였으며, 알진의 사고영향범위가 4,700 m로 가장 넓은 것으로 나타났다. 사고영향범위 결과는 고압 독성가스 누출 시 효과적인 안전거리 결정에 활용할 수 있을 것으로 기대한다.

화학사고 유발 사고대비물질 관리 개선 방안 (Improvement Strategy for Management of Accident Preparedness Substances Causing Chemical Accidents)

  • 이덕재;류시완;송창근
    • 한국안전학회지
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    • 제32권1호
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    • pp.47-52
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    • 2017
  • Chemical accidents occur by a variety of causes and aspects. Accident preparedness substances (APS) are defined by toxic chemicals highly likely to cause accidents due to their high acute toxicity, explosiveness or likely to cause severe damage where a chemical accident occurs among the chemicals. APS is designated and announced by Presidential Decree. However, chemical accidents occurred for recent 7 years were arisen mainly from non-accident preparedness substances, and only 24 species were included as chemical accident trigger among total 69 APS. In addition, APS were designated in 2014 and the list has not been updated since then although it needs to be amended in several aspects. Accordingly, this study analyzes the necessity of modification of APS management, and presents improved plans.

흰쥐에 있어서 Fthalide의 독성 (The Toxicity of Fthalide in Rats)

  • 김영찬;장영수
    • 약학회지
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    • 제39권4호
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    • pp.450-460
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    • 1995
  • The acute toxicity of fthalide in rat was studied in vivo by the observations of the changes in hematogram, serological parameters, content of cytochrome p-450, activities of NADPH-cytochrom c reductase, glucose-6-phosphatase, and the contents of cholinesterase and carboxylesterase in liver. Fthabde is a practically non-toxic substance(LD50 is 3.86g/kg), but rats were intoxicated with fthabde at a oral dose of 100 mg/kg for 12 days. WBC were significantly decreased and activities of ALT and LDH, on the cotrary, the content of glucose in serum were slightly increased. Cytochrome p-450 and lipid peroxide in liver were significantly increased in the fthalide-intoxicated rats. The longer administration of fthalide showed further increase of carboxylesterase activity in liver and serum, but decrease of activities of glucose-6-phosphatase and cholinesterase in liver and serum. These results show that fthatide can induce the hepatocellular injury and neurotoxicity.

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A MATHEMATICAL MODEL OF A PREY-PREDATOR TYPE FISHERY IN THE PRESENCE OF TOXICITY WITH FUZZY OPTIMAL HARVESTING

  • PAL, D.;MAHAPATRA, G.S.;MAHATO, S.K.;SAMANTA, G.P.
    • Journal of applied mathematics & informatics
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    • 제38권1_2호
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    • pp.13-36
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    • 2020
  • In this paper, we have presented a multispecies prey-predator harvesting system based on Lotka-Voltera model with two competing species which are affected not only by harvesting but also by the presence of a predator, the third species. We also assume that the two competing fish species releases a toxic substance to each other. We derive the condition for global stability of the system using a suitable Lyapunov function. The possibility of existence of bionomic equilibrium is considered. The optimal harvest policy is studied and the solution is derived under imprecise inflation in fuzzy environment using Pontryagin's maximal principle. Finally some numerical examples are discussed to illustrate the model.

PERI-NATAL AND POST-NATAL STUDY OF THE RECOMBINANT HUMAN INTERFERON ${\alpha}A\;(rHuIFN-{\alpha}A)$ IN RATS

  • Lee, Yong-Soon;Kim, Yun-Bae;Kim, Hyun-Su;Cho, Nam-Jin;Yoo, Moo-Young
    • Toxicological Research
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    • 제3권1호
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    • pp.55-63
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    • 1987
  • A Peri-and Postnatal Study was Carried out to examine the effects of rHuIFN-${\alpha}A$, produced by gene-manipulated E. coli, on offsprings of Wistar rats. The substance was administered intraperitoneally to dams at dose levels of $1{\times}10^5$, $4{\times}10^5$ and $1.2{\times}10^6$ I.U/kg/day during the period from day 17 of gestation to day 21 after delivery. All the pregnant dams were allowed to deliver naturally, and the postnatal development of the offsprings was observed. No noticeable toxic effects and pathological changes on dams were observed, and no detectable variations in postnatal development of offsprings occured.

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창의적 문제 해결이론 (TRIZ, 트리즈)를 이용한 공기 정화 기능의 모기 유인 퇴치기 개발 (Development of Mosquito Trap with Effect of Air Cleaning by Using Theory of lnventive Problem Solving (TRIZ))

  • 이경원
    • 한국정밀공학회지
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    • 제19권6호
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    • pp.155-159
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    • 2002
  • This paper describes the development process of mosquito trap with the effect of air cleaning by using the substance-field analysis and evolution pattern of systems in the theory of inventive problem solving (TRIZ). We g(It the concept of the mosquito trap with mosquito attractants instead of mosquito reluctants such as mosquito stick coil and skin medicine with bad and toxic smell. The number of mosquitos traped by one trap near cattle shed per one night in summer, was over 10 thousands with some effects of air cleaning

유산동에 대한 Saccharomyce cerevisiae의 저항성에 관한 연구 (A study on the resistance of saccharomyces cerevisiae to copper sulfate)

  • 이민재;이진기
    • 약학회지
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    • 제3권1호
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    • pp.15-20
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    • 1957
  • Resume 1. The toxic effect of $CuSO_4$ on the growth of yeast began in the 0.2mM and colony formation was completely inhibited in the 3mM $CuSO_4$ media. 2. The yeast strain which was trained sucessively from lower concentration media to higher one, could grow even in 10mM $CuSO_4$ media. 3. Rlb strain produced brown pigment in copper media. 4. Resistance of Rlb strain to $CuSO_4$ did not revert in non copper media. 5. The appearance of resistant strain was regarded as the result of "Mutation and Selection". 6. The alcohol fermentation ability of Rlb strain was lower than that of parent strain. 7. Rlb strain yielded some effective substance which induced the parent strain to resist against $CuSO_4$. 8. The dehydrogenase activity of yeast was inhibited by $CuSO_4$.

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농촌주택 유형분석을 통한 재생우선순위 도출 (Selection of Priority for Revitalization by Analyzing Rural House Type)

  • 박길범;박준모;김옥규;방세라
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2014년도 춘계 학술논문 발표대회
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    • pp.174-175
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    • 2014
  • A Rural house in Chungcheong area have been variety of matters, rapid deterioration of house and incomplete of maintenance control, that is represented lack of durability heating from lack of heat insulation property, health worsening form use of toxic substance and so on. For farmers who did not know where to repair and how to repair, they are urgently needed measures of standard and basis that is to realize a condition of rural house. Accordingly, this study drew major matters and priority for revitalization through analysis of type of rural house from research on the actual condition in order to develope of diagnostic criteria of rural house.

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Treatment of Waste Dry Etching Gas in Semiconductors Manufacturing Process

  • Yamamoto, Hideki;Kawahara, Takahiro;Shibata, Junji
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2001년도 The 6th International Symposium of East Asian Resources Recycling Technology
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    • pp.711-714
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    • 2001
  • A new technology to make fluoride gas such as NF$_3$contained in the exhaust gas from semiconductor manufacturing plants convert directly into a harmless substance have been established and new concept on the disposal treatment of global warming gases were presented. Experimental results verify that the chemical reactions can be take place at substantially lower temperature of 80-40$0^{\circ}C$ as compared with the combustion treatment method. Reaction product is mainly metal fluoride which is a harmless and a valuable chemical material as one of new resources. The other favorable characteristics are that the continuous treatment is possible at a low temperature under atmospheric pressure. Furthermore this process is compact, easily controllable and safely operable at low running cost. This paper concerns with a new harmless disposal treatment of toxic global warming gas.

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염소처리에 의한 Microcystin의 제거 (Removal of microcystin by chlorination)

  • 이태관;진정숙
    • 한국물환경학회지
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    • 제18권3호
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    • pp.321-326
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    • 2002
  • On this study, removal method for microcystin, toxic substance released from the blue-green algae, using chloride was investigated. 82 ~ 98% of Microsystin were removed within 1 hr when sample had microsystin only. However, if the sample had algae cell removal efficiency was decreased to 50%, except the concentration of chloride $10Cl-mg/{\ell}$. As a result, intermediate-chlorination which dose chloride after coagulation process is considered the optimum method for the removal of microcystin because most of algae cell could remove during the coagulation process.