• Title/Summary/Keyword: total responses

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$HgCl_2$ Dysregulates the Immune Response of Balb/c Mice (수은에 의한 마우스의 면역반응 조절장애)

  • Ki, No-Suk;Koh, Dai-Ha;Kim, Chong-Suh;Lee, Jung-Sang;Kim, Nam-Song;Lee, Hwang-Ho
    • Journal of Preventive Medicine and Public Health
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    • v.27 no.1 s.45
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    • pp.11-24
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    • 1994
  • The studies reported here were undertaken to investigate the effects of mercury chloride on immune system of Balb/c mouse employing a flexible tier of in vitro and in vivo assays. Mercury chloride inhibited the proliferative responses of spleen cells to lipopolysaccharide, pokeweed mitogen, and phytohemagglutinin as a dose-dependent manner. This inhibitory effect was observed not only when $HgCl_2$ was added 2nd or 3rd day of 3 days culture period but also when spleen cells was pretreated with $HgCl_2$ for 2 hours. Mercury chloride, however, potentiated the production of IgM and IgG from spleen cells. During the $HgCl_2$ administration by drinking for 3 weeks, the weight gain of mice was significantly blunted than that o control group mice, while no overt signs related to mercury toxicity were noted in any mice of experimental group. There was no change in thymus and spleen weights, and in histological findings of kidney, bone marrow of femur, thymus, spleen, and popliteal lymph node after 3 weeks of mercury exposure. However, $HgCl_2$ induced a significant increase of total serum IgM, IgG including $IgG_1,\;IgG_{2a}\;and\;IgG_{2b}$, and IgE in Balb/c mice. Treatment in vivo with anti-IL-4 monoclonal antibody significantly abrogated the $HgCl_2$-induced increase in total serum IgG1 and IgE. Whereas $HgCl_2$ potentiated total serum IgM and IgG, there was no difference in total serum hemagglutinin to SRBC (Sheep Red Blood Cell) between experimental and control group mice when these mice were immunized with SRBC. All these findings observed in Balb/c mice suggest that mercury perturbates well-orchestrated regulation of immune responses before developing histopathological changes in lymphoid tissues.

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Evaluation of a Career Ladder Program for Nurses in a Hospital (임상간호사 경력개발 프로그램 평가)

  • Park, Kwang-Ok;Park, Sung Hee;Kim, Yeon-Hee;Choi, Jeong-Hee
    • Perspectives in Nursing Science
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    • v.11 no.2
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    • pp.123-131
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    • 2014
  • Purpose: The purposes of this study were to assess the efficacy and usefulness of the career ladder program in a hospital and to evaluate nurses' satisfaction with the program. Methods: The study was conducted using a survey consisting of 14 questions on the appropriateness, necessity and usefulness of the career ladder program. The data were gathered from 403 nurses in a hospital. We assessed differences in responses according to the participants' workplace, age, educational background, marital status, experience (total years and years at current working place). We analyzed the data using SPSS/WIN 12.0. Results: Nurses acknowledged that the career ladder program is necessary and profitable within the nursing field, but they worried about the appropriateness of the nurse's role at each career level and rationality of the portfolio. The study also identified nurses' characteristics that were significant factors in explaining nurses' satisfaction with the career ladder program. Finally, we identified complaints and improvements for the program. Conclusion: We assessed differences in attitude towards the career ladder program according to nurses' characteristics.

Peripheral Intravenous Injection Pain in Hospitalized Children (입원 아동의 말초정맥 주사시 통증 반응)

  • Jeong, Jun Hee;Ahn, Hye Young
    • Perspectives in Nursing Science
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    • v.11 no.2
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    • pp.144-152
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    • 2014
  • Purpose: The purpose of the study is to offer necessary data to develop nursing interventions to reduce intravenous injection pain and uneasiness among hospitalized children. Methods: A total of 200 patients aged 1-72 months were selected. Pain during intravenous cannulation was assessed using the Procedural Behavior Checklist (PBCL) and the Faces Pain Rating Scale (FPRS). Data were analyzed by t-test and ANOVA using the SPSS/WIN 12.0. Results: Younger patients showed higher pain response than older patients (F=33.87, p<.001). Children with respiratory diseases showed higher responses in FPRS and PBCL than children without respiratory disease (F=4.17, p=.017; F=25.31, p<.001, respectively). Children of preschool age showed higher pain response during IV cannulation than the comparison group (t=2.04, p=.045). Children who had previous experiences with hospitalization and injections showed higher response to pain than those without these experiences (t=2.05, p=.045). In regards to FPRS, patients who were recannulated showed more painful restarts compared with patients injected just once (t=-3.60, p<.001). In regards to PBCL, infants and toddlers (t=-4.88, p<.001) and preschoolers (t=-3.86, p<.001) showed high pain scores during recannulation. Conclusion: A sick child's response to pain may be worse as they feel more pain over time. These characteristics should be considered for development of nursing interventions.

The Clinical Observation of Immune Response by Korean Bee Venom Therapy (봉약침요법의 면역반응에 관한 임상적 연구)

  • Kwon, Gi-Rok;Koh, Hyung-Kyun
    • Journal of Acupuncture Research
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    • v.17 no.1
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    • pp.169-174
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    • 2000
  • The immune response of Bee Venom Therapy is commonly appear in clinics. It is whole body delayed allergy type and generally like fatigue. Therefore, in order to analysis the clinical form, we have observed immune response of 100 patients who visited Sangji University Oriental Medical Hospital and treated Bee Venom Therapy over 10 times from November 1998 to October 1999. The results were summarized as follows. 1. The distribution of Sex was 60 females, 40 males, and the average of patients age was $50.6{\pm}1.5years$. 2. The distribution of disease was degenerative arthritis, HIVD of L-spine, RA, etc. 3. The total treated time is 2765 and is observed 361 immume responses. 4. The average of keeping time in immume response is $11.8{\pm}0.6(hr)$, and the cases of over 24hrs is occupied 24.0%. 5. In the correlation between treated times and immume response is generally in inverse proportion. 6. The general aspect of immume response is chilling, heating, powerless, headache, dizziness, etc. 7. $M{\ddot{u}}ller$ Grade II-III was observed only 1%.

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The Effect of Implicit Motor Sequence Learning Through Perceptual-Motor Task in Patients with Subacute Stroke (아급성기 뇌졸중 환자에서 지각-운동 과제를 통한 내잠 학습의 효과)

  • Lee, Mi-Young;Park, Rae-Joon;Nam, Ki-Seok
    • The Journal of Korean Physical Therapy
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    • v.20 no.3
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    • pp.1-7
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    • 2008
  • Purpose: Implicit motor learning is the capacity to acquire skill through physical practice without conscious awareness of what elements of performance improved. This study investigated whether subacute stroke patients can implicitly learn a perceptual-motor task. Methods: We recruited 12 patients with subacute stroke and 12 age-matched controls. All participants performed a perceptual-motor task that involved pressing a button corresponding with colored circles (blue, green, yellow, red) on a computer screen. The task consists of 7 blocks composed of 10 repetitions for a repeating 12-element sequence (total 120 responses). Results: Both groups demonstrated significant improvement in acquisition performance. Reaction times deceased in both groups at similar rate within the sequential block trials (2-5 blocks), and reaction times increased at a similar rate when the task paradigm was transferred from the sequential block trial to the random block trial (5-6-7 blocks). Conclusion: The results of this study suggest that patients with sub-actue stroke can implicitly learn a perceptual motor skill. Although explicit instructions should be used to focus the learner's attention rather than provide information about the task, the application of implicit motor learning strategies in the rehabilitation setting may be beneficial.

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A Study on the Relationship Between the Concern about Well-being Lifestyle and the Perceived Image of Hanji Fiber (웰빙 라이프 스타일 관심과 한지 섬유 이미지 지각의 상관관계 연구)

  • Ju, Jeong-Ah;Shim, Joon-Young
    • Korean Journal of Human Ecology
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    • v.19 no.2
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    • pp.389-398
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    • 2010
  • This study examines the relationship between the concern about well-being lifestyle and the perceived image of Hanji fiber. A survey was conducted among male and female consumers aged 20 and over in Jeonju and Daejon from January 4th to 11th, 2008. A total of 168 responses were analyzed by using descriptive statistics, factor analysis, and ANOVA via the SPSS ver. 12. As a result, four factors were determined in the concern for a well-being lifestyle; product consumption, enjoying culture, using therapy and managing the household. The perceived image of Hanji fiber were classified into four elements; traditional, high-quality, functional and popular images. Among the factors of the concern for a well-being lifestyle and the perceived image of Hanji fibers, a partial relationship was observed. There is a positive relationship, especially between the product consumption factor of a well-being lifestyle and the high-quality and functional image of Hanji fiber. Also, there was a positive relationship between the factor of managing the household and the traditional image of Hanji fiber. However, the therapy interest factor of a well-being lifestyle was negatively related to the traditional image of Hanji fiber.

A Study on Life Style and Behavior Characteristics of the Costume Player (코스튬플레이어들의 라이프스타일과 행동특성에 관한 연구)

  • Jung, Hea-Young;Jung, Hee-Kyeong;Suh, Yong-Han;Oh, Hee-Sun;Lee, Myung-Hee
    • Fashion & Textile Research Journal
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    • v.6 no.1
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    • pp.85-92
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    • 2004
  • Costume plays have been of interest to young people in the recent years. The much increased interest in costume plays has prompted many researchers to verify the behavior characteristics of costume players Despite the importance of the costume play, there has been no systematic study of it. The purpose of this study is to demonstrate the influence of life style on behavior characteristics of the costume player. The subjects of this study were members of the web sits(www.cosmaker.com). A total of 155 subjects responded to the questionnaires and the 143 responses were used for further data analysis. The data was analyzed by factor analysis, cluster analysis, and one-way ANOVA. These were the results of the stud: First, costume player groups are classified into three sub-dimensions: other people-oriented, show-off oriented, and exclusive ego oriented. Second, the behavior characteristics of costume player are significantly shown among those groups.

A Study on Korean Agricultural Extension Officers' Perception of Role Ambiguity According to Restructuring of Agricultural Administrative Systems (농촌지도조직체계의 변화에 따른 농촌지도공무원의 역할모호성에 대한 인식)

  • Ju, Dae-Jin;Kim, Jin-Mo
    • Journal of Agricultural Extension & Community Development
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    • v.19 no.2
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    • pp.211-240
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    • 2012
  • The purpose of this study was to identify korean agricultural extension workers' Perception of role ambiguity according to restructuring of Agricultural Administrative Systems. The target population of this study was selected from 21 centers out of 156 centers. The subjects for study were 728 agricultural extension officers by the cluster sampling drawn from the sampled 21 agricultural extension centers in four clusters. A survey questionnaire was utilized to measure variables of this study. It consisted of role ambiguity scale and demographic items. In this study, role ambiguity scale was translated from the existing scale. Through a pilot test and final survey, reliability and validity of these scales were examined. The data were collected by mail. A total 420 questionnaires out of 728 from 21 agricultural extension centers were returned. After data cleaning, 410 responses were used for analysis. Both descriptive and inferential statistics were applied for data analysis. Major findings of the study were as follows. There were significant differences of the degree of role ambiguity among the local extension workers divided by four clusters. Especially, the degree of role ambiguity of restructured local administrative system were more higher than other clusters, comparatively. Thus, the factors causing the role ambiguity to agricultural extension officers need to be measured it in-depth.

Long-term impacts of Argentine ant invasion of urban parks in Hiroshima, Japan

  • Park, Sang-Hyun;Hosoishi, Shingo;Ogata, Kazuo
    • Journal of Ecology and Environment
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    • v.37 no.3
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    • pp.123-129
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    • 2014
  • Ant communities are well suited for monitoring changes in ecosystems. Although numerous studies have examined the responses of ant communities to environmental disturbance, relatively few long-term studies on ant communities have been undertaken in urban environments. We examined species richness in nine urban parks in Hiroshima, Japan, and compared the survey results with data collected at the same sites by using the same methods in 1999. In both surveys, total of 25 species was recorded: 23 species in 1999 and 20 species in 2012. Non-metric multidimensional scaling analysis revealed that the ant communities consisted of two distinct groups, which could in turn be characterized by three patterns of ant community changes in between the two groups. The first of these community change patterns was characterized by a shift within group 1, but the number of species remained constant (approx. 10 species). The second pattern was characterized by a shift within group 2, but the number of species remained low (approx. 4 species). The third pattern was characterized by a shift from group 1 to group 2 as the abundance of Linepithema humile (Mayr) increased over time. Unlike the first and second patterns, the number of ant species in communities of the third type decreased significantly. These findings suggest that L. humile has a marked effect on the species diversity of indigenous ant communities in urban environments.

The Development and Effects of Timeout Protocol for Safety in Cataract Surgery Patients (백내장 수술 환자 안전을 위한 타임아웃 프로토콜 개발 및 효과)

  • Seo, Eun Hee;Choi, Yeon Hee
    • The Korean Journal of Rehabilitation Nursing
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    • v.18 no.1
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    • pp.29-37
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    • 2015
  • Purpose: This study was conducted to develop effective timeout protocol in coordination with current practice and test its clinical effectiveness in pursuit of safety management for patients undergoing cataract surgery. Methods: A total of subjects were 60 women, 50~65 years old, who visit C ophthalmology clinic in D city. They were assigned to 30 experimental group and 30 control group, respectively. Based on the comprehensive literature review, timeout protocol that was suitable for patients undergoing cataract surgery was developed, and then test its effectiveness by measuring blood pressure, pulse, anxiety and sense of well-being among surgical patients. Results: The timeout protocol was found to reduce blood pressure, pulse, and anxiety and increase well-being among surgical patients. Conclusion: As a results, it is necessary to introduce an effective timeout protocol giving positive responses to surgical patients, hence it should be develop a timeout protocol and explore the effectiveness of the protocol.