• Journal of Embryo Transfer
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• v.13 no.2
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• pp.127-137
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• 1998

This experiment was carried out to investigate the factors affecting superovulation in rabbits and to determine the effect of pFSH and PMSG on ovarian superovulatory responses and embryo production, and the effect of superovulation treatment with a single injection of pFSH dissolved in polyvinylpyrrolidone on the ovarian responses and the embryo quality. The results obtained were suonmerized as follows: Superovulatory response resulted in significantly (P<0.05) higher ovulation rates and more embryos in spring or autumn, compared with summer or winter. Repeated superovulatory treatments with PMSG leaded to a significantly(P<0.05) decreased number of total follicles and recovered ova. Superovulation with pFSH resulted in the higher number of ovulated follicles and recovered ova than with PMSG. A single subcutaneous injection of pFSH dissolved in 25% PVP resulted in the more ovulation points(33.2) and recovered embryos(30.2), which were comparable to the multiple injections of pFSH(44.8 vs 37.7).These results indicated that the treatment with a single injection of FSH dissolved in PVP was an efficient and simple alternative method to the conventional multiple FSH injections for superovulation in rabbits.

• Journal of Nutrition and Health
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• v.28 no.10
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• pp.1004-1014
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• 1995

Effect of age and dietary fatty acid composition on immune responses were investigated in Sprague-Dawley male rets. The animals weighing 88.6$\pm$2.2g were fed 10% dietary fat (W/W, 20% of calorie) with P/S ratio of 0.5, 1 and 2, and in each group, there were three different levels of n-6/n-3 fatty acid ratio; 2, 4 and 8(3$\times$3). The experimental periods were 1 month, 6 months and 12 months. The results of this study were; 1) Weights of thymus and spleen were significantly reduced with increasing age, moreover thymus weights were reduced with increasing the degree of unsaturation in dietarty fatty acid at 12 month. 2) The proportion of splenic lymphocyte in the total T-cell was increased with increased with age. The proportion of helper T-cell was not changed, while the proportion of suppressor T-cell was decreased. Thus at 12 month, the ratio of helpe $r^pressor T-cell was appeared to increase significantly, and showed the tendency to increase by consuming the low amount of dieraty n-3 fatty acid. 3) Proliferation stimulated by Con A or PWM reduced significantly at 12 month in which are high in dietary P/S ratio, representing the similar pattern with decrease in thymus weight. 4) Natural killer cell activities were shown significantly higher at 1 month than those at 6 month or 12 month.th.

• Biomolecules & Therapeutics
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• v.25 no.5
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• pp.482-489
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• 2017

Individual differences in drug responses are associated with genetic and epigenetic variability of pharmacogene expression. We aimed to identify the relevant miRNAs which regulate pharmacogenes associated with drug responses. The miRNA and mRNA expression profiles derived from data for normal and solid tumor tissues in The Cancer Genome Atlas (TCGA) Research Network. Predicted miRNAs targeted to pharmacogenes were identified using publicly available databases. A total of 95 pharmacogenes were selected from cholangiocarcinoma and colon adenocarcinoma, as well as kidney renal clear cell, liver hepatocellular, and lung squamous cell carcinomas. Through the integration analyses of miRNA and mRNA, 35 miRNAs were found to negatively correlate with mRNA expression levels of 16 pharmacogenes in normal bile duct, liver, colon, and lung tissues (p<0.05). Additionally, 36 miRNAs were related to differential expression of 32 pharmacogene mRNAs in those normal and tumorigenic tissues (p<0.05). These results indicate that changes in expression levels of miRNAs targeted to pharmacogenes in normal and tumor tissues may play a role in determining individual variations in drug response.

• International Journal of Contents
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• v.9 no.4
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• pp.78-85
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• 2013

Music functions as a catalyst for various emotional experiences. Among the numerous genres of music, film music has been reported to induce strong emotional responses. However, the effectiveness of film music in evoking different types of emotions and its relationship in terms of which musical elements contribute to listeners' perception of intended emotion have been rarely investigated. The purpose of this study was to examine the congruence between the intended emotion and the perceived emotion of listeners in film music listening and to identify musical characteristics of film music that correspond with specific types of emotion. Additionally, the study aimed to investigate possible relationships between participants' identification responses and personal musical experience. A total of 147 college students listened to twelve 15-second music excerpts and identified the perceived emotion during music listening. The results showed a high degree of congruence between the intended emotion in film music and the participants' perceived emotion. Existence of tonality and modality were found to play an important role in listeners' perception of intended emotion. The findings suggest that identification of perceived emotion in film music excerpts was congruent regardless of individual differences. Specific music components that led to high congruence are further discussed.

• The Journal of Industrial Distribution & Business
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• v.8 no.2
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• pp.11-20
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• 2017

Purpose - The elderly do not want to know what they want and what happiness is, and have no interest in their society. Thus, many studies have been made to investigate real-life situations and to find a solution. Further studies are needed to investigate the effect of the elderly's dating upon happiness. This study investigated the effects of the elderly's dating upon life satisfaction. Research design, data, and methodology - After coding, SPSS Win18.0 was used. The study was investigated as follows. The subjects were 530 elderly of 3 cities in Chungnam who live without children. A total of 512 questionnaire responses were used after we excluded 18 questionnaire because of incomplete responses. Results - The elderly's date value accounted for 3.22 of 5 in full. In this study, the interviewees (82.3%) said normal or higher level to be satisfied with the date. Conclusions - With the extended life span of the elderly, their chances to retain or make new partners have increased. Considering this trend, social workers and others in senior centers should give health services to the elderly to consult and give educational programs to be free from prejudice and conservative attitudes. Most of the elderly had desire to date but thought that with prejudice and bias.

• Journal of Nutrition and Health
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• v.32 no.7
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• pp.781-786
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• 1999

This study was designed to investigate the effects of vitamin E supplementation on radical scavenger activity and immune responses in female judo athletes(n=18). The age and sex matched sedentary students were used as controls(n=15). The initial plasma vitamin E concentration, lipid peroxide level and radical scavenger activity (RSA) were not different between two groups. The supplementation of $\alpha$-tocopheryl acetate(400IU/d) for 4 weeks significantly increased plasma vitamin E concentration of the subjects in both groups. In addition, the decrease in thiobarbituric acid reactive substance(TBARS)(p<0.05) and enhancement of RSA(p<0.05) were observed in both groups. Percentages of total T-cells in the athletic group was lower than that in the control group(p<0.05). However, the ratio of CD4 / CD8(helper T-cal $l^pressor T-cell) was higher in the sports group, due to more decrease in CD8 subset than in CD4 subset. The concentrations of IgG and IgM in the sports group were significantly lower than those in the control group(p<0.05). Therefore, severe training of the athletic group seems to be associated with the changes of supplementation. In conclusion, vitamin E supplementation (400IU/d, 4 weeks) of the female university students improved antioxidative activities of the blood, by decreasing lipid peroxide and enhancing radical scavenger activity. Percentages of T lymphocytes and IgG and IgM concentrations in the athletic group were lower than those in the control group. Meanwhile, vitamin E supplementation had no effects on immune status in both groups.ps.

• Structural Engineering and Mechanics
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• v.1 no.1
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• pp.87-102
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• 1993

A $C^{\circ}$ continuous finite element formulation of a higher order displacement theory is presented for predicting linear and geometrically non-linear in the sense of von Karman transient responses of composite and sandwich plates. The displacement model accounts for non-linear cubic variation of tangential displacement components through the thickness of the laminate and the theory requires no shear correction coefficients. In the time domain, the explicit central difference integrator is used in conjunction with the special mass matrix diagonalization scheme which conserves the total mass of the element and included effects due to rotary inertia terms. The parametric effects of the time step, finite element mesh, lamination scheme and orthotropy on the linear and geometrically non-linear responses are investigated. Numerical results for central transverse deflection, stresses and stress resultants are presented for square/rectangular composite and sandwich plates under various boundary conditions and loadings and these are compared with the results from other sources. Some new results are also tabulated for future reference.

• Journal of the Korean housing association
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• v.26 no.6
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• pp.181-190
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• 2015

This study emphasizes a new senior housing type which can provide individual housing units and common facilities for retirees, particularly who will be retired from universities. It is called a university-based retirement community. This study conducted a questionnaire survey to investigate future residents' needs for architectural environments that included housing types, common facility features, and proximity, and also development methods in response to the university involvement levels. The survey questionnaire was administered in one national university in Korea. A total of 214 responses were valid for statistical analyses. Major findings are as follows: Over 65% of the respondents were willing to live in the university-based retirement community. Regarding the location of the community, they responded the community would not need to be located on campus. Preferred common facilities in the UBRC were indoor fitness centers, the shuttle bus stops connecting to the adjacent areas, and bath and sauna facilities. The respondents emphasized university's contribution toward offering educational programs for UBRC residents. Lastly, their responses to the university role and involvement in the development and construction process were identified. This study results are expected to provide essential information for facilitating the Korean model of university-based retirement communities in the future.

• Culinary science and hospitality research
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• v.23 no.8
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• pp.27-39
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• 2017

This study was to examine how consumption value of female consumers affects impulse consumption and purchase satisfaction when they buy bakery goods, present specific determinant factors that affect them, and identify its influencing factors. The survey was conducted with those who have bought bakery goods of female consumers in Seoul and Kyonggi area, using a convenience sampling method. After a total of 400 responses was collected, 366 responses were included for the multiple regression analyses in order to test the hypotheses. To summarize findings from this study, analysis of the first hypothesis showed that "emotional impulse buying," "stimulating impulse buying," "reminder impulse buying," and "situational impulse buying" among impulse buying factors in consumption value factors had positive effects. The second hypothesis analyzed that "emotional impulse buying," "stimulating impulse buying," and "situational impulse buying" gave positive impacts on "purchase satisfaction," while "reminder impulse buying" had no influence. Analysis of the third hypothesis demonstrated that "consumption value" had positive effects on "purchase satisfaction." These findings were significant to examine consumption value that show the consuming pattern of consumers, analyze influencing factors on impulse buying of female consumers, and further present marketing strategies used for advantageous tools with competing stores to bakery owners or marketers.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2008.11a
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• pp.332-337
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• 2008

The supply of digital homes has been increasing but digital home services which meet consumer needs under the various conditions have not identified. The purpose of the study was to investigate the residents' characteristics living in digital apartments with comparison of their innovativeness toward technology. Residents who lived in two apartment complexes equipped with fundamental digital home services(Level 1 service) were selected to conduct the survey. A total of 500 responses were used for data analyses. Responses were classified into three groups based on their innovativeness toward technology for data analyses. The results of the study showed that residents' socio-demographic and housing related characteristics differed according to their acceptance trait of new technology. Early adopters and early majority were younger, higher income, and more educated than late adopters. Also, they were more likely to be renters and consider installation of digital home services before they moved in. Respondents who had higher innovativeness tended to experience more positive life changes after using digital home services and possessed more and many digital appliances. Remote control and remote meter reading service were the most preferable features among digital home services without no differences in three groups.