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Effect of Arsenic on Immunity, Oxidative Enzyme and Various Hematological Parameters in Cross Bred Calves

  • Mishra, C.S.;Mani, Veena;Kaur, Harjit
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.4
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    • pp.497-501
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    • 2005
  • An experiment was conducted on crossbred male calves to study the effect of arsenic (As) on immunity status and certain hematological parameters. Ten crossbred male calves of 3-4 months of age were distributed into two equal groups. Group I was kept as control, whereas, group II was supplemented daily with 50 ppm As (as $As_sO_3$) up to 90 days, in the diet. Calves of both groups were fed as per ICAR standards and their requirements were fulfilled by feeding concentrate mixture and green oats. All calves were kept under similar managemental conditions. Blood samples were collected at fortnightly intervals to estimate various haematological parameters and superoxide dismutase (SOD) enzyme activity. Serum Ig and serum glutamic pyruvate transaminase (SGPT) were also measured. Cell-mediated immune responses of the calves were monitored at 0, 45 and 90 of experimental feeding, through lymphocyte proliferation. No change in blood total leukocyte counts (TLC), differential leukocyte counts (DLC), packed cell volume (PCV), haemoglobin (Hb) and SGPT was observed with As supplementation. A decrease in SOD activity was noticed in group II calves. Stimulation index (SI) for lymphocyte proliferation decreased from 1.14 to 0.79 in group II calves during 90 days experimental feeding, whereas, there was no change in SI values in group I indicating significant decrease in immune response of As supplemented calves. Blood As concentration increased in group II calves with the decrease in immune response. Short term supplementation of As to growing calves suggested suppressive effects on cell-mediated immunity. However, long term experiments are required to demonstrate clearly the efects of this toxic metal in calves.

Exploring Factors Influencing Users' Continuance Intention in Social Networking Sites (사회네트워킹 사이트 이용자 지속의도에 영향을 미치는 요인에 관한 탐구)

  • Park, Ji-Hong
    • Journal of the Korean Society for information Management
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    • v.25 no.4
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    • pp.205-226
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    • 2008
  • The success of social networking sites (SNSs) may depend on many factors. Continuance use of SNSs is one of these. Especially, in the Web environment where users can leave one service with a single mouse click, maintaining existing members cost much time and efforts. Without continuance use of SNSs, SNS-based service would not create any value. This study focused on identifying factors influencing users' continuance intention in SNSs. Based on relevant literature review, six influencing factors were initially identified. They were reputation, relational capital, knowledge quality, compatibility, personalization, and satisfaction. Web-based questionnaire survey was conducted and a total of 325 usable responses were collected. Reliability test and two rounds of exploratory factor analyses resulted in identifying five factors. The relationship between the factors and the continuance intention was tested by using multiple regression analyses. The analyses revealed that satisfaction was the most significant factor. Knowledge quality and relational capital also had significant effects while reputation and personalization did not have significant effect on continuance intention. Instead, reputation and personalization showed significance in influencing satisfaction.

Relationship among Marketing Activities, Brand Equity, and Consumer Behavior by Life Cycle of Fashion Brand (패션상표의 수명주기에 따른 마케팅 활동, 상표자산, 소비행동 간의 관계)

  • Jung, Na-Young;Kim, Mi-Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.34 no.9
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    • pp.1454-1469
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    • 2010
  • Brands have their own life cycles and exert a great influence on the marketing activities of companies. This study examines the marketing activities according to a brand life cycle and measures the scope of their performances. The research divides a fashion brand life cycle into three stages through the analysis of secondary data, and validates the causal relationship between marketing activities, brand equity, and consumer behavior according to the brand life cycle. A total of 573 responses were analyzed through a factor analysis, path analysis, and paired t-test with SPSS 12.0. The results are as follows: According to the analysis of the relationship between marketing mix and brand equity, distribution strategies are effective at the introduction/growth stage and the continuation stage. Advertisement strategies should be a main focus at the maturity stage for brand awareness. Throughout all the stages, product strategies wield the greatest influence on the brand image. Among brand equity components, the brand image has an influence on consumer behavior at every stage of the cycle while the brand awareness has no significant effect on consumer behavior. The marketing mix component that has the greatest impact on consumer behavior is product. Contrary to general expectations, price has a negative or insignificant effect on consumer behavior at every stage of the cycle. The results illustrated in this study help to understand the life cycle of fashion brands and characteristics different from consumer goods. Thus, fashion companies should identify at which stage their brands are positioned and develop different strategies to fit each stage.

Effects of Product and Situation on Internet Browsing Behavior for Fashion Products (의류 제품특성, 상황특성이 소비자의 인티넷 탐색 행동에 미치는 영향)

  • Shim, Soo-In;Jang, Se-Jung;Lee, Yu-Ri
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.7
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    • pp.1046-1055
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    • 2008
  • The purpose of this study is to investigate the effects of product variables(i.e., fashionability, brand fame) and situational variables(i.e., time constraint, usage occasion) on the internet browsing behavior (i.e., prepurchase search; ongoing search for products, stores, fashion trends, promotions, and post-purchasing information) for fashion products. This study developed hypothetical scenarios based on the factorial design of the two independent variables for the survey with a questionnaire. All items in the questionnaire were measured on a six-point scale. By convenience sampling and on-line survey, a total of 209 usable responses were used for further analyses. The results show as follows; firstly, respondents more intensively browse for information search on products, stores and fashion trends when the style of browsing products is trendy. Secondly, whether the fashion products have a famous brand name or not has a significant influence on browsing behavior for stores and fashion trends information search. Thirdly, time constraint is found to influence significantly on respondents' browsing for promotions information search. Lastly, occasion for product worn shows a significant influence on browsing behavior for stores and fashion trends information search. The managerial implications are provided based on findings.

Physiological Responses of Wearing Industrial Gaiters in a Hot Environment (더운 환경에서 산업용 각반 착용 시 인체생리반응)

  • Choi, Jeong-Wha;Park, Joon-Hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.7
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    • pp.1129-1136
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    • 2008
  • The gaiter is one of the personal protective equipments worn in various industrial sites. This study was performed on humans to investigate the physiological strain of wearing gaiters and to compare control gaiters that are currently on the market and new gaiters that are developed for alleviating heat stress. Experiments were conducted in a climatic chamber of WBGT $30.0\pm0.7^{\circ}C$ under five differed experimental conditions: None, Control A, Control B, New A, New B. The results were as follows. The temperature inside gaiters was significantly lower in both New A and New B than in both Control A and Control B and the difference between news and controls was 1$^{\circ}C$ (p<.01). The humidity inside gaiters in both New A and New B were higher than that in Control A, and lower than that in Control B (p<.01). The outermost surface temperature of the gaiter was the lowest in None and it increased in the following order: New B < New A < Control A < Control B. Mean skin temperature was higher by 0.14$^{\circ}C$ in wearing gaiters than in no gaiters. Skin temperatures in lower body were lower in Control than in New and skin temperature in upper body were higher in Control than in New (p<.01). Local sweat rate, total weight loss and subjective sensations did not show a significant difference according to the gaiters. It was concluded that wearing gaiters affected distribution of skin temperature and local sweat rate.

Effects of Housing Systems on Physiological and Immunological Parameters in Laying Hens

  • Kang, Sung-Young;Ko, Young-Hyun;Moon, Yang-Soo;Sohn, Sea-Hwan;Jang, In-Surk
    • Journal of Animal Science and Technology
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    • v.55 no.2
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    • pp.131-139
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    • 2013
  • The aim of this study was to assess the effects of housing systems on physiological and immunological responses as stress indicators in laying hens. A total of 500 White Leghorn aged 16 weeks were allotted into ten conventional cages (10 birds/cage and 810 $cm^2$/bird) and four floor pens (100 birds/pen and 2,800 $cm^2$/bird) for 24 weeks. The hens housed in conventional cages with higher stocking density resulted in a significantly (P<0.05) lower BW compared with those housed in floor pens with lower stocking density without affecting the relative weights of immune organs between housing conditions. In plasma biochemical values, cholesterol and corticosterone were significantly (P<0.05) lower in the hens housed in floor pens compared with those housed in conventional cages. In pro-inflammatory cytokines, hepatic interleukin (IL)-10 and interferon-gamma (IFN-${\gamma}$) levels were significantly (P<0.05) higher in the hens housed in conventional cages compared with those kept in floor pens. Splenic and thymic IFN-${\gamma}$ expression was significantly (P<0.05) up-regulated in the hens kept in conventional cages compared with those kept in floor pens without affecting IL-1, IL-10, lipopolysaccharide- induced tumor necrosis factor-${\alpha}$ factor (LITAF) and inducible nitric oxide synthase (iNOS). In the bursa of Fabricius, IL-10 and iNOS expression of the hens housed in conventional cages were significantly (P<0.05) higher compared with those of the hens housed in floor pens. In conclusion, layers housed in conventional cages enhanced plasma cholesterol, corticosterone and some pro-inflammatory cytokines in the immune organs compared with those in floor pens.

Ground-based Observations of the Polar Region Space Environment at the Jang Bogo Station, Antarctica

  • Kwon, Hyuck-Jin;Lee, Changsup;Jee, Geonhwa;Ham, Young-Bae;Kim, Jeong-Han;Kim, Yong Ha;Kim, Khan-Hyuk;Wu, Qian;Bullett, Terence;Oh, Suyeon;Kwak, Young-Sil
    • Journal of Astronomy and Space Sciences
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    • v.35 no.3
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    • pp.185-193
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    • 2018
  • Jang Bogo Station (JBS), the second Korean Antarctic research station, was established in Terra Nova Bay, Antarctica ($74.62^{\circ}S$ $164.22^{\circ}E$) in February 2014 in order to expand the Korea Polar Research Institute (KOPRI) research capabilities. One of the main research areas at JBS is space environmental research. The goal of the research is to better understand the general characteristics of the polar region ionosphere and thermosphere and their responses to solar wind and the magnetosphere. Ground-based observations at JBS for upper atmospheric wind and temperature measurements using the Fabry-Perot Interferometer (FPI) began in March 2014. Ionospheric radar (VIPIR) measurements have been collected since 2015 to monitor the state of the polar ionosphere for electron density height profiles, horizontal density gradients, and ion drifts. To investigate the magnetosphere and geomagnetic field variations, a search-coil magnetometer and vector magnetometer were installed in 2017 and 2018, respectively. Since JBS is positioned in an ideal location for auroral observations, we installed an auroral all-sky imager with a color sensor in January 2018 to study substorms as well as auroras. In addition to these observations, we are also operating a proton auroral imager, airglow imager, global positioning system total electron content (GPS TEC)/scintillation monitor, and neutron monitor in collaboration with other institutes. In this article, we briefly introduce the observational activities performed at JBS and the preliminary results of these observations.

Remediation of Contaminated Sites in Canada

  • Koo, Jahak
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 1996.11a
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    • pp.39-49
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    • 1996
  • Hundreds of contaminated sites have been generated due to the past mismagement of toxic substances, the lack of adequate environmental controls and ignorance of the potential environmental impacts of general activities in Canada. The general public, industry and governments have been addressing the contaminated sites with a number of cleanup responses. Environmental protection and remediation have become top priorities for the public and private sectors alike in Canada. Between the late 1980s and the early 1990s, the Canadian Environmental Protection Act and Canada's Green Plan were followed by provincial and territorial laws and policies to regulate contaminated sites. The National Contaminated Site Remediation Program(NCSRP) was initiated in 1989. It has been administered through bilateral agreements between the federal and participating provincial/territorial governments. They have committed a total of $250 million toward orphan site cleanup and technology development/demonstration over a five year period. The federal government has committed an additional $25 million to assess contaminated sites on federal crown land. Over 40 orphan high-risk contaminated sites, over 230 federal sites and over 35 technology development/demonstration projects have been addressed. The Canadian Council of Ministers of the Environment has developed a series of guidance documents to ensure a consistent and successful implementation of the Program. The management/regulation scheme of contaminated sites generally consists of: 1) identifying and investigating sites, 2) determining site contamination, 3) recognizing responsibility and liability, 4) assessing priority for remediation, 5) activation, evaluation and implementing remediation options, and 6) documenting remediation completion. The NCSRP supported the successful development/demonstration of a wide range of innovative remedial technologies. They are related to stabilization/solidification, thermal washing/flushing, advanced oxidation, sonics, and groundwater contaminated with hydrocarbons, PAHS, PCBs, heavy metals, and other hazardous pollutants in a variety of site environments.

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Comparison of Efficacy of Newcastle Disease Virus $B_1$ Vaccine by Different Administration Method in Commerical Layer Chickens (뉴캣슬병 $B_1$ 생독백신의 효능비교)

  • 정만호;강춘원;노용기;박진열
    • Korean Journal of Veterinary Service
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    • v.13 no.1
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    • pp.96-102
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    • 1990
  • The immune responses of commercial layer chickens against Newcastle disease(ND) were compared among different administration methods and times of vaccination during 4 weeks of age. A total of 372 day-old chickens were divided into 4 groups of 93 birds each. Each of 3 groups was received a commercially available B$_1$live vaccine via drinking water, eye instillation or spray method at one, 14 and 28 days of age. One group was used as an unvaccinated control. At two and 4 weeks after each time of vaccination, 15 birds from each group were collected randomly out and challenged with virulent ND virus at the dose of $10^5E1D_{50}$ per bird. Ten to 15 birds from each group were bled at two weeks intervals from day old to 8 weeks of age for hemagglutination inhibition antibody titer, The protection rate was generally low regardless of the times of vaccination although two or more times vaccination gave higher protection than once vaccination. The low protection was considered due to low titer of the vaccine used since the vaccine titer was less than $10^{3.5}EID_{50}$ per bird. Spray method gave better protection compared to eye instillation or drinking water method which resulted in lowest response. Majority of birds showed clinical signs of ND between 3 and 6 days after challenge. Death occured one or two days after onset of symptoms. Major clinical signs observed were depression(94%), anorexia(84%), diarrhoea(29%), difficult breath(15%) and torticollis(10%). Hemorrhagic lesions on post mortem were seen in duodenum(51%), trachea(35%), illeum(13%), ceacal tonsil(11%), proventriculus(10%) and some other odrgans.

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Search for Novel Stress-responsive Protein Components Using a Yeast Mutant Lacking Two Cytosolic Hsp70 Genes, SSA1 and SSA2

  • Matsumoto, Rena;Rakwal, Randeep;Agrawal, Ganesh Kumar;Jung, Young-Ho;Jwa, Nam-Soo;Yonekura, Masami;Iwahashi, Hitoshi;Akama, Kuniko
    • Molecules and Cells
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    • v.21 no.3
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    • pp.381-388
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    • 2006
  • Heat shock proteins (Hsp) 70 are a ubiquitous family of molecular chaperones involved in many cellular processes. A yeast strain, ssa1/2, with two functionally redundant cytosolic Hsp70s (SSA1 and SSA2) deleted shows thermotolerance comparable to mildly heatshocked wild type yeast, as well as increased protein synthesis and ubiquitin-proteasome protein degradation. Since mRNA abundance does not always correlate well with protein expression levels it is essential to study proteins directly. We used a gel-based approach to identify stress-responsive proteins in the ssa1/2 mutant and identified 43 differentially expressed spots. These were trypsin-digested and analyzed by nano electrospray ionization liquid chromatography tandem mass spectrometry (nESI-LC-MS/MS). A total of 22 non-redundant proteins were identified, 11 of which were confirmed by N-terminal sequencing. Nine proteins, most of which were up-regulated (2-fold or more) in the ssa1/2 mutant, proved to be stress-inducible proteins such as molecular chaperones and anti-oxidant proteins, or proteins related to carbohydrate metabolism. Interestingly, a translational factor Hyp2p up-regulated in the mutant was also found to be highly phosphorylated. These results indicate that the cytosolic Hsp70s, Ssa1p and Ssa2p, regulate an abundance of proteins mainly involved in stress responses and protein synthesis.