• Herbal Formula Science
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• v.30 no.2
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• pp.101-108
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• 2022

Objectives : The prevalence of chronic cough in Korea is 2.5 ± 0.2% among people over the age of 40, and the rate of idiopathic chronic cough is high. Hemoptysis is one of the respiratory emergency symptoms, and the cause is unknown in 30% of cases. This case report is to confirm the treatment of korean medicine for Idiopathic chronic cough and hemoptysis. Methods : A 74 year old female patient with idiopathic chronic cough and hemoptysis was treated with korean medicine. The patient was treated from july 21, 2021 to september 24, 2021, using herbal medicine (Chungpyebyeolgab-sangagam) and acupuncture(Sa-Am Acupunture Lung Tonifying, CV22). Idiopathic chronic cough and hemoptysis were assessed by VAS. Results : Idiopathic Chronic cough and hemoptysis improved through Korean medicine treatment. Although taking codeine phosphate and transamin was stopped, the improvement of symptoms was maintained. Conclusions : This study suggests that korean medicine treatment may be an effective therapy for treatment of idiopathic chronic cough and hemoptysis.

• The Journal of Korean Medical History
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• v.35 no.1
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• pp.69-86
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• 2022

This study examined guange (關格) in Yixuerumen (醫學入門) from a new perspective and evaluated its value in terms of emergency medicine. We compared and analyzed the definition, symptoms, and treatment methods of guange in Yixuerumen with related clinical presentations in modern medicine. Guange includes nausea and vomiting, dysphagia, dysuria, and constipation without diarrhea. A representative disease related to dysuria is uremia, while one related to constipation, nausea, and vomiting is enterocleisis, and and a third related to dysphagia is chronic esophagitis and esophagus cancer. Li Chan, the author of Yixuerumen, recognized guange as an emergency of serious eating and elimination disorder as various symptoms of diseases (病症) gradually get worse from the perspective of external diseases (外感病) and miscellaneous diseases (雜病) and handled it in various ways including yin-tonifying medicinals (補陰藥), qi-tonifying medicinals (補氣藥), qi-regulating formulas (理氣劑), phlegm-dispelling formulas (去痰劑), and "water rising, fire falling" formulas (水升火降) in addition to emetic formulas (催吐劑), diuretic formulas (滲利劑), and interior-attacking formula (攻裏劑). Concepts like guange in Yixuerumen were somewhat useful when handling the applicable emergencies at the level of then medical treatment.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.1
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• pp.69-74
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• 2005

In Oriental medicine the primordial Qi and the defensive Qi are considered as important for immunity. Therefore it is anticipated that the improvement of the primordial Qi and the defensive Qi can enhance the ability of immune cells. This experiment was conducted to investigate how Ginseng Radix, Astragali Radix, Atractylodis Rhizoma Alba, Glycyrrhizae Radix, representative of Qi tonifying herbs, affect the immune system in terms of controlling and balancing immune cells. Using the MTS assay, increased proliferations were observed from herbal treated cells, among which Gins-eng showed the highest proliferation. When splenocytes were activated with anti-CD3 plus herbal extracts, levels of IFN-g and IL-4 were increased but those of IL-2 showed little change compared with the control cells. Levels of IL-2, IFN-g and IL-4 were increased in purified CD4 T cells when activated with anti-CD3/anti-CD28 but at $100\;{\mu}g/ml$ of Astragali and Atractylodis, levels of IL-2 were decreased by 11% and 42%, respectively and those of IFN-g were decreased by 55% and 12%, respectively. Under Th1/Th2 polarizing conditions, levels of IFN-g in Th1 cells treated with herbal extracts were all decreased but when it comes to IL-4, its levels were increased in Ginseng and Glycyrrhizae treated cells but decreased in Astragali and Atractylodis treated cells. Taken together, the data show that compared with other qi tonifying herbs, Ginseng and Glycyrrhizae have a tendency to favor Th2 cell differentiation in vitro.

• Korean Journal of Acupuncture
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• v.30 no.2
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• pp.88-96
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• 2013

Objectives : In the acupuncture treatment of Korean Medicine, the Tonifying or Purging depending on how many times the needle is rotated has been used widely. However, there is little evidence about the optimal number of rotation. This study, therefore, was aimed to investigate the optimal number of rotation. Methods : Heart rate variation was measured before and after exercise in 20 healthy adults. Acupuncture was performed at PC6 immediately after exercise according to the protocol of each group without remaining. Pre-exercise and post-exercise measurements were compared and the rotation number that produced statistically significant difference was investigated. Results : Significant differences were found in the heart rate variation and R-R interval Average, between non-rotation group (control) and both of 15 times rotation group of tonifying and 6 times rotation group of purging. Conclusions : Significantly effective number of rotation in the effect of PC6 on the HR and RRAv was 15 times in the tonifying and 6 in the purging respectively.

• The Korea Journal of Herbology
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• v.23 no.1
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• pp.127-130
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• 2008

The hysterocele means the descent state of uterus than a normal position. We had medical treatments 3 patients with hysterocele (grade 1, 2 or 3) by invigorating qi and tonifying the kidney. And we had significant effects on patients with hysterocele grade 1, 2 by Soeuminbojungikgitang and Gamibojungikgitang. But we didn't cure a patient with hysterocele grade 3.

• The Journal of Korean Medical History
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• v.23 no.2
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• pp.89-101
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• 2010

Lee Jae Won is a scholar who wrote the most in Euirim, a representative Oriental Medical magazine after the liberation of Korea, on the Sa-am Acupuncture Method. In order to understand the principles of this method, he proposed rather distinctive theories called the Comparative Pulse Diagnosis and the Five Constitutions. Lee Jae Won distinguished the deficiency and exuberance of the Five Phases through the Comparative Pulse Diagnosis, and set harmonizing the Five Phases by tonifying the deficient and purging the exuberant as the object of the Sa-am Acupuncture Method. He took pulses from both the patient's hands and distinguished the deficiency and exuberance of the five viscera. Then, he balanced the Five Phases by tonifying the weakest viscus and purging the strongest viscus. Lee Jae Won argued that because the Five Constitutions are something that one has innately, people suffer from differnet diseases according to their constitutions. Therefore, he argued, when treating a patient, one should first decide the constitution of the patient and then treat the patient according to his/her deficiency or exuberance. From the late 50's to early 60's, Lee Jae Won wrote Acupuncture and Moxibustion According to Yin-Yang and the Five Phases, explaining the principles of the Sa-am Acupuncture Method and its applications. Seen from this, Lee Jae Won is a person from whom we can confirm the historical lineage of the Sa-am Acupuncture Method after the liberation of Korea.

• The Journal of Korean Medicine
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• v.21 no.3
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• pp.3-8
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• 2000

1. Definition : Bee-venom therapy does not involve actual bee-stings: it is a treatment method with acquired bee-venom extract through the electric stimulus on the bee, It is injected subcutaneusly on the acupuncture point after refining, according to the diagnosis of constitution and disease. 2. History : Around 2000 B.C., records that Bee-venom was used for therapy were written in the medical book of Babylonia and Papirus of ancient Egypt. Hippocrates, who is called the father of Medicine, said that Bee-venom is Arcanum, which means mysteric medicine. In Oriental medicine, B.C. 200, there was a clinical record that the meat suspended in front of the bee house on the tree in order to get bee-venom, was attached on the lesion. 3. Mechanism of Action : There are two aspects: 1) The effect of stimulating acupunture point It is similar to the chemical moxa. I think that there are several methods of stimulating the acupuncture point： For example, a simple needle is a mechanical stimulus, Moxa is a heating stimulus and electric and Raser acupunture etc. And another stimulus: in the ancient orient, a chemical stimulus called Chungu(Tianjiu), is attached to the lesions by using grinded insects (ex. Mylaris phalerate PALL.) which have toxin. So Bee venom therapy is similar to this. 2) The effect of biochemical ingredients Bee venom consists of 40 kinds of ingredients. For example, me Iii tin, Apamin, Pospholipase A2, MCD peptide, Adolapin and so on. They have effects which have been proven through experimentation l) tonifying mechanism of the body through increasing hormon secretion 2) tonifying immune system through proliferation of WBC, lymphocytes, macrophage 3) anti-inflammatory reaction Therefore Bee venom therapy is the representative 3rd Medicine, which combined East & West medicine. 4. Application of disease : L.B.P and HIVD, O.A, R.A, degenerative arthritis, shoulder pain and other pain diseases. 5. Therapic methods : According to constitution and disease, proper concentration of bee venom is injected on acupunture point, 2 times a week. Generally one term is consisted of 15times. 6. Contraindication : Heart disease, TBc, DM, kidney disease(nephritis), pregnancy, woman in menstruation 3-4 persons per 100,000 persons may have severe allergic reaction.

• Journal of Society of Preventive Korean Medicine
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• v.4 no.2
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• pp.25-56
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• 2000

Trace element are involved in enzymatic activities, immunological reactions. physiological mechanisms. Deficiency in some trace elements, such as iron and iodine. is still an important health problem, The role of trace elements deficiency is suspected in various clinical situations and is now confirmed by well designed supplementation studies. However, the importance of trace elements as chinese herbal constituents is not sufficiently appreciated by the oriental medical profession, although in recent years a significant increase of new finding on their essential character in chinese herbal medicine occurred. It is well known that herbal medicine contains a variety of trace elements which would show therapeutic effects with active components in herbal medicine . In china, recent work showed some positive correlation between trace element and traditional chinese medicine (TCM) in terms of therapeutic effects even if their role in therapeutic effects is still obscure. In korea, not much attention has been on the therapeutic importance of trace element contained in herbal medicine Here, the therapeutic effects of trace element in TCM were reviewed and summarized. 1. Iron, copper, zinc and manganese are mainly contained in TCM. In addtion, chromium, magnesium, molybdenum, nickel, alminium, cobalt, arsenic and selenium has been studied for their therapeutic effects 2. Zinc, is decreased in patients who have deficiency of kindney(腎虛) and chronic disease. Fe is decreased in patients who have deficiency of blood(血虛). However copper is increased in patients who have chronic disease and hepatic disease.3 Iron concentration is high in herbs used for tonifying and nourishing yin or blood(補陰補血藥) Zinc concentration is high also in herb used for tonifying kidiney and vital essence(補腎補精藥). In addition. copper concentration Is high in herb used for replenishing qi(補氣藥) 4 In herbal drugs, the therapeutic substances in TCM are not only organic but also inorganic. It seems that trace elements would be one of components in herb for its therapeutic effects. This indicates that therapeutic effects of TCM should be extended not only to herb itself, bur also to trace elements contained in herb.

• Journal of Sasang Constitutional Medicine
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• v.9 no.1
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• pp.213-243
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• 1997

After studying about the formative process and theory concerning So-Yang In(少陽人)'s prescriptions, Some principles were founded. Those were summarized as follows. 1. Lee Jae Ma(李濟馬) established the theory and remedy about the So Yang In's diseases, and the formation of So Yang In's prescriptions was based on those theories and remedies 2. As the emprical prescription of So Yang In's diseases, ten pre-scriptions of Discussion of Cold-Induced Disorder(傷寒論) and nine of Won Myung dynasty period(元明時代) were described in Dong Eui Su-Se Bo Won(東醫壽世保元), and I could confirm that the formation of So Yang In's presciptions was based on those emprical prescriptions. 3. The pathological characteristics of emprical prescriptions of So-Yang In's diseases in Discussion of Cold-Induced Disorder(傷寒論) were completely corresponded with the principle of So Yang In's diseases, and we could know that emprical presciptions of diseases that were the base of So Yang In's prescriptions were selected by the principle of So Yang In's diseases. 4. In the serious cases of So Yang In's diseases, So Yang In's pre-scriptions were mostly made up of tonifying and nourishing yin medicine(補陰藥物) that dirrectly rufill the damaged Eum Chung Zi Ki(陰淸之氣). According to the above results, it could be concluded that Lee Jae-Ma(李濟馬) made So Yang In's prescriptions with emprical pre scri-ptions that were based on the theory of So Yang In's diseases and concluded that So Yang In's prescriptions were made up of tonifying and nourishing yin medicine(補陰藥物) in the serious cases of diseases.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.7 no.1
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• pp.15-34
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• 1994

This is a literature Study on ophthalmologic disease remedies of the four famous physicians in Jin Yuan period. The results were as follows: 1. Yu Wan So regarded the cause of ophthalmologic disease as the wind and heat(風熱), the blood deficiency(血少), or the deficiency of vital function and essence ,of the kidney(腎氣虛). For each treatment he used the method to remove wind and heat(除風散熱), the tranquillizing and tonifying method to nourish the heart and to relieve mental strain due to dificiency of vital essence(養血安神). the method to nourish Yin in the kidney(補腎水). The important nature of the these medicines is bitter and cold. 2. Jang Jong Jeung regarded the cause of ophthalmologic disease as the blood excess(血太過). or the blood deficiency(血不及). or the fire and heat(火熱). For each treatment he used the method to extract blood(出血療法). the method to nourish the liver and the kidney(補肝腎療法). or the method of vomiting and diarrhea(吐不法). The medicines are usuallly classified into external treatment medicines(外用藥). medicines to disintegrate mass(破積聚藥). purgating medicines(攻下藥). 3. Lee Dong Won regarded the cause of ophthalmologic disease as the spleen and the stomach weakness(脾胃虛弱), excessive fire in the heart(心火太盛). For each treatment he used the method to tranquillize the spleen and the stomach (調理脾胃). the tranquillizing and tonifying method to nourish the heart and to relieve mental strain due to deficiency of vital essence(養血安神). 4. Ju Dan Gye regarded the cause of ophthalmologic disease as the wind and heat(風熱). the blood deficiency(血少). the mental exhaustion(神勞). the kidney weakness(腎弱). For each treatment he used the method to remove wind and heat(除風散熱), the method to nourish blood and yin water(養血補水), the method to relieve mental strain and to remove spiritual heat(安腎瀉神火). the method to nourish yin water(養陰水). These drugs are usually classified into the medicines to remove endogenous heat(淸熱藥). the medicines to nourish yin(補陰藥).