• Korean Journal of Pharmacognosy
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• v.31 no.3
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• pp.325-334
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• 2000

Rhizoma Rehmanniae Preparata is a Chinese herbal tonic. The hemopoietic effects of Rhizoma Rehmanniae Preparata(4-time steamed Jihwang, 4-time steamed double dose Jihwang, 8-time steamed Jihwang, 8-time steamed double dose Jihwang) were examined using in vitro rat(SD) model. Cyclophosphamide(150 mg/kg) was injected into experimental groups and control group to induce bone marrow suppression. Oral administration of Rhizoma Rehmanniae Preparata suppressed hormone levels of $T_4\;and\;T_3$. Reticulocyte count was increased by the bone marrow suppression.

• Korean Journal of Pharmacognosy
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• v.2 no.2
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• pp.89-93
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• 1971

This study is about the five species of the genus Thalictrum growing abundantly in South Korea. Dried roots of plants; T. aquilegifolium var. japonica, T. simplex var. affine, T. actaefolium, T. tuberiferum were compared by morphological observation and screening test on the ingredient extracted by methanol, ether etc.. The experiments by thin-layer chromatography was at tempted to find out the similarity and the difference among them. In conclusion, the author found that: 1) A special component similar to coumarin was found under UV-ray from T. actaefolium. 2) By thin-layer chromatography, they show the corresponding spot supposed to be that of berberine and magnoflorine according to the $T_{ABLE}\;IV$. Therefore it is worthwhile considering that Thalictrum species would be a substitution for Epimedium species used as a tonic. 3) Thalictrum species has resemblance of ingredient and chemotaxonomy gives more help to classify them than the morphology.

• Korean Journal of Pharmacognosy
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• v.43 no.2
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• pp.98-100
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• 2012

Korean folk medicine 'DeungNaMu' has been used mainly to cure apoplexy, pain of the stapes and tonic for weak man. With regard to the botanical origin of DeungNaMu, it has been considered to be Wisteria species of Leguminosae, but there was no pharmacognostical confirmation on it. To clarify the botanical origin of 'DeungNaMu', the anatomical characteristics of the branches of Wisteria species growing wild in Korea, Wisteria japonica and W. japonica forma. alba were studied. As a result, it was clarified that DeungNaMu was the branches of Wisteria japonica.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.3
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• pp.612-617
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• 2005

Astragali Radix(AR), is a popular tonic herb prescribed for 'insufficient qi' in Korea, Japan and China. The present study examined the effect of AR ethanol extract on ovalubumin induced allergic mouse model. AR administration reduced levels of IFN-gamma, Interleukin(IL)-4, IL-5 and total IgE in the OVA induced allergic inflammation. It also protected the upper airway respiratory epithelium from being damaged by the OVA induced inflammation. Taken together, our results showed that the use of AR alone proved to down-regulate Th1 and Th2 cytokine production and play a protective role in tissue damage in allergic disease.

• Science of Emotion and Sensibility
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• v.2 no.1
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• pp.137-145
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• 1999

열 두 명의 피험자가 안정상태 일 때, 백색 소음에 노출되었을 때, 백색 소음 하에서 기억과제에 주의를 기울일 때, 백색 소음 하에서 기억 검사를 받을 때, 기록된 뇌파에 대해 relative power spectrum 분석을 하였다. 뇌파는 전두, 측두, 후두 영역에서 단극 유도법으로 기록되었다. 분석 결과, 백색 소음에만 노출되었을 때나, 백색 소음 하에서 기억과제에 주의를 기울일 때나 비슷한 전기피질(electrocortical) 반응이 나타났다. 즉, delta power의 증가, 알파 blocking, fast beta power의 증가, 스트레스를 일으킨다고 피험자들이 평정한 배색 소음 하에서 기억검사를 받을 때에도 동일한 뇌파 패턴이 나타났지만 그 크기가 유의하게 컸다. 정보를 지각할 때 전형적으로 나타나는 반응을 유발하는 스트레스원에 수동적으로 노출되었을 때("intaki"상황)의 생리 반응과 스트레스 상황에 적극적으로 대처할 때("rejection")의 생리 반응을 구분하는 이론 틀 아래서 데이터를 해석하였다. 스트레스 후 기간에 대부분의 뇌파 변수들이 기저선 수준으로 회복된 것으로 보아 사용한 스트레스 유발 모델은 단기적 스트레스 반응만을 유발한 것으로 보인다. 이는, 더 장기적으로 지속되는 스트레스원을 사용하게 되면, tonic상태의 전기피질 반응이 나타날 것을 시사한다.기피질 반응이 나타날 것을 시사한다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.22 no.2
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• pp.153-160
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• 1996

A novel simple method to detect vitamins in cosmetic products by gas chromatography-mass spectrometry(GC-MS) has been developed. Three vitamins(panthenol, cholecalciferol and tocopherol) were used for this study. Vitamins were prepared by dissolving in tetrahydrofuran(THF), and silylated with bis-trimethylsilyltrifluoroacetamide-trichloromethylsilane(BSTFA). Silated vitamins were separated on a fuses-silica capillary column coated with DB-5. The identification of each vitamin was accomplished by retention time and mass spectrum library search with a computer, and the quantitation was made in the selected-ion monitoring(SIM) mode of GC-MS. SIM mode had given sensitivity to determine 50pg of panthenol, 285pg of cholecalciferol and 130pg of tocopherol. Linearity was maintained over the range 0.005-0.20% for each vitamin. Each cosmetic product(i.e. hair tonic and lotion) was found to contain amounts of the vitamins. This method was sensitive and gave 77.5-99.9% recovery of each vitamin from these cosmetic products. From these results, we concluded that silylation with BSTFA followed by GC-MS analysis allows the simple, covenient and exact determination of panthenol, cholecalciferol and tocopherol.

• Journal of Korean Neurosurgical Society
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• v.49 no.3
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• pp.190-193
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• 2011

Disseminated cysticercosis is a rare form of cysticercosis in which the cysticerci spread out through the whole body. We report the first case of a 39-year-old Mongolian with disseminated cysticercosis. He visited our hospital with generalized tonic-clonic seizure. After extensive investigation from brain computed tomography (CT), spine magnetic resonance imaging (MRI), whole body MRI and pathologic biopsy, he was diagnosed as having cysticercosis involving the brain, subcutaneous tissue, and skeletal muscles through the whole body. We treated him with the albendazole in which case the followed MRI showed that numbers of cystic lesions were copiously decreased. We report an unsual case of disseminated cysticercosis treated with medical therapy.

• The Journal of Korean Medicine
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• v.29 no.5
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• pp.118-125
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• 2008

Objective :Ginseng is one of the most popular Oriental medicinal plants considered as a tonic worldwide. This study aimed to produce comprehensive understanding for immune-related pharmaceutical activities of Ginseng. Methods: We surveyed all literatures, 168 of immunity-focused papers with Ginseng in Pub-med, and analyzed pharmaceutical characters according to immune elements and Ginseng components. Results : The main functions of Ginseng have been associated with modulation of immunity. Whole body of Ginseng or its ingredients differently show the effects on both cellular and humoral elements of immune system. Ginseng enhances the activities of T and B lymphocytes, NK cells, macrophages and dendritic cells whileas suppresses mast cell-associated allergy and release of histamine. Conclusion : These results will provide Korean doctors or scientists an immune-related overview of Ginseng, and help them in clinical applications and developments of Korean Ginseng as a global competitive drug in world market.

• Clinical and Experimental Pediatrics
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• v.53 no.9
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• pp.859-862
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• 2010

Transient magnetic resonance (MR) signal changes in the splenium of the corpus callosum (SCC) arise from many different conditions, including encephalopathy or encephalitis caused by infection, seizures, metabolic derangements, and asphyxia. Few case reports exist on reversible SCC lesions associated with rotavirus infection. A benign convulsion with mild gastroenteritis (CwG) is frequently associated with rotaviral infections. This entity is characterized by normal laboratory findings, electroencephalogram, neuroimaging, and good prognosis. We report a case of a 2.5-year-old Korean girl with rotavirus-associated CwG demonstrating a reversible SCC lesion on diffusion-weighted MR images. She developed 2 episodes of brief generalized tonic-clonic seizure with mild acute gastroenteritis without any other neurologic abnormality. Stool test for rotavirus antigen was positive. Brain MRI done on the day of admission showed a linear high signal intensity and decreased apparent diffusion coefficient values on the SCC. The lesion completely disappeared on follow-up MRI 6 days later. The patient fully recovered without any sequelae.

• Proceedings of the Ginseng society Conference
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• 1998.06a
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• pp.57-62
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• 1998

We hypothesized the primary effect of ginseng was to protect cell membrane fatty acids from decomposition caused by free radicals. To confirm the antioxidant effect of ginseng, we measured the inhibitory effect on the formation of thiobarbituric acid-reactive substances, an indicator of lipid peroxidation, and evaluated the free radical scavenging effect of ginseng by electron spin resonance spectrometer, and gas chromatography. The results showed that thiobarbituric acid-reactive substances formed and the loss of arachidonic acid during lipid peroxidation, and that hydroxyl (-like) radical peak formed by the iron complex (ferric nitrilotriacetate, an known free radical generator in vitro) were completely inhibited by ginseng extract. This antioxidant effect of ginseng may be responsible for its wide pharmacological actions in clinical practice. As the free radical reactions in general are rapid and non-specific, ginseng seems to act as a normalizer, rather than a general tonic, at the stages of acute or chronic active phase of the various diseases.