• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.13
• /
• pp.5427-5432
• /
• 2015

Background: Oral cancer stands among the 10 top causes of cancer death in the world. Considering the role of epidemiologic information on planning and effective interventions, the present study aimed to investigate the epidemiology of oral cancer in Iran. Materials and Methods: The required information for this systematic review study was obtained from PubMed, Google Scholar, CINAHL,SID, Medlib, Magiran and Iranmedex databases, using key words "cancer", "oral cancer", "squamous cell carcinoma", "oral cavity carcinoma" and their Persian equivalents in combination with keywords of epidemiology, prevalence, etiology, frequency, and Iran from 1990 to 2014. From 1,065 related studies found, finally 25 were included to the study. Results: The mean age of 8,248 patients in 25 studies was $54.0{\pm}15.1years$. The male/female ratio for oral cancer was 1.91. Tongue with average percentage of 29.9 was the most involved site. Regarding microscopic grade, 65.7% of cases were grade 1. SCCs, accounting for an average of 70.0%, was the most common among all types of oral cancer. In the majority of studies, smoking including cigarette, hookah, and tobacco consumption was found to be a risk factor. Conclusions: The epidemiological pattern of oral cancer in Iran is somewhat similar to that of other countries. Yet the information on hand in this field is limited and considering the role of epidemiological data we suggest conducting more accurate studies to catch data that is required for effective programs and interventions.

• Korean Journal of Microbiology
• /
• v.50 no.1
• /
• pp.67-72
• /
• 2014

Minimal broth containing nicotine as a sole carbon source (MB/N) was used to isolate novel nicotine-degrading bacterial strains from tobacco plants and field soils. Comparative analysis of 16S rRNA gene sequence, phenotypic test and morphological tests showed that the position of these isolates were in the genus Arthrobacter of the family Micrococcaceae. The highest 16S rRNA gene sequence similarity of the isolate NU11 and NU15 to type strains in the genus Arthrobacter were Arthrobacter equi (98.2%) which was presumably a novel strain and Arthrobacter nicotinovorans (99.8%), respectively. Both strain NU11 and NU15 showed rod shaped, Gram-positive characteristics and catalase activity, but did not show oxidase activity. The novel strain NU11 was found to degrade efficiently nicotine in MB/N medium by the analysis of UV absorption spectra and could be used as an organism in bioremediation technique.

• Korean Journal of Plant Tissue Culture
• /
• v.26 no.3
• /
• pp.177-182
• /
• 1999

A fungal infection assay between normal and transgenic potato harboring chitinase gene in cultivar Belchip was investigated. In the first stage of experiment, seven transgenic lines having 12cm tall were tested for their resistance against potato late blight pathogen Phytophthora infestans by infection with the zoospores, artificially, Susceptibility to potato late blight infection could be classified into three types based on the rate. In terms of resistance to the disease, two lines were higher, two lines were more suppressive, and three lines were similar as compared with the control. In the following experiment, only 2 risistant lines and 1 suppressed line were used to confirm the resistance again. The results of both experiments were similar. Furthermore, two highly resistant transgenic lines grown in field exhibited a higher resistance than control under the conditions of natural ocurrence of the fungal disease.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.29 no.4
• /
• pp.500-507
• /
• 2019

Objectives: The purpose of this study is to categorize farm types and analyze the cultivated area and labor input time for each crop over a year in order to decide farm type conducting for the hazard exposure assessment. Methods: Crops ranked within the top 45 by cultivated area in Korea were selected and 15 target crops that exposure assessment had been conducted for through the Rural Development Administration(RDA) pilot research projects were selected. Labor input time was based on data investigated through RDA research surveillance. If there was no data, data from Statistics Korea was used. Data from Statistics Korea was used for total cultivated area. Results: Crops were divided into 5 types: open field crops(Chinese cabbage, Corn, Ginger, Potato), fruits (Mandarin, Pear), green house crops(Cucumber, Lily, Oriental melon, Pumpkin, Tomato), livestock(Poultry), specialty crops(Ginseng, Oyster mushroom, Tobacco). The cultivated area for potato was the largest, and lily was the smallest among the crops. Labor input time over a year was the highest with oyster mushroom and the lowest with pear. Total labor input time by crops was the highest with mandarin and the lowest with Chinese cabbage. Conclusions: To evaluate hazard factors of farm work, it's essential that crops and tasks be classified based on the size of farmers and working hours by farm type. Therefore, the priority of management should be determined based on the cultivated area and total labor time, but the characteristics of tasks in each crop should also be considered.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.34 no.1
• /
• pp.40-47
• /
• 1989

To elucidate the relationship of the Quality of aromatic tobacco to their chemical constituents, certain chemical components and leaf Quality by price were compared among leaves produced, 1) under 4 different light intensities during maturing stage in field, 2) under 4 different temperature of 20$^{\circ}C$. 25$^{\circ}C$. 30$^{\circ}C$ and control of l8-22-28$^{\circ}C$ in phytotron. As the light intensity decreased chlorophyll content of harvested leaves increased, but specific leaf weight and Quality of cured leaves lowered. The content of sugar. pet. ether exts. and volatile organic acids decreased, but total nitrogen, nicotine, ash and pH increased as the .light intensity decreased. As the growth temperature increased days to flower was shortened and the growth was decreased without significant difference in leaf Quality. With higher growth temperature the content of nitrogen, ash and pH increased, but sugar decreased with no difference in pet. ether exts., volatile organic acids and volatile neutral content. Several Quality indices were disscussed for the Quality evaluation of aromatic leaves for two groups, respectively.

• Proceedings of the Botanical Society of Korea Conference
• /
• 1999.07a
• /
• pp.11-15
• /
• 1999

In order to evlauate feasibility of the gene tagging by the maize transposable element Ac in heterologous plant systems, we have investigated physical distances and directions of transposition of the element in Arabidopsis thaliana and tobacco cultured cell line BY-2. We prepared a T-DNA construct that carried a non-autonomous derivative of Ac with a site for cleavage by endonuclease I-Scel (designated dAc-I-RS element). Another cleavage site was also introduced into the T-DNA region outside dAc-I-RS. A number of transgenic Arabidopsis plants were generated, each of which had a single copy of the T-DNA at a different chromosomal location. To examine the pattern of transposition, three out of these transgenic plants were crossed with the Arabidopsis plant that carried the gene for Ac transposase and progeny in which dAc-I-RS had been transposed were isolated. After digestion of the genomic DNA of these progeny with I-SceI, sizes of segment of DNA were determined byd pulse-field gel electrophoresis. We also performed linkage analysis for the transposed elements and sites of mutations near the elements. Our results with three transgenic lines showed that 50% of all transposition events had occurred within 1,700 kilo-base pairs (kb) on the same chromosome, with 35% within 200 kb, and that the elements transposed in both directions on the chromosome with roughly equal probability. The data thus indicate that the Ac-Ds system is most useful for tagging of genes that are present within 200 kb of the chromosomal site of Ac in Arabidopsis. In addition, determination of the precise localization of the transposed dAc-I-RS element should definitely assist in map-based cloning of genes around insertion sites. In the present paper, we report typical examples of such gene isolation studies.

• Proceedings of the Botanical Society of Korea Conference
• /
• 1985.08b
• /
• pp.51-57
• /
• 1985

In order to evlauate feasibility of the gene tagging by the maize transposable element Ac in heterologous plant systems, we have investigated physical distances and directions of transposition of the element in Arabidopsis thaliana and tobacco cultured cell line BY-2. We prepared a T-DNA construct that carried a non-autonomous derivative of Ac with a site for cleavage by endonuclease I-Scel (designated dAc-I-RS element). Another cleavage site was also introduced into the T-DNA region outside dAc-I-RS. A number of transgenic Arabidopsis plants were generated, each of which had a single copy of the T-DNA at a different chromosomal location. To examine the pattern of transposition, three out of these transgenic plants were crossed with the Arabidopsis plant that carried the gene for Ac transposase and progeny in which dAc-I-RS had been transposed were isolated. After digestion of the genomic DNA of these progeny with I-SceI, sizes of segment of DNA were determined byd pulse-field gel electrophoresis. We also performed linkage analysis for the transposed elements and sites of mutations near the elements. Our results with three transgenic lines showed that 50% of all transposition events had occurred within 1, 700 kilo-base pairs (kb) on the same chromosome, with 35% within 200 kb, and that the elements transposed in both directions on the chromosome with roughly equal probability. The data thus indicate that the Ac-Ds system is most useful for tagging of genes that are present within 200 kb of the chromosomal site of Ac in Arabidopsis. In addition, determination of the precise localization of the transposed dAc-I-RS element should definitely assist in map-based cloning of genes around insertion sites. In the present paper, we report typical examples of such gene isolation studies.

• Journal of Haehwa Medicine
• /
• v.9 no.1
• /
• pp.711-724
• /
• 2000

I reached following conclusion through a bibliographic study about the drug dependence. 1. The drug dependence is the case that taking drugs continually in order to get around discomfort and get mental drug efficacy. that is also the state of poisoning that shows compulsions that using all means to get drugs. the drug dependence is coincident with alcolism in Oriental Medicine. 2 Medicinal matters that causes the drug dependence consist of two field. one is licit drugs, including a tranquilizer, a sleeping pill, anti-anxiety drug, alcohol, caffeine, tobacco, etc. the other is illict drugs, including opium products, psychostimulant, a hallucinogen, aromatic agent(adhesives, LSD, etc.) 3. Drugs that causes dependences has the habit which causing mental dependences and the medicinal poisining which causing physical dependences. 4. A syndrome of abstain from the drug which rides on all kinds of drugs is analogous to depressive psychosis, epilepsy, insanity, depressive syndromes, disorder of internal organs, histery, dizziness, etc. 5. The drug dependence causes visceral dysfunction, that is chiefly inflammatory lesion of brain, heart lung etc. (inflammatory lesions os mainly due to infect.) and injuries liver which removes toxic agents and kidney which is an excretory organ. 6. The treatment of the drug dependence, which needs at first check the medical record and the syndrome, is consist of the expectant treatment and isolating treatment as a rule and sometimes mental therapeutics is going on at the same time. 7. The oriental medical cure of the drug dependence needs more concrete study.

• Korean Journal of Environmental Agriculture
• /
• v.6 no.2
• /
• pp.12-21
• /
• 1987

Residues of some organo-chlorine pesticides on 108 solis collected from 5 sites of Chungnam avea during March 20-April 6, 1986 were investigated. 12 different kinds of Chemical components were detected showing the highest detection frequency with P.P'-DDE(67.6%) and the lowest with Heptachlor(1.8%). 4 different chemicals, ${\alpha}-BHC$, ${\gamma}-chlordane$, P.P'-DDD and P.P'-DDD and P.P'-DDE showed their average contents in the soils of 0.001 ppm and 0.005ppm for ${\beta}-BHC$, respectively. On the other hand, ${\alpha}-BHC$, ${\gamma}-chlordane$, P.P'-DDT. O.P'-DDT and P.P'-DDD showed 0.002ppm for their average contents of residues, respectively.

• Korean Journal of Environmental Agriculture
• /
• v.21 no.1
• /
• pp.24-30
• /
• 2002

Ginseng (Panax ginseng C. A. Meyer) has been cultivated on raised beds with shading condition for 4 to 6 years because of its physiological characteristics. This shading condition maintains relatively stable soil environments protecting from rainfall and direct sunlight. Therefore, pesticides in ginseng growing soil are exposed to far different environment from the general cropping field. To study the behavior of pesticides under this condition, the effect of covering on the persistency of Procymidone in ginseng cultivating soil was investigated by using several shade materials. The most important factor affecting Procymidone persistency in soil under covering was water leakage rates of shade materials.