• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.1
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• pp.105-125
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• 2024

Gliomas are the most common malignant brain tumor and cause the most deaths. Manual brain tumor segmentation is expensive, time-consuming, error-prone, and dependent on the radiologist's expertise and experience. Manual brain tumor segmentation outcomes by different radiologists for the same patient may differ. Thus, more robust, and dependable methods are needed. Medical imaging researchers produced numerous semi-automatic and fully automatic brain tumor segmentation algorithms using ML pipelines and accurate (handcrafted feature-based, etc.) or data-driven strategies. Current methods use CNN or handmade features such symmetry analysis, alignment-based features analysis, or textural qualities. CNN approaches provide unsupervised features, while manual features model domain knowledge. Cascaded algorithms may outperform feature-based or data-driven like CNN methods. A revolutionary cascaded strategy is presented that intelligently supplies CNN with past information from handmade feature-based ML algorithms. Each patient receives manual ground truth and four MRI modalities (T1, T1c, T2, and FLAIR). Handcrafted characteristics and deep learning are used to segment brain tumors in a Global Convolutional Neural Network (GCNN). The proposed GCNN architecture with two parallel CNNs, CSPathways CNN (CSPCNN) and MRI Pathways CNN (MRIPCNN), segmented BraTS brain tumors with high accuracy. The proposed model achieved a Dice score of 87% higher than the state of the art. This research could improve brain tumor segmentation, helping clinicians diagnose and treat patients.

• The Korean Journal of Pharmacology
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• v.31 no.3
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• pp.355-363
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• 1995

It has been well known that the intracellular calcium concentration $([Ca^{2+}]_i)$ in living cell is very sensitive to live or to survive, but the transmembrane system of calcium ion, especially mechanism of calcium ion movement in unexcitable state has been little elucidated. Though many proposed theories for calcium ion transport have been reported, it is still unclear that how could the sustained maintenance in cytosolic calcium level be done in cell. Since one of possible mechanisms of calcium transport may be related to the acetylcholine receptor-linked calcium channel, author performed experiment to elucidate this mechanism of calcium influx related to cholinergic receptor in ml muscarinic receptor-transfected RBL-2H3 cell-line. 1) The effects of carbachol both on calcium ion influx and on the secretion of hexosaminidase were respectively observed in the manner of time-related or concentration-dependent pattern in this model. 2) The effects of several metal cations on calcium transport were shown in carbachol-induced cell-line. 3) Atropine was administered to examine the relationship between cholinergic receptor and calcium ion influx in this model. 4) PMA (Phorbol 12-myristate 13-acetate) or PTx (Pertussis toxin) was respectively administered to examine the secondary mediator which involved pathway of calcium ion movement in carbachol-induced cell-line. The results of this experiments were as follows; 1) Carbachol significantly stimulated both the calcium influx and the secretion of hexosaminidase in the manner of the concentration-dependent pattern. 2) Atropine potently blocked the effects of carbachol in concentration-response manner. 3) Administered metal cations inhibited the calcium influx in carbachol-stimulated this model to the concentration-related pattern. 4) PMA did not inhibit carbachol-induced secretion of hexosaminidase, but blocked the calcium influx in this cell-line. 5) The suppression of carbachol-induced hexosaminidase secretion was shown in PTx-treated cell -line.

• 한국전산유체공학회:학술대회논문집
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• 2009.04a
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• pp.19-19
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• 2009

Dynamic Stall is a flow phenomenon which occurs on the retreating side of helicopter rotor blades during forward flight. It also occurs on blades of stall regulated wind turbines under yawing conditions as well as during gust loads. Time scales occurring during this process are comparable on both helicopter and wind turbine blades. Dynamic Stall limits the speed of the helicopter and its manoeuvrability and limits the amount of power production of wind turbines. Extensive numerical as well as experimental investigations have been carried out recently to get detailed insight into the very complex flow structures of the Dynamic Stall process. Numerical codes have to be based on the full equations, i.e. the Navier-Stokes equations to cover the scope of the problems involved: Time dependent flow, unsteady flow separation, vortex development and shedding, compressibility effects, turbulence, transition and 3D-effects, etc. have to be taken into account. In addition to the numerical treatment of the Dynamic Stall problem suitable wind tunnel experiments are inevitable. Comparisons of experimental data with calculated results show us the state of the art and validity of the CFD-codes and the necessity to further improve calculation procedures. In the present paper the phenomenon of Dynamic Stall will be discussed first. This discussion is followed by comparisons of some recently obtained experimental and numerical results for an oscillating helicopter airfoil under Dynamic Stall conditions. From the knowledge base of the Dynamic Stall Problems, the next step can be envisaged: to control Dynamic Stall. The present discussion will address two different Dynamic Stall control methodologies: the Nose-Droop concept and the application of Leading Edge Vortex Generators (LEVoG's) as examples of active and passive control devices. It will be shown that experimental results are available but CFD-data are only of limited comparison. A lot of future work has to be done in CFD-code development to fill this gap. Here mainly 3D-effects as well as improvements of both turbulence and transition modelling are of major concern.

• Journal of Advanced Navigation Technology
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• v.18 no.3
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• pp.254-260
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• 2014

We studied water level rising of drum versus time in the small hydraulic vertical water turbine system in this paper. The water level rises continuously up to a certain point with the passage of time if the constant incoming water is supplied, while it stops rising and maintains equilibrium state without any more rising because it increases position energy and evatually makes outgoing velocity and outgoing water quantities of runner area. The water level of drum is determined independent of size, height, width, figure of drum or runner configuration. It comes out that the water level is dependent only on the incoming and outgoing water quantities, and the output power has similar behavior. Therefore, desirable water level and output power are not available unless incoming water quantities is abundant. We validate this phenomina through applyng our methodolgies to the real small hydraulic vertical water turbine system under constructing and testing in industrial facilities in Korea.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.1
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• pp.93-99
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• 2014

This paper deals with the FC-MMA (Fast Convergence-Multi Modulus Algorithm) which is improving the convergence characteristics of the MMA (Multiple Modulus Algorithm) adaptive equalization algorithm that is used for the minimization of the intersymbol interference which occurs in the time dispersive communication channel. In the time varying charateristics and the abnormal situation like as outage of the communication channel, the adaptive equalizer needs to adapting the new environment more rapidly. For this problem, the residual isi and the maximum distortion performance index which are meaning the convergence characteristics are widely adapted in the adaptive equalizer. The 16-QAM signal is transmitted and it was confirmed that the proposed algorithm, the FC-MMA has the fast convergence performance such as in the 1.75 times fast in residual isi and 2.5 times fast in the maximum distortion in order to reaching the steady state compare to the MMA algorithm in the same channel environment by the computer simulation.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.3
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• pp.310-315
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• 2014

Cellular retinol-binding protein II (CRBP II) belongs to the family of cellular retinol-binding proteins and plays a major role in absorption, transport, and metabolism of vitamin A. In addition, because vitamin A is correlated with reproductive performance, we measured CRBP II mRNA abundance in erlang mountainous chickens by real-time PCR using the relative quantification method. The expression of CRBP II showed a tissue-specific pattern and egg production rate-dependent changes. The expression was very high (p<0.05) in jejunum and liver, intermediate in kidney, ovary, and oviduct, and lowest (p<0.05) in heart, hypothalamus, and pituitary. In the hypothalamus, oviduct, ovary, and pituitary, CRBP II mRNA abundance were correlated to egg production rate, which increased from 12 wk to 32 wk, peaked at 32 wk relative to the other time points, and then decreased from 32 wk to 45 wk. In contrast, the expression of CRBP II mRNA in heart, jejunum, kidney, and liver was not different at any of the ages evaluated in this study. These data may help to understand the genetic basis of vitamin A metabolism, and suggest that CRBP II may be a candidate gene to affect egg production traits in chickens.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.7A
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• pp.844-851
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• 2004

Various types of error are caused due to many factors of various environment in air interface channel of wireless communications. In this case, the reliability of the channel is much lower than that of wired case. IEEE 802.15.3 high-rate WPAN, which operates in an ad hoc networking environment, is more susceptible to such errors. The problem has been investigated for wireless LANs, for example, as follows. If the queue size of a certain node is longer than that of other nodes, the node estimates that its channel state is bad and the resource of the node is decreased. However this method has a disadvantage that a central controller must always monitor the status. To avoid this disadvantage, in this paper, a new MAC protocol that the throughput of overall piconet is increased by LDS (Link-status Dependent Scheduling) is proposed.

• Journal of the Korea Concrete Institute
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• v.18 no.4 s.94
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• pp.543-552
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• 2006

The current design for crack width control in concrete bridges is incomplete in analytical models. As one of the important serviceability limit states, the crack width be considered with the quantitative prediction of the initiation and propagation of corrosion and corrosion-induced cracking. A serviceability limit state of cracking can be affected by the combined effects of bond, slip, cracking, and corrosion of the reinforcing elements. Considering life span of concrete bridges, an improved prediction of crack width affected by time-dependent general corrosion has been proposed for the crack control design. The developed corrosion models and crack width prediction equation can be used for the design and the maintenance of prestressed and non-prestressed reinforcements by varying time, w/c, cover depth, and geometries of the sections. It can also be used as the rational criteria for the maintenance of existing concrete bridges and the prediction of remaining life of concrete structures.

• Tunnel and Underground Space
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• v.16 no.5 s.64
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• pp.413-421
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• 2006

In order to explain entirely dynamic fracture process induced by blasting in rock mass, it needs to consider detonation pressure and gas pressure acting on blasthole wall simultaneously. In this study, prior to simulating the coupling between gas flow and rock mass, we analyzed effects of gas pressure-time history, length of cracks and equation of state adopted to calculate the gas pressure on the gas flow within a radial fracture created by single-hole blasting. The effects were investigated on two assumptions: (a) the radial fracture was composed of 5 cracks which were 0.01 m in length and 0.001 m in asperity each and (b) the PETN explosive which diameter was 36 mm was charged in a blasthole of 45 mm diameter. It was concluded that the maximum gas pressure and its travel time were dependent on characteristics of charged explosives and geometrical properties of radial fracture.

• Korean Journal of Environmental Agriculture
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• v.3 no.1
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• pp.45-51
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• 1984

This study was performed to evaluate the aquatoxicity of 5 chemicals (butachlor, isoprothiolane, probenazole, carbofuran, and cartap) to carp (Cyprinus carpio), discuss the impact on the $96 hr-LC_{50}$ values of the chemicals with the exposure time. In butachlor, we also compared the acute toxicity values between two exposure system, the continuous flow system and static state system, and measured the dissolved oxygen concentrations in the two systems. The acute toxicity values (96 hr-LC50 values) of the 5 chemicals were 0.25 ppm in butachlor, 10.0 ppm in isoprothiolane, 6.2 ppm in probenazole, 1.40 ppm in carbofuran, and 0.64 ppm in cartap, respectively. We also found that the $LC_{50}$ values were downed with increase of the exposure time.