Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
권호 표지
DOI QR코드

DOI QR Code

Expression Profiles of Cellular Retinol-binding Protein, Type II (CRBP II) in Erlang Mountainous Chickens

  • Yin, H.D. (College of Animal Science and Technology, Sichuan Agricultural University) ;
  • Tian, K. (College of Animal Science and Technology, Sichuan Agricultural University) ;
  • Li, D.Y. (College of Animal Science and Technology, Sichuan Agricultural University) ;
  • Gilbert, E.R. (Department of Animal and Poultry Science, Virginia Polytechnic Institute and State University) ;
  • Xiao, L.H. (College of Animal Science and Technology, Sichuan Agricultural University) ;
  • Chen, S.Y. (Institute of Animal Genetics and Breeding, Sichuan Agricultural University) ;
  • Wang, Y. (Institute of Animal Genetics and Breeding, Sichuan Agricultural University) ;
  • Liu, Y.P. (College of Animal Science and Technology, Sichuan Agricultural University) ;
  • Zhao, X.L. (College of Animal Science and Technology, Sichuan Agricultural University) ;
  • Zhu, Q. (College of Animal Science and Technology, Sichuan Agricultural University)
  • Received : 2013.08.04
  • Accepted : 2013.11.22
  • Published : 2014.03.01
Download PDF
⟨ Previous Next ⟩

Abstract

Cellular retinol-binding protein II (CRBP II) belongs to the family of cellular retinol-binding proteins and plays a major role in absorption, transport, and metabolism of vitamin A. In addition, because vitamin A is correlated with reproductive performance, we measured CRBP II mRNA abundance in erlang mountainous chickens by real-time PCR using the relative quantification method. The expression of CRBP II showed a tissue-specific pattern and egg production rate-dependent changes. The expression was very high (p<0.05) in jejunum and liver, intermediate in kidney, ovary, and oviduct, and lowest (p<0.05) in heart, hypothalamus, and pituitary. In the hypothalamus, oviduct, ovary, and pituitary, CRBP II mRNA abundance were correlated to egg production rate, which increased from 12 wk to 32 wk, peaked at 32 wk relative to the other time points, and then decreased from 32 wk to 45 wk. In contrast, the expression of CRBP II mRNA in heart, jejunum, kidney, and liver was not different at any of the ages evaluated in this study. These data may help to understand the genetic basis of vitamin A metabolism, and suggest that CRBP II may be a candidate gene to affect egg production traits in chickens.

Keywords

References

  1. Ayers, K. L., A. H. Sinclair, and C. A. Smith. 2012. The molecular genetics of ovarian differentiation in the avian model. Sex. Dev. 7:80-94.
  2. Blaner, W. S., H. F. Hendriks, A. Brouwer, A. M. de Leeuw, D. L. Knook, and D. S. Goodman. 1985. Retinoids, retinoid-binding proteins, and retinyl palmitate hydrolase distributions in different types of rat liver cells. J. Lipid Res. 26:1241-1251.
  3. Cameron, M. C., E. M. Denovan-Wright, M. K. Sharma, and J. M. Wright. 2002. Cellular retinol-binding protein type II (CRBP II) in adult zebrafish (Danio rerio). Eur. J. Biochem. 269:4685-4692. https://doi.org/10.1046/j.1432-1033.2002.03170.x
  4. Crow, J. A. and D. E. Ong. 1985. Cell-specific immunohistochemical localization of a cellular retinol-binding protein (type two) in the small intestine of rat. Proc. Natl. Acad. Sci. USA. 82: 4707-4711. https://doi.org/10.1073/pnas.82.14.4707
  5. E, X. P., L. Zhang, J. Y. Lu, P. Tso, W. S. Blaner, M. S. Levin, and E. Li. 2002. Increased neonatal mortality in mice lacking cellular retinol-binding protein II. J. Biol. Chem. 277:36617-36623. https://doi.org/10.1074/jbc.M205519200
  6. Finlay, J. A. and H. F. DeLuca. 1988. Purification and properties of an 18-kilodalton, 1, 25-dihydroxyvitamin d3-modulated protein from embryonic chick intestine. Biochemistry 27: 3381-3387. https://doi.org/10.1021/bi00409a039
  7. Giguere, V. 1994. Retinoic acid receptors and cellular retinoid binding proteins: Complex interplay in retinoid signaling. Endocr. Rev. 15:61-79.
  8. Goda, T. and S. Takase. 1989. Purification, properties, and developmental changes of cellular retinol-binding protein, type II, in chicken intestine. J. Nutr. Sci. Vitaminol. 35:545-557. https://doi.org/10.3177/jnsv.35.545
  9. Gronemeyer, H. and R. Miturski. 2001. Molecular mechanisms of retinoid action. Cell. Mol. Biol. Lett. 6:3-52.
  10. Harrison, E. H. 2012. Mechanisms involved in the intestinal absorption of dietary vitamin a and provitamin a carotenoids. BBA-Mol. Cell. Biol. Lipids 1821:70-77. https://doi.org/10.1016/j.bbalip.2011.06.002
  11. Harrison, E. H. and M. M. Hussain. 2001. Mechanisms involved in the intestinal digestion and absorption of dietary vitamin A. J. Nutr. 131:1405-1408.
  12. Johnson, A. L. and D. C. Woods. 2009. Dynamics of avian ovarian follicle development: Cellular mechanisms of granulosa cell differentiation. Gen. Comp. Endocrinol. 163:12-17. https://doi.org/10.1016/j.ygcen.2008.11.012
  13. Lin, H., L. F. Wang, J. L. Song, Y. M. Xie, and Q. M. Yang. 2002. Effect of dietary supplemental levels of vitamin a on the egg production and immune responses of heat-stressed laying hens. Poult. Sci. 81:458-465. https://doi.org/10.1093/ps/81.4.458
  14. Liu, H. D. and E. Li. 1999. Influence of replenishing kidney herbs on osteoporosis induced by dexamethasone and retinoic acid in rats. Chin. J. Integr. Med. 5: 283-287.
  15. Livak, K. J. and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the $2^{-\Delta{\Delta}CT}$ method. Methods 25:402-408. https://doi.org/10.1006/meth.2001.1262
  16. Mark, M., N. B. Ghyselinck, and P. Chambon. 2009. Function of retinoic acid receptors during embryonic development. Nucl. Recept. Signal. 7:e002.
  17. Moran Jr, E. T. 2007. Nutrition of the developing embryo and hatchling. Poult. Sci. 86:1043-1049. https://doi.org/10.1093/ps/86.5.1043
  18. Napoli, J. L. 1996. Retinoic acid biosynthesis and metabolism. FASEB J. 10:993-1001.
  19. Oakley, O. R., M. L. Frazer, and C. Ko. 2011. Pituitary-ovary-spleen axis in ovulation. Trends Endocrinol. Metab. 22:345-352. https://doi.org/10.1016/j.tem.2011.04.005
  20. Oguntunji, A. O. and O. M. Alabi. 2010. Influence of high environmental temperature on egg production and shell quality: A review. World's Poult. Sci. J. 66:739-750. https://doi.org/10.1017/S004393391000070X
  21. Ong, D. E. 1984. A novel retinol-binding protein from rat. Purification and partial characterization. J. Biol. Chem. 259: 1476-1482.
  22. Ong, D. E. 1987. Cellular retinoid-binding proteins. Arch. Dermatol. 123:1693-1695. https://doi.org/10.1001/archderm.1987.01660360140026
  23. Ong, D. E. 1993. Retinoid metabolism during intestinal absorption. J. Nutr. 123:351-351.
  24. Ong, D. E. and D. L. Page. 1987. Cellular retinol-binding protein (type two) is abundant in human small intestine. J. Lipid Res. 28:739-745.
  25. Piantedosi, R., N. Ghyselinck, W. S. Blaner, and S. Vogel. 2005. Cellular retinol-binding protein type III is needed for retinoid incorporation into milk. J. Biol. Chem. 280:24286-24292. https://doi.org/10.1074/jbc.M503906200
  26. Schweigert, F. J. and H. Zucker. 1988. Concentrations of vitamin a, $\beta$-carotene and vitamin e in individual bovine follicles of different quality. J. Reprod. Fertil. 82:575-579. https://doi.org/10.1530/jrf.0.0820575
  27. Sundelin, J., U. Eriksson, H. Melhus, M. Nilsson, J. Lundvall, C. O. Bavik, E. Hansson, B. Laurent, and P. A. Peterson. 1985. Cellular retinoid binding proteins. Chem. Phys. Lipids 38: 175-185. https://doi.org/10.1016/0009-3084(85)90065-9
  28. Suruga, K., K. Mochizuki, M. Kitagawa, T. Goda, N. Horie, K. Takeishi, and S. Takase. 1999. Transcriptional regulation of cellular retinol-binding protein, type II gene expression in small intestine by dietary fat. Arch. Biochem. Biophys. 362: 159-166. https://doi.org/10.1006/abbi.1998.1018
  29. Takase, S., K. Suruga, R. Suzuki, and T. Goda. 1995. Relationship between perinatal appearance of cellular retinol-binding protein, type ii and retinal reductase activity in chick liver. Life Sci. 58:135-144. https://doi.org/10.1016/0024-3205(95)02266-X
  30. Wilson, H. R. 1997. Effects of maternal nutrition on hatchability. Poult. Sci. 76:134-143. https://doi.org/10.1093/ps/76.1.134
  31. Xiao, L. H., S. Y. Chen, X. L. Zhao, Q. Zhu, and Y. P. Liu. 2011. Association of cellular retinol-binding protein 2 (crbp2) gene polymorphism with egg production in erlang mountainous chicken. J. Poult. Sci. 48:162-167. https://doi.org/10.2141/jpsa.010099
  32. Yang, N. 2002. Poultry production Beijing: China Agriculture Press.
  33. Yin, H. D., Y. Wang, Z. C. Zhang, Y. P. Liu, S. Y. Chen, and Q. Zhu. 2013. Characterization of the expression profile and genetic polymorphism of the cellular retinol-binding protein (crbp iv) gene in erlang mountainous chickens. Int. J. Mol. Sci. 14:4432-4443. https://doi.org/10.3390/ijms14034432