• The Korean Journal of Nuclear Medicine
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• v.32 no.3
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• pp.266-275
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• 1998

Purpose: We measured pulmonary epithelial permeability by $^{99m}Tc-DTPA$ radioaerosol clearance in patients with diabetes and correlated with the presence of microangiopathy to understand the pathophysiology of pulmonary microangiopathy and evaluate $^{99m}Tc-DTPA$ radioaerosol clearance as a diagnostic test to assess pulmonary microangiopathy. Materials and Methods: We performed $^{99m}Tc-DTPA$ radioaerosol scan in 10 normal subjects, 10 asymptomatic smokers, 20 diabetic patients without history of smoking (10 with microangiopathy, 10 without microangiopathy). $^{99m}Tc-DTPA$ clearance half-time ($T_{1/2}$) was calculated, then compared with the result of chest radiography and pulmonary function test. Results: Chest radiography and pulmonary function test were normal in all subjects. There were no significant difference of clinical or laboratory characteristics between these groups except age. The diabetic patients with microangiopathy were significantly older (p<0.05). The $T_{1/2}$ of normal subjects and asymptomatic smokers were significantly different ($65.2{\pm}23.7min$ vs $39.6{\pm}9.8min$, p<0.05). For diabetic patients with microangiopathy, the $T_{1/2}$ was $90.5{\pm}46.5min$ and significantly delayed when compared with those of normals and asymptomatic smokers (p<0.05). However, the $T_{1/2}$ of diabetic patients without microangiopathy, $70.0{\pm}12.7min$, was not significantly different from those of normals or asymptomatic smokers (p>0.05). No significant correlation was found between the $T_{1/2}$ and spirometric parameters including DLco, FVC, $FEV_1,\;FEV_1/FVC$ (%) and $FEF_{25-75%}$ in all subjects, and between the $T_{1/2}$ and duration of diabetes ;in diabetic patients. Conclusion: Eventhough the influence of age can't be excluded, delayed $^{99m}Tc-DTPA$ clearance half-time ($T_{1/2}$) in diabetic patients with microangiopathy indicates decreased pulmonary capillary permeability as one of the pathophysiologic results of pulmonary microangiopaththy. Further studies are needed in larger number of age matched control and diabetic patients to evaluate the diagnostic efficacy.

• Journal of the korean academy of Pediatric Dentistry
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• v.30 no.3
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• pp.515-519
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• 2003

Supernumerary teeth are teeth added to the normal complement of teeth. They are most often found in the maxillary anterior region. Most supernumerary teeth in the maxillary anterior region have complications, such as impaction or malposition of permanent teeth, formation of diastema, cysts, and eruption into the nasal cavity or into the oral cavity. These complications have influence on deciding the treatment and its prognosis is depends on how these complications are treated. In clinical studies, it has been found that the removal of supernumerary teeth before the age of 5 years resulted in significant fewer eruption problems of the permanent tooth compared to removal at 7 years of age or later. However, such an early removal may leads to serious consequences of tooth development and behavioral management of patients. Therefore clinicians must consider complications of supernumerary tooth when deciding the time of removal. These cases report five-type of complication associated with supernumerary tooth such as diastema, delayed eruption, external root resorption, migration into nasal cavity and cyst formation.

• The Journal of the Korean bone and joint tumor society
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• v.15 no.2
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• pp.93-103
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• 2009

Purpose: We evaluated the outcomes of surgical reconstructions using recycled autograft augmented with VFG for bone defects caused by tumor resections. Materials and Methods: Ten patients with a malignant or locally aggressive bone tumor who were managed with recycled autograft augmented with VFG and followed up minimum 1 year were evaluated for bone union, functional result and complications. The influence of various factors on bone union and functional outcomes were also analyzed. Results: Bone unions were obtained at 13 of 20 junctions. Average union time was 3.7 months at metaphyseal junctions and 8 months at diaphyseal junctions (P<0.05). At diaphyseal junctions, younger aged group and intramedullary location group showed earlier bone union (P<0.05). The mean functional score was 81%. There were 3 nonunions, 4 delayed unions and 2 recycled bone resorption combined with fractures. Conclusion: To obtain excellent results, proper microvascular technique, sufficient length of VFG bridging both junctions, stable internal fixation and protection of reconstructed bone until union are necessary.

• The Journal of the Korea Contents Association
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• v.16 no.5
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• pp.242-250
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• 2016

This study was conducted to investigate whether Stroop-related cognitive task will be affected according to the preceding affective valence factored by matchedness in response time(RT) and whether facial recognition will be indexed by specific event-related potentials(ERPs) signature in normal person as in patients suffering from affective disorder. ERPs primed by subliminal(30ms) facial stimuli were recorded when presented with four pairs of affect(positive or negative) and cognitive task(matched or mismatched) to get ERP effects(N2 and P300) in terms of its amplitude and peak latency variations. Behavioral response analysis based on RTs confirmed that subliminal affective stimuli primed the target processing in all affective condition except for the neutral stimulus. Additional results for the ERPs performed in the negative affect with mismatched condition reached significance of emotional-face specificity named N2 showing more amplitude and delayed peak latency compared to the positive counterpart. Furthermore the condition shows more positive amplitude and earlier peak latency of P300 effect denoting cognitive closure than the corresponding positive affect condition. These results are suggested to reflect that negative affect stimulus in subliminal level is automatically inhibited such that this effect had influence on accelerating detection of the affect and facilitating response allowing adequate reallocation of attentional resources. The functional and cognitive significance with these findings was implied in terms of subliminal effect and affect-related recognition modulating the cognitive tasks.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.6
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• pp.698-707
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• 2019

The removal of oil spilled by the sinking of a foreign ship in Korea's Exclusive Economic Zone (EEZ) began in May 2019 four years after the ship sunk near Jeju Island. The cleanup was conducted by a foreign company that was contracted to the ship-owner's protection & indemnity (P&I) insurance company. In contrast to the time taken to begin the cleanup, the operation itself was completed in just 22days. Compared to similar cases, the decision to begin the removal was a delayed one. This study analyzes all 93 documents related to the ship's sinking and the eventual cleanup, confirming delays in administrative decision-making on the removal, and identifies factors that influenced this delay. These factors include a neglect of accident-related data verification, and other, legal, technical, environmental, and human aspects. Finally, this study suggests ways to improve decision-making efficiency. As the first study dealing with the cleanup in the EEZ, this research is expected to facilitate decision-making and influence the formulation of policies in the future.

• Korean Journal of Social Welfare
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• v.57 no.2
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• pp.375-403
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• 2005

This Study reviews theoretical argument about the effect of retirement earnings test on the labor supply of the aged which is controversial issue in OECD countries and analyze the effect on the incidence of re-employment, re-employment period of suspended officials and the possibility of re-retirement through Government Employment Pension Corporation data. It consists of 178,363 public officials who received pension benefit or disability pension in January 2005. The main result of this research shows that public officials re-employed were 8,086 which is 4.5% of total retired, and median survival time of suspended pension payments is 3.3 years. Also the median re-employment period of 100% suspended officials is about 20 month shorter than that of 1/2 suspended officials and it is shown in regression analysis that the possibility of re-retirement by 100% suspended officials is statistically significant higher than those of 50%. It specially expects greater influence if includes in case taking lump-sum or no making effect of re-employment because current system withhold pension payments even by earned income itself. Therefore, this analysis suggests suspension of pension payment properly applied according to the age and income together with "Delayed Retirement Credit" or "Partial Pension" for developmental alternatives of civil servant's suspension of pension payments. Furthermore, It is urgently needed that distinctive quality data about re-employment including earnings to perform deep-empirical research for effective policy. Lastly, it is extremely necessary to reinforce management system of Government Employment Pension Corporation.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.4
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• pp.485-492
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• 2011

The influence of high temperature on mammary cell turnover during the dry period is still unclear. The objective of this study was to investigate mammary cell turnover and p53 protein expression in the mammary tissue under high temperature conditions. Mammary gland biopsy samples from 8 dairy cows were obtained at 7, 25, 40, and 53 d during the dry period in summer or spring (n = 4, each season). Cell cycle, cell turnover, and p53 protein expression were analyzed by flow cytometry. During the dry period in summer, the percentage of mammary epithelial cells in the G0/G1 phase was the highest, but those in the S and G2/M phases were lower. However, the proportion of cells in the different stages of the cell cycle was not significantly different among the different biopsy time points, except in the G2/M phase. Under different temperature conditions, the cells were significantly different in their apoptotic rate and proliferation index; moreover, the tendencies of these indicators to change significantly differed. In general, the samples under high temperature conditions showed significantly lower apoptotic rates and proliferation indices. Under high temperature conditions, the apoptotic rate and proliferation index were the lowest (2.17% and 3.26%, respectively) at day 40, and the highest at day 53 (3.67% and 4.61%, respectively). However, under normal temperature conditions, the values of these indicators were the lowest (7.60% and 5.54%, respectively) at day 7, and almost the highest at day 25 (12.85% and 6.47%, respectively). Moreover, p53 protein expression was significantly higher under high temperature conditions than under normal temperature conditions, except at day 25. The level of p53 protein was the lowest (13.10%) under high temperature conditions at day 25, but was the highest (26.07%) under normal temperature conditions. Our findings suggest that high temperature delayed the G2/M phase of the cell cycle and the cell turnover rate, but remarkably increased p53 protein expression. Thus, the results indicate that high temperature extends the recovery period of mammary epithelial cells.

• Korean Journal of Agricultural Science
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• v.15 no.1
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• pp.36-46
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• 1988

Twelve soybean cultivars were cultivated in the 1/2,000a. Wagner pots with irrigation and without irrigation for 30 days after flowering, and the differences of plant growth and bean yield among cultivars were compared. And to investigate the varietal differences in the rate of photosynthesis under different relative humidity, 6soybean cultivars were cultivated in 1/2,000a. Wagner pot and the rate of photosynthesis of each soybean cultivar at flowering time was measured under the relative humidity of 80, 70, 60, 50 and 40%. The results obtained are summarized as follows; 1. The days to maturity of the soybean cultivars were shortened by non-irrigation treatment. The response of the maturing dates to non-irrigation was significantly different among the soybean cultivars. The days for maturing of Paldal, Danyeob and Eundaedu were delayed 2 days but those of Jangbaek and Tamahomare were delayed about 7 to 8 days under non-irrigation treatment. 2. The stem length, stem diameter, number of nodes of the mainstem, number of branches and number of branch nodes of all soybean cultivars were decreased by non-irrigation treatment. The number of branches and the number of branch nodes were especially severely influenced by non-irrigation treatment. 3. The number of pods per plant and the number of perfect pods was significantly reduced by non-irrigation treatment but the number of imperfect pods was increased. The non-irrigation treatment reduced the number of pods per plant by 58.0% and the ratio of the number of the perfect pods per plant by 46.6% relative to the ordinary cultivation with irrigation. 4. The grain yield of all cultivars was significantly reduced by the non-irrigation treatment, and average grain yield of soybean cultivars cultivated under non-irrigation treatment was 35.9% of that of soybean cultivars cultivated with irrigation. The influence of non-irrigation treatment was lowest in Paldal and significantly high in Tamahomare and Jangbaek. 5. The rate of photosynthesis of soybean leaves was significantly different among cultivars and was also influenced by relative humidity. Ratio of the photosynthetic amount of soybean leaves at 40% RH to the maximum photosynthesis at optimal humidity was 97.2% in Paldal, 96.4% in Danyeob and 88.8% in Baekun. 6. At 40% relative air humidity, highly significant correlations were found among the photosynthesis rate, the amount of transpiration and the respiration rate.

• Current Research on Agriculture and Life Sciences
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• v.9
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• pp.147-155
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• 1991

Effects of harvest date, number of the leaves remained on stump after flower cutting, duration of cold treatment on the growth and flowering of L. elegans 'Connecticut King' bulb were tested. Shoot emerging rate increased over 90% by delayed cold treatment, late harvesting time and more leaves remained. Flowering rate increased over 90% when conducted cold treatment of 90 days to the premature bulb at flowering date, the bulb matured for 50 days with 10 leaves and the bulb matured for over 30 days with 20 leaves, and when conducted cold treatment of 50 days to the bulb matured for over 30 days with all leaves. Delayed cold treatment duration shortened days needed to shoot emergence and flowering. Especially days to flower of the premature bulb at flowering date were the shortest of all treatments, and can be flowered within 100 days after planting. In generally, plant height, number of flowers per plant and stem diameter generally increased by longer bulb maturing period after flower cuting, and the premature bulb harvested at flowering date showed poor growing and flowering responses. But, if used the larger size bulb, it is believed that the prematured bulb can be forced to flower normally in current year without bulb maturing period.

• The Journal of the Korean Society for Microbiology
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• v.16 no.1
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• pp.49-55
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• 1981

Recent studies have demonstrated that histamine could have a modulatory influence on the immune response in vitro and in vivo. However, the effect of histamine on immune response in mice has not been extensivley analyzed. In the present study the regulatory effects of cimetidine, a histamine-2-receptor antagonist(H2 blocker) and histamine on the immune response to sheep red blood cells(SRBC) were evaluated in mice. Mice pretreated with daily intraperitoneal injection of varying concentrations of cimetidine for 14 days were immunized intraperitoneally with various concentrations of SRBC($10^6,\;10^7,\;and\;10^8$ cells) and challenged 4 days post immunization. The cellular immune response was determined by measuring the footpad swelling reaction. Footpad swelling reaction of each mouse was measured at 3hr(Arthus) reaction) and 24 or 48 hr(delayed reactions) after challenge. The humoral immune response was determined by measuring hemagglutinins to SRBC. Histamine in varying concentrations($10^{-1},\;10^{-3}\;and\;10^{-5}M$(was added in SRBC suspension at the time of antigen challenge into footpad, and 24-hr delayed type hypersensitivity(DTH) was measured. Cimetidine in varying concentrations(10, 50, 250, 1250 and 6250${\mu}g$) enhanced 24-hr DTH and this enhancement of DTH was more pronounced at 250${\mu}g$ of cimetidine. However, there were no significant differences between the cimetidine-pretreated groups and controls in Arthus reaction and hemagglutinin titers. Histamine suppressed the DTH in the dose-dependent fashion. This suppression was more pronounced at lower concentration of immunizing antigen($10^7\;and\;10^6$ SRBC). However, histamine did not diminish the DTH at higher concentration of antigen($10^8$ SRBC). These results present the evidences which strongly suggest that cimetidine enhances the cell-mediated immune response but not significantlly influences the humoral immune response and that exogenous and endogenous histamine is involved in the modulation of cellular immune response as well as immediate hypersensitivity.