• Proceedings of the KSME Conference
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• 2001.11b
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• pp.59-64
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• 2001

The fluid flow, mass transfer and film thickness variation during a wafer spin coating process are numerically studied. Governing equations for the cylindrical coordinates are simplified using the similarity transformation and solved efficiently using the finite difference method. Concentration dependent viscosity and the binary diffusivity of the coating liquid are used in the analysis. The time variational velocity components of the coating liquid and the film thickness are analyzed according to the various spin speed. When the evaporation is considered, the flow decease in the early times due to the increase of the viscosity and the resultant flow resistance. Effects of the two film thinning mechanism, the flow-out and evaporation are also considered in the analysis.

• Wind and Structures
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• v.4 no.3
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• pp.227-246
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• 2001

The objective of this study is to understand the flow above the front edge of low-rise building roofs. The greatest suction on the building is known to occur at this location as a result of the formation of conical vortices in the separated flow zone. It is expected that the relationship between this suction and upstream flow conditions can be better understood through the analysis of the vortex flow mechanism. Experimental measurements were used, along with predictions from numerical simulations of delta wing vortex flows, to develop a model of the pressure field within and beneath the conical vortex. The model accounts for the change in vortex suction with wind angle, and includes a parameter indicating the strength of the vortex. The model can be applied to both mean and time dependent surface pressures, and is validated in a companion paper.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.14 no.7
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• pp.599-606
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• 2002

uniform temperature. The surfaces of the block are taken at a constant higher temperature. The channel walls are assumed to be adiabatic. Results on the time-dependent temperature field are obtained and averaged over a cycle of pulsation. The effect of the important governing parameters, such as the Strouhal number on the flow and the heat transfer is investigated in detail. The results indicate that the recirculating flow behind the block are substantially affected by the pulsation frequency. These, in turn, have a strong influence on the thermal transport from the heated element to the pulsating flow. The frequency at which the enhancement is maximum is determined.

• Journal of Dental Rehabilitation and Applied Science
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• v.23 no.2
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• pp.179-186
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• 2007

The decrease of masticatory function caused by tooth loss leads to a decrease of cerebral blood flow volume resulting in impairment of cognitive function and learning memory disorder. However, the reduced mastication-mediated morphological alteration in the central nervous system (CNS) responsible for senile deficit of cognition, learning and memory has not been well documented. In this study, the effect of the loss of the molar teeth (molarless condition) on the hippocampal expression of glial fibrillary acidic protein (GFAP) protein was studied by immunohistochemical techniques. The results were as follows : 1. The molarless mice showed a lower density of pyramidal cells in the cornu ammonis 1 (CA1) and dentate gyrus (DG) region of the hippocampus than control mice. 2. Immunohistochemical analysis showed that the molarless condition enhanced the time-dependent increase in the cell density and hypertrophy of GFAP immunoreactivity in the CA1 region of the hippocampus. The molarless condition enhanced an time-dependent decrease in the number of neurons in the hippocampal formation and the time-dependent increase in the number and hypertrophy of GFAP-labeled cells in the same region. The data suggest a possible link between reduced mastication and histological changes in hippocampal formation that may be one risk factor for senile impairment of cognitive function and spatial learning memory.

• Transactions of Materials Processing
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• v.25 no.6
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• pp.359-365
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• 2016

The rate-controlling mechanisms for time-dependent plastic deformation of eutectoid and hyper-eutectoid pearlitic steels at low $T/T_m$ temperatures were explored. The strain rate - stress data obtained from a series of constant load tensile tests at $0.25{\sim}0.30T/T_m$ were applied to the power law, the lattice friction controlled plasticity, and the obstacle controlled plasticity. Of these models, the obstacle controlled plasticity was found to best-describe the rate-controlling mechanism for time-dependent plastic deformation of two steels at low $T/T_m$ temperatures in terms of the activation energy for overcoming the obstacles against dislocation glide in ferrite. The deformed microstructures revealed the dislocation forests of a high density as the main obstacles. In addition, the obstacle controlled plasticity well-explained the effects of cementite on the $0^{\circ}K$ flow stress of two steels.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.5055-5061
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• 2014

In this study, an anti-oxidant and anti-tumor protein Latcripin-3 of Lentinula edodes C91-3 was expressed in Escherichia coli. for the first time. According to the cDNA library, the full-length gene of Latcripin-3 was cloned by the methods of 3'-full rapid amplification of cDNA Ends (RACE) and 5'-full RACE. The structural domain gene of Latcripin-3 was inserted into the pET32 a(+). The functional protein of Latcripin-3 was expressed in Rosetta-gami (DE3) E. coli, evaluated by Western blotting and mass spectrometry. DPPH testing showed that the protein Latcripin-3 can scavenge free radicals remarkably well. The activity of functional protein Latcripin-3 on A549 cells was studied with flow cytometry and the MTT method. The MTT assay results showed that there was a decreases in cell viability in a dose-dependent and time-dependent manner in protein Latcripin-3 treated groups. Flow cytometry demonstrated that Latcripin-3 can induce apoptosis and block S phase dramatically in human A549 lung cancer cells as compared to the control group. At the same time, the cell ultrastructure observed by transmission electron microscopy supported the results of flow cytometry. This research offers new insights and advantages for identifying anti-oxidant and anti-tumor proteins.

• Journal of Astronomy and Space Sciences
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• v.4 no.1
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• pp.11-23
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• 1987

In dward nova we assume the primary star as a white dwarf and the secondary as the late type star which filled Roche lobe. Mass flow from the secondary star leads to the formation of thin accretion disk around the white dwarf. We use the $\alpha$ parameter as viscosity to maintain the disk form and propose that the outburst in dwarf nova cause the step increase of source term. With these assumptions we solve the basic equations of stellar structure using New-Raphson method. We show the physical parameters like temperature, density, pressure, opacity, surface density, height and flux to the radius of disk. Changing the value of $\alpha$, we compare several parameters when mass flow rate is constant with those of when luminosity of disk is brightest. At the same time, we obtain time-dependent variations of luminosity and mass of disk. We propose the suitable range of $\alpha$is 0.15-0.18 to the difference of luminosity. We compare several parameters of disk with those of the normal late type stars which have the same molecular weight of disk. These show the temperature and pressure of disk are similar to those of normal stars but the density of disk is lower. Maybe the outburst in dwarf nova is due to the variation of the $\alpha$ value instead of increment of mass flow from the secondary star.

• Proceedings of the KSME Conference
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• 2001.11b
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• pp.676-681
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• 2001

In this paper, the spin-up from rest to a state of solid-body rotation in a circular container with a slender rectangular obstacle on the bottom wall is analysed experimentally. We use a PIV method for the evolution of the free-surface flow. Laboratory experiments have been carried out for a variety of the obstacle height h(0, 5, 10 [mm]) and the liquid depth H(25, 50, 75, 100 [mm]). It was found that the spin-up time is crucially dependent on the obstacle height T. In the case of T=10[mm] the spin-up time is considerably shorter then the other cases.

• Coupled systems mechanics
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• v.1 no.4
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• pp.361-379
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• 2012

This paper presents a fully coupled three-dimensional solver for the analysis of interaction between pulsatile flow and large deformation structure. A partitioned time marching algorithm is employed for the solution of the time dependent coupled discretised problem, enabling the use of highly developed, robust and well-tested solvers for each field. Conservative transfer of information at the fluid-structure interface is combined with an effective multi-predict-correct iterative scheme to enable implicit coupling of the interacting fields at each time increment. The three-dimensional unsteady incompressible fluid is solved using a powerful implicit time stepping technique and an ALE formulation for moving boundaries with second-order time accurate is used. A full spectrum of total variational diminishing (TVD) schemes in unstructured grids is allowed implementation for the advection terms and finite element shape functions are used to evaluate the solution and its variation within mesh elements. A finite element dynamic analysis of the highly deformable structure is carried out with a numerical strategy combining the implicit Newmark time integration algorithm with a Newton-Raphson second-order optimisation method. The proposed model is used to predict the wave flow fields of a particular flow-induced vibrational phenomenon, and comparison of the numerical results with available experimental data validates the methodology and assesses its accuracy. Another test case about three-dimensional biomedical model with pulsatile inflow is presented to benchmark the algorithm and to demonstrate the potential applications of this method.

• The Korean Journal of Physiology and Pharmacology
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• v.4 no.3
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• pp.253-261
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• 2000

Head-out water immersion induces marked increase in the cardiac stroke volume. The present study was undertaken to characterize the stroke volume change by analyzing the aortic blood flow and left ventricular systolic time intervals. Ten men rested on a siting position in the air and in the water at $34.5^{circ}C$ for 30 min each. Their stroke volume, heart rate, ventricular systolic time intervals, and aortic blood flow indices were assessed by impedance cardiography. During immersion, the stroke volume increased 56%, with a slight (4%) decrease in heart rate, thus cardiac output increased ${\sim}50%.$ The slight increase in R-R interval was due to an equivalent increase in the systolic and diastolic time intervals. The ventricular ejection time was 20% increased, and this was mainly due to a decrease in pre-ejection period (28%). The mean arterial pressure increased 5 mmHg, indicating that the cardiac afterload was slightly elevated by immersion. The left ventricular end-diastolic volume index increased 24%, indicating that the cardiac preload was markedly elevated during immersion. The mean velocity and the indices of peak velocity and peak acceleration of aortic blood flow were all increased by ${\sim}30%,$ indicating that the left ventricular contractile force was enhanced by immersion. These results suggest that the increase in stroke volume during immersion is characterized by an increase in ventricular ejection time and aortic blood flow velocity, which may be primarily attributed to the increased cardiac preload and the muscle length-dependent increase in myocardial contractile force.