• Journal of the Korean Society of Safety
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• v.26 no.5
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• pp.1-6
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• 2011

Flame extinction and the chemistry of stoichiometric methane/air mixture were investigated numerically in the PSR(perfectly stirred reactor). For the study, PSR code was modified to be possible to unsteady calculation, and the sinusoidal fluctuation was subjected to the residence time. In the region of residence time far from the extinction limit, combustion mode was strongly dependent on the frequency. The low frequency excitation provided the quasi-steady behavior on the temperature and the concentrations of related species, but small variation of temperature was observed under high frequency. In the region of residence time near the extinction limit, the mixture subjected above 1 KHz was still reacting even though extinction had to be occurred under quasi-steady concept. The attenuation of extinction limit resulted from that chemical time was comparable to the flow time. The mean mole fractions of both NO and CO were almost same regardless of imposed frequency. However, the average mole fraction of $C_2H_2$ was decreased as increasing frequency, which implies that soot yield might be reduced at the higher frequency of flow excitation. The result provides the basic concept for flame stabilization, and it will be used to design a mild combustor.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.745-755
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• 2002

To examine the effects of Yunpyesan on the cell proliferation of A549 human lung carcinoma cell line, we performed various experiments such as dose-dependent effect of Yunpyesan on cell proliferation and viability, morphological changes, quantification of apoptotic cell death and alterations of apoptosis/cell cycle-regulatory gene products. Yunpyesan declined cell viability and proliferation in both a dose- and a time-dependent manner. The anti-proliferative effect by Yunpyesan treatment in A459 cells was associated with morphological changes such as membrane shrinking and cell rounding up. Yunpyesan Induced apoptotic cell death in a time-dependent manner, which was associated with degradation of poly-(ADP-ribose) polymerase (PARP), an apoptotic target protein, without alterations of the balance between Bcl-2 and Bax expressions. DNA flow cytometric histograms showed that population of G1 phase of the cell cycle was increased by Yunpyesan treatment in a dose-dependent manner. Western blot analysis revealed that cyclin D1 and A were reduced by Yunpyesan treatment, whereas cyclin dependent kinase (Cdk) inhibitor p27 was markedly increased in a time-dependent fashion. The level of tumor suppressor p53 proteins was also increased by Yunpyesan treatment and its increase might be linked to increase of Cdk inhibitor p27. In addition, Mdm2, negative regulator of p53, was down-regulated by Yunpyesan treatment. Since the expression of retinoblastome protein (pRB), a key regulator of G1/S progression, was reduced by Yunpyesan treatment, we supposed that phosphorylation of pRB might be also blocked. The present results indicated that Yunpyesan-induced inhibition of lung cancer cell proliferation is associated with the induction of apoptosis and the blockage of G1/S progression.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.21 no.7
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• pp.919-927
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• 1997

The main purpose of this study is to determine bifurcation as the primary instability of a glass melting furnace. Steady-state and unsteady characteristics of natural convection in the partially open cavity as appeared in a glass melting furnace is investigated by using numerical analysis. Three types of convection, such as steady laminar, unsteady periodic or unsteady quasi-periodic convection may occur according to the temperature difference between upper two isothermal surfaces along the depth of cavity in a glass melting furnace. In the temperature difference of 150-900 K between batch and free surface, the larger the temperature difference, the weaker the convection strength and unsteadiness. Since the glass viscosity is increasing exponentially in the lower temperature, the batch freezes the thermofluidic field especially below the surface of it. If the depth of cavity is 0.5 m, the bifurcation to time-dependent natural convection may occur in the range of 60-650 K. If that is 1.0 m, it may occur in the whole range of temperature difference.

• International Journal of Aeronautical and Space Sciences
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• v.18 no.1
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• pp.38-47
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• 2017

This paper presents experimental data on water droplet breakup in high-speed air flows. Exact-time-dependent evolution of wave and droplet interaction as well as breakup processes were optically visualized using a shadowgraph technique. Droplet experiments were conducted in a shock tube. Five flow conditions were used with an incident shock wave Mach number from 1.40 to 2.19 with Weber number based on the droplet initial diameter from 2300 to 38000, respectively. This corresponds to post-shock flow speeds varying from subsonic to supersonic. The considered droplet diameters were 2.0 mm to 3.6 mm. Some interesting wave patterns in the near wake were found. The present data shows that with an increase in the Weber number the droplet acceleration coefficient decreases and the level of decrease was weaker for the case of higher Mach numbers. This state of affair is different to the existing data in literature. Possible reasons are discussed.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.30 no.11 s.254
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• pp.1101-1106
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• 2006

To investigate a relation between fine scale eddies and particle dispersion in a near-wall turbulence, direct numerical simulations of turbulent channel flow laden particle are performed for $Re_{\tau}$=180. The motions of 0,8 million particles are calculated for several particle response times ($t_p$) which is the particle response time based on stokes’ friction law. The number density of particles has a tendency to increase with approaching the near-wall regions ($y^+$<20) except for cases of very small and large particle response times (i.e. $t_p$=0.02 and 15). Near the wall, the behavior and distribution of particles are deeply associated with the fine scale eddies, and are dependent on particle response times and a distance from the wall. The Stokes number that causes preferential distribution in turbulence is changed by a distance from the wall. The influential Stokes number based on the Burgers' vortex model is derived by using the time scale of the fine scale eddies. The influential Stokes number is also dependent on a distance from the wall and shows large value in the buffer layer.

• Biotechnology and Bioprocess Engineering:BBE
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• v.10 no.4
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• pp.341-345
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• 2005

Since it is troublesome to estimate adequate flow rates in four sections of SMB chromatography, a systematic determination of the flow rates has been suggested by using ketoprofen as a model chiral enantiomer. S-ketoprofen. less retained species, was separated from raffinate stream and the variation in its purity was dependent on the changes of the flow rate of section 4 ($Q_4$), the raffinate flow rate ($Q_{raf}$), and the feed flow rate ($Q_{feed}$) under a fixed switch­ing time t$^{\ast}$. When one parameter was changed at the given experimental condition, purities of product were changed and these phenomena has be well explained by the triangle theory.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.10 s.241
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• pp.1130-1138
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• 2005

A national standard system for the petroleum field has been developed to calibrate and test the oil flow meters in Korea. The operating system and the uncertainty of the system were evaluated by the peer reviewers of foreign national metrology institutes in 2002. Since the characteristics of the system might be changed by time, the uncertainty of the system is reevaluated with the consideration of the long term stability of the system. It is found that the system has a relative expanded uncertainty of 0.048 $\%$ in the range of $15\~120\;m^3/h$. According to the uncertainty budget, the uncertainties of the fluid density and the final mass measurement, which are temperature dependent, contribute about $94\%$ of the total uncertainty in the oil flow standard system

• International Journal of Aeronautical and Space Sciences
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• v.15 no.3
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• pp.232-240
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• 2014

Transonic flow past a NASA SC(2)-0710 airfoil with deployments of a spoiler up to $6^{\circ}$ was studied numerically. We consider angles of attack from $-0.6^{\circ}$ to $0.6^{\circ}$ and free-stream Mach numbers from 0.81 to 0.86. Solutions of the unsteady Reynolds-averaged Navier-Stokes equations were obtained with a finite-volume solver using several turbulence models. Both stationary and time-dependent deployments of the spoiler were examined. The study revealed the existence of narrow bands of the Mach number, angle of attack, and spoiler deflection angle, in which the flow was extremely sensitive to small perturbations. Simulations of 3D flow past a swept wing confirmed the flow sensitivity to small perturbations of boundary conditions.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.743-746
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• 2002

Experimental investigation of the flow field of supersonic cavity is described. In this research, supersonic cavity is used in chemical laser system. For efficient laser, downstream flow after cavity need to be uniform and clear for pressure recovery system. In previous research, it's known that there's oscillation In cavity and is due to Mach number and L/D ratio. A strong recompression occurs at the after wall and the flow is visibly unsteady. Cavity flow in this research is of the open type, that is, length-to-depth ratio $L/D<10\;at\;M\;=\;3$. Experiment is done with pressure measurement by piezo-type sensor and visualization by Schlirern method. The time-dependent experimental result is compared with computation.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.12 s.243
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• pp.1344-1351
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• 2005

Three-dimensional, time-dependent solutions of fluid flow past a circular cylinder with a periodic array of circular fins are obtained using an accurate and efficient spectral multidomain methodology. A Fourier expansion with a corresponding uniform grid is used along the circumferential direction. A spectral multidomain method with Chebyshev collocation is used along the r-z plane to handle the periodic array of circular fins attached to the surface of the cylinder. Unlike the flow past a circular cylinder, Second instabilities like mode A and mode B are not found in the Reynolds number range $100\~500$. It is found that three-dimensional instability of vortical structures is suppressed due to the presence of fin. The present numerical solutions report the detailed information of flow quantities near wake of finned cylinder.