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Usefulness evaluation of Hybrid planning through dosimetric comparision of Three Dimensinal Conformal Radiation Radiotherapy and Hybrid planning for left breast cancer (유방암 환자의 방사선 치료시 Energy와 Wedge를 combine한 Hybrid plan의 유용성 평가)

  • Chae, Moon Ki;Park, Byung Soo;Ahn, Jong Ho;Song, Ki Won
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.1
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    • pp.91-98
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    • 2014
  • Purpose : To compare the dosimetry for the left breast cancer treatment between three dimensional conformal radiation radiotherapy (3D-CRT) and Hybrid planning and to estimate usefulness of Hybrid planning Materials and Methods : Five patients with left breast cancer were included in the study. They were planned using several different radiotherapy techniques including: 1)open rectangular field, 2)tangential wedge-based field 3)field in field, 4)hybrid planning(energy, wedge combine). For each patient planning was using Light Speed RT-16 CT and PINNACLE planning system-ver.9.2. Hybrid plan was made using same system and using the same targets and optimization goals. We comparing the Homogeneity Index(HI), normal organs at the does-volume histogram(DVH) Results : In all plans, the Homogeneity Index(HI) of Hybrid planning was significantly better than other. Dose comparison of HI= 2D-RT:38.32, TW:38.32, FIF:29.22, HYBRID:30.57. 2D-RT, TW, FIF Hybrid$V_{75_-lung}$=112.33, 125.14, 121.3, 123.78. $V_{50_-lung}$=155.43, 159.62, 157.96, 159.06. $V_{25_-lung}$=199.86, 200.22, 198.65, 200.31. $V_{50_-heart}$=26.07, 27.1, 26.85, 27.17 $V_{30_-heart}$=33.71, 34.37, 34.15, 34.65 Conclusion : In summary, 3D-CRT, Hybrid planning techniques were found to have acceptableCTV coverage in our study. However the Hybrid planning increased radiation dose exposure to normal tissue. If you apply for treatment of inhomogeneity areas like lung, For best results will be achieved.

A Study on the Moisturizing Effect and Preparation of Liquid Crystal Structures Using Sucrose Distearate Emulsifier (슈크로오스디스테아레이트를 사용한 액정구조의 생성과 보습효과에 관한 연구)

  • Kwak, Myeong-Heon;Kim, In-Young;Lee, Hwan-Myung;Park, Joo-Hoon
    • Journal of the Korean Applied Science and Technology
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    • v.33 no.1
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    • pp.1-12
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    • 2016
  • This study is to make the liquid crystalline structure using sucrose distearate (Sucro-DS) emulsifier to create the hydrophilic type oil-in-water (O/W) emulsion, the droplets of the emulsion having a structure of a multi-lamellar structure. We have studied the physicochemical properties of Sucro-DS using those techniques. And it has been studied in the emulsion performance. In order to form the liquid crystalline structure applying 3 wt% of Sucro-DS, 5 wt% of glycerin, 5 wt% of squalane, 5 wt% of capric/caprylic triglyceride, 3wt% of cetostearyl alcohol, 1wt% of glyceryl mono-stearate, 78 wt% of pure water in mixture having the lamellar structure of stable multi-layer system was found to formed. By applying them, they were described how to create an unstable active material encapsulated cream. Further, the moisturizing cream was studied using this technique. It reported the results to the skin improvement effect by the human clinical trials. The pH range to produce a stable liquid crystal phase using a Sucro-DS was maintained in 5.2~7.5. In order to increase the stability of the liquid crystal, it was when behenyl alcohol containing 3 wt%, the hardness at this time was 13 kg/mm,min. Viscosity of the same amount was 25,000mPas/min. After a test for the effects of the emulsions, the concentration of 6 wt% Sucro-DS is that was appropriate, the particle size of the liquid crystal was 4~6mm. It was observed through a microscope analysis, reliability of the liquid crystal changes for 3 months was found to get stable at each $4^{\circ}C$, $25^{\circ}C$ and $45^{\circ}C$. In clinical trial test, before applying a moisturizing effect it was $13.4{\pm}7%$. Moisturizing cream liquid crystal was not formed in $14.5{\pm}5%$. Therefore, applying than ever before could see the moisture about 8.2% was improved. On the other hand, it was the moisturizing effect of the liquid cream is $19.2{\pm}7%$. The results showed that 43.3% improvement than that previously used. Applications fields, Sucro-DS emulsifier used liquid cream, lotion, eye cream and a variety of formulations can be developed, as well as the cosmetics industry is expected to be wide fields in the application of the external preparation for skin emulsion technology in the pharmaceutical industry and pharmaceutical industry.

The role of $Na^+-Ca^{2+}$ exchange on calcium activated chloride current in single isolated cardiac myocyte in pulmonary vein of rabbit.

  • Kim, Won-Tae;Lee, Yoon-Jin;Ha, Jeong-Mi;Han Choe;Jang, Yeon-Jin;Park, Chun-Sik;Lee, Chae-Hun m
    • Proceedings of the Korean Biophysical Society Conference
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    • 2003.06a
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    • pp.37-37
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    • 2003
  • We have shown the $Ca^{2+}$-activated chloride current is present in cardiac myocyte in rabbit pulmonary vein (Kim et al., 2002). This current amplitude was increased as [N $a^{+}$]$_{i}$ was increased and we suggested this chloride current may be involve in the spontaneous action potential frequency change. Since this current is activated by the increase of intracellular $Ca^{2+}$, we would like to test what is the inducer of the increase of [C $a^{2+}$]$_{i}$ between a L-type $Ca^{2+}$-current or a reverse mode of N $a^{+}$-C $a^{2+}$ exchange current. White rabbit (1.5 kg) was used and anesthetized with Ketamin (100 mg/kg). Pulmonary vein (PV) was isolated and sleeve area between left atrium and PV was dissected. Using collagenase (Worthington 0.7 mg/cc), single cardiac myocytes were isolated. In the presence of 15 mM of N $a^{+}$, three steps of voltage pulses were applied (holding potential : -40 ㎷, -80 ㎷ for 50 msec, 30 ㎷ for 5 msec, 10 ㎷ steps from -70 ㎷ to 60 ㎷). The inward and outward tail current was activated after brief 5 msec prepulse. The outward tail current was blocked by the removal of extracellular chloride substituted by glucuronic acid or by a chloride channel blocker, 5 mM 9-AC. But the inward tail current was still remained even though the amplitude was decreased. The reversal potentials were changed to the direction of the change of chloride equilibrium potential ( $E_{Cl}$ ) but the shift of equilibrium potential was not enough to match to the theoretical equilibrium potential shift. In the presence of L-type $Ca^{2+}$ channel blocker, nifedipine 1 uM, inward tail currents were greatly reduced but the outward current tail currents were still remained. In the presence of N $a^{+}$-C $a^{2+}$ exchange current blocker, 10 uM KB-R7943, the inward and outward tail currents were blocked almost completely. We tried to test the $Ca^{2+}$sensitivity of the chloride current with various [C $a^{2+}$]$_{i}$ in pipette solution from 100 nM to 1 uM but we failed to activate $Ca^{2+}$-activated chloride currents even though the cell became contracted in the presence of 1 uM $Ca^{2+}$. From these results, we could conclude that the increase of [C $a^{2+}$]$_{i}$ to activate the outward $Ca^{2+}$-activated chloride current was mainly induced by the activation of the reverse mode of N $a^{+}$-C $a^{2+}$ exchanger, But for the increase of [C $a^{2+}$]$_{i}$ to activate the inward tail current, L-type $Ca^{2+}$ current may be the major provoking current. Since the cytosolic increase of [C $a^{2+}$]$_{i}$ through pipette solution have failed to activate $Ca^{2+}$-activated chloride current, this chloride current may have very low $Ca^{2+}$ sensitivity or a comparmental increase $Ca^{2+}$ such as in subsarcolemmal space may activate the chloride current. Since there are several reports and models that the increase of $Ca^{2+}$ in subsarcolemmal space would be over several to tens of uM, both possibility may be valid together.uM, both possibility may be valid together.

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Study on the Oral Health Care by Parents Who have The Child (자녀(子女)에 대한 구강(口腔) 보건(保健) 기초(基礎) 지식(知識)에 관한 연구(硏究) (대구시내(大邱市內) 치과내원(齒科內院) 환자(患者)의 부모(父母)를 중심(中心)으로))

  • Lee, Jong-Do
    • Journal of Technologic Dentistry
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    • v.19 no.1
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    • pp.175-184
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    • 1997
  • The purpose of this study is to examine the effect of parents knowledge on oral health status toward their children. This study was carried out to investigate and analyze the congnitive degree of dental subjects and public who have an experience to be treated for their teeth on the dental knowledge, operative dentistry, and dental prothesis in the oral health care through the questionnaires. The results are as follows; 1. In questioning the fundamental knowledges, 47.6% of respondents in their thirties said that milk tooth of their children are number 20. Although schooling level of their parents is not rel evant to this survey, 21.9% who have only high-school diploma, said also "number 20". As a conclusion, most parents have a big concern in their children's teeth. 2. 44.0% parents answered, asked "who do decayed teeth sping up, and 26.4% said" It is why children eat sugary. Asked "What is efficient preventive measures decayed teeth", 26.5% said it is very relevant to be in the utilization of F-tooth-paste. 3. For children's good theeth, periodically brushing is the important. Most parents recognized brushing efficient. 4. In questioning the possession amount of decayed teeth, 45.8% have more than four. Usually those parents who have children filled their decayed teeth with artificial or installed with dental prosthesis. As a conclusion age is relevant in this study in P<0.05 level. 5. In asking for efficient starting-year of tooth brushing, 42.6% said that 2 or 3 year age is the most efficient, and especially 80.6% teath children to learn brushing themselves(P<0.05) 6. In surveying the way they obtained dental information, 38.9% were given from mass media, but 90% were once not delivered with the education of dental health. Because parents have been know narrow and deficient information of dental health mass media, experts in dental health have to deliver help their parents to be delivered with systematical dental information. The conclustion of this study can summarized that parent's role very important to their children's tooth health and the education program for systematical dental information should be delivered to their parents.

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Electrolytic Reduction of 1 kg-UO2 in Li2O-LiCl Molten Salt using Porous Anode Shroud (Li2O-LiCl 용융염에서의 다공성 양극 슈라우드를 이용한1kg 우라늄산화물의 전해환원)

  • Choi, Eun-Young;Lee, Jeong;Jeon, Min Ku;Lee, Sang-Kwon;Kim, Sung-Wook;Jeon, Sang-Chae;Lee, Ju Ho;Hur, Jin-Mok
    • Journal of the Korean Electrochemical Society
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    • v.18 no.3
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    • pp.121-129
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    • 2015
  • The platinum anode for the electrolytic reduction process is generally surrounded by a nonporous ceramic shroud with an open bottom to offer a path for $O_2$ gas produced on the anode surface and prevent the corrosion of the electrolytic reducer. However, the $O^{2-}$ ions generated from the cathode are transported only in a limited fashion through the open bottom of the anode shroud because the nonporous shroud hinders the transport of the $O^{2-}$ ions to the anode surface, which leads to a decrease in the current density and an increase in the operation time of the process. In the present study, we demonstrate the electrolytic reduction of 1 kg-uranium oxide ($UO_2$) using the porous shroud to investigate its long-term stability. The $UO_2$ with the size of 1~4mm and the density of $10.30{\sim}10.41g/cm^3$ was used for the cathode. The platinum and 5-layer STS mesh were used for the anode and its shroud, respectively. After the termination of the electrolytic reduction run in 1.5 wt.% $Li_2O-LiCl$ molten salt, it was revealed that the U metal was successfully converted from the $UO_2$ and the anode and its shroud were used without any significant damage.

Fabrication and Performance of Anode-Supported Flat Tubular Solid Oxide Fuel Cell Unit Bundle (연료극 지지체식 평관형 고체산화물 연료전지 단위 번들의 제조 및 성능)

  • Lim, Tak-Hyoung;Kim, Gwan-Yeong;Park, Jae-Layng;Lee, Seung-Bok;Shin, Dong-Ryul;Song, Rak-Hyun
    • Journal of the Korean Electrochemical Society
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    • v.10 no.4
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    • pp.283-287
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    • 2007
  • KIER has been developing the anode-supported flat tubular solid oxide fuel cell unit bundle for the intermediate temperature($700{\sim}800^{\circ}C$) operation. Anode-supported flat tubular cells have Ni/YSZ cermet anode support, 8 moi.% $Y_2O_3$ stabilized $ZrO_2(YSZ)$ thin electrolyte, and cathode multi-layer composed of Sr-doped $LaSrMnO_3(LSM)$, LSM-YSZ composite, and $LaSrCoFeO_3(LSCF)$. The prepared anode-supported flat tubular cell was joined with ferritic stainless steel cap by induction brazing process. Current collection for the cathode was achieved by winding Ag wire and $La_{0.6}Sr_{0.4}CoO_3(LSCo)$ paste, while current collection for the anode was achieved by using Ni wire and felt. For making stack, the prepared anode-supported flat tubular cells with effective electrode area of $90\;cm^2$ connected in series with 12 unit bundles, in which unit bundle consists of two cells connected in parallel. The performance of unit bundle in 3% humidified $H_2$ and air at $800^{\circ}C$ shows maximum power density of $0.39\;W/cm^2$ (@ 0.7V). Through these experiments, we obtained basic technology of the anode-supported flat tubular cell and established the proprietary concept of the anode-supported flat tubular cell unit bundle.

The Significance of the " GukMinSoHakDokBon", published in 1895, on the History of Science Education (1895년에 발간된 "국민소학독본"의 과학교육사적 의의)

  • Park, Jongseok;Kim, SooJung
    • Journal of The Korean Association For Science Education
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    • v.33 no.2
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    • pp.478-485
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    • 2013
  • "GukMinSoHakDokBon", published in 1895, is the first national textbook designated by the Education Institute. Ten of the 41 chapters consist of scientific contents. In this thesis, some the contents are reviewed in detail and studied to see what significance it has in view of science education. The scientific contents described in "GukMinSoHakDokBon" include Plants Change, Clock, Camels, Wind, Hive, Respiration, Crocodiles, Nature of Animals, and Chemical Elements. For that kind of diversity, it was told that "GukMinSoHakDokBon" was not considered for normal students, and there were many ambiguities due to in sufficient explanations. Some of the contents were even technically wrong. So it has been noted that the scientific contents of "GukMinSoHakDokBon" have more significance in providing new information at that time but not in understanding newly-organized scientific knowledge. However, it is obvious that the early science education in Korea is composed of the methods of reading "GukMinSoHakDokBon". This is a common figure, which can be found in "Willson's Reader", the elementary reading textbook in the U.S. in the 1860's or "小學讀本" by the Ministry of Education in Japan. One thing remarkable is "GukMinSoHakDokBon" induced students' interests through the use of storytelling method for introducing some unfamiliar scientific knowledge. There is no doubt that "GukMinSoHakDokBon" has a very positive role in increasing students interest and intelligence. These advantages are being actively applied in the present model of storytelling education these days. Therefore, "GukMinSoHakDokBon" can be regarded as both a language textbook and an early figure in science education, and it can be also considered that "GukMinSoHakDokBon" has a significance not only in approaching scientific substances theoretically but in using storytelling methods to deliver unfamiliar and strange knowledges to students.

International Liability for Damage Caused by Space Debris (우주잔해 손해에 대한 국제책임)

  • Kim, Dong-Uk
    • The Korean Journal of Air & Space Law and Policy
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    • v.23 no.2
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    • pp.173-205
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    • 2008
  • Space debris have frequently caused damage to space objects like satellites in orbits and sometimes have fallen on the earth. Such increase in space debris will lead to the high possibility of threatening space activities of mankind. However, it is not so easy for the damage caused both by identified and by unidentified space debris to be recovered since in the regime of the current international law, there is no legislation of prescribing the damage done by space debris. For overcoming the limitation it seems desirable that either the Liability Convention should partly be amended or new international law regime should be established. For instance, 'space debris' should be included in the new definition of 'space object' and the range of launching should also be defined clearly by making the concept of 'launching' somewhat more specified. Moreover, the subject of international liability for damage caused by space debris should be divided into two classes: the subject before and after registration. While in case of before-registration launch states should be held liable for any damage jointly or individually, in case of after-registration 'the state of registry' or 'owner' of the space debris should be. In the event of damage being caused elsewhere than on the surface of the earth to a space object of other State, 'fault-based liability' is currently applied. But it needs to be changed into 'absolutely liability'. In this paper, 'Liability Pool', 'Insurance', 'Market-Share Liability' are presented as aid devices of the damages resulting from unidentified space debris. They should be defined through the amendment of the Liability Convention or another international treaty. Some day there comes a time when our country shall possess many of the astronomical price of satellites. It means that we can't be free from the damage by the increasing number of space debris. Provided that our satellites are damaged by such space debris, it will do the satellites damage and cause impaired functioning or troubles in operation. As a result, if we are not paid for the damage by space debris, we will be confronted with tremendous economic loss because it is necessarily connected with the excess burden of taxation. Thus, an international agreement regarding the measures of the compensation for space debris damage must be made very soon.

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A Study on the Effects of the Antipoverty Policy in Local Community : Focusing on the Self-Support System In Korea (지역사회 탈빈곤 정책의 효과 분석 : 경남, 전북지역 자활후견기관 운영의 성과 및 한계 분석과 개선방안의 모색)

  • Lee, Sang-Rok;Jin, Jae-Moon
    • Korean Journal of Social Welfare
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    • v.52
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    • pp.241-272
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    • 2003
  • The Self-Support Program was introduced as an antipoverty policy at 2002 year in Korea. But, the Self-Support Program's negative or positive effects have been debated from diverse perspectives to the present. Thus, in this paper, we analyzed the effects of the Self-Support Program using the survey data from program participants. Even though the effects of Workfare Programs can be evaluated by various indicators(ex. income, employment status, poverty status, etc.), in our analysis the effects of the Self-Support Program are evaluated by participants' self-reliant attitudes and behaviors. Major findings are as follows. First, we found that some kinds of self-reliant attitudes(ex. work commitment, self-esteem, etc.) were build up through participation on the Self-Support program, but some kinds of self-reliant factors(job competence and skill, self-sufficiency prospect, etc.) which are more relevant to the self-sufficiency were not build up thorough it. Second, we found the positive effects of the program among people who are females, olders, less educated, more healthy, and the participants who have acquired more certificate of qualifications. Third, we also found that self-support center's job training program, adequate task matching, agency climates and intra-networks influence on the positive effects of the Self-Support Program. These findings suggest that the Self-Support Program has not been successful up to now and it's reformations are required. It means that objectives of the Self-Support Program as an anti-poverty policy must be obvious and program contents must be diverse. And also program administration systems need to be reformed in oder to raise the effectiveness of the Self-Support Program.

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Middle School Home Economics Teachers Perspective about Home Economics Curriculum and Housing Education Value (중학교 가정과 교사의 교육과정 관점과 주거교육 가치관)

  • Lee, Yeon-Jung;Cho, Jae-Soon;Chae, Jung-Hyun
    • Journal of Korean Home Economics Education Association
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    • v.19 no.4
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    • pp.219-232
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    • 2007
  • The purpose of this study was to investigate middle school Home Economics(HE) teachers' perspective on HE curriculum, their Housing Education Value in Home Economics, and then find out correlations between them. Questionnaire was administered to HE teachers who had experienced teaching Housing content over the whole country through e-mail or face-to-face meeting. 207 data collected from the responses were finally analyzed statistically with mean, standard deviation, percentage, T-test, one-way ANOVA, post verification(Scheffe) and Pearson correlation by using SPSS/WIN(ver. 10.0) program. The results of the study were as follows: First, about Home Economics teachers' perspective on HE curriculum, the existential perspective was the highest, followed by the structural perspective and the traditional perspective. Second, about their perspectives on Housing Education Value, generally the most important thing they value was an aspect of ecology, followed by an aspect of economics, an aspect of Socio-Psychology, an aspect of space planning, an aspect of local environment, an aspect of career education, an aspect of culture, an aspect of housing management and an aspect of housing policy. Third, about the relation between their perspectives on curriculum and Housing Education Value, among 9 kinds of Housing Education Value, the traditional perspective was low associated with only housing management value including to Housing Education Value. However, the existential perspective and the structural perspective tended to be moderately or low associated with most of the values including to Housing Education Value.

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