• Title/Summary/Keyword: threshold effect

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Therapeutic Effects of Korean Medical Treatment Combined with Threshold Sound Conditioning on Bilateral Sudden Sensorineural Hearing Loss : A Case Report (한방 복합 치료 및 소리재활치료로 호전된 양측성 돌발성 난청 치험 1례)

  • Park, Soyoung;Jea, Ha-Kyung;Min, Ye-Eun;Kang, Jun-Hyeok;Hong, Eun-Been
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.35 no.2
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    • pp.72-81
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    • 2022
  • Objectives : The purpose of this study is to report the case of a bilateral sudden sensorineural hearing loss patient whose hearing had improved by Korean medical treatment combined with threshold sound. Methods : A woman diagnosed with bilateral sudden sensorineural hearing loss has treated with Korean medical interventions(acupuncture combined with electromagnetic stimulation and pharmacoacupuncture) and threshold sound conditioning(TSC) for 20 weeks. Pure tone audiometry(PTA) was performed for the evaluation. Results : The average hearing level has improved from mild to normal level. The level of tinnitus has decreased from VAS 10 to VAS 4. Conclusions : We observed an improvement in a bilateral sudden sensorineural hearing loss patient's hearing and hereby suggest the possibility of Korean medical treatment and TSC's ameliorating effect on sensorineural hearing loss.

Hybrid Corrosion Inhibitor-Based Zwitterions and Phosphate in Reinforced Concrete: Determining Chloride Threshold and Service Life (철근 콘크리트의 Zwitterion 및 인산염 기반 하이브리드 부식 억제제: 염화물 임계값 및 사용 수명 결정)

  • Tran, Duc Thanh;Jeong, Min-Goo;Lee, Han-Seung;Yang, Hyun-Min;Singh, Jitendra Kumar
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2023.05a
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    • pp.33-34
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    • 2023
  • Corrosion of reinforcement steel is a major cause of deterioration in reinforced concrete (RC) structures. In order to protect these structures from corrosion, corrosion inhibitors are added to the concrete mix. In recent years, zwitterionic compounds have shown promising results as corrosion inhibitors in concrete due to their ability to form a protective layer on the surface of the reinforcement steel. The experimental study involves preparing concrete samples with different concentrations of adding the hybrid corrosion inhibitor at a high concentration of chloride ions. This study aims to determine the chloride threshold value and service life of hybrid corrosion inhibitors in reinforced concrete based on zwitterions. The samples are subjected to accelerated corrosion tests in a chloride environment to determine the threshold value and service life of the corrosion inhibitor. The effect of hybrid inhibitor on mechanical properties is guaranteed in allowable range. The chloride threshold concentration and service life of hybrid inhibitor containing samples perform greater than those of plain RC.

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Antinociceptive Effect of Memantine and Morphine on Vincristine-induced Peripheral Neuropathy in Rats

  • Park, Byoung-Yoon;Park, Sang-Hee;Kim, Woong-Mo;Yoon, Myung-Ha;Lee, Hyung-Gon
    • The Korean Journal of Pain
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    • v.23 no.3
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    • pp.179-185
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    • 2010
  • Background: Vincristine-induced peripheral neuropathy is a major dose limiting side effect and thus effective therapeutic strategy is required. In this study, we investigated the antinociceptive effect of memantine and morphine on a vincristine-induced peripheral neuropathy model in rats. Methods: Male Sprague-Dawley rats weighing 220-240 g were used in all experiments. Rats subsequently received daily intraperitoneal injections of either vincristine sulfate (0.1 ml/kg/day) or saline (0.1 ml/kg/day) over 12 days, immediately following behavioral testing. For assessment of mechanical allodynia, mechanical stimuli using von Frey filament was applied to the paw to measure withdrawal threshold. The effects of N-methyl-D-aspartate receptors antagonist (memantine; 2.5, 5, 10 mg/kg intraperitoneal), opioid agonist (morphine; 2.5, 5, 10 mg/kg intraperitoneal) and vehicle (saline) on vicristine-induced neuropathy were evaluated. Results: Mechanical allodynia developed over the course of ten daily injections of vincristine relative to groups receiving saline at the same time. Morphine abolished the reduction in paw withdrawal threshold compared to vehicle and produced dose-responsiveness. Only the highest dose of memantine (10 mg/kg) was able to increase paw withdrawal threshold compared to vehicle. Conclusions: Systemic morphine and memantine have an antinociceptive effect on the vincristine-induced peripheral neuropathy model in rats. These results suggest morphine and memantine may be an alternative approach for the treatment of vincristine-induced peripheral neuropathic pain.

Single Crystal Silicon Thin Film Transistor using 501 Wafer for the Switching Device of Top Emission Type AMOLEDs (SOI 웨이퍼를 이용한 Top emission 방식 AMOLEDs의 스위칭 소자용 단결정 실리콘 트랜지스터)

  • Chang, Jae-Won;Kim, Hoon;Shin, Kyeong-Sik;Kim, Jai-Kyeong;Ju, Byeong-Kwon
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.16 no.4
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    • pp.292-297
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    • 2003
  • We fabricated a single crystal silicon thin film transistor for active matrix organic light emitting displays(AMOLEDs) using silicon on insulator wafer (SOI wafer). Poly crystal silicon thin film transistor(poly-Si TFT) Is actively researched and developed nowsdays for a pixel switching devices of AMOLEDs. However, poly-Si TFT has some disadvantages such as high off-state leakage currents and low field-effect mobility due to a trap of grain boundary in active channel. While single crystal silicon TFT has many advantages such as high field effect mobility, low off-state leakage currents, low power consumption because of the low threshold voltage and simultaneous integration of driving ICs on a substrate. In our experiment, we compared the property of poly-Si TFT with that of SOI TFT. Poly-Si TFT exhibited a field effect mobility of 34 $\textrm{cm}^2$/Vs, an off-state leakage current of about l${\times}$10$\^$-9/ A at the gate voltage of 10 V, a subthreshold slope of 0.5 V/dec and on/off ratio of 10$\^$-4/, a threshold voltage of 7.8 V. Otherwise, single crystal silicon TFT on SOI wafer exhibited a field effect mobility of 750 $\textrm{cm}^2$/Vs, an off-state leakage current of about 1${\times}$10$\^$-10/ A at the gate voltage of 10 V, a subthreshold slope of 0.59 V/dec and on/off ratio of 10$\^$7/, a threshold voltage of 6.75 V. So, we observed that the properties of single crystal silicon TFT using SOI wafer are better than those of Poly Si TFT. For the pixel driver in AMOLEDs, the best suitable pixel driver is single crystal silicon TFT using SOI wafer.

Effect of Cupping Therapy on Range of Motion, Pain Threshold, and Muscle Activity of the Hamstring Muscle Compared to Passive Stretching

  • Kim, Jae-Eun;Cho, Ji-Eun;Do, Kwang-Sun;Lim, Seung-Yeop;Kim, Hee-Joong;Yim, Jong-Eun
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.3
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    • pp.23-32
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    • 2017
  • PURPOSE: Flexibility and range of motion are very important factors in sports performance, rehabilitation, and musculoskeletal pain. The purpose of this study was to measure the effects of cupping therapy on flexibility, muscle activity, and pain threshold of hamstring muscle compared to passive stretching in healthy subjects. METHODS: Thirty healthy subjects were randomly assigned in a crossover design to cupping therapy and passive stretching. Subjects were tested to compare their effects according to the intervention such as Passive range of motion (PROM) (straight leg raising) and active range of motion (AROM). And algometer (pain) testing and MVC assessment using EMG were performed as dependent variables. RESULTS: The cupping therapy group and passive stretching group showed significant differences in all variables including PROM (p=.00, p=.00), AROM (p=.00, p=.03), Pain Threshold (p=.03, p=.08), Semitendinosus MVC (p=.01, p=.00), and Biceps femoris MVC (p=.01, p=.16). There were no significant differences between the two groups in all variables. CONCLUSION: These findings of this study suggested that cupping therapy has as much positive effect on flexibility, pain threshold, and muscle contraction as passive stretching. Also, it is more convenient and easier to work on patients than passive stretching. Therefore, cupping therapy should be considered as another option to treat range of motion, pain, and muscle activity in the clinical field.

A Comparison of The Effect of Stretching Technique on Hamstring Muscle for Flexibility, Strength, Pressure Pain Threshold Value and Muscle Tone (스트레칭 기법에 따른 뒤넙다리근의 유연성, 근력, 압통 역치, 근 긴장도에 미치는 효과 비교)

  • Park, Hoon-Young;Lee, Myung-Mo
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.4
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    • pp.39-46
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    • 2017
  • PURPOSE: The effectiveness of the stretching to increase the range of motion of the joint, reduce the risk of injury, enhance athletic performance or decrease post exercise muscle soreness. This study was to compare the effect of the stretching method applied on the shortened hamstring muscle for flexibility, strength, pressure pain threshold value and muscle tone. METHODS: This study is a two-group pretest- posttest design. Fifty-four healthy young adults were randomly assigned to a vibration-assisted stretching group (VASG, n=27) or a static stretching group (SSG, n=27). Participants performed each stretch in 4 sets of 30 seconds each. A 30-second break time was provided between the sets. The range of motion, strength, pressure pain threshold values and muscle tone of the hamstring muscle were measured to compare the effects of the stretching methods. RESULTS: Both the VASG and the SSG participants showed significant improvement in the range of motion and strength (p<.05); however, the increase in the VASG was significantly higher than that in the SSG (p<.05). The pressure pain threshold values and muscle tone were significantly decreased only in the VASG (p<.05). CONCLUSION: These findings indicate that vibration-supported stretching is an effective intervention for people with hamstring shortening, with high pain level and muscle tone decrease.

A study on Improvement of sub 0.1$\mu\textrm{m}$VLSI CMOS device Ultra Thin Gate Oxide Quality Using Novel STI Structure (STI를 이용한 서브 0.1$\mu\textrm{m}$VLSI CMOS 소자에서의 초박막게이트산화막의 박막개선에 관한 연구)

  • 엄금용;오환술
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.13 no.9
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    • pp.729-734
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    • 2000
  • Recently, Very Large Scale Integrated (VLSI) circuit & deep-submicron bulk Complementary Metal Oxide Semiconductor(CMOS) devices require gate electrode materials such as metal-silicide, Titanium-silicide for gate oxides. Many previous authors have researched the improvement sub-micron gate oxide quality. However, few have reported on the electrical quality and reliability on the ultra thin gate oxide. In this paper, at first, I recommand a novel shallow trench isolation structure to suppress the corner metal-oxide semiconductor field-effect transistor(MOSFET) inherent to shallow trench isolation for sub 0.1${\mu}{\textrm}{m}$ gate oxide. Different from using normal LOCOS technology deep-submicron CMOS devices using novel Shallow Trench Isolation(STI) technology have a unique"inverse narrow-channel effects"-when the channel width of the devices is scaled down, their threshold voltage is shrunk instead of increased as for the contribution of the channel edge current to the total channel current as the channel width is reduced. Secondly, Titanium silicide process clarified that fluorine contamination caused by the gate sidewall etching inhibits the silicidation reaction and accelerates agglomeration. To overcome these problems, a novel Two-step Deposited silicide(TDS) process has been developed. The key point of this process is the deposition and subsequent removal of titanium before silicidation. Based on the research, It is found that novel STI structure by the SEM, in addition to thermally stable silicide process was achieved. We also obtained the decrease threshold voltage value of the channel edge. resulting in the better improvement of the narrow channel effect. low sheet resistance and stress, and high threshold voltage. Besides, sheet resistance and stress value, rms(root mean square) by AFM were observed. On the electrical characteristics, low leakage current and trap density at the Si/SiO$_2$were confirmed by the high threshold voltage sub 0.1${\mu}{\textrm}{m}$ gate oxide.

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An Organic Electrophosphorescent Device Driven by All-Organic Thin-Film Transistor using Polymeric Gate Insulator

  • Pyo, S.W.;Shim, J.H.;Kim, Y.K.
    • Journal of Information Display
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    • v.4 no.2
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    • pp.1-6
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    • 2003
  • In this paper, we demonstrate that the organic electrophosphorescent device is driven by the organic thin film transistor with spin-coated photoacryl gate insulator. It was found that electrical output characteristics in our organic thin film transistors using the staggered-inverted top-contact structure showed the non-saturated slope in the saturation region and the sub-threshold nonlinearity in the triode region, where we obtained the maximum power luminance that was about 90 $cd/m^2$. Field effect mobility, threshold voltage, and on-off current ratio in 0.45 ${\mu}m$ thick gate dielectric layer were 0.17 $cm^2/Vs$, -7 V, and $10^6$ , respectively. In order to form polyimide as a gate insulator, vapor deposition polymerization process was also introduced instead of spin-coating process, where polyimide film was co-deposited by high-vacuum thermal evaporation from 4,4'-oxydiphthalic anhydride (ODPA) and 4,4'-oxydianiline (ODA) and cured at 150${\sqsubset}$for 1hr. It was also found that field effect mobility, threshold voltage, on-off current ratio, and sub-threshold slope with 0.45 ${\mu}m$ thick gate dielectric films were 0.134 $cm^2/Vs$, -7 V, and $10^6$ A/A, and 1 V/decade, respectively.

Effect of Therapeutic Feedback on Non-Face to Face Exercise for Forward Head Posture: Posture, Muscle Strength, Pressure pain Threshold

  • Kim, Yeri;Kim, Gayoung;Kim, Daye;Shin, Hyeri;Oh, Seonghoon;Yu, Pyeonghwa;Jung, Kyusang;Shin, Wonseob
    • Physical Therapy Rehabilitation Science
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    • v.10 no.2
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    • pp.147-155
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    • 2021
  • Objective: This study is to investigate the effect of real-time feedback from the therapist on posture, muscle strength, pain of subjects with forward head posture based on a non-face-to-face complex exercise program. Design: Two-group pretest-posttest design. Methods: Thirty healthy men and women in their twenties with forward head posture with a Craniovertebral angle of 52° or less were targeted, the final selection was made as 15 experimental groups who performed the non-face-to-face intervention program while receiving real-time feedback and 15 control subjects who performed the non-face-to-face intervention program without providing feedback. Six of them were eliminated, and a total of 24 were conducted as subjects. All exercise groups performed an exercise program three times a week, 30 minutes each, for a total of two weeks. Before and after exercise, Craniovertebral angle (CVA), CranioRotation angle (CRA), muscle strength, and tenderness threshold were evaluated. Results: Significant differences were shown in both groups in CVA, and tenderness threshold before and after exercise (p<0.05), and CRA, the left middle trapezius muscle strength, only in the experimental group (p<0.05). In the comparison of theamount of change between exercise groups, the group that received feedback on CVA, CRA and tenderness threshold showed a significant change than the group without feedback (p<0.05). Conclusions: As a result of this study, it can be seen that the therapist's real-time feedback is more effective in improving the forward head posture. This requires feedback from the therapist on posture correction during non-face-to-face exercise intervention.

Analysis of Short-Channel Effect due to the 2D QM effect in the poly gate of Double-Gate MOSFETs (폴리게이트의 양자 효과에 따른 Double-Gate MOSFET의 단채널 효과 분석)

  • 박지선;신형순
    • Proceedings of the IEEK Conference
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    • 2003.07b
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    • pp.691-694
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    • 2003
  • Density gradient method is used to analyze the quantum effect in MOSFET, Quantization effect in the poly gate leads to a negative threshold voltage shift, which is opposed to the positive shift caused by quantization effect in the channel. Quantization effects in the poly gate are investigated using the density gradient method, and the impact on the short channel effect of double gate device is more significant.

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