• Biomaterials and Biomechanics in Bioengineering
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• 제2권2호
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• pp.61-69
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• 2015

Undifferentiated stem cells are being studied to obtain information on the therapeutic potential of isolates that are produced. Dental Pulp Stem Ccell (DPSC) may provide an abundant supply of highly proliferative, multipotent Mesenchymal Stem Cells (MSC), which are now known to be capable of regenerating a variety of human tissues including bone and other dental structures. Many factors influence DPSC quality and quantity, including the specific methods used to isolate, collect, concentrate, and store these isolates once they are removed. Ancillary factors, such as the choice of media, the selection of early versus late passage cells, and cryopreservation techniques may also influence the differentiation potential and proliferative capacity of DPSC isolates. This literature review concludes that due to the delicate nature of DPSC, more research is needed for dental researchers and clinicians to more fully explore the feasibility and potential for isolating and culturing DPSCs extracted from adult human teeth in order to provide more accurate and informed advice for this newly developing field of regenerative medicine.

• Clinical Endoscopy
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• 제56권6호
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• pp.693-705
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• 2023

Upper gastrointestinal postsurgical leaks are life-threatening conditions with high mortality rates and are one of the most feared complications of surgery. Leaks are challenging to manage and often require radiological, endoscopic, or surgical intervention. Steady advancements in interventional endoscopy in recent decades have allowed the development of new endoscopic devices and techniques that provide a more effective and minimally invasive therapeutic option compared to surgery. Since there is no consensus regarding the most appropriate therapeutic approach for managing postsurgical leaks, this review aimed to summarize the best available current data. Our discussion specifically focuses on leak diagnosis, treatment aims, comparative endoscopic technique outcomes, and combined multimodality approach efficacy.

• 대한영상의학회지
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• 제84권2호
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• pp.483-488
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• 2023

경추 수술 중 발생한 척추 동맥 손상은 드물지만 중요하다. 중재적 혈관내 치료 기술의 발전으로 척추 동맥 손상에 대한 치료 접근 방식이 바뀌었지만 확립된 치료 방침은 아직 없다. 우리는 트리플 스텐트 시술 실패 후 플러그 앤 패치 방식으로 혈관내 코일 시술을 하여 척추 동맥 손상으로 인한 가동맥류를 성공적으로 치료한 사례를 보고하고자 한다.

• Journal of Radiation Protection and Research
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• 제28권3호
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• pp.225-231
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• 2003

Up-front irradiation technique as 3-dimensional conformation, or intensity modulation has kept large proportion of brain tumors from being complicated with acute radiation reactions in the normal tissue during or shortly after radiotherapy. For years, we've cannot help but counting on 2-D vertex beam technique to reduce acute reactions in the brain tumor patients because we're not equipped with 3-dimensional planning system. We analyzed its advantages and limitations in the clinical application. From 1998 to 2001, vertex or oblique vertex beams were applied to 35 patients with primary brain tumor and 25 among them were eligible for this analysis. Vertex(V) plans were optimized on the reconstructed coronal planes. As the control, we took the bilateral opposed techniques(BL) otherwise being applied. We compared the volumes included in 105% to 50% isodose lines of each plan. We also measured the radiation dose at various extracranial sites with TLD. With vertex techniques, we reduced the irradiated volumes of contralateral hemisphere and prevented middle ear effusion at contralateral side. But the low dose volume increased outside 100%; the ratio of V to BL in irradiated volume included in 100%, 80%, 50% was 0.55+/-0.10, 0.61+/-0.10, and 1.22+/-0.21, respectively. The hot area within 100% isodose line almost disappeared with vertex plan; the ratio of V to BL in irradiated volume included in 103%, 105%, 108% was 0.14+/-0.14, 0.05./-0.17, 0.00, respectively. The dose distribution within 100% isodose line became more homogeneous; the ratio of volume included in 103% and 105% to 100% was 0.62+/-0.14 and 0.26+/-0.16 in BL whereas was 0.16+/-0.16 and 0.02+/-0.04 in V. With the vertex techniques, extracranial dose increased up to $1{\sim}3%$ of maximum dose in the head and neck region except submandibular area where dose ranged 1 to 21%. From this data, vertex beam technique was quite effective in reduction of unnecessary irradiation to the contralateral hemispheres, integral dose, obtaining dose homogeneity in the clinical target. But it was associated with volume increment of low dose area in the brain and irradiation toward the head and neck region otherwise being not irradiated at all. Thus, this 2-D vertex technique can be a useful quasi-conformal method before getting 3-D apparatus.

• The Korean Journal of Pain
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• 제31권1호
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• pp.27-38
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• 2018

Background: Related to escalating health care costs and the questionable effectiveness of multiple interventions including lumbar facet joint interventions, cost effectiveness or cost utility analysis has become the cornerstone of evidence-based medicine influencing coverage decisions. Methods: Cost utility of therapeutic lumbar facet joint nerve blocks in managing chronic low back pain was performed utilizing data from a randomized, double-blind, controlled trial with a 2-year follow-up, with direct payment data from 2016. Based on the data from surgical interventions, utilizing the lowest proportion of direct procedural costs of 60%, total cost utility per quality adjusted life year (QALY) was determined by multiplying the derived direct cost at 1.67. Results: Patients in this trial on average received $5.6{\pm}2.6$ procedures over a period of 2 years, with average relief over a period of 2 years of $82.8{\pm}29.6$ weeks with $19{\pm}18.77$ weeks of improvement per procedure. Procedural cost for one-year improvement in quality of life showed USD $2,654.08. Estimated total costs, including indirect costs and drugs with multiplication of direct costs at 1.67, showed a cost of USD $4,432 per QALY. Conclusions: The analysis of therapeutic lumbar facet joint nerve blocks in the treatment of chronic low back pain shows clinical effectiveness and cost utility at USD $2,654.08 for the direct costs of the procedures, and USD $4,432 for the estimated overall cost per one year of QALY, in chronic persistent low back pain non-responsive to conservative management.

• 한국임상수의학회지
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• 제31권5호
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• pp.461-465
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• 2014

더러브렛종 세 살짜리 경주용 수말이 평보 및 속보 걸음에서 좌측 앞다리의 뚜렷한 파행, 경미한 열감 및 통증을 발현하여 한국마사회 동물병원에 내원하였다. 왼쪽 발굽의 내외측의 길이 차이가 매우 큰, 전형적인 부등 제종에 기인한 제측 열제로 진단되었다. 열제면 고정, 부중 감소용 편자 장착 및 인공제벽 도포 등 다양한 처치방법을 약 2개월 간격으로 총 5차례 선택적으로 적용하여 좋은 결과를 나타내었으며, 발굽에 열감과 파행이 완전히 사라진 바 치료 개시 약 36주차 후부터 출전을 위한 훈련을 개시하였다. 특히 섬유강화플라스틱(FRP)재질의 연결판과 치료용 편자 장착 등 장제요법은 부등제종에 기인한 제측 열제의 치료에 있어서 매우 도움이 되는 것으로 판단되었다.

• 대한심미치과학회지
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• 제7권1호
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• pp.32-40
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• 1998

Alveolar ridge augmentation and preservation techniques designed to reconstruct deformed alveolar ridge now occupy a major role in esthetic dentistry. Previously, deformed alveolar ridges were filled with plastic materials(porcelain or resin) of prosthesis to restore ridge contours, which resulted in larger teeth and food impaction under the pontic base. So, prostheses of this type were unacceptable and really detectable when patients smiled. But nowadays, alveolar ridge augmentation procedures enable the dentists to provide patients with fixed prostheses that are esthetic. The development of guided tissue regeneration technique and materials also have made a major impact on extending the scope of therapeutic horizons in dentistry.

• Journal of Yeungnam Medical Science
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• 제25권2호
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• pp.85-91
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• 2008

Intensity-modulated radiation therapy (IMRT) is believed to be one of the best radiation treatment techniques. IMRT is able to deliver fatal doses of radiation to the tumor region with minimal exposure of critical organs. It is essential to have a comprehensive quality assurance program to assure precision and accuracy in treatment, due to the character of IMRT. We applied quality assurance technique to the Eclipse treatment planning system and sought to determine its effectiveness in patient treatment planning. An acrylic phantom, film, and an ionization chamber were used in this study.

• 대한치과의사협회지
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• 제51권7호
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• pp.389-397
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• 2013

Sedation is frequently required to relieve anxiety in the field of dentistry. Among sedation techniques, oral sedation has been widely used because it is easy for administration and has a wide acceptability for dentists. This article discuss the pharmacology of oral sedatives and therapeutic considerations of these drugs, and finally how to manage apprehensive patients using oral sedation. Also, we recommend how pertinent drugs should be used to maintain an adequate level of sedation, not deep sedation

• 대한불안의학회지
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• 제12권1호
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• pp.42-46
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• 2016

The therapeutic effect of cognitive behavioral therapy (CBT) for patients with Social Anxiety Disorder (SAD) is supported by evidence from numerous studies. This article provides an overview of cognitive models and major techniques (i.e., cognitive restructuring and exposure) of CBT for SAD, developed by the study group of SAD in the Korean Academy of Anxiety Disorder. Korean-culture specific factors and new trends such as a third wave of CBT are also described.