• Title/Summary/Keyword: theory of evidence

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Yangkyuksanhwa-Tang Attenuates Ischemic Brain Injury in a Focal Photothrombosis Stroke Model (뇌허혈 마우스모델에서 양격산화탕이 뇌 손상 완화에 미치는 효과)

  • Han, Do-Kyung;Pak, Malk-Eun;Kwon, Ok-Sun;Choi, Byung-Tae
    • Journal of Life Science
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    • v.29 no.11
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    • pp.1258-1266
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    • 2019
  • Yangkyuksanhwa-Tang (YKSH), consisting of nine different herbs, is commonly used in Soyangin-type individuals with stroke, based on the Sasang Constitution Theory in Korea. However, no evidence has yet confirmed a beneficial effect of YKSH in ischemic stroke treatment. In this study, we investigated the effects of YKSH on ischemic brain injury in a mouse model of cerebral ischemia. Focal cerebral ischemia in mice was induced by photothrombosis, and behavioral recovery was evaluated. Infarct volume, inflammation, and newly generated cells were evaluated by histology and immunochemistry. YKSH treatment resulted in a significant recovery from the motor impairments induced by focal cerebral ischemia, as determined with wire grip and rotarod tests. YKSH treatment also decreased the infarct volume and the number of cells positive for tumor necrosis factor-${\alpha}$ and myeloperoxidase when compared with a vehicle-treated control group. By contrast, YKSH treatment considerably increased the number of cells positive for glial fibrillary acidic protein and ionized calcium-binding adapter molecule 1, as well as the number of cells doubly positive for Ki67/doublecortin when compared with the vehicle-treated group. These results suggest that YKSH treatment attenuated the infarct size by anti-inflammatory action, astrocyte and microglia activation, and neuronal proliferation, thereby facilitating neurofunctional recovery from a cerebral ischemic assault. YKSH could therefore be a potential treatment for neurofunctional restoration of the injured brains of patients with stroke.

Effect of Extracts for Herbal Medicines on the Inhibition of Whole Blood Aggregation (한약재 추출물에 대한 전혈응집억제 효능 검색)

  • Jeon, Won-Kyung;Yoo, Bo-Kyung;Kim, Yeong-Eun;Park, Sun-Ok;Park, Sun-Min;Ko, Byoung-Seob
    • Applied Biological Chemistry
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    • v.50 no.4
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    • pp.352-357
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    • 2007
  • For a correlation to study the five tastes and efficacies in oriental medicine concepts, we used herbal medicines with bitter taste character in traditionally effective and experimental methods. In this study, we tested the in vitro effect of 20 typical kinds of herbal medicines with bitter taste on platelet aggregation induced by collagen in human whole blood using the impedance method of aggregometry. Among them, 3 kinds of hot water extracts and 2 kinds of 70% ethanol extracts showed the significant inhibiting effect on whole blood aggregation $(^{***}p<0.001)$. In particular, Coptidis Rhizoma (Coptis chinensis) extracts were selected as the most effective candidate with a strong grade of bitter taste through the sensory test of trained panels. The results from this experiment provide pharmacological evidence for the traditional use of bitter tasting herbs with traditional medicine theory, suggesting that strong bitter taste herbs could be help problems of blood circulation more than mild bitter tasting herbs.

The Effects of Goal Incongruity between Franchisor and Franchisee on Regulatory Focus, Performance, and Opportunism of Franchisee (프랜차이즈 본부와 가맹점 간 목표불일치가 가맹점의 조절초점, 성과, 그리고 기회주의에 미치는 영향)

  • Lee, Byong-Kwan Steven;Oh, Sejo;Kim, Sang-Duck
    • Journal of Distribution Science
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    • v.12 no.2
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    • pp.39-47
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    • 2014
  • Purpose - The ultimate goal of a franchise system comes from its win-win strategy. Agency theory uses goal incongruity to examine complex contracting problems between buyers and suppliers. Goal incongruity within a contractual relationship can be defined as the agent's desire not to cooperate. It is the degree to which the contractual terms do not satisfy the agent's goals. The greater the goal incongruity between the agent and the contract, the more likely it is that the agent will meet the terms of the contract. Thus, goal incongruity between buyers and suppliers has close relationships with both behavioral and financial performance. This study tries to examine these relationships in the franchise context using a model including related variables, such as regulatory foci, financial performance, and opportunism, to explain the reasons that not all franchisees perform their best. In particular, the study examines the effects of goal incongruity on regulatory focus, and the effects of regulatory focus on performance and opportunism. In short, the objective is to determine goal incongruity's effect on regulatory foci, and the effect of regulatory focus on performance and opportunism. Research design, data, and methodology - This study used data collected from the franchisee managers of 104 franchisors in South Korea. The franchisors include more than 10 franchisees, the majority of whom have been in business for more than five years. The study also surveyed 104 franchisees, matched with their franchisors for the sake of a dyadic approach. The study used regression analysis to test the hypotheses. Results - H1 and H2 predicted that goal incongruity would decrease promotion focus and increase prevention focus. Supporting H1, the result indicates goal incongruity had a positive effect on promotion focus. However, H2 was not supported. Goal incongruity had no significant effect on prevention focus (β = -.375, t = -4.331 and β = -.145, t = -1.950, respectively). H3 and H4 predicted that promotion focus would increase financial performance and decrease opportunism. Supporting these hypotheses, the results indicate that promotion focus had a positive effect on financial performance and a negative effect on opportunism (β = .771, t = 7.899 and β = -.765, t = -6.778, respectively). H5 and H6 predicted that prevention focus would decrease financial performance and increase opportunism. However, the results do not support these hypotheses. The results indicate that prevention focus had no effects on opportunism or financial performance (β = -.130, t = -1.070 and β = .090, t = .641, respectively). Overall, the evidence generally supported the hypotheses. Conclusion - Goal incongruity between a franchisor and a franchisee increases the franchisee's financial performance and opportunism, and the relationship is mediated by promotion focus. Interestingly, however, prevention focus has no mediating effect between goal incongruity and performance. Even though no significant relation exists between goal incongruity and prevention focus, the results have two implications. First, decreasing goal incongruity can improve financial performance and suppress franchisee opportunism. Second, the relationship between goal incongruity and performance affects promotion-focused franchisees.

A Study on the Belief Function Model (신념함수모형(信念函數模型)에 관한 연구)

  • Kim, Ju-Taek
    • Korean Business Review
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    • v.14
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    • pp.31-44
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    • 2001
  • The purpose of auditing is to express an auditor's opinion on the fair presentation of the financial position and business operations of companies according to the financial accounting standards, and to raise the reliability of the financial statements and to enable the user of the financial statements to make a proper judgement on the companies. There should be an audit risk in the audit of the financial statements in a modem sense because it is done by the sampling audit not by the detailed one. Audit risk is the risk that an auditor may unknowingly fail to modify appropriately the auditors' report on financial statements containing a material misstatement. The audit risk eventually hurt the reliability of the financial statements when the auditors set up different audit risks because it is determined by the auditor's professional judgement. Thus, there have been negative opinions on the Audit Risk Model suggested in the SAS No. 47 because it cannot explain the process of auditor's judgement and bring different results. In view of the results so far achieved, which influences the auditor's decision making, should be done by the Belief Function Mode Model in a position of raising the reliability of the financial statements and emphasizing the usefulness and effectiveness of the auditing.

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Development and Application of Assessment Items for the Diagnosis of Difficulties in Learning Elementary Mathematics (초등학교 수학 학습 어려움 진단을 위한 평가 문항 개발 및 적용 연구)

  • Kim, Hee-jeong;Cho, Hyungmi;Ko, Eun-Sung;Lee, Donghwan;Cho, Jinwoo;Choi, Jisun;Han, Chaereen;Hwang, Jihyun
    • Journal of the Korean School Mathematics Society
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    • v.25 no.3
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    • pp.261-278
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    • 2022
  • The purpose of this study is to develop an assessment to diagnose difficulties in learning mathematics and misconstructions that elementary students have. With thorough theoretical background and analysis of mathematics curriculum documents, we established learning trajectories for the following content areas in grades 3 to 6: number and operation, regularity, data and chance, geometry, and measurement. Then, the research team created the assessment items targeting a specific stage in the learning trajectories and including item options to identify possible misconceptions. Based on the unified validity theory, we reported the detailed procedure of the assessment development and the evidence for the content, substance, and structural validity of the assessment. We collected the data of 675 elementary students. Rasch measurement modeling was applied, and Cronbach's alpha was estimated. We considered how to report students' assessment results to teachers appropriately and immediately, which suggested important implications for supporting teaching and learning mathematics in elementary schools. We also suggested how to use the assessment developed in this study in online and distance learning environments due to the COVID-19 pandemic.

On the Effect of Extended Human Group Scale in Perception of Group Ratio and Size at Majority-biased Social Learning (인구 집단의 스케일의 확장이 집단 비율 및 집단 크기 지각에 미치는 영향: 다수편향적 사회적 정보 활용을 중심으로)

  • Jaekyung Jang;Dayk Jang
    • Korean Journal of Cognitive Science
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    • v.34 no.1
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    • pp.39-66
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    • 2023
  • New media moved the place of social exchange to the Internet, allowing large groups to communicate in one place beyond the limits of time and space. Recent studies have also reported cases in which human social abilities do not keep up with the expansion of group scale through social media. In this context, current study investigated how human perception of social information is affected by the expansion of the group scale in the context of majority bias. Using Internet-based task, the psychological processes that group ratio and group size are perceived and affect majority-biased social information use were investigated, and whether group scale moderates those processes was examined. The group ratio has a positive effect on the majority bias, and the relationship was partially mediated by ratio perception. Group scale did not moderate the relationship between group ratio and ratio perception. On the other hand, the correlation between group size and majority-biased social information use was not significant. Group scale moderates group size perception. The group size and size perception showed positive correlation under the smaller group scale condition. However under the extended group scale condition, the perceived group size became significantly lower and lost its correlation with group size. These results provide evidence that the psychological mechanism related to group size perception was not properly responding to the expansion of the group scale. Furthermore, the possibility of a specific psychological mechanism for processing group size information and the form of information input specifically accepted by majority bias were discussed from perspective of evolutionary psychology.

Studying Women's Experiences with Art Therapy Kits in the 2030s through Focus Group Interviews (포커스 그룹 인터뷰를 통한 2030대 여성의미술치료 키트 참여 경험 연구)

  • Kim, Bohyun;Park, Boram
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.5
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    • pp.275-290
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    • 2023
  • We aimed to revise and supplement the art therapy kit based on the findings of a review of women's experiences participating in the art therapy kit in the 2030s. After women in their 2030s experienced the developed art therapy kit for one month, we organized two homogeneous groups of 8 art psychotherapy majors and 5 non-majors to collect data through focus group interviews and analyzed them using grounded theory methods. In the end, 100 converted meaning units, 16 subcomponents, and 5 components were derived. There is a lack of research on the development and experience of art or art therapy-based kits in Korea, so it is important for us to provide basic data on the experience of art therapy kits. In addition, the study participants experienced insights into themselves and their emotions based on the accumulated art therapy kit outputs through immersion in emotion exploration and recognition, and these experiences led to the participants' recognition of the need and value of developing art therapy kits. The individual and unique outcomes of the art therapy kits became evidence of self-awareness, confirming the therapeutic effectiveness of art therapy kits as a tool for emotion exploration and recognition and for emotional change and resolution.

A Study on the Characteristic of Indoor Green-Wall Design - With Focused on Preference of Emotional Image Language - (실내 벽면녹화디자인 특성 연구 - 감성이미지 언어에 따른 선호도를 중심으로 -)

  • Lee, Ji-Hyun;Jang, Young-Soon
    • Science of Emotion and Sensibility
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    • v.14 no.4
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    • pp.593-604
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    • 2011
  • This study examines potential growth and different perspectives on green-walls, which are being re-evaluated recently. The aim is to identify the viewer preferences concerning the walls by collecting a wide spectrum of information to create an interior design related comprehensive and intellectual database. Also based on this proposition, choosing a green surface of indoor wall as a specific example stimulus, identifying a relationship betweeationsviewer's preference factors. The relationship will formulate detailed and absolute qualities, which will reach potential areas that the green walls can be widely applied in. As a result of a factor analysis, the viewers classified into the 3 factors as is pleasant, gorgeous and rich about the stimulus. Preferred key factors, which are closely related to emotional image language, were; cool, tidy, comfortable and beautiful. The common factors in preferred design stimulus, in order of importance are color>elements>image/form/plants. Specific levels of design factors according to relevance are contrast>furniture> modern>central/creeper foliage plants. In the meantime, this study is leading the process of quantitative measurement of green-walls to a new design direction and it is critical to consistently experimenting to back up the theory with solid evidence.

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Enforcement of Arbitral Agreement to Non-Signatory in America (미국에 있어서 비서명자에 대한 중재합의의 효력)

  • Suh, Se-Won
    • Journal of Arbitration Studies
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    • v.18 no.1
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    • pp.71-96
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    • 2008
  • Arbitration is fundamentally a matter of contract, whereby contractual parties may only be required to submit a dispute to arbitration pursuant to their formal agreement. However, there are several important exceptions to this rule that have developed under common law notions of implied consent. These doctrines may serve either to benefit or to harm a nonsignatory to an arbitral agreement because either (1) the nonsignatory may compel a signatory to the agreement to arbitrate a dispute or (2) the nonsignatory may be compelled to arbitrate a dispute despite never having signed an arbitration agreement. The Court has a long-standing domestic policy of favoring arbitration, and these doctrines reflect that policy. 1. incorporation by reference An arbitration clause may apply to a party who is a nonsignatory to one agreement containing an arbitration clause but who is a signatory to a second agreement that incorporates the terms of the first agreement. 2. assumption An arbitration clause may apply to a nonsignatory who has impliedly agreed to arbitrate. Under this theory, the nonsignatory's conduct is a determinative factor. For example, a nonsignatory who voluntarily begins arbitrating the merits of a dispute before an arbitral tribunal may be bound by the arbitrator's ruling on that dispute even though the nonsignatory was not initially required to arbitrate the dispute. 3. agency A nonsignatory to an arbitration agreement may be bound to arbitrate a dispute stemming from that agreement under the traditional laws of agency. A principal may also be bound to arbitrate a claim based on an agreement containing an arbitration clause signed by the agent. The agent, however, does not generally become individually bound by executing such an agreement on behalf of a disclosed principal unless there is clear evidence that the agent intended to be bound. 4. veil piercing/alter ego In the corporate context, a nonsignatory corporation to an arbitration agreement may be bound by that agreement if the agreement is signed by its parent, subsidiary, or affiliate. 5. estoppel The doctrine of equitable estoppel is usually applied by nonsignatory defendants who wish to compel signatory plaintiffs to arbitrate a dispute. This will generally be permitted when (1) the signatory must rely on the terms of the contract in support of its claims against the nonsignatory, or (2) the signatory alleges that it and the nonsignatory engaged in interdependent misconduct that is intertwined with the obligations imposed by the contract. Therefore, this article analyzed these doctrines centering around case-law in America.

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Determinants of Korea's Goods Balances with Japan: Evidence from Dynamic Panel Model (동태 패널모형을 이용한 대일 상품수지 결정요인 분석)

  • Kim, Jounggu;Hwang, Shinmo
    • International Area Studies Review
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    • v.15 no.2
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    • pp.331-350
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    • 2011
  • This paper analyzes balance of goods for a panel data of 56 industry classification in the MTI from 1980 to 2009. This study also develops the equilibrium adjustment process, which is a trade-off between the adjustment costs towards equilibrium costs for balance of goods and the cost of being in disequilibrium. In this framework, the GMM estimation procedure is used to estimate this dynamic panel model consistently. It is found that equilibrium balances of goods in Korean adjust to the speed is very slow to 0.0389. because of this is necessary to adjust the equilibrium goods balance as the cost of goods balance deficit is larger than by the cost. In addition, the real income elasticity for goods balance of resin in Japan and Korea, the real income elasticity 4.38168 and -0.835225, respectively, the marks were consistent with economic theory. The exchange rate elasticity of goods balance in japan to 0.478435 were found in the inelastic.