• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제21권3호
• /
• pp.147-152
• /
• 2010

Objectives : The purpose of this study was to investigate the deficits in executive function in children with ADHD and anxiety disorder, and further, to characterize executive function deficits among the two groups. Methods : Subjects consisted of 60 children between the ages of 5 and 14 (16 Normal, 24 ADHD, 20 Anxiety Disorder). Neuropsychological tests (KEDI-WISC, CCTT, STROOP, WCST, ROCF) for assessing cognitive and executive function were individually administered to all subjects. Results : There were no significant differences in FSIQ or PIQ among the three groups. However, the ADHD group tended to score lower on the VIQ and subtest of similarity, vocabulary, and digit span tests. The three groups did not significantly differ with respect to CCTT test results. On the STROOP test, the ADHD group showed poor performance on the word, color, and color-word subtests. The three groups did not exhibit significant differences in WCST test results ; however, the anxiety group performed poorly belonging to below 25 percentile rank on perseverative response. On the ROCF test, the ADHD group performed poorly with respect to their organization score and in particular, regarding copy and immediate recall. The anxiety group also performed poorly with regard to organization ; however, this was limited only to immediate recall. Conclusion : Children with ADHD displayed poor inhibition and organizational abilities compared to children with anxiety and normal controls. Further, children with anxiety disorder exhibited low cognitive flexibility and voluntary problem-solving abilities compared to ADHD children and normal controls. Based on these results, we suggest that the characteristics of executive dysfunction in ADHD and anxiety disorder in children are different.

• 동국한의학연구소논문집
• /
• 제3권
• /
• pp.237-267
• /
• 1994

The purpose of this study is the approach to I.I.C.P. centered on the meaning of consciousness disorder and the pathological aspect of Kwul (Jose consciousness ; faint, fall into a coma). The meaning of consciousness disorder and apoplexy is evidently involved the definition of Kwul. 1. It is found that the etymological interpretation on Kwul which the energy rises back to go through blocked space and the meaning interpretation of regarding Kwul as apoplexy with medical viewpoint, are related with consciousness disorder and motor disturbance in IICP in the aspect of the rise of Kwul and the abnormal rising of vital energy and blood, In addtion, the overall of meaning of Kwul is showed in table <1-1> by reference to doctors of many generations, 2. The pathology of Kwul includes abnormal rising, sthenia-syndrome in the upper part and asthenia in the lower, the origin of Kwul, the lower, looking like Yin by too sthenic Yang and looking like Yang by too sthenic Yin. The headache, vomiting, papilledema, paralysis of nervi craniales, coma, blood pressure rising, tachycardia by I.I.C.P can be regarded as a conception of trouble of vital energy, sthenia-syndrome of Kwul. The pulse pressure, brachycardia, bradypnea can be regarded as the conception of looking like Yin by too sthenic Yang. 3. In the emergency of Kwul, the abnormal ternimal reversion of the Kwulyin channel, Kuyang channel, and three Yins are related with the phenomenon in I.I.C.P. It is considered that the reverse movement of materials, I.I.C.P. can be closely observed by giving meaning on the meridian of Kwul in Somunkwulron. And the content of phrases of Naelyung which includes consciousness disorder refered in the chapter of Kwul, is compared with I.I.C.P. 4. The followings should be considered; examination of optic symptom and abnormal posture in cerebral herniation ; understanding and working out counterplans of factors and symptoms of consciousness disorder by the observation of vital sign, check of general stages, neurologic inverstigation, clinical diagnosis, and subsidiary diagnosis; application of morphological change of opinion; addtion of the conception of demonstration centered on Yunkyung, Samyinkwulruk, asthenia and thenia of healthy energy in oriental medicine. 5. The similarity of Kwul and I.I.C.P. can be found from etiology and pathotenic factor. The similarity is clearly found by investigation of etiology, pathotenic factor, symptoms and thrapy of Kwul, disease symptom ar.d other symptoms.

• 한방안이비인후피부과학회지
• /
• 제15권1호
• /
• pp.162-175
• /
• 2002

Aromatherapy is used in many diseases nowdays. And, Aromatherapy is similar to historical oriental medicine. Moreover, Aroma is a popular alternative medicine like oriental medicine in these days. We used for all kinds of diseases with aroma herbs, especially in ENT and dermatological disese. We must be a bridge over oriental and western medicine with aromatherapy, because it will help reduce stress in pschosomatic disorder. We have to accept aromatherapy as oriental medicine paradigm for better holistic medicine. Method :We analyzed 20 herbs difference and similarity both aroma herb and oriental herb. We reseach for a scientific name, family, therapeutic region, efficacy, perfumery note, nature. The results were as follows: 1. Most of herbs are similar to each other in the treatment. Top, middle, bottom is similar to sam-cho(三焦) sang-cho, zhong-cho, ha-cho, and But futher reseach is needed for development of Oriental medicine. 2. We find out much similarity between oriental herbs and aromatic herbs and qi-mi ron(氣味論) is useful to analyze them 3. We find out difference mechanism between GI absortion and nasal inhalation. 4. Other Aroma herbs must be analyzed by oriental oriental medical thought, for example, seung-gang-bu-chim(昇降浮沈), gui-gyong(歸經), and so on. 5. Aromatic oriental medicine ways are developed like aromatic therapy.

• 한국한의학연구원논문집
• /
• 제1권1호
• /
• pp.179-207
• /
• 1995

Homoeopathy ws established in 1796 by German phsician Samuel Hahnemann$(1755{\sim}1843)$. This method is an alternative form of therapy involving treatment by natural remedies. The basic principles of homoeopathic medicine, 'similia similibus curentur', 'experimenta in homine sano', 'dose minimae' and 'unitas remedii', are founded upon the idea of illness as a disorder of the internal equilibrium at the physical, mental and psychic levels. The three distinguishing characteristics of homopathy are that remedies are prescribed on the totlity of a person's symptoms, that the remedy likely to cure a person is a dilution of that substance which would cause the same symptoms in a healthy person, and that remedies are prepared using mcirodoses of substances which are diluted and then vigorously shaken. This paper describes the historical background of homeopathy and compared with the basic principles of oriental medicine from the literature.

• 생물정신의학
• /
• 제18권2호
• /
• pp.61-71
• /
• 2011

Substance addiction is a chronically relapsing disorder that has been characterized by a vicious cycle composed of intoxication, craving/anticipation, withdrawal, and response inhibition/bingeing. Here we summarize the findings from neuroimaging studies in addiction according to these behavioral components and suggest the integrated neurobiological model of drug addiction and related brain correlates. The roles of various prefrontal regions, thalamus, memory circuit, anterior cingulated, and insula were also suggested in addition to those of classical mesolimbic dopaminergic system and its responsivity. Limited studies of behavioral addiction demonstrated a similarity with substance addiction on the neurobiological basis. Based on the current understanding of neurobiology of addiction, further researches on interactions of behavioral components and their brain correlates, behavioral addiction, and therapeutic applications will be desired.

• 디지털융복합연구
• /
• 제17권12호
• /
• pp.509-521
• /
• 2019

본 연구는 인지행동치료(Cognitve Behavioral Therapy: CBT)분야 학술지에서 나타난 키워드의 출현패턴을 조사하여 국내 CBT 연구의 지식구조를 규명하는 데에 목적이 있다. 국내·외에서 수행된 CBT 연구를 비교하고자 '인지행동치료'에서 출판된 논문 234편(2008-2019)과 'Cognitive Therapy and Research'에서 출판된 논문 2,316편(1977-2019)이 수집되었다. 자료는 NetMiner 4.3 프로그램으로 분석되었으며 동시출현단어 분석은 코사인 유사도 행렬을 산출하고, 네트워크를 시각화하는 절차로 수행되었다. 본 연구의 결과로 국내 CBT연구자들의 주요 관심사가 식별되었고, 국내 CBT 지식구조는 9개의 연구영역으로 범주화되었다: '척도 타당화', '완벽주의와 속박감', '조현병 환자의 인지, 정서, 관계적 특성', '경계선 성격장애와 우울/양극성 장애 환자의 인지적 특성과 치료', '적응과 심리적 건강', '사회불안장애 환자의 인지적 특성과 치료', '우울의 원인과 공존이환', '수용전념치료', '폭식 장애 환자의 이해와 치료'. 본 연구는 지난 11년 동안 국내 CBT 분야에서 축적된 지식을 점검하였다는 데에 의의가 있으며 국내 CBT 연구의 향후 발전과제로 임상적 실천 표준을 제고하기 위한 연구가 필요하다고 제안한다.

• Journal of Microbiology and Biotechnology
• /
• 제28권11호
• /
• pp.1800-1805
• /
• 2018

Inflammatory bowel disease, including Crohn's disease and ulcerative colitis (UC), is a chronically relapsing inflammatory disorder of the gastrointestinal tract. Intestinal epithelial cells (IECs) constitute barrier surfaces and play a critical role in maintaining gut health. Dysregulated immune responses and destruction of IECs disrupt intestinal balance. Dextran sodium sulfate (DSS) is the most widely used chemical for inducing colitis in animals, and its treatment induces colonic inflammation, acute diarrhea, and shortening of the intestine, with clinical and histological similarity to human UC. Current treatments for this inflammatory disorder have poor tolerability and insufficient therapeutic efficacy, and thus, alternative therapeutic approaches are required. Recently, dietary supplements with probiotics have emerged as promising interventions by alleviating disturbances in the indigenous microflora in UC. Thus, we hypothesized that the probiotic Bifidobacterium animalis subsp. lactis strain BB12 could protect against the development of colitis in a DSS-induced mouse model of UC. In the present study, oral administration of BB12 markedly ameliorated DSS-induced colitis, accompanied by reduced tumor necrosis factor-${\alpha}$-mediated IEC apoptosis. These findings indicate that the probiotic strain BB12 can alleviate DSS-induced colitis and suggest a novel mechanism of communication between probiotic microorganisms and intestinal epithelia, which increases intestinal cell survival by modulating pro-apoptotic cytokine expression.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제3권1호
• /
• pp.75-83
• /
• 2000

저자들은 주기성 구토증으로 진단된 3명의 소아에서 6년 이상의 장기 추적관찰을 통하여 임상양상의 다양한 변화과정을 관찰하여 보고, 뇌파검사의 이상소견을 근거로 이형 편두통의 형태로 진행하여 가는 과정을 관찰하였다. 시간의 경과에 따라 구토 발병 주기, 기간의 변화와 함께 위배출능 저하, 두통의 발현, 뇌파의 이상 등 다양한 임상 양상의 변화를 보여주며, 2례에서는 증상의 소실이 관찰되었다. 특히, 뇌파 검사상 증상 발현시 발생하는 서파는 편두통의 발생 직전에 뇌혈류의 감소로 발생하는 양상과 매우 유사하며, 주기성 구토증과 편두통의 관련성을 시사하여 주는 소견으로, 진단 및 치료적 접근시 반드시 고려하여야 한다. 주기성 구통증은 이형 편두통으로의 이행 과정인가?

• 정신신체의학
• /
• 제11권1호
• /
• pp.36-43
• /
• 2003

연구목적: 본 연구의 목적은 외상후 스트레스 장애에서 증상의 정도에 따른 인지기능의 차이가 어떠한지에 대하여 연구한 것이다. 방 법: 교통사고 관련 외상후 스트레스 장애로 진단된 90명의 외래, 입원환자를 대상으로 외상후 스트레스 장애 증상의 심각도(MMPI 우울증 척도, 강박 척도, 정신분열증 척도)와 인지기능(K-WAIS)을 측정하였다. 그들을 MMPI 우울증 척도, 강박증 척도, 정신분열증 척도 점수에 따라 상위 30%에 해당하는 집단과 하위 30%에 해당하는 집단으로 구분하여 두 군간의 지능과 소검사 점수 차이에 대하여 각각 검증하였다. 결 과: 우울증 척도의 상위군과 하위군 사이에 유의한 차이는 없었다. 그리고 강박 척도에서 하위군이 상위군보다 기본지식, 어휘문제, 공통성문제, 빠진곳 찾기, 차례맞추기가 유의하게 높았다. 그리고 정신분열증 척도에서 하위군이 상위군보다 전체지능, 언어성지능, 동작성지능, 기본지식, 어휘문제, 이해문제, 산수문제, 빠진곳 찾기, 차례맞추기, 토막짜기, 모양맞추기, 바꿔쓰기가 유의하게 높았다. 결 론: 본 연구 결과, 외상후 스트레스 장애에서 증상의 정도에 따른 인지기능의 차이가 있었다. 따라서 증상의 정도가 심한 집단에서 인지기능 장애가 더 심하다는 것을 알 수 있었다. 그러므로 외상후 스트레스 장애는 불안장애이기도 하지만 인지기능 또한 증상에 의해 많은 영향을 받는다는 것을 알 수 있었다. 향후 외상후 스트레스 장애를 치료함에 있어서 약물치료 뿐만이 아니라 다양한 인지적 치료 접근이 필요할 것으로 생각된다.

• 동의생리병리학회지
• /
• 제19권5호
• /
• pp.1129-1136
• /
• 2005

The writer reports the conclusions gained from study about the cause of the hypersensitive large intestine syndrome with Dongeuibogam as the central figure through researching the disharmony among Body Essence, Vital Energy, Mentality, and Blood, mutual action of five viscera and six bowels, and external shapes. The hypersensitive large intestine syndrome is generally chronic and recurred in many cases, so it is more efficacious than symptomatic to treat according to find the contradictions of individual shapes. The shapes and cases suffering frequently the hypersensitive large intestine syndrome are Gi-kwa and Sin-kwa, having a long nose, having a bruised spot on Triple warmer, man with inclined mouth, Taeeum type, man with congested fluids, man with colic symptoms. The hypersensitive large intestine syndrome in Oriental medicine is recognized of diarrhea, constipation, abdominal pain, abdominal distention and fullness caused by seven emotions. In Dongeuibogam it can be found out the similarity in depressive symptoms due to disorder of Gi, stagnation of Gi, dysphasia due to disorder of Gi, diarrhea due to disorder of Gi, fullness of due to Gi, diarrhea due to phlegm-retention, retention of undigested food, immoderate drinking, hypo-function of the spleen, or deficiency, abdominal pain from colic symptom, and difficulty in defecation and urination, internal injury, diarrhea due to weakness and fatigue. If the Jung, Gi, Sin, and Hyul composed the human body is broken harmony, the function of large intestinal transmission would be fallen, so similar symptoms like the hypersensitive large intestine syndrome are gotten. Especially Gi-kwa suffers diarrhea, constipation abdominal pain, and abdominal distention and fullness due to depressive symptoms from disorder of Seven emotions or Seven Gi. And Sin-kwa suffers from the hypersensitive large intestine syndrome due to emotional restlessness having an influence on rhythmic movement of abdomen. Examining between five viscera and six bowels and the hypersensitive large intestine syndrome, Liver cannot disperse well having influence on mutual relation of Liver-Large intestine, Heart reduces the function of defecation and urination not to control the seven emotions, Lung having exterior and interior relation with intestine has an influence on primordial energy and let the main symptoms occur, Spleen circulating the body fluid let the main symptoms occur due to malfunction of circulation, Kidney locating in lower part of the body has deep connection with intestine, so let the disorder. Urinary bladder is connected with intestine in moisture metabolism, Stomach is connected in receive and transmission, Small intestine is connected in absorption and excretion, from small intestine pain disturbing the abdominal movement, Samcho managing the catharsis of lower heater if declined its function causes the hypersensitive large intestine syndrome. The colic symptoms of Front private parts which disorder in lower abdomen give rise to abdominal pains, difficulty in defecation and urination due to Cold are similar to the hypersensitive large intestine syndrome. The treatments of applying the shapes of colic syndrome advocated by Master Park can be efficacious cure in clinic. Researching after the clinical cases of Master Park advocating Hyungsang medicine, we came to know that plenty of prescriptions of internal injury are applied and take good effects.