• Molecules and Cells
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• v.46 no.2
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• pp.106-119
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• 2023

With the increased number of single-cell RNA sequencing (scRNA-seq) datasets in public repositories, integrative analysis of multiple scRNA-seq datasets has become commonplace. Batch effects among different datasets are inevitable because of differences in cell isolation and handling protocols, library preparation technology, and sequencing platforms. To remove these batch effects for effective integration of multiple scRNA-seq datasets, a number of methodologies have been developed based on diverse concepts and approaches. These methods have proven useful for examining whether cellular features, such as cell subpopulations and marker genes, identified from a certain dataset, are consistently present, or whether their condition-dependent variations, such as increases in cell subpopulations in particular disease-related conditions, are consistently observed in different datasets generated under similar or distinct conditions. In this review, we summarize the concepts and approaches of the integration methods and their pros and cons as has been reported in previous literature.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2008.05a
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• pp.253-259
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• 2008

RFID is a generic term for technologies which use RF waves to identify, track, or categorize any object. A radio frequency identification (RFID) reader recognizes objects through wireless communications with RFID tags. Tag collision arbitration for passive tags is a significant issue for fast tag identification due to communication over a shared wireless channel. One of the research areas in RFID system is a tag anti-collision protocol. In this paper, various anti-collision protocols are discussed. The pros and cons of different anti-collision protocols are compared with each other and their performance is analyzed and the better performance anti-collision protocol is suggested.

• Asia pacific journal of information systems
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• v.13 no.1
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• pp.23-46
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• 2003

Today ordinary consumers have the option of buying the products/services through Internet commerce, home shopping, or traditional commerce. This study compares the means-ends objective measures comprising the customer satisfaction with each type of commerce. Means objective variables consist of product variety, impulsive buying, comparison shopping, product information, and accuracy of transaction. Ends objective variables include convenience, safety, time saving, cost reduction, and shopping enjoyment. Results of data analysis indicate that ends objective variables are directly related with the behavioral intention of customers, and that each type of commerce has its own pros and cons which in turn provides the basis for differentiated customer satisfaction.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.32B no.7
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• pp.966-973
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• 1995

In this paper, we compare several methods for implementing a VHDL design database through a case study on VHDL tool development system. We implemented three versions of the VHDL design database which the VHDL tool development system is based on. The first version was coded in the C programming language following value-oriented paradigm. The second one was coded in the C++ programming language following object-oriented paradigm. The third one was implemented using an existing object-oriented database. Based on our experience, we present quantitatively the pros and cons of each implementation method. The value-oriented version was most difficult to implement but showed good performance. Compared to the value- oriented version, the C++ version was twice as easy to implement and showed about the same performance. Using an existing object-oriented database allowed easiest implementation but resulted in a 1.5 to 6 times slower version.

• Interdisciplinary Bio Central
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• v.1 no.3
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• pp.11.1-11.5
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• 2009

One of the main issues of molecular evolution is to reveal the principles dictating protein evolutionary rates. A traditional hypothesis posits that protein evolutionary rates are mostly determined by the average functional importance of amino acids in a given protein. Thus the correlations of evolutionary rates with different variables such as PPI, gene essentiality and expression abundance have been studied to test the traditional hypothesis. Recently, mRNA expression abundance among the variables has drawn much attention, not only because it shows relatively strong correlation with protein evolutionary rates, but also because of the controversies surrounding an alternative hypothesis against the traditional one. Here, I will give an overview over the traditional hypothesis, and summarize the different variables that have been found to correlate with protein evolutionary rates. Then I will introduce pros and cons on the two different hypotheses.

• Proceedings of the KIPE Conference
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• 2015.07a
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• pp.193-194
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• 2015

In this paper, the solid state pulsed power modulator developed in KERI, which is based on IGBT technologies are overviewed. During last ten years, several kinds of solid state modulators were developed in KERI such as IGBT stacks with step up transformer, full IGBT stack based marx generator, modified IGBT marx generator and high repetitive solid state modulator. Basic principle of the design is described and each pros and cons are compared. KERI's solid state pulsed power modulators has lot of advantages for industrial pulsed power application focused on everlasting life cycle and high repetitive, and shows superior arching protection ability.

• Proceedings of the KIEE Conference
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• 2011.07a
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• pp.568-569
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• 2011

As an answer for need for minimizing the road excavation of a box type tunnel, a method of vertical snake was developed, which is very economical and easy to construct. The reason why it is good is, the road excavation width, steel accessories, the road occupation space decreases with the technology. The pros and cons of 345kV XLPE $2,500mm^2$ horizontal and vertical snake are listed below. In this study, topics such as 345kV XLPE $2,500mm^2$ vertical snake construction standard and the development process of steel accessories, vertical snake construction procedure will be covered.

• Communications for Statistical Applications and Methods
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• v.26 no.3
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• pp.315-323
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• 2019

Panel data sets have recently been developed in various areas, and many recent studies have analyzed panel, or longitudinal data sets. Often a dichotomous dependent variable occur in survival analysis, biomedical and epidemiological studies that is analyzed by a generalized linear mixed effects model (GLMM). The most common estimation method for the binary panel data may be the maximum likelihood (ML). Many statistical packages provide ML estimates; however, the estimates are computed from numerically approximated likelihood function. For instance, R packages, pglm (Croissant, 2017) approximate the likelihood function by the Gauss-Hermite quadratures, while Rchoice (Sarrias, Journal of Statistical Software, 74, 1-31, 2016) use a Monte Carlo integration method for the approximation. As a result, it can be observed that different packages give different results because of different numerical computation methods. In this note, we discuss the pros and cons of numerical methods compared with the exact computation method.

• Journal of the Optical Society of Korea
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• v.19 no.6
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• pp.555-559
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• 2015

Coherence length (time) is a key parameter in many classical and quantum optical applications. Two interferometers – Michelson and Young’s double-slit – are used to characterize the temporal coherence of single photons emitted from single terrylene molecules. For quantitative analysis, a dispersion-related distortion in the interference pattern of a Michelson interferometer is carefully corrected by a simple dispersion compensation. Additionally, it has been demonstrated that Young’s interferometer can be used in temporal coherence studies at the single photon level with high accuracy. The pros and cons of the two systems are discussed. The measured coherence lengths in the two systems are consistent with one another under the self-interference interpretations.

• Journal of Information Technology and Architecture
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• v.10 no.3
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• pp.379-386
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• 2013

This study is about the suggestion of reduction method for social insurance cost of startup SMEs based on the study abroad. We suggest several methods (direct and indirect support, exemption, deferment or loan) based on the pros and cons, government's financial situation, the ease of implementation and effectiveness of mitigation methods, creating conditions for the implementation of social insurance mitigation.